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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received April 2002

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0402-13646 (PDF) Methyl t-butyl ether 1634-04-4 Y Lyondell Chemical Company Final report of an acute inhalation neurotoxicity study in humans
8EHQ-0402-15107A (PDF) p-Dichlorobenzene 106-46-7 Y Bayer Corporation Results of an in vivo DNA fragmentation assay (Comet assay) in rats
8EHQ-0402-15108A (PDF) 1-Aziridine-propanoic acid derivative 64265-57-2 N Bayer Corporation Results of an in vitro chromosome aberration test in Chinese hamster ovary cells
8EHQ-0402-15109A (PDF) Anthranilamide None N Confidential Results of an oral gavage pilot developmental toxicity study in rats
8EHQ-0402-15111A (PDF) 2-Hydroxypropylcycloheptaamylose 128446-35-5 N Wacker Chemical Corporation Final report of a 28-day inhalation toxicity study in rats
8EHQ-0402-15112A (PDF) Flocumafen *2 90035-08-8   Confidential Results of acute toxicity studies in rainbow trout, bluegill sunfish and daphnia
8EHQ-0402-15113A (PDF) Triazole, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in daphnia
8EHQ-0402-15114A (PDF) Aryl ketone, substituted *2 Confidential N BASF Corporation Results of acute toxicity studies in daphnia and green algae
8EHQ-0402-15115A (PDF) Triazole, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in daphnia
8EHQ-0402-15116A (PDF) Triazole, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in daphnia
8EHQ-0402-15117A (PDF) Aryl ketone, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in duckweed
8EHQ-0402-15118A (PDF) Triazole, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in daphnia
8EHQ-0402-15119A (PDF) Triazole, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in daphnia
8EHQ-0402-15120A (PDF) AU-358 LTV Confidential Y Sewer Sciences, Inc. Final report of a primary eye irritation study in rabbits
8EHQ-0402-15121A (PDF) 3-Phenoxybenzaldehyde 39515-51-0 Y BASF Corporation Results of an acute toxicity study in daphnia
8EHQ-0402-15122A (PDF) Toluene diisocyanate 26471-62-5 Y Dow Chemical Company Results of an inhalation subchronic sensitization study in mice to investigate mechanisms of asthmatic reaction
8EHQ-0402-15123A (PDF) Titanium, bis(2,4 pentanedionatokappaO, kappaO’) bis(2propanolato) 17927-72-9 N DuPont Haskell Laboratory Results of an acute oral toxicity study in rats
8EHQ-0402-15124A (PDF) Bis-(methyldiglycolato)bis-(triethanolamino)titanate Unknown   DuPont Haskell Laboratory Results of a 28-day subchronic oral gavage toxicity study in rats
8EHQ-0402-15125A (PDF) Diisopropyl ether 108-20-3 Y American Petroleum Institute 211(b) Research Group Preliminary results of a 4-week inhalation toxicity study in rats to evaluate immune system function
Gasoline 86290-81-5 Y
8EHQ-0402-15126A (PDF) 1-Butanol, titanium (4+) salt 5593-70-4 N DuPont Haskell Laboratory Results of an acute oral toxicity study in rats, a skin irritation study in rabbits and an eye irritation study in rabbits
8EHQ-0402-15127A (PDF) 2-Propanol, titanium (4+) salt 546-68-9 Y DuPont Haskell Laboratory Results of an acute oral toxicity study in rats and an eye irritation study in rabbits
8EHQ-0402-15128A (PDF) 1-Butanol, zirconium (4+) salt 1071-76-7 N DuPont Haskell Laboratory Results of an acute oral toxicity study in rats and a skin irritation study in rabbits
8EHQ-0402-15129A (PDF) Titanium, tetrakis (2-ethyl1,3-hexanediolato) 5575-43-9 N DuPont Haskell Laboratory Results of an acute oral toxicity study in rats
8EHQ-0402-15130A (PDF) 2-Propanol 67-63-0 Y DuPont Haskell Laboratory Results of an acute oral toxicity study in rats
Titanium, bis[2-[bis(2hydroxyethyl) aminokappaN] ethanolatokappaO] bis(2propanolato)- 36673-16-2 N
8EHQ-0402-00373AG (PDF) Ammonium perfluorooctanoate 3825-26-1 N 3M Company Final report of an oral gavage 2generation reproductive toxicity study in rats
8EHQ-0402-14862C (PDF) C4 crude butadiene, low butadiene content None   American Chemistry Council Final report of an inhalation bone marrow micronucleus test in mice
8EHQ-0402-14885B (PDF) 2-Phenylethyl alcohol 60-12-8 Y Lyondell Chemical Company Results of an acute intraperitoneal study in mice to evaluate the induction of cell proliferation by styrene metabolites
8EHQ-0402-15005B (PDF) Chemical Confidential Y Confidential Results of an oral developmental toxicity study in rats
8EHQ-0402-15009B (PDF) Organotin compounds Multiple N Rohm and Haas Company Response to EPA request for clarification of chemical identities and descriptions of studies
8EHQ-0402-15043B (PDF) C.I. Basic Violet 11 73398-89-7 N BASF Corporation Chemical identity, uses and MSDS in response to EPA request
FYI-0402-01428A (PDF) Compressed natural gas emissions Diesel emissions None None   International Truck and Engine Corporation Several reports on mutagenicity and compositional analysis
FYI-0402-01429A (PDF) Propylene glycol mono-tbutyl ether 57018-52-7 N National institute of Environmental Health Sciences Pathology Working Group report from a 2-year carcinogenicity and chronic toxicity study in rats (exposure route not stated)

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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