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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received September 2001

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0901-01347 (PDF) Vanadium hydroxide oxide phosphate 65232-89-5 N DuPont Chemical Solutions Enterprise Results of a 90-day subchronic toxicity oral feeding study in rats
8EHQ-0901-15003A (PDF) Aryl ketone, substituted *2 Confidential N BASF Corporation Results of a 24-month dietary chronic toxicity and carcinogenicity study in rats
8EHQ-0901-15004A (PDF) Amino acid amide carbamate *2 Confidential NAmino acid carbamate metabolite Confidential NChemical Confidential N Confidential Summary of Ames reverse mutation assay
8EHQ-0901-15005A (PDF) Chemical Confidential   Confidential Preliminary results of prenatal and postnatal developmental toxicity studies in rats
8EHQ-0901-15006A (PDF) Benzene 71-43-2   ExxonMobil Corporation Results of an epidemiology study for lympho-hematopoletic cancer in Australian petroleum workers Y
8EHQ-0901-15007A (PDF) AMS 13839 None N Bayer Corporation Summary results of a pilot study on subacute inhalation toxicity in rats
8EHQ-0901-15008A (PDF) Acetoxysilane derivative, experimental Confidential N Confidential Results of a Buehler Sensitization Study in albino guinea pigs
8EHQ-0901-15009A (PDF) Monomethyl tin isooctylthioglycolate 54849-38-6 Y Rohm and Haas Company Results of a subchronic oral LD50 feeding study in day-old leghorn chickens
Monomethyl tin (mercaptoethyl oleate) sulfide None  
Monooctyltin tris (isooctylthio-glycolate) 26401-86-5 N
Dimethyl tin (mercaptoethyl oleate) sulfide None  
Dioctyltin bis (isooctylthio-glycolate) 26401-97-8 N
8EHQ-0901-15010A (PDF) Bis-(hydroxy-ammonium) sulfate 10039-54-0 N BASF Corporation Summary results of a 24-month carcinogenicity study in rats
8EHQ-0901-15011A (PDF) BYF13841 (Carboxamides) *2 None N Bayer Corporation Summary results of a developmental toxicity study in rats
8EHQ-0901-15012A (PDF) 2,3-Dichloro-5trichloromethyl-pyridine 69045-83-6 Y Dow Chemical Company Statement that a worker was diagnosed with occupational asthma and/or respiratory sensitization
8EHQ-0901-15013A (PDF) Cyclic ketoenols *2 None N Bayer Corporation Results of an oral gavage pilot developmental toxicity study in rats
8EHQ-0901-15014A (PDF) Bisphenol A-epichlorohydrin copolymer 25068-38-6 Y Society of the Plastics Industry, Inc. Results of a dermal sensitization study in guinea pigs and a description of epoxy resin chemical characteristics
Bisphenol A diglycidylether 1675-54-3 Y
Bisphenol A-epichlorohydrin copolymer 25036-25-3 Y
8EHQ-0901-15017A (PDF) Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Preliminary results of an aquatic toxicity screening study in green algae
8EHQ-0901-00373M (PDF) N-Ethyl perfluorooctanesulfonamid oethanol 1691-99-2 N 3M Company Amended analytical lab report on the determination of the presence and concentration of PFOS, M556, PFOSAA, and PFOSA in the liver and PFOS, M556, PFOSAA, PFOSA, and EtFOSE-OH in the sera of rats from a previously conducted 2-generation oral gavage reprod
8EHQ-0901-00373N (PDF) Perfluorooctanesulfonic acid, potassium salt 2795-39-3 N 3M Company Analytical laboratory report of determination of the presence and concentration of potassium perfluorooctanesulfonate in the serum and liver of rats exposed to PFOS by oral gavage during a combined fertility, developmental and perinatal/postnatal reproduc
8EHQ-0901-00373O (PDF) Fluorochemicals, sulfonate-based Multiple N 3M Company Final reports of an oral gavage reproductive and developmental toxicity study in rats,several biomonitoring studies in rats and rabbits, mortality study of workers, acute oral toxicity study in rats, and several bioaccumulation studies in environmental sp
8EHQ-0901-00373P (PDF) N-Methyl perfluorooctanesulfonamid oethanol 24448-09-7 Y 3M Company Analytical report of the determination of the presence and concentration of perfluorooctanesulfonate, perfluorooctanesulfonylamide, M556, and M570 in the liver and sera samples of rats of a 13-week dietary study.
