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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received May 2004

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0504-15562A (PDF)
(423 pp, 19.56MB)
Polymerization regulator, experimental Confidential N Ciba Specialty Chemicals North America Final report of a 28-d repeated dose toxicity study in rats by oral gavage.
8EHQ-0504-15563A (PDF)
(2 pp, 168K)
Cyclopropemethylamine 2516-47-4 N Eastman Chemical Company Results of a 6-d repeated dose inhalation toxicity study in rats.
8EHQ-0504-15564A (PDF)
(2 pp, 173K)
Pyrazolone Confidential   Bayer Corporation Results of a screening level developmental toxicity study in rats by oral gavage.
8EHQ-0504-15565A (PDF)
(3 pp, 289K)
Pyrazolone Confidential   Bayer Corporation Results of a range-finding developmental toxicity study in rabbits by oral gavage.
8EHQ-0504-15566A (PDF)
(2 pp, 193K)
Phenol, isopropylated, phosphate (3:1) 68937-41-7 Y Great Lakes Chemical Corporation Results of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test (OECD Test Guideline 422).
8EHQ-0504-15567A (PDF)
(2 pp, 167K)
Phenol, demthyl-, phosphate (3:1) 25155-23-1 Y Akzo Nobel Functional Chemicals LLC Results of a combined repeated dose with reproductive and developmental toxicity study in rats by oral gavage (OECD TG 422).
8EHQ-0504-15568A (PDF)
(2 pp, 119K)
Chemical *2 Confidential   Syngenta Crop Protection, Inc. Results of a 90-day dietary repeated dose toxicity study in dogs.
8EHQ-0504-15569A (PDF)
(1 pg, 96K)
Chemical *2 Confidential   Syngenta Crop Protection, Inc. Results of a local lymph node sensitization assay (species not stated).
8EHQ-0504-15570A (PDF)
(679 pp, 36.42MB)
Resin oil, low dicyclopentadiene 68477-54-3 Y Lyondell Chemical Company Draft report of a combined repeated dose toxicity study and reproductive and developmental toxicity screening test in rats by oral gavage.
8EHQ-0504-15571A (PDF)
(3 pp, 184K)
Chemical Confidential Y Confidential A preliminary report of a 28-day repeated-dose oral toxicity study in rats.
8EHQ-0504-15572A (PDF)
(3 pp, 309K)
Vinyl-tris(2-methoxyethoxy) silane 1067-53-4 Y Silicones Environmental, Health and Safety Council (SEHSC) Results of a 7-day repeated dose range-finding toxicity study in rats by oral gavage.
8EHQ-0504-15573A (PDF)
(1 pg, 103K)
1-Butanol, zirconium (4+) salt 1071-76-7 N DuPont Haskell Laboratory Results of a dermal sensitization study in guinea pigs.
8EHQ-0504-15574A (PDF)
(63 pp, 4.25MB)
Cyclohexane, 1,1'-methylenebis[4-isocyanato-, homopolymer, polyethylene glycol monmethyl ether blocked 315207-87-5 N Confidential Results of two skin sensitization studies in guinea pigs (OECD TG 406).
Benzene, 1,3'-bis(1-isocyanato-1-methylethyl)-, homopolymer polyehtylene glycol monomethyl ether blocked 197098-60-5 N
8EHQ-0504-15575A (PDF)
(1 pg, 97K)
3-Methoxy-thiophenol 15570-12-4 N BASF Corporation Results of an acute toxicity study in Daphnia magna (OECD TG 202).
8EHQ-0504-15576A (PDF)
(2 pp, 105K)
Oleylaminethozylate 26635-93-8 Y BASF Corporation Results of an acute toxicity study in Daphnia magna (OECD TG 202).
8EHQ-0504-15577A (PDF)
(1908 pp, 62.59MB)
Chemical *2 Confidential N Confidential Final report of 28-d repeated dose oral dietary toxicity study in rats; Draft report of 13-wk repeated dose oral dietary toxicity study in rats with 4-wk recovery period; and Draft report of 13-wk repeated-dose oral dietary toxicity study in mice.
8EHQ-0504-15578A (PDF)
(312 pp, 20.53MB)
Carbon fiber 7440-44-0 Y Confidential Final reports of 3-month subchronic toxicity and biopersistence inhalation studies in rats; evaluation of the biopersistence study and comparative evaluation of subchronic toxicity studies with three fiber types.
8EHQ-0504-15579A (PDF)
(1 pg, 95K)
Amide-acetal *2 Confidential N Confidential Results of a dermal sensitization study in mice.
8EHQ-0504-15609A (PDF)
(36 pp, 1.84MB)
Sulfonic acids, petroleum, Na salts 68608-26-4 Y Cytec Industries, Inc. Final report of an acute toxicity study in rainbow trout under static test conditions (OECD TG 203).
Butanol 71-36-3 Y
Hydrocarbon mixture Unknown  
Alcohol Unknown
8EHQ-0504-15082B (PDF)
(2 pp, 82K)
Hydrazine, substituted *2 Confidential N BASF Corporation Correction to test substance identity.
8EHQ-0504-15211F (PDF)
(547 pp, 22.09MB)
SP 7077 Confidential N Confidential Final reports of four female juvenal developmental toxicity studies with possible endocrine effects and results of male juvenal developmental toxicity studies in rats by oral gavage.
8EHQ-0504-15403C (PDF)
(98 pp, 4.09MB)
Fluoroalkyl acrylate copolymer Confidential   Confidential Final results of an acute inhalation study in rats (nose only).
8EHQ-0504-15509B (PDF)
(11 pp, 558K)
Fluorochemical salt Confidential N 3M Company Final report of an acute eye irritation study in rabbits.
8EHQ-0504-15524B (PDF)
(381 pp, 18.60MB)
N-(Cyanomethyl)-N-ethyl-m-toluidine 63133-74-4 Y Eastman Chemical Company Final report of a reproductive and developmental toxicity screening test in the rat by oral gavage.
8EHQ-0504-15534B (PDF)
(1 pg, 685K)
Fatty acids, C18-unsaturated, dimers, reaction products with bispehnol A-epichlorohydrin copolymer, tall-oil fatty acids, tetraethylene-pentamine and triethylene-tetramine 68459-44-9 N Confidential Response to EPA request for information on test chemical identity, exposure, uses, and risk management.
8EHQ-0504-15541B (PDF)
(28 pp, 1.43MB)
Diacetyl 431-03-8 N Crompton Corporation Final report of an acute inhalation toxicity study in rats; also, information on uses and voluntary risk management actions with workers.
8EHQ-0504-15557B (PDF)
(64 pp, 3.93MB)
Tetrakishydroxymethylphos phonium sulfate (THPS) 55566-30-8 N Cytec Industries, Inc. Final report of an acute inhalation toxicity study in rats.
8EHQ-0504-15559B (PDF)
(7 pp, 438K)
Pesticide, experimental *2 Confidential   Confidential Results of a 7-d repeated dose toxicity oral toxicity study in rats.
8EHQ-0504-15559C (PDF)
(7 pp, 416K)
Insecticide, experimental *2 Confidential N Confidential Results of an acute oral toxicity study in rats.
8EHQ-0504-15559D (PDF)
(7 pp, 447K)
Insecticide, experimental *2 Confidential N Confidential Results of a 4-hour acute inhalation toxicity study in rats.
FYI-0504-01378AS (PDF)
(13 pp, 1.03MB)
Perfluorooctanoic acid (PFOA) 335-67-1 N E.I. du Pont de Nemours and Company Three abstracts of an epidemilogical study on cancer prevalence and chemical exposure.

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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