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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received January 2002

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0102-00373AA (PDF) Fluorochemicals, sulfonate-based None   3M Company Final report of a monitoring study of PFOS, FOSA, PFOA, and PFOS in biotic and abiotic phases within the Tennessee River in the vicinity of the 3M Decatur, AL Facility.
8EHQ-0102-07815 (PDF) AMS 20249 *2 Confidential   Bayer Corporation Results of an oral dietary 2-generation reproductive toxicity study in rats and information on environmental metabolism or degradation
8EHQ-0102-14692 (PDF) Oximether, substituted *2 Confidential N BASF Corporation Results of an 18-month oral dietary carcinogenicity study in mice
8EHQ-0102-15035A (PDF) Carboxamides *2 None N Bayer Corporation Results of an oral gavage developmental toxicity study in rats
8EHQ-0102-15036A (PDF) Tetrabromobisphenol A (PDF) 79-94-7 N American Chemistry Council Final report of an oral gavage developmental toxicity study in rats, an in vivo mammalian chromosome aberration test, analytical method verifications for freshwater and soil chemical determinations, and n-octanol/water partition and vapor pressure coeffic
8EHQ-0102-15037A (PDF) Decabromodiphenyl oxide 1163-19-5 N American Chemistry Council Final report of early life-stage toxicity test (rainbow trout) & Final reports of chemical biotransformation in anaerobic sediment, toxicity test to determine effects on seedling emergence of six plant species, and an activated sludge respiration inhibiti
Hexabromocyclododecane 3194-55-6 N
8EHQ-0102-15038A (PDF) Decabromodiphenyl oxide 1163-19-5 N American Chemistry Council Final report of chemical biotransformation in anaerobic sediment; Final reports of chemical biotransformation in anaerobic sediment, and effects on the survival and reproduction of earthworms
Tetrabromodiphenyl oxide 40088-47-9 N
8EHQ-0102-15039A (PDF) Carbon fibers, pitch-based Unknown N Conoco Draft report of analytical characterization of fibers in a micronized product
8EHQ-0102-15040A (PDF) Hexabromocyclododecane 3194-55-6 Y American Chemistry Council Final report of a 90-day oral gavage toxicity study in rats
8EHQ-0102-15041A (PDF) 1-Aziridinepropanoic acid, 2-((3-(1-aziridinyl)-1oxopropoxy) methyl)-2(hydroxymethyl)-1,3propanediyl ester 57116-45-7 N Bayer Corporation Summary results of an acute inhalation study in rats
8EHQ-0102-15042A (PDF) 1-Aziridinepropanoic acid, 2-methyl-, 2-ethyl-2-((3-(2methyl-1-azirdinyl)-1-oxopropoxy)methyl)-1,3propanediyl ester 64265-57-2 N Bayer Corporation Summary results of an acute inhalation study in rats
8EHQ-0102-15043A (PDF) BASONYL Red 560 Unknown   BASF Corporation Summary results of an acute inhalation study in rats
8EHQ-0102-15044A (PDF) BYI 03699 (Keto-enols) *2 Unknown   Bayer Corporation Summary results of a pilot oral gavage developmental toxicity study in rats
8EHQ-0102-15045A (PDF) BYI 08060 *2 Unknown   Bayer Corporation Summary results of a pilot oral gavage developmental toxicity study in rats
8EHQ-0102-15046A (PDF) BYH 00616 (Cyclohexadione) *2 Unknown   Bayer Corporation Summary results of a pilot oral gavage developmental toxicity study in rats
8EHQ-0102-15047A (PDF) BYI 03457 *2 Unknown   Bayer Corporation Summary results of a pilot oral gavage developmental toxicity study in rabbits
8EHQ-0102-15048A (PDF) 1-Aziridinepropanoic acid, 2-methyl-, 2-ethyl-2-((3-(2methyl-1-azirdinyl)-1-oxopropoxy)methyl)-1,3propanediyl ester 64265-57-2 N Bayer Corporation Summary results of a primary eye irritation study in rabbits