8EHQ-0901-00373Q (PDF) N-Ethyl perfluorooctanesulfonamid oethanol 1691-99-2 N 3M Company Analytical laboratory report of the determination of the concentration of PFOS, PFOSA, PFOSAA, and EtFOSE-OH in sera and liver of rats exposed to N-EtFOSE by oral gavage in a developmental toxicity study.
8EHQ-0901-00373R (PDF) N-Ethyl perfluorooctanesulfonamid oethanol 1691-99-2 N 3M Company Analytical laboratory report on the determination of the presence and concentration of PFOS or another metabolite of N-EtFOSE in liver and serum specimens from a previously conducted developmental toxicity study in rabbits exposed to N-EtFOSE by oral gava N
8EHQ-0901-00373S (PDF) Fluorochemicals, perfluorooctanesulfonyl fluoride-based None Y 3M Company Final report on human exposure and mortality studies of workers employed at the 3M Decatur, AL Facility.
8EHQ-0901-00373T (PDF) Fluorochemicals, sulfonate-based None   3M Company Final report on an acute oral toxicity screen in rats.
8EHQ-0901-00373U (PDF) Fluorochemicals, perfluorooctanesulfonaterelated None   3M Company Final report on the accumulation of PFOS, FOSA, PFOA, and PFHS in fish tissues from the US and certain European countries.
8EHQ-0901-00373V (PDF) Fluorochemicals, perfluorooctanesulfonaterelated None   3M Company Final report on the accumulation of perflluorooctanesulfonate and related fluorochemicals in mink and river otters from the US.
8EHQ-0901-00373W (PDF) Fluorochemicals, perfluorooctanesulfonaterelated None   3M Company Final report on PFOS and related fluorochemicals in oyster, Crassostrea Virginica, from the Gulf of Mexico and Chesapeake Bay.
8EHQ-0901-00373X (PDF) Fluorochemicals, perfluorooctanesulfonaterelated None   3M Company Final report on the accumulation of PFOS and relaed fluorochemicals in fish-eathing water birds collected in the United States, Baltic and Mediterranean Seas, and Japanese and Korean coasts.
8EHQ-0901-00373Y (PDF) Fluorochemicals, perfluorooctanesulfonaterelated None   3M Company Final report on the accumulation of PFOS and related fluorochemicals in marine mammals.
8EHQ-0901-00373Z (PDF) Fluorochemicals, sulfonate-based None   3M Company Transmittal letter providing the final reports and other supplemental information related to previous TSCA Section 8(e) notifications.
8EHQ-0901-14523C (PDF) Perfluorobutanesulfonyl fluoride 375-72-4 N 3M Company Final report of a 28-day repeat dose inhalation toxicity study in rats
8EHQ-0901-14801B (PDF) C10-16 and C12-20 unsaturated alkyl ether derivatives with amino reaction products Unknown   Dow Corning Corporation Final report of an acute inhalation toxicity study in rats
8EHQ-0901-14822C (PDF) Pyrethroid *2 Confidential   Confidential Additional summary results of a 28-day toxicity study in rats
8EHQ-0901-14868C (PDF) Trifluoropropylmethylcyclo trisiloxane 2374-14-3   Dow Corning Corporation Results of an ongoing oral gavage 90day toxicity and one-generation reproductive toxicity study in rats
8EHQ-0901-14880B (PDF) Alcohols, C8-14, gammaomega-perfluoro 68391-08-2   DuPont Haskell Laboratory Results of an oral gavage developmental toxicity study in rats
8EHQ-0901-14880C (PDF) Alcohols, C8-14, gammaomega-perfluoro 68391-08-2   DuPont Haskell Laboratory Results of an oral gavage 90-day toxicity and one-generation reproductive toxicity study in rats
FYI-0901-01415A (PDF) Decalin 91-17-8 N National Institute of Environmental Health Sciences Pathology Working Group Report and pathology Summary Tables from two-year inhalation carcinogenicity and chronic toxicity studies in rats and mice

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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