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Section 8(e) Substantial Risk Notifications and FYI Submissions Received December 2006

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1206-16663A (PDF)
(7 pp, 6.1MB)
Perfluorooctanoic acid 335-67-1 N DuPont Haskell Laboratory Updated results of PFOA serum sampling in workers at the DuPont Chambers Works facility in NJ.
8EHQ-1206-16664A (PDF)
(6 pp, 2.7MB)
Perfluorooctanoic acid 335-67-1 N DuPont Haskell Laboratory Results of PFOA serum sampling in workers at the DuPont Spruance facility in VA.
8EHQ-1206-16665A (PDF)
(1 pg, 646K)
5-Chloro-3-methyl-4-nitro­1H-pyrazole 6814-58-0 N AgroSource, Inc Results of an acute oral toxicity study in rats (up and down procedure).
8EHQ-1206-16666A (PDF)
(1 pg, 481K)
Confidential Confidential   Confidential Results of a primary eye irritation test in rabbits.
8EHQ-1206-16667A (PDF)
(5 pp, 2.6MB)
Oxetane, 3-methyl-3­[(2,2,2-trifluoro-ethoxy) methyl]­ 156294-54-1   OMNOVA Solutions, Inc Preliminary results of an acute oral toxicity study in rats.
8EHQ-1206-16668A (PDF)
(4 pp, 2MB)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of testing of acute effects on honeybees.
8EHQ-1206-16669A (PDF)
(4 pp, 2MB)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of testing of acute effect on honeybees.
8EHQ-1206-16671A (PDF)
(1 pg, 613K)
Pyridine derivative, substituted Confidential   Syngenta Crop Protection, Inc. Results of an aquatic toxicity study with Lemna.
8EHQ-1206-16672A (PDF)
(3 pp, 1.7MB)
n-Hexylchloroformate 6092-54-2 N BASF Corporation Results of an acute inhalation (vapor) study in rats.
8EHQ-1206-16673A (PDF)
(3 pp, 1.7MB)
Nitrogen-containing heterocycles, substituted *2 Confidential   BASF Corporation Results of a screening test on acute toxcity in fathead minnow.
8EHQ-1206-16674A (PDF)
(3 pp, 1.8MB)
Nitrogen-containing heterocycles, substituted *2 Confidential   BASF Corporation Results of a screening test on acute toxicity in fathead minnow.
8EHQ-1206-16675A (PDF)
(9 pp, 5.5MB)
Confidential Confidential   Confidential Summary report of an oncogenicity 18­month feeding study in mice
8EHQ-1206-16676A (PDF)
(1 pg, 486K)
Polyalkylacrylate copolymer Confidential   Confidential Results of an acute oral toxicity study in rats.
8EHQ-1206-16677A (PDF)
(21 pp, 9.8MB)
Tetramethylammonium carbonate 58345-96-3 N Moses Lake Industries, Inc. Final report of an acute dermal toxicity study in rabbits.
8EHQ-1206-16678A (PDF)
(2 pp, 933K)
Sulfonyl-aminocarbonyl triazolinone Confidential   Bayer CropScience LP Results of an acute inhalation study in rats.
8EHQ-1206-16679A (PDF)
(2 pp, 1.4MB)
Confidential Confidential   Lubrizol Corporation Preliminary results of acute aquatic toxicity studies.
8EHQ-1206-16680A (PDF)
(42 pp, 18.7MB)
Diisobutylene 25167-70-8 Y Lyondell Chemical Company Results of an acute toxicity test with fathead minnows.
8EHQ-1206-16681A (PDF)
(7 pp, 6.1MB)
Agrotain None   Agrotain International, LLC Allegation/Incident report following exposure to commercial product, Agrotain.
8EHQ-1206-16682A (PDF)
(3 pp, 1.7MB)
Hydrazone, substituted *2 Confidential   BASF Corporation Results of an acute contact and oral toxicity study on honeybees.
8EHQ-1206-16683A (PDF)
(3 pp, 2MB)
Confidential Confidential   Confidential Results of a local lymph node assay in mice.
8EHQ-1206-16684A (PDF)
(3 pp, 2MB)
Confidential Confidential   Confidential Results of a local lymph node assay in mice.
8EHQ-1206-16685A (PDF)
(2 pp, 1.2MB)
Nitrogen-containing heterocycle, substituted *2 Confidential   BASF Corporation Results of an acute toxicity study in fathead minnow.