8EHQ-0102-15049A (PDF) Ethylbenzene, ethylethenylbenzene, diethenylbenzene polymer, sulfonated 69011-20-7 N Bayer Corporation Results of an eye irritation study in rabbits
8EHQ-0102-15050A (PDF) Boiled YA-CT Unknown   Bayer Corporation Results of an eye irritation study in rabbits
8EHQ-0102-15051A (PDF) Benzene, diethenyl-, polymer with ethylbenzene and ethenylethyl benzene derivative 69011-18-3 N Bayer Corporation Results of an eye irritation study in rabbits
8EHQ-0102-15052A (PDF) 1,3-Propanediamine, N,Ndimethyl-, polymer with (chloromethyl) oxirane derivative 68955-01-1 N Bayer Corporation Results of an eye irritation study in rabbits
8EHQ-0102-15053A (PDF) Oximether, substituted *2 Confidential N BASF Corporation Results of a 24-month oral dietary carcinogenicity and chronic toxicity study in rats
8EHQ-0102-15054A (PDF) Formamide 75-12-7 Y BASF Corporation Results of a micronucleus genotoxicity study in mice
8EHQ-0102-15055A (PDF) 3-Amino-5-mercapto-1,2,4-triazole 16691-43-3 N Dow Chemical Company Results of a micronucleus genotoxicity study in mice
8EHQ-0102-15056A (PDF) Chemical Confidential N Dow Chemical Company Results of a 13-week oral dietary toxicity study in dogs
8EHQ-0102-15057A (PDF) Mixture of perfluorinated phosphate surfactants 65530-72-5 N DuPont Haskell Laboratory Results of an acute inhalation toxicity study in rats
Mixture of perfluorinated phosphate surfactants 65530-71-4 N
Mixture of perfluorinated phosphate surfactants 65530-70-3 N
8EHQ-0102-15058A (PDF) Epoxy functional acrylic polymer Confidential   Confidential Results of two in vitro genotoxicity tests
8EHQ-0102-15059A (PDF) Aminochloro derivative of pyridinecarboxylic acid Confidential N Dow Chemical Company Results of an oral gavage prenatal developmental toxicity study in rats
8EHQ-0102-15060A (PDF) Quaternary ammonium chloride compound Unknown   Clariant Corporation Final report of a range-finding toxicity test in a freshwater alga
8EHQ-0102-15061A (PDF) 2-Ethylhexylchloroformate 24468-13-1 Y PPG Industries, Inc. Results of an acute inhalation study in rats
8EHQ-0102-15062A (PDF) 3,4-Dichlorophenyl isocyanate 102-36-3 N PPG Industries, Inc. Results of an acute toxicity study to assess respiratory tract sensory irritation potential in mice
8EHQ-0102-15063A (PDF) Triazolinthione *2 Unknown   Bayer Corporation Results of an oral gavage chronic toxicity study in dogs
8EHQ-0102-15064A (PDF) Ketoenols *2 Unknown   Bayer Corporation Results of an oral gavage pilot developmental toxicity study in rabbits
8EHQ-0102-15065A (PDF) Strobilurin *2 Unknown   Bayer Corporation Results of an oral dietary chronic toxicity study in dogs
8EHQ-0102-15066A (PDF) Amino, fluorooctyl derivative of siloxanes and silicones 273737-91-0 N Degussa Corporation Final reports of acute inhalation and oral toxicity studies in rats, dermal irritation and eye irritation studies in rabbits, a dermal sensitization study in guinea pigs, an in vitro mutagenicity (Ames) test, an acute toxicity test in zebrafish, and a bio
8EHQ-0102-15067A (PDF) 1,1,1,3,3Pentachloropropane 23153-23-3 N Vulcan Chemicals Results of a 2-week inhalation toxicity study in rats with a mixture of chloroalkane by-products
1,1,1,3,5,5Hexachloropentane 18993-24-3 N
1,1,3,3,5,5Hexachloropentane 60027-77-2 N
Chloroalkanes None  
8EHQ-0102-15068A (PDF) Gasoline-MTBE Mixture Condensate None N Equiva Services, LLC (PDF) Preliminary results of an inhalation developmental toxicity study in mice (summary attached)
