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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received August 2005

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0805-16105A (PDF)
(16 pp, 1.19MB)
Substituted thiophene derivative* Confidential N Confidential Results of an acute inhalation and two dietary reproductive toxicity studies in rats; results of multiple oral repeated dose toxicity studies in rats and dogs.
8EHQ-0805-16106A Delayed        
8EHQ-0805-16107A (PDF)
(2 pp, 131K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16108A (PDF)
(2 pp, 130K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16109A (PDF)
(2 pp, 151K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an acute toxicity study in daphnia.
8EHQ-0805-16110A (PDF)
(2 pp, 134K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16111A (PDF)
(2 pp, 132K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16112A (PDF)
(2 pp, 130K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16113A (PDF)
(2 pp, 131K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16114A (PDF)
(2 pp, 130K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16115A (PDF)
(2 pp, 136K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16116A (PDF)
(2 pp, 140K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16117A (PDF)
(2 pp, 136K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16118A (PDF)
(298 pp, 15.45MB)
Distillates, petroleum, oxidized light 64742-98-9 Y The Lubrizol Corporation Draft final report of an oral gavage combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats; final report of a preliminary 14-day oral gavage repeated dose range-finding study in rats.
8EHQ-0805-16119A (PDF)
(2 pp, 133K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16120A (PDF)
(2 pp, 136K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16121A (PDF)
(2 pp, 143K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16122A (PDF)
(2 pp, 128K)
Substituted nitrogen-containing heterocycle (CBI)** None N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16123A (PDF)
(3 pp, 187K)
Substituted acetic acid Confidential N BASF Corporation Results of an acute toxicity study in algae.
8EHQ-0805-16124A (PDF)
(2 pp, 133K)
Substituted nitrogen-containing heterocycle (CBI)** None N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16125A (PDF)
(2 pp, 132K)
Substituted nitrogen-containing heterocycle (CBI)** None N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16126A (PDF)
(2 pp, 129K)
Substituted nitrogen-containing heterocycle (CBI)** None N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16127A (PDF)
(2 pp, 130K)
Substituted nitrogen-containing heterocycle (CBI)** None N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16128A (PDF)
(2 pp, 131K)
Substituted nitrogen-containing heterocycle ** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16129A (PDF)
(2 pp, 117K)
Substituted benzeneacetonitrile* Confidential N Syngenta Crop Protection, Inc. Results of a rabbit enucleated eye test, an acute oral toxicity study in rats and a local lymph node assay in mice.
8EHQ-0805-16130A (PDF)
(157 pp, 9.09MB)
Triphenylsulfonium/bisphenol AF complex; None N 3M Company Final reports of an acute growth inhibition study in algae, an acute toxicity study in zebrafish and an acute toxicity study in daphnia.
Reaction products of benzene, reaction products with chlorine and sulfur chloride, chlorides 109037-76-5 N
Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis 1478-61-1 N
8EHQ-0805-16131A (PDF)
(1 pg, 104K)
Sulfonated azo dye Confidential N Confidential Results of a local lymph node assay in mice.
8EHQ-0805-16132A (PDF)
(1 pg, 89K)
Chemical Confidential N The Dow Chemical Company Results of an oral 28-day repeated dose toxicity study in rats.
8EHQ-0805-16134A (PDF)
(2 pp, 155K)
Phenyl chloroformate 1885-14-9 N BASF Corporation Results of an acute inhalation toxicity study in rats.
8EHQ-0805-16135A (PDF)
(2 pp, 138K)
Substituted nitrogen-containing heterocycle*** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16136A (PDF)
(2 pp, 136K)
Substituted nitrogen-containing heterocycle*** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16137A (PDF)
(2 pp, 136K)
Substituted nitrogen-containing heterocycle*** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16138A (PDF)
(2 pp, 135K)
Substituted nitrogen-containing heterocycle*** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16139A (PDF)
(1 pg, 95K)
Substituted nitrogen-containing heterocycle*** CBI N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16140A (PDF)
(2 pp, 130K)
Substituted nitrogen-containing heterocycle*** CBI N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16141A (PDF)
(2 pp, 129K)
Substituted nitrogen-containing heterocycle*** CBI N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16142A (PDF)
(2 pp, 128K)
Substituted nitrogen-containing heterocycle*** CBI N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16143A (PDF)
(2 pp, 129K)
Substituted nitrogen-containing heterocycle*** CBI N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16144A (PDF)
(2 pp, 129K)
Substituted nitrogen-containing heterocycle*** CBI N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16145A (PDF)
(2 pp, 249K)
Octylamine hydrochloride 142-95-0 N American Chemical Council Results of a 2-week repeated dose oral gavage toxicity study in rats.