8EHQ-1206-16686A (PDF)
(2 pp, 1.1MB)
Nitrogen-containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a screening test on acute toxicity in daphnia.
8EHQ-1206-16707A (PDF)
(2 pp, 1.3MB)
Cobalt naphthenate *3 61789-51-3 Y Synthetic Organic Chemical Manufacturers Association (SOCMA) Results of an in vitro mammalian chromosome aberration test in Chinese hamster ovary cells and a combined repeated dose toxicity study with the reproductive/developmental toxicity screening in rats.
8EHQ-1206-16708A (PDF)
(5 pp, 3MB)
2,2,4,4-Tetramethyl-1,3­cyclobutanediol 3010-96-6 N Eastman Chemical Company Final report of a 28-day repeated-dose oral gavage toxicity study in rats.
8EHQ-1206-15135D
(10 pp, 10.51MB)
Benzothiadiazin herbicide None   BASF Corporation Supplemental information of publication titled "Investigation of Cancer Occurrences Associated with an Herbicide Manufacturing Facility".
8EHQ-1206-15820C (PDF)
(1 pg, 58K)
Polyethylbenzene bottoms stream 689787-42-8 N American Chemistry Council Ethylbenzene Panel Final reports for a reproduction/ developmental toxicity dose-range finding study in rats and a combined 28-day repeated dose oral toxicity study with the reproductive/developmental toxicity screening test in rats.
Polyethylbenzene bottoms stream 689787-42-8 Final report of two studies: a reproductive/ developmental toxicity range-finding study in rats and a combined 28-day repeated-dose oral toxicity study with reproductive/ developmental toxicity screening in rats.
8EHQ-1206-16054B (PDF)
(3 pp, 4.64MB)
Polyethylbenzene bottoms stream 689787-42-8 N American Chemistry Council Ethylbenzene Panel Final reports for a reproduction/ developmental toxicity dose-range finding study in rats and a combined 28-day repeated dose oral toxicity study with the reproductive/developmental toxicity screening test in rats.
8EHQ-1206-16150B (PDF)
(1,001 pp, 29.7MB)
1,1,1,3,3­Pentafluoropropane 460-73-1 N Honeywell Corporation Final reports of a two-generation inhalation toxicity study in rats
8EHQ-1206-16202D (PDF)
(12 pp, 10.3MB)
Methylene diphenyl diisocyanate 9016-87-9   American Chemistry Council Diisocyanates Panel Reports on "Examination of three cases with acute and chronic symptoms caused by exposure to MDI" and "Neuropsychological toxicology of methylene diphenyl diisocyanate: a report of five cases".
8EHQ-1206-16488B (PDF)
(3 pp, 442K)
Polyethylbenzene bottoms stream 689787-42-8   American Chemistry Council Ethylbenzene Panel Final reports of four studies: toxicity to green algae, acute toxicity to Daphnia magna, acute toxicity to fathead minnow, and ready biodegradation
8EHQ-1206-16523B (PDF)
(58 pp, 21.3MB)
Glycol ether PM-250 None   Lyondell Chemical Company Final report on an acute oral toxicity study in rats (up and down procedure).
8EHQ-1206-16525E (PDF)
(5 pp, 1.87MB)
Isopropylmorpholine 1004-14-4 and 1331-24­4 N 3M Company Amendement to Local Lymph Node Assay in mice.
8EHQ-1206-16525F (PDF)
(192 pp, 5.53MB)
Isopropylmorpholine *1 1004-14-4 and 1331-24­4 N 3M Company Final report of a 28-day repeated dose oral toxicity study in rats.
8EHQ-1206-16622B (PDF)
(5 pp, 3.8MB)
n-Butyl acetate *3 123-86-4 Y American Chemistry Council Oxo Process Panel Interim results of a two-generation inhalation reproductive toxicity study in rats.
8EHQ-1206-16639B (PDF)
(2 pp, 979K)
None None   DuPont Haskell Laboratory Correction to worker location in submission dated November 3, 2006 (8EHQ-06-16639).
FYI-1206-01539A (PDF)
(3 pp, 1.7MB)
Perfluorooctanoic acid 335-67-1 N Ahlstrom, Windsor, Locks LLC Results of blood tests from employees concerned about the processing of fabrics containing fluoropolymers.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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