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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received December 2005

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1205-16294A (PDF)
(1 pg, 93K)
Branched perfluorobutanoyl fluoride 677-84-9 N 3M Company Results of an acute inhalation toxicity study in rats.
Linear perfluorobutanoyl fluoride 335-42-2 N
8EHQ-1205-16295A (PDF)
(1 pg, 89K)
1-Butanol, 2,2,3,4,4,4-hexafluoro-** 382-31-0 N 3M Company Results of an acute inhalation toxicity study in rats.
8EHQ-1205-16296A (PDF)
(2 pp, 131K)
Propanoic acid, propyl ester 106-36-5 N Dow Chemical Company Results of a 5-7 week repeated dose inhalation toxicity study in rats.
8EHQ-1205-16297A (PDF)
(2 pp, 155K)
Dipropylene glycol methyl ether 34590-94-8 Y American Chemistry Council Results of an in vivo metabolism study in female rats.
8EHQ-1205-16298A (PDF)
(6 pp, 453K)
Bulab 3873 Unknown   Buckman Laboratories International, Inc. Report of worker exposure (accidental) resulting in skin irritation and rash.
Bulab 3810 Unknown
Bulab 3847 Unknown
8EHQ-1205-16299A (PDF)
(2 pp, 200K)
Allylazine Confidential   Bayer CropScience Results of a 90-day toxicity study in rats following dietary administration.
8EHQ-1205-16300A (PDF)
(2 pp, 230K)
Reverse sulfamide Confidential   Bayer CropScience Results of an oral gavage developmental toxicity study in rabbits.
8EHQ-1205-16301A (PDF)
(1 pg, 125K)
N,N-Dimethylacetamide 127-19-5 Y Confidential Results of an acute oral toxicity study in rats and an acute eye irritation study in rabbits.
N,N-Diethylethanolamine *3 100-37-8 Y
Sulfamic acid *3 5329-14-6 N
8EHQ-1205-16302A (PDF)
(1 pg, 53K)
Hexaneperoxoicacid, 3,5,5-trimethyl-, 1,1-dimethyethyl ester 13122-18-4 N Arkema Inc. Results of a growth inhibition test in algae.
8EHQ-1205-16303A (PDF)
(1 pg, 3MB)
Chemical* Confidential N Ciba Specialty Chemicals North America Translation of a 52-week repeated dose oral toxicity study in rats.
8EHQ-1205-16304A (PDF)
(2 pp, 83K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16305A (PDF)
(2 pp, 81K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16306A (PDF)
(2 pp, 85K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16307A (PDF)
(2 pp, 84K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16308A (PDF)
(2 pp, 85K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16309A (PDF)
(2 pp, 83K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16310A (PDF)
(2 pp, 83K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16311A (PDF)
(2 pp, 82K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16312A (PDF)
(2 pp, 81K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16313A (PDF)
(2 pp, 81K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16314A (PDF)
(2 pp, 82K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16315A (PDF)
(2 pp, 84K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16316A (PDF)
(2 pp, 84K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16317A (PDF)
(2 pp, 83K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16318A (PDF)
(2 pp, 83K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16319A (PDF)
(2 pp, 88K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16320A (PDF)
(2 pp, 82K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16321A (PDF)
(2 pp, 84K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-1205-16322A (PDF)
(10 pp, 390K)
Bufloc 5378 Unknown   Buckman Laboratories International, Inc. Report on adverse health effects following workplace exposure to Bufloc 5378; Report of a fish kill following accidental release of Busperse 293 and Busan 1009 to a stream.
Busperse 293 Unknown
Busan 1009 *2 Unknown
8EHQ-1205-16323A (PDF)
(2 pp, 91k)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in daphnia.
8EHQ-1205-16324A (PDF)
(2 pp, 89K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in daphnia.
8EHQ-1205-16325A (PDF)
(2 pp, 95K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in fathead minnows.
8EHQ-1205-16326A (PDF)
(2 pp, 94K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in daphnia.
8EHQ-1205-16327A (PDF)
(1 pg, 61K)
Chemical Confidential N Syngenta Crop Protection, Inc. Results of a 28-day oral toxicity study in rats.
8EHQ-1205-16328A (PDF)
(1 pg, 60K)
Acetic acid ethyl ester, substituted Confidential   Syngenta Crop Protection, Inc. Results of a 90-day dietary toxicity study in rats.
8EHQ-1205-16329A (PDF)
(2 pp, 104K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in daphnia.
8EHQ-1205-16330A (PDF)
(3 pp, 133K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of a 2-generation reproductive toxicity study in rats.
8EHQ-1205-16331A (PDF)
(2 pp, 87K)
Amide, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in daphnia.
8EHQ-1205-16332A (PDF)
(2 pp, 90K)
Amide, substituted *2 Confidential N BASF Corporation Results of an acute toxicity screening test in fathead minnows.
8EHQ-1205-16333A (PDF)
(1 pg, 64K)
Nitrobenzene, substituted Confidential   Syngenta Crop Protection, Inc. Results of a 90-day dietary toxicity study in rats.