8EHQ-0805-16146A (PDF)
(2 pp, 157K)
1,2-Cyclohexane-dicarboxylic acid, dinonylester, branched and linear 474919-59-0 N BASF Corporation Results of a 24 month oral combined chronic toxicity and carcinogenicity study in rats (OECD TG 453).
8EHQ-0805-16147A (PDF)
(2 pp, 138K)
Substituted thioamide*2 CBI N BASF Corporation Results of an acute toxicity screening study in daphnia.
8EHQ-0805-16148A (PDF)
(2 pp, 141K)
Substituted nitrogen-containing heterocycle*2 CBI N BASF Corporation Results of an acute toxicity screening study in fathead minnows.
8EHQ-0805-16149A (PDF)
(2 pp, 143K)
Substituted nitrogen-containing heterocycle*2 CBI N BASF Corporation Results of an acute toxicity screening study in daphnia.
8EHQ-0805-16150A (PDF)
(4 pp, 403K)
1,1,1,3,3-Pentafluoropropane 460-73-1 N Honeywell Corporation Preliminary results of an inhalation 2-generation reproductive toxicity study in rats (OECD TG 416).
8EHQ-0805-16151B (PDF)
(2 pp, 184K)
         
8EHQ-0805-16151A (PDF)
(486 pp, 23.24MB)
Solvent Yellow 41A Confidential N Ciba Specialty Chemicals North America Final report of a 28-day repeated dose toxicity study in rats by oral gavage.
8EHQ-0805-16152A (PDF)
(1 pg, 71K)
Chemical (confidential) None N The Dow Chemical Company Results of an oral gavage acute toxicity study in mice.
8EHQ-0805-16153A (PDF)
(2 pp, 110K)
Substituted alkene (confidential) Unknown N Confidential Results of an eye irritation screening study in rabbits.
8EHQ-0805-16154A (PDF)
(2 pp, 147K)
Sodium mercaptide 1201-10-8 Y Mercaptans/ Thios Council Results of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by oral gavage (OECD TG 421).
8EHQ-0805-16155A (PDF)
(2 pp, 149K)
2-Ethylhexyl-mercaptoacetate 7659-86-1 Y Thioesters Association Results of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by oral gavage (OECD TG 421).
8EHQ-0805-16156A (PDF)
(4 pp, 227K)
t-Butyl acetate 540-88-5 N Confidential Results of a 14-day repeated dose inhalation toxicity study in mice.
8EHQ-0805-16157A (PDF)
(2 pp, 148K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16158A (PDF)
(2 pp, 148K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16159A (PDF)
(2 pp, 144K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16160A (PDF)
(2 pp, 148K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16161A (PDF)
(2 pp, 151K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16162A (PDF)
(2 pp, 155K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16163A (PDF)
(2 pp, 151K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16164A (PDF)
(2 pp, 149K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16165A (PDF)
(2 pp, 149K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16166A (PDF)
(2 pp, 150K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16167A (PDF)
(2 pp, 157K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Results of a 28-day dermal toxicity study in rats.
8EHQ-0805-16168A (PDF)
(2 pp, 176K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Preliminary results of a dietary developmental neurotoxicity study in rats.
8EHQ-0805-16169A (PDF)
(2 pp, 172K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Results of a dietary 2-generation reproductive toxicity study in rats.
8EHQ-0805-16170A (PDF)
(2 pp, 156K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Results of a 78-week dietary carcinogenicity study in mice.
8EHQ-0805-16171A (PDF)
(2 pp, 143K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Results of a skin sensitization study in guinea pigs.
8EHQ-0805-16172A (PDF)
(2 pp, 181K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Results of a 2-year dietary combined chronic toxicity and carcinogenicity study in rats.
8EHQ-0805-16173A (PDF)
(2 pp, 165K)
Substituted cyclohexane Confidential N Bayer Material Science Corporation Results of a 2-year dietary combined chronic toxicity and carcinogenicity study in rats.
8EHQ-0805-16174A (PDF)
(1 pg, 96K)
Fluoroalkyl bisphenol derivative Confidential N 3M Company Results of a local lymph node assay in mice for contact hypersensitivity.
8EHQ-0805-16175A (PDF)
(2 pp, 142K)
Diethanolamine 111-42-2 Y American Chemistry Council Preliminary results of a dermal developmental toxicity study in mice.
8EHQ-0805-16176A (PDF)
(2 pp, 174K)
Substituted benzamide Confidential N Bayer Material Science Corporation Results of an oral gavage range-finding developmental toxicity study in rabbits.
