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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received January 2005

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0105-15895A (PDF)
(2 pp, 179K)
Substituted heterocycle*** Confidential N BASF Corporation Results of an acute toxicity screening test in fathead minnows.
8EHQ-0105-15896A (PDF)
(2 pp, 172K)
Substituted heterocycle** Confidential N BASF Corporation Results of an acute toxicity screening test in fathead minnows.
8EHQ-0105-15897A (PDF)
(2 pp, 167K)
Substituted heterocycle** Confidential N BASF Corporation Results of an acute toxicity screening test in fathead minnows.
8EHQ-0105-15898A (PDF)
(32 pp, 2.81MB)
Furfural 98-01-1 Y toXcel LLC Draft report of a 21-day study to determine adverse reproductive effects in daphnia.
8EHQ-0105-15899A (PDF)
(32 pp, 2.29MB)
cis-2-Pentenenitrile 25899-50-7 Y toXcel LLC Final report of an in vitro mammalian chromosome aberration test in Chinese Hamster Ovary cells.
8EHQ-0105-15900A (PDF)
(3 pp, 133K)
Chemical Confidential   Confidential Results of Local Lymph Node Assay in mice to test for sensitization potential.
8EHQ-0105-15901A (PDF)
(2 pp, 137K)
Substituted acetic acid ethyl ester Confidential   Syngenta Crop Protection, Inc. Results of a 28-day dietary toxicity study in rats.
8EHQ-0105-15902A (PDF)
(1 pg, 98K)
Substituted thiazole Confidential   Syngenta Crop Protection, Inc. Results of an acute toxicity study in rats (route of administration not stated).
8EHQ-0105-15903A (PDF)
(1 pg, 117K)
2-Methyl-8-hydroxyquinoline 826-81-3 N National Starch and Chemical Company Results of an in vitro mutagenicity assay with Salmonella and E. coli according to OECD TG 471.
8EHQ-0105-15904A (PDF)
(161 pp, 5.44MB)
Triphenylsulfonium/bisphenol AF complex None N 3M Corporation Final report of a 28-day oral gavage toxicity study in rats.
Benzene, reaction products with chlorine and sulfur chloride(S2Cl2), chlorides 109037-76-5 N
Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl) ethylidene]bis- 1478-61-1 N
8EHQ-0105-15905A (PDF)
(1 pg, 110K)
Ethylene glycol 107-21-1 Y American Chemistry Council Preliminary results of a 1-year toxicity study in male rats (route of administration not stated).
8EHQ-0105-15906A (PDF)
(1 pg, 105K)
Carbamothioic acid, dipropyl-, S-(phenylmethyl) ester 52888-80-9 N Syngenta Crop Protection, Inc. Results of a maternal toxicity study in rabbits (route of administration not stated).
8EHQ-0105-15907A (PDF)
(2 pp, 151K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15908A (PDF)
(2 pp, 153K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15909A (PDF)
(2 pp, 152K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15910A (PDF)
(2 pp, 155K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15911A (PDF)
(2 pp, 156K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15912A (PDF)
(2 pp, 154K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15913A (PDF)
(2 pp, 158K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15914A (PDF)
(2 pp, 201K)
1-Butylimidazole 4316-42-1 N BASF Corporation Results of an acute inhalation toxicity study in rats.
8EHQ-0105-15915A (PDF)
(2 pp, 151K)
Substituted heterocycle* Confidential   BASF Corporation Results of an acute toxicity study in rainbow trout.
8EHQ-0105-15916A (PDF)
(2 pp, 160K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15917A (PDF)
(2 pp, 164K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15918A (PDF)
(2 pp, 160K)
Substituted heterocycle* Confidential   BASF Corporation Results of an in vivo micronucleus screening test in mice.
8EHQ-0105-15919A (PDF)
(2 pp, 156K)
Substituted heterocycle* Confidential   BASF Corporation Results of acute toxicity studies in daphnia and algae.
8EHQ-0105-15920A (PDF)
(2 pp, 146K)
Oxygenated aliphatic diene Confidential   The Dow Chemical Company Results of a combined repeated dose (28 days for males and 7 weeks for females) toxicity study with reproductive and developmental toxicity screening test in rats by inhalation.
8EHQ-0105-15921A (PDF)
(2 pp, 157K)
Hydrogenated bisphenol A-bisglycidyl ether 13410-58-7 N BASF Corporation Results of a mutagenicity test in Salmonella and E. coli bacteria.
8EHQ-0105-15922A (PDF)
(1 pg, 114K)
** Urea, N'-(3,4-dichlorophenyl)-
N,N-dimethyl;
330-54-1 Y Confidential Results of an in vivo micronucleus test in mice.
** 1,3,5-Triazine-2,4
(1H,3H)-dione, 3-cyclohexyl-6-(dimethyl
-amino)-1-methyl-
51235-04-2 Y
8EHQ-0105-15923A (PDF)
(2 pp, 198K)
Isophorondiisocyanate 4098-71-9 Y Bayer Material Science Corporation Results of a developmental toxicity study in rats by inhalation.
