TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received April 2002
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|8EHQ-0402-13646 (PDF)||Methyl t-butyl ether||1634-04-4||Y||Lyondell Chemical Company||Final report of an acute inhalation neurotoxicity study in humans|
|8EHQ-0402-15107A (PDF)||p-Dichlorobenzene||106-46-7||Y||Bayer Corporation||Results of an in vivo DNA fragmentation assay (Comet assay) in rats|
|8EHQ-0402-15108A (PDF)||1-Aziridine-propanoic acid derivative||64265-57-2||N||Bayer Corporation||Results of an in vitro chromosome aberration test in Chinese hamster ovary cells|
|8EHQ-0402-15109A (PDF)||Anthranilamide||None||N||Confidential||Results of an oral gavage pilot developmental toxicity study in rats|
|8EHQ-0402-15111A (PDF)||2-Hydroxypropylcycloheptaamylose||128446-35-5||N||Wacker Chemical Corporation||Final report of a 28-day inhalation toxicity study in rats|
|8EHQ-0402-15112A (PDF)||Flocumafen *2||90035-08-8||Confidential||Results of acute toxicity studies in rainbow trout, bluegill sunfish and daphnia|
|8EHQ-0402-15113A (PDF)||Triazole, substituted *2||Confidential||N||BASF Corporation||Results of an acute toxicity study in daphnia|
|8EHQ-0402-15114A (PDF)||Aryl ketone, substituted *2||Confidential||N||BASF Corporation||Results of acute toxicity studies in daphnia and green algae|
|8EHQ-0402-15115A (PDF)||Triazole, substituted *2||Confidential||N||BASF Corporation||Results of an acute toxicity study in daphnia|
|8EHQ-0402-15116A (PDF)||Triazole, substituted *2||Confidential||N||BASF Corporation||Results of an acute toxicity study in daphnia|
|8EHQ-0402-15117A (PDF)||Aryl ketone, substituted *2||Confidential||N||BASF Corporation||Results of an acute toxicity study in duckweed|
|8EHQ-0402-15118A (PDF)||Triazole, substituted *2||Confidential||N||BASF Corporation||Results of an acute toxicity study in daphnia|
|8EHQ-0402-15119A (PDF)||Triazole, substituted *2||Confidential||N||BASF Corporation||Results of an acute toxicity study in daphnia|
|8EHQ-0402-15120A (PDF)||AU-358 LTV||Confidential||Y||Sewer Sciences, Inc.||Final report of a primary eye irritation study in rabbits|
|8EHQ-0402-15121A (PDF)||3-Phenoxybenzaldehyde||39515-51-0||Y||BASF Corporation||Results of an acute toxicity study in daphnia|
|8EHQ-0402-15122A (PDF)||Toluene diisocyanate||26471-62-5||Y||Dow Chemical Company||Results of an inhalation subchronic sensitization study in mice to investigate mechanisms of asthmatic reaction|
|8EHQ-0402-15123A (PDF)||Titanium, bis(2,4 pentanedionatokappaO, kappaO’) bis(2propanolato)||17927-72-9||N||DuPont Haskell Laboratory||Results of an acute oral toxicity study in rats|
|8EHQ-0402-15124A (PDF)||Bis-(methyldiglycolato)bis-(triethanolamino)titanate||Unknown||DuPont Haskell Laboratory||Results of a 28-day subchronic oral gavage toxicity study in rats|
|8EHQ-0402-15125A (PDF)||Diisopropyl ether||108-20-3||Y||American Petroleum Institute 211(b) Research Group||Preliminary results of a 4-week inhalation toxicity study in rats to evaluate immune system function|
|8EHQ-0402-15126A (PDF)||1-Butanol, titanium (4+) salt||5593-70-4||N||DuPont Haskell Laboratory||Results of an acute oral toxicity study in rats, a skin irritation study in rabbits and an eye irritation study in rabbits|
|8EHQ-0402-15127A (PDF)||2-Propanol, titanium (4+) salt||546-68-9||Y||DuPont Haskell Laboratory||Results of an acute oral toxicity study in rats and an eye irritation study in rabbits|
|8EHQ-0402-15128A (PDF)||1-Butanol, zirconium (4+) salt||1071-76-7||N||DuPont Haskell Laboratory||Results of an acute oral toxicity study in rats and a skin irritation study in rabbits|
|8EHQ-0402-15129A (PDF)||Titanium, tetrakis (2-ethyl1,3-hexanediolato)||5575-43-9||N||DuPont Haskell Laboratory||Results of an acute oral toxicity study in rats|
|8EHQ-0402-15130A (PDF)||2-Propanol||67-63-0||Y||DuPont Haskell Laboratory||Results of an acute oral toxicity study in rats|
|Titanium, bis[2-[bis(2hydroxyethyl) aminokappaN] ethanolatokappaO] bis(2propanolato)-||36673-16-2||N|
|8EHQ-0402-00373AG (PDF)||Ammonium perfluorooctanoate||3825-26-1||N||3M Company||Final report of an oral gavage 2generation reproductive toxicity study in rats|
|8EHQ-0402-14862C (PDF)||C4 crude butadiene, low butadiene content||None||American Chemistry Council||Final report of an inhalation bone marrow micronucleus test in mice|
|8EHQ-0402-14885B (PDF)||2-Phenylethyl alcohol||60-12-8||Y||Lyondell Chemical Company||Results of an acute intraperitoneal study in mice to evaluate the induction of cell proliferation by styrene metabolites|
|8EHQ-0402-15005B (PDF)||Chemical||Confidential||Y||Confidential||Results of an oral developmental toxicity study in rats|
|8EHQ-0402-15009B (PDF)||Organotin compounds||Multiple||N||Rohm and Haas Company||Response to EPA request for clarification of chemical identities and descriptions of studies|
|8EHQ-0402-15043B (PDF)||C.I. Basic Violet 11||73398-89-7||N||BASF Corporation||Chemical identity, uses and MSDS in response to EPA request|
|FYI-0402-01428A (PDF)||Compressed natural gas emissions Diesel emissions||None None||International Truck and Engine Corporation||Several reports on mutagenicity and compositional analysis|
|FYI-0402-01429A (PDF)||Propylene glycol mono-tbutyl ether||57018-52-7||N||National institute of Environmental Health Sciences||Pathology Working Group report from a 2-year carcinogenicity and chronic toxicity study in rats (exposure route not stated)|
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.
Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.