8EHQ-0805-16177A (PDF)
(2 pp, 141K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16178A (PDF)
(2 pp, 144K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16179A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16180A (PDF)
(2 pp, 143K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16181A (PDF)
(2 pp, 143K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16182A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16183A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16184A (PDF)
(2 pp, 147K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16185A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16186A (PDF)
(2 pp, 144K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16187A (PDF)
(2 pp, 144K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16188A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16189A (PDF)
(2 pp, 144K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16190A (PDF)
(2 pp, 149K)
Substituted nitrogen-containing heterocycle** Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16191A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle* Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16192A (PDF)
(2 pp, 147K)
Substituted nitrogen-containing heterocycle* Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16193A (PDF)
(2 pp, 146K)
Substituted nitrogen-containing heterocycle* Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16194A (PDF)
(2 pp, 143K)
Substituted nitrogen-containing heterocycle* Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16195A (PDF)
(2 pp, 146K)
Substituted nitrogen-containing heterocycle* Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16196A (PDF)
(2 pp, 145K)
Substituted nitrogen-containing heterocycle* Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0805-16197A (PDF)
(2 pp, 275K)
Butyl acetate 123-86-4 Y American Chemistry Council Results of an inhalation and oral range-finding toxicity study for a 2-generation reproductive toxicity study in rats.
8EHQ-0805-16198A (PDF)
(2 pp, 130K)
Halogenated oxygenated alcohol Confidential N The Dow Chemical Company Results of an acute inhalation toxicity study in rats and a dermal irritation & acute toxicity study in mice.
8EHQ-0805-16199A (PDF)
(3 pp, 277K)
Modified spinosyn Confidential N The Dow Chemical Company Results of a 90-day dietary repeated dose toxicity study in rats.
8EHQ-0805-00394F (PDF)
(2 pp, 164K)
Ammonium perfluorooctanoate 3825-26-1 N DuPont Haskell Laboratory Results of an ongoing epidemiological study in workers.
8EHQ-0805-14541B (PDF)
(1 pg, 97K)
Octylamine 111-86-4 Y BASF Corporation Results of an acute toxicity study in algae.
8EHQ-0805-15471B (PDF)
(1 pg, 79K)
Fluoxetin hydrochloride 56296-78-7   BASF Corporation Results of an acute toxicity test in algae.
8EHQ-0805-15945C (PDF)
(1 pg, 114K)
Substituted anthranilamide Confidential   Confidential Results of a dietary 28-day repeated dose toxicity study in dogs.
8EHQ-0805-16027B (PDF)
(171 pp, 7.62MB)
N-Oxidiethylene-thiocarbamoyl-N-oxydiethylene-sulfenamide 13752-51-7 Y Noveon, Inc. Final report of a dietary reproductive and developmental toxicity study in rats.
8EHQ-0805-16043C (PDF)
(1 pg, 80K)
Substituted lactone Confidential N Confidential Results of a local lymph node assay in mice.
8EHQ-0805-16044B (PDF)
(6 pp, 356K)
Methyl oxirane 75-56-9 Y American Chemistry Council Results of a 20-day repeated dose inhalation toxicity study in male mice and male rats.
8EHQ-0805-16060B (PDF)
(1 pg, 113K)
Tricresyl phosphate 1330-78-5 Y Great Lakes Chemical Corporation Results of an acute toxicity test in daphnia.
8EHQ-0805-16067B (PDF)
(171 pp, 6.42MB)
Acrylonitrile 107-13-1 Y Innovene USA LLC Final report of an acute inhalation toxicity study in rats.
8EHQ-0805-16100B (PDF)
(1 pg, 71K)
Aliphatic methacrylic monomer (CBI)* None N Confidential Results of an acute oral toxicity study in rats.
8EHQ-0805-16151B (PDF)
(2 pp, 184K)
Solvent Yellow 41A Confidential N Ciba Specialty Chemicals North America Correction to cover letter for a final report of a 28-day repeated dose toxicity study in rats by oral gavage (no changes in sanitized copy).
8EHQ-0805-16154B (PDF)
(2 pp, 147K)
Sodium mercaptide 5188-07-8 Y Mercaptans/ Thios Council Correction. It is OECD TG 422 and not 421 for the reported results of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by oral gavage.
FYI-0805-01378AW (PDF)
(216 pp, 12.33MB)
Perfluorooctanoic acid 335-67-1 N DuPont Haskell Laboratory Final report on PFOA levels in workplace air and process materials.
FYI-0805-01502B (PDF)
(7 pp, 764K)
Chemical Confidential N Keller and Heckman LLP Results of a 28-day repeated dose toxicity study inrats by oral gavage, a chronic toxicity study in zebra fish and a chronic toxicity study in daphnia.

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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