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Section 8(e) Substantial Risk Notifications and FYI Submissions Received December 2007

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1207-17006A (PDF)
(4 pp, 141K)
Confidential Confidential   Confidential Results of a 28-day oral repeated-dose toxicity study in rats.
8EHQ-1207-17007A (PDF)
(1 pg, 49K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results from a dose range-finding prenatal developmental toxicity study in rabbits.
8EHQ-1207-17008A (PDF)
(1 pg, 73K)
Acrylamide 79-06-1 Y Ciba Specialty Chemicals Corporation Information on a collaborative investigative study on the biomonitoring of acrylamide production site workers at the Ciba manufacturing facility in Suffolk, VA.
8EHQ-1207-17009A (PDF)
(6 pp, 218K)
Triisobutyl (methyl) phosphonium toluenesulfonate 344744-05-6 N Confidential Results of a eye irritation/corrosion study in the rabbit and preliminary results of a local lymph node assay in mice.
8EHQ-1207-17010A (PDF)
(2 pp, 117K)
2,3-Dichlorohexafluoro-2-butene 303-04-8 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of 4 toxicity studies: a 1-hour whole-body acute inhalation study in male rats, an acute oral toxicity study in female rats, an acute dermal irritation study in rabbits, and a local lymph node assay in female mice.
8EHQ-1207-17011A (PDF)
(2 pp, 90K)
Pyrethroide, substituted cyclopropanecarboxylate family *2 Confidential   BASF Corporation Results of a 48-hour acute toxicity study in Daphnia magna.
8EHQ-1207-17012A (PDF)
(2 pp, 91K)
Pyrethroide, substituted cyclopropanecarboxylate family *2 Confidential   BASF Corporation Results of a 48-hour acute toxicity study in Daphnia magna.
8EHQ-1207-17013A (PDF)
(3 pp, 104K)
Alkylalkoxysilane and fluoropolymer dispersion in water None   Wacker Chemical Corporation Preliminary results of a nose-only acute aerosol inhalation toxicity study in rats.
8EHQ-1207-17014A (PDF)
(166 pp, 4.3MB)
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo-[d,g][1,2,3]dioxaphosphoci n 6-oxide, lithium salt 85209-93-4 N Japan Technical Information Center, Inc. Reports of four toxicity studies: An acute (nose-only) inhalation study in rats, a 96-hour acute toxicity study in rainbow trout, a 48-hour acute toxicity study in Daphnia magna, and an algal growth inhibition assay.
8EHQ-1207-17015A (PDF)
(2 pp, 102K)
Partially fluorinated condensation polymer mixture *1 Confidential   Confidential Results of an oral gavage 90-day subchronic and one-generation reproductive toxicity study in rats.
Formulation ingredient Confidential
8EHQ-1207-17016A (PDF)
(3 pp, 94K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a 72-hour toxicity study in green algae.
8EHQ-1207-17017A (PDF)
(2 pp, 100K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of contact and oral toxicity tests in honey bees.
Pyrethroide, substituted cyclopropanecarboxylate family *2 Confidential
8EHQ-1207-17018A (PDF)
(2 pp, 63K)
Alkylazine Confidential   Bayer CropScience LP Interim results of a dietary chronic toxicity and carcinogenicity study in rats.
8EHQ-1207-17019A (PDF)
(2 pp, 69K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a single dermal penetration study in rats.
8EHQ-1207-17020A (PDF)
(2 pp, 94K)
Pyrethroide, substituted cyclopropanecarboxylate family *2 Confidential   BASF Corporation Results of a 96-hour acute toxicity study in rainbow trout.
Nitrogen containing heterocycle, substituted *2 Confidential
8EHQ-1207-17021A (PDF)
(1 pg, 47K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results of an acute toxicity study in female rats.
8EHQ-1207-17022A (PDF)
(1 pg, 42K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results of an oral gavage 28-day repeated-dose toxicity study in rats.
8EHQ-1207-17023A (PDF)
(1 pg, 49K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results of an oral gavage 28-day repeated-dose toxicity study in rats.
