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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received May 2006

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0506-16452A Perfluorocarboxylate salt Confidential   Confidential Results of two 2-week oral gavage range-finding studies in rats for a 90-day study
8EHQ-0506-16453A Nitrogen-containing heterocycles, substituted *2 Confidential N BASF Corporation Results of four in vivo mouse micronucleus screening tests
8EHQ-0506-16454A Benzeneacetonitrile, 2-methyl-.alpha.-[5-[[[(4-methylphenyl) sulfonyl]oxy]imino]-2(5H)-thienylidene]- 219651-32-8 N Ciba Specialty Chemicals North America Final report of a local lymph node assay in mice.
8EHQ-0506-16455A 4-Acetoxystyrene 2628-16-2 N DuPont Haskell Laboratory Results of an acute inhalation study in rats
8EHQ-0506-16457A Copper hydroxide *2,*3 20427-59-2 N DuPont Haskell Laboratory Results of an acute inhalation study in rats
Cymoxanil *2 57966-95-7 N
8EHQ-0506-16458A Benzenamine, N-phenyl-, styrenated 68442-68-2 Y American Chemistry Council Results of an oral gavage combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats
8EHQ-0506-16459A Ammonium tetrachloropalladate (II) 13820-40-1 N Johnson Matthey, Inc. Report of an adverse effect of ocupational asthma Report of an adverse effect of occupational asthma
Ammonium hexachloroiridate (III) 15752-05-3 N
Ammonium hexachloroiridate (IV) 16940-92-4 N
Sodium hexachlororhodate (III) 14972-70-4 N
8EHQ-0506-16460A Perfluorooctanoic acid (PFOA) 335-67-1 N E.I. du Pont de Nemours and Company Report of environmental monitoring in municipal well water
8EHQ-0506-16461A Perfluorochemicals, sulfonate-based and carboxylic-based None N DuPont Haskell Laboratory Results of environmental monitoring of arctic biota
8EHQ-0506-16462A Halogenated aryl oxy amide Confidential   Dow Chemical Company Results of a 4-week repeated dose oral dietary toxicity study in rats, a 4-week repeated-dose oral dietary toxicity study in mice, an oral dietary reproductive toxicity study in rats, and a 2-stage oral gavage developmental toxicity study rats
8EHQ-0506-16463A 2-Propanethiol, 2-methyl 75-66-1 Y Mercaptans/Thiols Council Preliminary results of a oral gavage combined repeated dose toxicity study with a reproductive and developmental toxicity screening test in rats
8EHQ-0506-16464A Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of a 28-day repeated dose dermal toxicity study in rats.
8EHQ-0506-16465A (PDF)
(2 pp, 27K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of a 7-day toxicity study in algae.
8EHQ-0506-16466A (PDF)
(2 pp, 26K)
Nitrogen-containing heterocycle, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in green algae.
8EHQ-0506-16467A (PDF)
(1 pg, 17K)
Chemical Confidential   Syngenta Crop Protection, Inc. Results of a in vivo micronucleus study in male mice.
8EHQ-0506-16468A (PDF)
(1 pg, 17K)
Tetrabutylphosphonium-
1,1,2,3,3,3-
hexafluropropanesulfonate
Unknown N DuPont Haskell Laboratory Results of an acute oral gavage toxicity study in rats. LD50 determined by up-and-down method.
8EHQ-0506-00373BT Perfluorochemicals, sulfonate-based and carboxylic-based None   3M Company Final Consent Agreement and Final Order of a document self-audit along with cover letters submitted to TSCA 8(e) Docket as part of the Consent Agreement.
8EHQ-0506-00394L Perfluorooctanoic acid (PFOA) 335-67-1 N DuPont Haskell Laboratory Results of an epidemiological study of serum total cholesterol in workers
8EHQ-0506-15287C Chemical Confidential   Confidential Results of a combined carcinogenicity and chronic toxicity study by dietary administration to rats for 104 weeks
8EHQ-0506-16010E (PDF)
(4 pp, 58K)
Benzenamine, N-phenyl-, reaction products with isobutylene and 2,4,4-trimethylpentene 84378-08-3 N American Chemistry Council Amended pages to final report of an oral gavage combined repeat dose and reproduction/developmental toxicity study in rats
8EHQ-0506-16013B Fluoroalkoxyfluoroalkane Confidential   3M Company Final report of a 5-day inhalation toxicity study in rats
8EHQ-0506-16228B Alkyl ammonium modified phenol salt *1 Confidential   Confidential Response to EPA request for information on chemical identity, commercial status, uses, other available exposure information, and voluntary risk management actions
8EHQ-0506-16301B Mixture, proprietary None   Confidential Response to EPA request for information; updated Material Safety Data Sheet
8EHQ-0506-16359B (PDF)
(17 pp, 177K)
2-Naphthol, ethoxylated 35545-57-4 N Noveon, Inc. Final report of an acute oral gavage toxicity study in rats.
8EHQ-0506-16390B Chemical *1 197447-16-8 N Confidential Two final reports of acute dermal toxicity studies in rats
FYI-0506-01504A (PDF)
(2 pp, 27K)
Organic solvents None   National Paint & Coatings Association (NPCA) Abstract of an epidemiological study of risks of reproductive disorders and birth defects in offspring of male painters with potential high exposure to organic solvents.

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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