8EHQ-1205-16334A (PDF)
(1 pg, 66K)
Thiocarbamate ester, substituted Confidential   Syngenta Crop Protection, Inc. Results of pharmacology studies in dogs and rats, a subchronic neurotoxicity study in rats and a one-year chronic toxicity study in dogs (routes of administration not stated).
8EHQ-1205-16335A (PDF)
(1 pg, 83K)
Magenta ink* Confidential N Confidential Results of dermal sensitization study in female mice.
8EHQ-1205-16336A (PDF)
(1 pg, 73K)
Cyan ink* Confidential N Confidential Results of dermal sensitization study in female mice.
8EHQ-1205-16337A (PDF)
(1 pg, 77K)
Light cyan ink* Confidential N Confidential Results of dermal sensitization study in female mice.
8EHQ-1205-16338A (PDF)
(669 pp, 15.7MB)
Chemical Confidential   Confidential Draft report of a dietary one-generation reproductive toxicity study in rats.
8EHQ-1205-16339A (PDF)
(2 pp, 106K)
Propargyl alcohol 107-19-7 Y BASF Corporation Results of a reproductive and developmental toxicity screening test in rats by oral gavage (OECD TG 421).
8EHQ-1205-16340A (PDF)
(2 pp, 111K)
2-Butene-1,4-diol *3 110-64-5 Y BASF Corporation Results of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by oral gavage (OECD TG 422).
8EHQ-1205-16341A (PDF)
(2 pp, 99K)
Pyrasulfatole Confidential   Bayer CropScience Results of an acute oral neurotoxicity screening study in rats.
8EHQ-1205-00373BQ (PDF)
(743 pp, 22.11MB)
Perfluorooctane-sulfonyl fluoride 307-35-7 Y 3M Company Final report of a 13-week inhalation toxicity study in rats.
8EHQ-1205-00373BR (PDF)
(20 pp, 1.59MB)
Perfluorooctane-sulfonic acid, potassium salt 2795-39-3 N 3M Company Final report of a human blood serum monitoring study.
8EHQ-1205-00374F (PDF)
(20 pp, 1.59MB)
Ammonium perfluorooctanoate 3825-26-1 N 3M Company Final report of a human blood serum monitoring study.
8EHQ-1205-00394I (PDF)
(20 pp, 1.57MB)
Ammonium perfluorooctanoate 3825-26-1 N 3M Company Final report of a human blood serum monitoring study.
8EHQ-1205-15167G (PDF)
(2 pp, 138K)
Aminoethylethanolamine *3 111-41-1 Y Ethyleneamines Product Stewardship Discussion Group Results of an enhanced reproductive and developmental toxicity study in rats by oral gavage (OECD TG 421).
8EHQ-1205-15181F (PDF)
(1 pg, 70K)
Substituted anthranilamide Confidential N Confidential Results of an acute oral toxicity study in rats.
8EHQ-1205-15182F (PDF)
(1 pg, 78K)
Substituted anthranilamide Confidential N Confidential Results of an acute oral toxicity study in rats.
8EHQ-1205-15876B (PDF)
(3 pp, 120K)
Pyridine derivative, halogenated Confidential   The Dow Chemical Company Results of an 18-month repeated dose dietary toxicity study in mice.
8EHQ-1205-16012D (PDF)
(1 pg, 64K)
Atplus7 UCL 1007 Confidential   Confidential Response to EPA request for information on the chemical identities of the tested mixture.
8EHQ-1205-16012E (PDF)
(7 pp, 318K)
Atplus7 UCL 1007 Confidential   Confidential Response to EPA request for information on the chemical identities of the tested mixture and risk management actions; Material Safety Data Sheet.
8EHQ-1205-16043E (PDF)
(1 pg, 82K)
Substituted lactone**** Confidential N Confidential Response to EPA request for information on commercial status of chemical, uses, exposure and voluntary risk management actions.
8EHQ-1205-16065B (PDF)
(520 pp, 12.7MB)
3-(Triethoxysilyl)-propanenitrile 919-31-3 Y Silicones Environmental, Health and Safety Council North America Final report of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by oral gavage.
8EHQ-1205-16201B (PDF)
(124 pp, 4.34MB)
Chemical Confidential   Albemarle Corporation Final report of an in vitro mouse lymphoma cell forward mutation assay and final report of an in vitro cell transformation assay in Syrian hamster embryo cells.
8EHQ-1205-16253B (PDF)
(184 pp, 6.35MB)
Tetrahydrofuran****** 109-99-9 Y Lyondell Chemical Company Final report of an in vitro percutaneous absorption study using human cadaver skin.
8EHQ-1205-16295B (PDF)
(9 pp, 289K)
1-Butanol, 2,2,3,4,4,4-hexafluoro-* 382-31-0 N 3M Company Final report of an acute inhalation toxicity study in rats showing neurological effects.
FYI-1205-01503A (PDF)
(176 pp, 6.22MB)
Neodecanoic acid, ethenyl ester 51000-52-3 Y Hexion Specialty Chemicals, Inc Final report of a combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by oral gavage (OECD TG 422).

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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