8EHQ-1207-17024A (PDF)
(1 pg, 47K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results of a dietary 13-week repeated-dose toxicity study in rats.
8EHQ-1207-17025A (PDF)
(1 pg, 50K)
Lauryl lactyl lactate 910661-93-7 N Stepan Company Results of a 96-hour toxicity study in green algae.
8EHQ-1207-17026A (PDF)
(3 pp, 95K)
Confidential Confidential   Confidential Results of a one-generation oral (gavage) reproductive toxicity study in rats.
8EHQ-1207-17027A (PDF)
(7 pp, 249K)
Confidential *2 Confidential   Confidential Results of an oral (gavage) developmental toxicity study in rats.
8EHQ-1207-00373CG (PDF)
(1 pg, 62K)
Fluorochemicals, sulfonate-based and carboxylate-based None   3M Company Supplemental information regarding reports that present laboratory analysis results for off-site water samples collected from water sources in the vicinity of 3M's manufacturing facility in Decatur, AL.
8EHQ-1207-00373CH (PDF)
(3 pp, 151K)
Fluorochemicals, sulfonate-based and carboxylate-based None   3M Company Supplemental information regarding analysis of ground water samples, analysis of public water, wastewater and sludge samples, analysis of groundwater samples, and reanalysis of groundwater, soil, and sediment samples adjacent to 3M's Decatur, AL Manufacturing facility.
8EHQ-1207-16639C (PDF)
(43 pp, 1.5MB)
Chemical None   E.I. du Pont de Nemours and Company Supplemental information regarding confirmed and potential carcinoid tumor cases in the DuPont cancer registry.
8EHQ-1207-16711B (PDF)
(122 pp, 3.2MB)
Fluorinated surfactant salt Confidential   3M Company Final report of an oral gavage developmental toxicity study in rats.
8EHQ-1207-16721I (PDF)
(126 pp, 3MB)
Fluorinated surfactant salt Confidential   3M Company Final report of an oral gavage developmental toxicity study in rats.
8EHQ-1207-16917B (PDF)
(2 pp, 63K)
Confidential Confidential   Confidential Results of a 28-day repeated-inhalation toxicity study in rats.
8EHQ-1207-16932B (PDF)
(153 pp, 2.4MB)
2-Butanone, O,O',O''-(methylsilylidyne) trioxime 22984-54-9 Y Silicones Environmental Health ans Safety Council Final report of a 7-day range finding oral toxicity study in rats.
8EHQ-1207-16971B (PDF)
(1 pg, 54K)
Tetradecyl(tributyl)phosphonium 1,1,2,2-tetrafluoroethanesulfonate None   DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute oral toxicity study in rats.
8EHQ-1207-16986B (PDF)
(1 pg, 54K)
Polyfluorosulfonic acid Confidential   Confidential Results of an oral gavage combined micronucleus and chromosome aberration assay in mice.
FYI-1207-01605A (PDF)
(2 pp, 80K)
Dodecanaminium, N-(carboxymethyl)-N,N-dimethyl-,hydroxide, inner salt 683-10-3 N Rhodia Inc. Results of a range findings oral combined repeated-dose toxicity study with a reproduction/developmental toxicity screen in rats.
Tetradecanaminium, N-(carboxymethyl)-N,N-dimethyl-, hydroxide, inner salt 2601-33-4 N
Potassium chloride *3 7447-40-7 N
FYI-1207-01606A (PDF)
(2 pp, 124K)
Sodium methyl oleoyl taurate *3 137-20-2 Y Exponent, Inc. Results of an oral combined repeated-dose toxicity study with reproduction/ developmental toxicity screen in rats.
FYI-1207-01607A (PDF)
(12 pp, 3.2MB)
Perfluorooctanic acid 335-67-1 N Ciba Specialty Chemicals Corporation Results of a human biomonitoring survey of PFOA and other precursor concentrations in blood sampled from workers at one of Ciba's plants in Germany.
FYI-1207-01608A (PDF)
(2 pp, 129K)
C8-C18 fatty amines and amine acetate salts 61788-46-3 Y Exponent, Inc Results of a range-finding oral gavage repeated-dose toxicity study in rats.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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