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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received November 2002

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1102-13706 (PDF) Cyclopropanemethanol 2516-33-8 N Eastman Chemical Company Response to EPA request for information on uses, exposure, and voluntary risk management, including a material safety data sheet
8EHQ-1102-13853B (PDF) Quinazolinone Confidential N Confidential Results of an 18-month oral feeding carcinogenicity and chronic toxicity study in mice
8EHQ-1102-14415 (PDF) Triazolinone Confidential N Bayer Corporation Identity of test chemical
8EHQ-1102-15222A (PDF) Monomethyltin trichloride 993-16-8 Y Parametrix, Inc. Preliminary results from a micronucleus test in rats
8EHQ-1102-15223A (PDF) Acrylonitrile 107-13-1 Y Acrylonitrile Group, Inc. Report of a clinical study of exposed workers
8EHQ-1102-15224A (PDF) Distillates, petroleum, thermal cracked naphtha, and gas oil 68603-00-9 Y American Chemistry Council Final report of the range-finding portion of an inhalation micronucleus test in mice with a mixture of five pyrolysis C5 streams
Hydrocarbons, C1-4, debutanizer fraction 68527-19-5 Y
Hydrocarbons, C4-6, C5 rich 68479-43-7 Y
Hydrocarbons, C5-rich 68476-55-1 Y
Hydrocarbons, C5-unsaturated 68956-55-8 Y
8EHQ-1102-15225A (PDF) 4,4'-Oxydianiline 101-80-4 Y Dupont Haskell Laboratory Results of an oral gavage pilot developmental toxicity study in rats; results of an oral feeding 90-day toxicity and one-generation reproductive toxicity study in rats
8EHQ-1102-15226A (PDF) Pyridinecarboxamide None N Confidential Results of an oral gavage pilot developmental toxicity study in rats
8EHQ-1102-15227A (PDF) CT-747-02 None N Cytec Industries, Inc. Results of an intraperitoneal injection bone marrow micronucleus assay in mice, an Ames assay, and an in vitro chromosome aberration study
8EHQ-1102-15228A (PDF) Ethylbenzene 100-41-4 Y American Chemistry Council Preliminary results of an inhalation range-finding toxicity study in rats for a 2-generation reproductive toxicity study
8EHQ-1102-15229A (PDF) Triflumuron Confidential N Bayer Corporation Results of an oral developmental toxicity study in rabbits
8EHQ-1102-15230A (PDF) Benzoxazione None N Bayer Corporation Results of an oral gavage developmental toxicity study in rats
8EHQ-1102-15231A (PDF) 1-Aziridinepropanoic acid, 2-methyl-, 2-ethyl-2-((3-(2methyl-1-azirdinyl)-1-oxopropoxy)methyl)-1,3propanediyl ester 64265-57-2 N Bayer Corporation Results of a micronucleus genotoxicity test in mice (route of administration not stated)
8EHQ-1102-15232A (PDF) Cobalt oxide Confidential   Bayer Corporation Results of a 28-d oral gavage toxicity study in rats
8EHQ-1102-15233A (PDF) Prothioconazole Confidential   Bayer Corporation Results of an acute skin irritation study in rabbits
8EHQ-1102-15234A (PDF) AMS 21619 Confidential   Bayer Corporation Results of an acute inhalation toxicity study in rats
8EHQ-1102-15235A (PDF) Prothioconazole Confidential   Bayer Corporation Results of a skin sensitization study in guinea pigs
8EHQ-1102-15237A (PDF) Chloromethoxyacetophenone 2196-99-8 N BASF Corporation Results of an acute toxicity study in zebrafish
8EHQ-1102-15240A (PDF) Tri-(2-ethylhexyl) trimellitate 3319-31-1 Y Confidential Results of an oral gavage developmental toxicity study in rats
8EHQ-1102-15241A (PDF) 1,3-Bis(2,3-epoxypropyl)2-(2,3-epoxypropoxy) benzene 13561-08-5 N Confidential Final report of an in vitro chromosome aberration test
8EHQ-1102-15242A (PDF) Chemical 1 None NChemical 2 None N Dow Chemical Company Results of an oral gavage acute toxicity study in mice
8EHQ-1102-00373AI (PDF) Perfluorohexanesulfonate, potassium salt Unknown N 3M Environmental Technology and Safety Services Results of an oral gavage combined repeated dose toxicity study with reproductive and developmental toxicity screening test in rats
8EHQ-1102-15102B (PDF) Ethylene oxide 75-21-8 Y American Chemistry Council Published Hungarian report of a genotoxicological investigation of occupationally exposed hospital nurses
8EHQ-1102-15151B (PDF) Cobalt oxide Confidential   Bayer Corporation Results of an acute inhalation toxicity study in rats
8EHQ-1102-15153B (PDF) Cobalt oxide Confidential   Bayer Corporation Results of a skin sensitization study in guinea pigs
8EHQ-1102-15189B (PDF) Quaternary ammonium compound Confidential N Ciba Specialty Chemicals North America Response to EPA request for information on exposure and risk management
FYI-1102-01436A (PDF) 3,3',4,4',5Pentachlorobiphenyl 57465-28-8 N National Institute of Environmental Health Sciences Pathology working group report and summary pathology tables for an oral gavage carcinogenicity and chronic toxicity study in rats for toxic equivalency factor evaluation

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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