Jump to main content.


Tert-Amyl Methyl Ether (TAME) Test Results


Alphabetical Listing

A B C D E
F G H I bulletJ
bulletK bulletL M N O
P Q R S T
U V bulletW X bulletY
bulletZ
All
Chemical Testing Homepage

CAS No. 994-05-8

Consent Order (CO)
60 FR 14910; March 21, 1995
TAME Producers Group

Modifications/Notices
59 FR 18399; April 18, 1994/Solicitation for Consent Order
62 FR 35104; June 30, 1997/Technical Amendment

Project Manager: Gary Timm

Branch Chief: Frank Kover

Status: Awaiting test data.

Announced Receipt of Test Data

Test data were submitted by the American Petroleum Institute (API) pursuant to a Consent Order and received by EPA on July 11, 1996. The submissions include two final reports entitled: (1) “CHO/HGPRT Mutation Assay,” and (2) Chromosome Aberrations in Chinese Hamster Ovary (CHO) cells” (61 FR 42611; August 16, 1996).

Test data were submitted by the American Petroleum Institute (API) pursuant to a Consent Order and received by EPA on March 6, 1997. The submissions include two final reports entitled: (1) “Developmental Toxicity Evaluation of Inhaled Tertiary Amyl Methyl Ether (TAME) in CD (Sprague-Dawley) Rats,” and (2) Developmental Toxicity Evaluation of Inhaled Tertiary Amyl Methyl Ether (TAME) in CD-1 Mice” (62 FR 18350; April 15, 1997).

Test data were submitted by the American Petroleum Institute (API) pursuant to a Consent Order and received by EPA on September 3, 1997. The submissions include four final reports entitled: (1) “Tertiary Amyl Methyl Ether (TAME): Pilot Study (95063) for Metabolism, Distribution, and Pharmacokinetics in Male F-344 Rats after a Single Nose-Only Inhalation Exposure,” (2) Blood Pharmacokinetics of Tertiary Amyl Methyl Ether in Male and Female F-344 Rats and CD-1 Mice after Nose-Only Inhalation Exposure,” (3) “Tertiary Amyl Methyl Ether (TAME): Metabolism and Distribution in Male and Female F344 Rats and CD-1 Mice after Single or Repeated Inhalation or Gavage Exposures,”, and (4) A 13-Week Inhalation Toxicity/Neurotoxicity Study of Tertiary Amyl Methyl Ether in the Rat and Mouse via Whole-Body Exposures with a 4-Week Recovery Period” (62 FR 51858; October 3, 1997).

Results of Testing Table



Local Navigation


Jump to main content.