TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received November 2002
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|8EHQ-1102-13706 (PDF)||Cyclopropanemethanol||2516-33-8||N||Eastman Chemical Company||Response to EPA request for information on uses, exposure, and voluntary risk management, including a material safety data sheet|
|8EHQ-1102-13853B (PDF)||Quinazolinone||Confidential||N||Confidential||Results of an 18-month oral feeding carcinogenicity and chronic toxicity study in mice|
|8EHQ-1102-14415 (PDF)||Triazolinone||Confidential||N||Bayer Corporation||Identity of test chemical|
|8EHQ-1102-15222A (PDF)||Monomethyltin trichloride||993-16-8||Y||Parametrix, Inc.||Preliminary results from a micronucleus test in rats|
|8EHQ-1102-15223A (PDF)||Acrylonitrile||107-13-1||Y||Acrylonitrile Group, Inc.||Report of a clinical study of exposed workers|
|8EHQ-1102-15224A (PDF)||Distillates, petroleum, thermal cracked naphtha, and gas oil||68603-00-9||Y||American Chemistry Council||Final report of the range-finding portion of an inhalation micronucleus test in mice with a mixture of five pyrolysis C5 streams|
|Hydrocarbons, C1-4, debutanizer fraction||68527-19-5||Y|
|Hydrocarbons, C4-6, C5 rich||68479-43-7||Y|
|8EHQ-1102-15225A (PDF)||4,4'-Oxydianiline||101-80-4||Y||Dupont Haskell Laboratory||Results of an oral gavage pilot developmental toxicity study in rats; results of an oral feeding 90-day toxicity and one-generation reproductive toxicity study in rats|
|8EHQ-1102-15226A (PDF)||Pyridinecarboxamide||None||N||Confidential||Results of an oral gavage pilot developmental toxicity study in rats|
|8EHQ-1102-15227A (PDF)||CT-747-02||None||N||Cytec Industries, Inc.||Results of an intraperitoneal injection bone marrow micronucleus assay in mice, an Ames assay, and an in vitro chromosome aberration study|
|8EHQ-1102-15228A (PDF)||Ethylbenzene||100-41-4||Y||American Chemistry Council||Preliminary results of an inhalation range-finding toxicity study in rats for a 2-generation reproductive toxicity study|
|8EHQ-1102-15229A (PDF)||Triflumuron||Confidential||N||Bayer Corporation||Results of an oral developmental toxicity study in rabbits|
|8EHQ-1102-15230A (PDF)||Benzoxazione||None||N||Bayer Corporation||Results of an oral gavage developmental toxicity study in rats|
|8EHQ-1102-15231A (PDF)||1-Aziridinepropanoic acid, 2-methyl-, 2-ethyl-2-((3-(2methyl-1-azirdinyl)-1-oxopropoxy)methyl)-1,3propanediyl ester||64265-57-2||N||Bayer Corporation||Results of a micronucleus genotoxicity test in mice (route of administration not stated)|
|8EHQ-1102-15232A (PDF)||Cobalt oxide||Confidential||Bayer Corporation||Results of a 28-d oral gavage toxicity study in rats|
|8EHQ-1102-15233A (PDF)||Prothioconazole||Confidential||Bayer Corporation||Results of an acute skin irritation study in rabbits|
|8EHQ-1102-15234A (PDF)||AMS 21619||Confidential||Bayer Corporation||Results of an acute inhalation toxicity study in rats|
|8EHQ-1102-15235A (PDF)||Prothioconazole||Confidential||Bayer Corporation||Results of a skin sensitization study in guinea pigs|
|8EHQ-1102-15237A (PDF)||Chloromethoxyacetophenone||2196-99-8||N||BASF Corporation||Results of an acute toxicity study in zebrafish|
|8EHQ-1102-15240A (PDF)||Tri-(2-ethylhexyl) trimellitate||3319-31-1||Y||Confidential||Results of an oral gavage developmental toxicity study in rats|
|8EHQ-1102-15241A (PDF)||1,3-Bis(2,3-epoxypropyl)2-(2,3-epoxypropoxy) benzene||13561-08-5||N||Confidential||Final report of an in vitro chromosome aberration test|
|8EHQ-1102-15242A (PDF)||Chemical 1 None NChemical 2||None||N||Dow Chemical Company||Results of an oral gavage acute toxicity study in mice|
|8EHQ-1102-00373AI (PDF)||Perfluorohexanesulfonate, potassium salt||Unknown||N||3M Environmental Technology and Safety Services||Results of an oral gavage combined repeated dose toxicity study with reproductive and developmental toxicity screening test in rats|
|8EHQ-1102-15102B (PDF)||Ethylene oxide||75-21-8||Y||American Chemistry Council||Published Hungarian report of a genotoxicological investigation of occupationally exposed hospital nurses|
|8EHQ-1102-15151B (PDF)||Cobalt oxide||Confidential||Bayer Corporation||Results of an acute inhalation toxicity study in rats|
|8EHQ-1102-15153B (PDF)||Cobalt oxide||Confidential||Bayer Corporation||Results of a skin sensitization study in guinea pigs|
|8EHQ-1102-15189B (PDF)||Quaternary ammonium compound||Confidential||N||Ciba Specialty Chemicals North America||Response to EPA request for information on exposure and risk management|
|FYI-1102-01436A (PDF)||3,3',4,4',5Pentachlorobiphenyl||57465-28-8||N||National Institute of Environmental Health Sciences||Pathology working group report and summary pathology tables for an oral gavage carcinogenicity and chronic toxicity study in rats for toxic equivalency factor evaluation|
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.
Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.