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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received September 2003

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0903-15403A (PDF) Fluororacrylate copolymer Confidential   Daikin America, Inc. Preliminary results of an acute inhalation toxicity study in rats
8EHQ-0903-15413A (PDF) Diethanolamine 111-42-2 Y American Chemistry Council Final report of a 90-day inhalation toxicity study in rats
8EHQ-0903-15415A (PDF) Prothioconazole *2 Unknown N Bayer Corporation Results of a 2-year oral gavage carcinogenicity study in rats
8EHQ-0903-15416A (PDF) Pyrethroid insecticide, experimental *2 Confidential N Confidential Results of a 13-week repeated dose oral feeding toxicity study in rats
8EHQ-0903-15417A (PDF) Dicyclopentadiene/ codimer concentrate 68478-10-4 Y American Chemistry Council Final report of a 48-hour oral gavage range-finding study in mice to determine dose levels for a micronucleus test
8EHQ-0903-15418A (PDF) Pyrethroid insecticide, experimental *2 Confidential   Insect Control & Research, Inc. Results of a 14-day oral feeding toxicity study in mice
8EHQ-0903-15419A (PDF) Tetramethyldisiloxane 3277-26-7 N Dow Corning Corporation Results of a skin sensitization study in guinea pigs
8EHQ-0903-15420A (PDF) 7-Oxabicyclo[4.1.0] heptane-3-carboxylic acid, methyl ester 41088-52-2 N Dow Chemical Company Results of an oral gavage 28-day toxicity study in rats
8EHQ-0903-15421A (PDF) Amylmetacresol 1300-94-3 N BASF Corporation Results of an acute toxicity study in algae
8EHQ-0903-15422A (PDF) 7-alpha-(1-Hydroxy-1,2,2 trimethyl-propyl)-6,14 endoethanotetra hydrothebain 16196-70-6 N BASF Corporation Results of an acute oral toxicity study in rats
8EHQ-0903-15423A (PDF) Octadecylamine oxadecylguanidine polyoxyethanol 70693-20-8 N Cytec Industries, Inc. Results of acute range-finding studies in green algae and daphnia with a mixture containing the chemical
8EHQ-0903-15424A (PDF) 1-Octen-3-ol 3391-86-4 N BASF Corporation Results of an acute toxicity study in zebrafish
8EHQ-0903-15425A (PDF) Pyrethroid insecticide, experimental *2 Confidential N Confidential Results of an acute inhalation toxicity study in rats
8EHQ-0903-15426A (PDF) 2,4-Dihalonicotinamide Confidential N Confidential Results of an oral gavage erythrocyte micronucleus and acute toxicity test in mice
8EHQ-0903-15427A (PDF) tert-Butanol 75-65-0 Y Lyondell Chemical Company Preliminary results of an oral gavage reproductive and developmental toxicity screening test (OECD TG 421) in rats
8EHQ-0903-00373AW (PDF) Perfluorooctane sulfonate (PFOS) 2795-39-3 N 3M Company Revision to final report of a study to determine background fluorochemical levels in rats and exposure sources
8EHQ-0903-00373AX (PDF) Perfluorohexanesulfonate, potassium salt Unknown   3M Company Final report of an oral gavage combined repeated dose toxicity study with a reproductive/developmental toxicity screening study in rats
8EHQ-0903-15247B (PDF) Zonyl7 FSP fluorosurfactant None N DuPont Haskell Laboratory Response to EPA request for information on uses, exposure, and voluntary risk management
8EHQ-0903-15262B (PDF) 1-Butanesulfonyl fluoride, 1,1,2,2,3,3,4,4 octafluoro-4-[(trifluoroethenyl) oxy] 88190-28-7 N 3M Company Final report of an oral gavage 28-day repeated dose toxicity study in rats
8EHQ-0903-15274B (PDF) Carbonyl sulfide 463-58-1 N Praxair, Inc. Follow-up letter to earlier report of a worker=s accidental chemical exposure
8EHQ-0903-15362B (PDF) Phenylacetide *2 Confidential N Syngenta Crop Protection, Inc. Response to EPA request for information on study protocol of a previously submitted study and a non-confidential generic chemical name
8EHQ-0903-15363B (PDF) Catnip essential oil None   DuPont Haskell Laboratory Response to EPA request for information on uses, exposure, and voluntary risk management
8EHQ-0903-15390B (PDF) Mixture Confidential   Confidential Response to EPA request for information on test mixture
FYI-0903-01456A (PDF) Sodium chlorate 7775-09-9 N National Institute of Environmental Health Sciences Pathology Working Group Report and Summary Pathology Tables of an oral drinking water carcinogenicity and chronic toxicity study in rats and mice
FYI-0903-01457A (PDF) 2,2',4,4',5,5'-Hexachlorobiphenyl 35065-27-1 N National Institute of Environmental Health Sciences Summary Pathology Tables of an oral gavage carcinogenicity and chronic toxicity study in rats for toxic equivalency factor evaluation
2,3,7,8-Tetrachlorodibenzo-pdioxin 1746-01-6 N
Dioxins None N
2,3,4,7,8 -Pentachlorodibenzofuran 57117-31-4 N
3,3',4,4',5- Pentachlorobiphenyl 57465-28-8 N
FYI-0903-01458A (PDF) Hexamethyldisiloxane 107-46-0 Y Dow Corning Corporation Final report of a one-week vapor inhalation study to evaluate kidney toxicity in male rats
FYI-0903-01459A (PDF) Dodecamethylcyclohexasiloxane 540-97-6 Y Dow Corning Corporation Final report of an in vitro dermal absorption study in human skin
FYI-0903-01460A (PDF) Decamethylcyclopentasiloxane 541-02-6 Y Dow Corning Corporation Final report of a vapor inhalation study of absorption, distribution, metabolism, and excretion in rats
FYI-0903-01461A (PDF) Octamethylcyclotetrasiloxane 556-67-2 Y Dow Corning Corporation Final report of a comparative inhalation metabolism study in two strains of rats
FYI-0903-01462A (PDF) 1-Butene 106-98-9 Y American Chemistry Council Final report of a pilot inhalation reproductive toxicity study in rats; final report of an inhalation combined repeated dose toxicity study with a reproductive toxicity and neurotoxicity screen in rats
Ethylbenzene 100-41-4 Y

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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