Methyl t-butyl ether 1634-04-4 Y
8EHQ-0102-15069A (PDF) Benzamide, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening study in green algae
8EHQ-0102-15070A (PDF) Benzamide, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening study in green algae
8EHQ-0102-15071A (PDF) Pyrimidine, substituted *2 Confidential N BASF Corporation Results of an oral gavage prenatal developmental toxicity screening study in rats
8EHQ-0102-15074A (PDF) Polyester polyol Confidential N Bayer Corporation Results of an acute inhalation toxicity study in rats
8EHQ-0102-01324C (PDF) Light hydrotreated distillate (petroleum) 64742-47-8 Y ExxonMobil Corporation Updated summarized results of a 13week oral gavage toxicity study in rats, and the original final report of the same study (1991)
8EHQ-0102-01347C (PDF) Vanadium hydroxide oxide phosphate 65232-89-5 N DuPont Chemical Solutions Enterprise Results of a 90-day subchronic toxicity oral feeding study in rats
8EHQ-0102-01347D (PDF) Vanadium hydroxide oxide phosphate 65232-89-5 N DuPont Chemical Solutions Enterprise Results of a 90-day subchronic toxicity oral feeding study in rats
8EHQ-0102-14611B (PDF) Strobilurin *2 Unknown   Bayer Corporation Results of an oral feeding subchronic toxicity study in dogs
8EHQ-0102-14801C (PDF) Amido-functional siloxane None N Dow Corning Corporation Response to EPA request for information on chemical uses
8EHQ-0102-14822D (PDF) Pyrethroid insecticide, experimental *2 Confidential N Confidential Correction on chemical identity and results of a 2-week oral toxicity study in dogs
8EHQ-0102-14866C (PDF) AMS 21619 *2 Confidential   Bayer Corporation Results of an oral gavage 2-generation reproductive toxicity study in rats
8EHQ-0102-14913B (PDF) n-Vinyl carbazole 1484-13-5 N DuPont Haskell Laboratory Results of an acute dermal toxicity study in rats
8EHQ-0102-14999B (PDF) 4-Iodo-3,3,4,4-tetrafluoro1-butene 33831-83-3 N DuPont Haskell Laboratory Results of an oral gavage 28-day toxicity study in rats
8EHQ-0102-15019B (PDF) Potassium-2-(3-trifluoromethoxy-1,1,2,2,3,3hexa-fluoropropoxy)2,3,3,3-tetrafluoropropionate Unknown N 3M Company Response to EPA request for information on chemical identity
FYI-0102-01418A (PDF) Octamethylcyclotetrasiloxane 556-67-2 Y Dow Corning Corporation Final report of an in vitro metabolism study with human liver cells
FYI-0102-01419A (PDF) Octamethylcyclotetrasiloxane 556-67-2 Y Dow Corning Corporation Final report of an inhalation study to evaluate reproductive endocrine effects in female rats
FYI-0102-01420A (PDF) Hexamethyldisiloxane 107-46-0 N Dow Corning Corporation Final report of a study of in vitro effects of siloxanes on human immune cells
Decamethylcyclopentasiloxane 541-02-6 N
Octamethylcyclotetrasiloxane 556-67-2 N
FYI-0102-01421A (PDF) Octamethylcyclotetrasiloxane 556-67-2 Y Dow Corning Corporation Report of pharmakokinetic modeling of induction of liver proteins in rats following inhalation exposure
FYI-0102-01424A (PDF) Hexabromocyclododecane 3194-55-6 Y American Chemistry Council Final report of a 90-day oral gavage toxicity study in rats (converted from 8EHQ-0102-15040A)
FYI-0102-01378AI (PDF) Perfluorooctanoate, potassium salt 2795-39-3 N 3M Company Final reports of two analytical studies of human serum levels of fluorochemicals and associated biochemical parameter values
Ammonium perfluorooctanoate 3825-26-1 N

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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