US/OECD Minimum Pre-Market Data/Structure Activity Relationships Study
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- Cover & Table of Contents (PDF) (4 pp, 553 KB)
- 1-3 Background, Project Design, EC & US Notification Schemes (PDF) (9 pp, 1062 KB)
- 4.1 Intro to Results, Evaluation Criteria, Complicating Factors (PDF) (2 pp, 556 KB)
- 4.2.1 Results Evaluation of Physico-chemical and environmental fate parameters (PDF)(7 pp, 859 KB)
- 4.2.2 Results Evaluation of Ecotoxicity parameters (PDF) (2 pp, 554 KB)
- 4.2.2.2 Results Evaluation of Classification Dangerous for the Environment (PDF) (3 pp, 550 KB)
- 4.2.3 Results Evaluation of Toxicological properties/health effects (PDF) (18 pp, 1283KB)
- 5.1 Conclusions US Perspective (PDF) (8 pp, 1119 KB)
- 5.2 Conclusions EC Perspective (PDF) ( 3 pp, 626 KB)
- Annex 1 US EPA and EC experts within this joint project (PDF) (2 pp, 489 KB)
- Annex 2 Companies which gave permission to use their substances data within this project (PDF) (3 pp, 562 KB)
- Annex 3 Generic chemical descriptions of the chemicals in this project (PDF) (6 pp, 598 KB)
- Annex 4 Boiling point test results vs. predictions (PDF) (11 pp, 714 KB) )
- Annex 5 Vapor pressure test results vs. predictions (PDF) (11 pp, 798 KB)
- Annex 6 Water solubility test results vs. predictions (PDF) (11 pp, 777 KB))
- Annex 7 Partition coefficient test results vs. predictions (PDF) (11 pp, 725 KB)
- Annex 8 Biodegradation test results vs. predictions (PDF) ( 11 pp, 715 KB)
- Annex 9 Toxicity to fish test results vs. predictions (PDF) (11 pp, 713 KB)
- Annex 10 Toxicity to Daphnia test results vs. predictions (PDF) (11 pp, 733 KB)
- Annex 11 Toxicity to algae test results vs. predictions (PDF) (1 p, 469 KB))
- Annex 12 Acute oral toxicity test results vs. predictions (PDF) (11 pp, 682 KB
- Annex 13 Skin and eye irritation test results vs. predictions (PDF) (11 pp, 837 KB)
- Annex 14 Systemic toxicity test results vs. predictions (PDF) (20 pp, 1075 KB)
- Annex 15 Mutagenicity test results vs. predictions (PDF) (12 pp, 759 KB)
- Appendix 1 Directive 67 548 EEC, sixth amendment (PDF) (19 pp, 1441 KB)
- Appendix 2 EC summary notification dossier (PDF) (57 pp, 1511 KB)
- Appendix 3 Annex VI to Directive 67 548 EEC (PDF) (34 pp, 2 MB)
- Appendix 4 Toxic Substances Control Act premanufacture notification (PDF) (31 pp, 7 MB)
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