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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received May 2002

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0502-13585 (PDF) Octamethylcyclotetrasiloxane 556-67-2 Y Dow Corning Corporation Final report of an inhalation 2generation reproductive toxicity and developmental neurotoxicity study in rats
8EHQ-0502-13687 (PDF) Propylene oxide 75-56-9 Y American Chemistry Council Notice that previously submitted genotoxicity and biomarker data have been published
8EHQ-0502-13706 (PDF) Cyclopropanemethanol 2516-33-8 N Eastman Chemical Company Final report of a 4-week inhalation toxicity study in rats
8EHQ-0502-15131A (PDF) Titanium, bis(2,4pentanedionatokappaO, kappaO’) bis(2propanolato) 17927-72-9 N DuPont Haskell Laboratory Results of an acute oral toxicity study in rats and an eye irritation study in rabbits
8EHQ-0502-15132A (PDF) Naphtha, petroleum, light steam-cracked, isoprene-rich 68514-39-6 Y Chevron Phillips Chemical Company LP Preliminary results of an inhalation developmental toxicity study in rats
Hydrocarbons, C5unsaturated 68956-55-8 N
8EHQ-0502-15133A (PDF) Fiber glass Unknown   Johns Manville Preliminary results of an epidemiology study of fiber glass workers
8EHQ-0502-15134A (PDF) Trisnonylphenyl phosphite 26523-78-4 Y General Electric Company Final report of an oral gavage reproductive and developmental toxicity study in rats; chemical uses
8EHQ-0502-15135A (PDF) Bentazon *2 25057-89-0 N BASF Corporation Preliminary results of an epidemiological study of workers focusing on process chemical used to produce the pesticide product
8EHQ-0502-15136A (PDF) Gasoline 86290-81-5 Y American Petroleum Institute 211(b) Research Group Results of an inhalation developmental toxicity study in mice
8EHQ-0502-15137A (PDF) Pyrolysis C5 gasoline stream 68476-55-1 Y Equistar Chemicals, LP Preliminary results of an inhalation dose range-finding study in rats for a proposed reproductive and developmental toxicity screening study
8EHQ-0502-15138A (PDF) C5 unsaturated hydrocarbons 68956-55-8 N Dow Chemical Company Preliminary results of an inhalation dose range-finding study in rats for a proposed reproductive and developmental toxicity screening study
8EHQ-0502-15139A (PDF) 2-Propanol, 1-(tertdodecylthio) 67124-09-8 Y Confidential Draft report of an oral gavage 1generation reproductive and developmental toxicity study in rats
8EHQ-0502-15140A (PDF) TKA 40252 None N Ciba Specialty Chemicals North America Final report of a skin sensitization study in guinea pigs
8EHQ-0502-15141A (PDF) 6-Methyl-5-hepten-2-one 110-93-0 N BASF Corporation Results of an oral gavage 3-month reproductive toxicity study in rats
8EHQ-0502-15142A (PDF) Ortho-xylene, substituted *2 Confidential N BASF Corporation Results of an acute oral toxicity study in rats
8EHQ-0502-15143A (PDF) Isothiazolcarboxanilide Confidential N Bayer Corporation Results of a pilot oral gavage developmental toxicity study in rabbits
8EHQ-0502-15144A (PDF) Triethyl phosphite 122-52-1 Y Bayer Corporation Results of an oral gavage reproductive and developmental toxicity screening test in rats
8EHQ-0502-15145A (PDF) 1H-Imidazole-1-ethanol, 2(hepta-decenyl)-4,5dihydro 27136-73-8 N Clariant Corporation Summary in English of an acute toxicity study in zebrafish
8EHQ-0502-15146A (PDF) Vinyl acetate 108-05-4 Y Vinyl Acetate Toxicology Group, Inc. Translation of a final report of 2-year carcinogenicity stdies administered to rats and mice in drinking water
8EHQ-0502-15147A (PDF) Vinyl acetate 108-05-4 Y Vinyl Acetate Toxicology Group, Inc. Results of two long-term oral drinking water carcinogenicity studies in rats and mice
8EHQ-0502-15148A (PDF) Ethylene oxide 75-21-8 Y American Chemistry Council Draft reports of two epidemiological studies of cancer incidence and mortality in workers
8EHQ-0502-15149A (PDF) Pyridine ketone, substituted *2 Confidential N Syngenta Crop Protection, Inc. Results of a maximum clinically tolerated dose study in dogs (route of administration and length of study not stated)
8EHQ-0502-13829D (PDF) n-Diiodoperfluoroalkanes mixture None N DuPont Haskell Laboratory Results of a 2-week inhalation toxicity study in rats
Hexadecafluoro-1,8diiodooctane 335-70-6 N
Diiodofluoro chemical 65975-18-0 N
1,6-Diiodoperfluorohexane 375-80-4 N
1,1,2,2,3,3,4,4-Octafluoro1,4-diiodobutane 375-50-8 N
8EHQ-0502-14922C (PDF) Fluorophosphate derivative (TFFH) 164298-23-1 N Applied Biosystems Draft report of an eye irritation study in rabbits and an MSDS
Fluorophosphate derivative (PyAOP) 156311-83-0 N
8EHQ-0502-15030B (PDF) Propylene oxide 75-56-9 Y American Chemistry Council Notice that previously submitted genotoxicity and biomarker data have been published
8EHQ-0502-15058B (PDF) Epoxy functional acrylic polymer Confidential   Confidential Response to EPA request for information on use and exposure; results of acute mammalian toxicity including sensitization, genotoxicity and aquatic toxicity, and biodegradation potential
8EHQ-0502-15060B (PDF) Quaternary ammonium compounds, C12-18-alkyl (hydroxy-ethyl) dimethyl, chlorides 85736-63-6 N Clariant Corporation Response to EPA request for chemical identity of test substance
8EHQ-0502-15061B (PDF) 2-Ethylhexylchloroformate 24468-13-1 Y PPG Industries, Inc. Final report of an acute inhalation toxicity study in rats
8EHQ-0502-15062B (PDF) 3,4-Dichlorophenyl isocyanate 102-36-3 N PPG Industries, Inc. Final report of an acute inhalation toxicity study in rats

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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