8EHQ-0105-00394C (PDF)
(2 pp, 173K)
Ammonium perfluorooctanoate 3825-26-1 N DuPont Haskell Laboratory Results of blood and urine monitoring comparing employees exposed to PFOA and employees not exposed to PFOA.
8EHQ-0105-14447B (PDF)
(98 pp, 1.64MB)
1,3-Butadiene 106-99-0 Y International Institute of Synthetic Rubber Producers, Inc. Final report of worker exposure estimates at a synthetic rubber plant, which is part of a larger cohort mortality study.
8EHQ-0105-15412B (PDF)
(3 pp, 308K)
1-Decanol,3,3,4,4,5,5,6,6,7,7, 8,8,9,9,10,10,10- heptadecafluoro- 678-39-7 N DuPont Haskell Laboratory Results of oral and dermal absorption, distibution, metabolism and elimination (ADME) studies in rats; results of in vitro metabolism experiments using human and rat hepatocytes.
8EHQ-0105-15578C (PDF)
(4 pp, 277K)
Carbon fiber 7440-44-0 Y ANA Trading Corp., U.S.A. Response to 12/27/04 EPA request to the US importer on commercial status of the carbon fiber material.
8EHQ-0105-15580B (PDF)
(311 pp, 18.85MB)
2-Amino-2-methyl-1-propanol, hydrochloride 3207-12-3 N The Dow Chemical Company Final report of an oral dietary reproductive and developmental toxicity screening test in rats.
8EHQ-0105-15585B (PDF)
(5 pp, 515K)
Furfural 98-01-1 Y toXcel - Toxicology & Regulatory Affairs Summarized final results of a 28-day repeated dose dermal toxicity study in rats.
8EHQ-0105-15671B (PDF)
(1 pg, 105K)
Chemical Confidential N 3M Corporation Response to request for information on chemical identity.
8EHQ-0105-15856 (PDF)
(174 pp, 12.41MB)
Perfluorooctanoic acid (and telomers) 335-67-1 N Patton Boggs L.L.P. Information on analytical procedures and environmental fate/monitoring.
FYI-0105-01484A Pyrolysis C5 68476-55-1 Y American Chemistry Council Final reports and robust summaries of a bacterial reverse mutation test, in vivo mouse micronucleus test, algal growth inhibition assay, acute toxicity study in daphnia, acute toxicity study in rainbow trout, biodegradation study, dose range finding study in rats by inhalation, repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by inhalation, chemical identification and determination of chemical stability, and physiochemical properties.
FYI-0105-01485A 2-Methyl-2-butene 513-35-9 Y American Chemistry Council Final reports and robust summaries of an acute toxicity study in daphnia, algal growth inhibition assay, dose range finding study in rats by inhalation, chemical identification and determination of purity, biodegradation study, acute toxicity study in rainbow trout, 4-week repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by inhalation, and 4-week repeated dose toxicity study in rats by oral gavage (with Raloxifene - CAS No. unknown).
Raloxifene Unknown
FYI-0105-01486A Residues, petroleum, steam-cracked light; 68513-69-9 Y American Chemistry Council Final reports and robust summaries of acute toxicity studies in daphnia, acute toxicity studies in fish, algal growth inhibition tests and ready biodegradability studies for heavy pyrolysis fuel oil and pyrolysis C10+ fuel oil and final reports and robust summaries of an acute toxicity study in daphnia, acute toxicity study in fish, algal growth inhibition test and ready biodegradability study for heavy pyrolysis fuel oil.
Clarified oils, petrol-eum, catalytic cracked 64741-62-4 Y
Fuel oil, pyrolysis 69013-21-4 Y
Petroleum 8002-05-9 Y
Hydrocarbons, ethylene-manufactured by-product distillation residues 68921-67-5 Y
FYI-0105-01487A Dicyclopentadiene/codimer concentrate 68478-10-4 Y American Chemistry Council Final reports and robust summaries of an algal growth inhibition test, ready biodegradability test, acute immobilization test in daphnia and acute toxicity study in fish.
FYI-0105-01488A Hydrotreated C5s 68602-79-9 Y American Chemistry Council Final reports & robust summaries of a dose range finding study in rats by inhalation, in vivo mouse micronucleus test, physiochemical properties, chemical identification and determination of chemical stability, repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by inhalation, acute toxicity study in rainbow trout, bacterial reverse mutation test, algal growth inhibition assay, assessment of biodegradability study and acute toxicity study in daphnia.
FYI-0105-01489A Isoprene 78-79-5 Y American Chemistry Council Final reports of a repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats by inhalation, acute toxicity study in daphnia, acute toxicity study in rainbow trout, algal growth inhibition assay, assessment of biodegradability study and chemical identification and determination of chemical purity.
FYI-0105-01490A (PDF)
(8 pp, 1.49MB)
** 3,4,4'-Trichlorocarbanilide 101-20-2 Y Johns Hopkins Bloomberg School of Public Health Published report of environmental contamination and fate in US water bodies.

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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