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Section 8(e) Substantial Risk Notifications and FYI Submissions Received January 2007

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0107-16709A (PDF)
(3 pp, 1.5MB)
Propanenitrile 185257-15-1 N BASF Corporation Inquiry regarding receipt of section 8(e) submission dated October 6, 2006.
8EHQ-0107-16711A (PDF)
(4 pp, 173K)
Fluorinated surfactant salt None   3M Company Supplemental data from an oral (gavage) developmental toxicity study in rats
8EHQ-0107-16713A (PDF)
(20 pp, 489K)
Oxetane, 3-methyl-3­[(2,2,2-trifluoro­ethoxy)methyl]- *1 156294-54-1 N OMNOVA Solutions, Inc Supplemental information/results from a 28 day repeated-dose oral toxicity study in rats.
8EHQ-0107-16714A (PDF)
(35 pp, 616K)
Cyclopropanecarboxylic acid, 3-hexenyl ester (Z)­*1 188570-78-7 N International Flavors & Fragrances, Inc. Results from a 7-day oral gavage study in rats.
8EHQ-0107-16715A (PDF)
(1 pg, 726K)
1,1,2,2­Tetrafluoroethanesulfonic acid anhydride None   DuPont Haskell Laboratory Results of an acute oral gavage toxicity study (up-and-down method) in rats.
8EHQ-0107-16716A (PDF)
(1 pg, 53K)
1,1,2,2­Tetrafluoroethanesulfonyl chloride 374-42-5 N E.I. du Pont de Nemours and Company Results from an acute oral toxicity study in female rats.
8EHQ-0107-16717A (PDF)
(2 pp, 67K)
Confidential Confidential N Syngenta Crop Protection, Inc. Results from a 90-day oral toxicity study in dogs
8EHQ-0107-16718A (PDF)
(23 pp, 868K)
Confidential Confidential   Schauer Associates Results from an in vitro chromosome aberration test in mammalian cells
8EHQ-0107-16719A (PDF)
(2 pp, 1MB)
Nitrogen containing heterocycles, substituted *2 Confidential   BASF Corporation Results of an acute oral gavage toxicity studies in rats.
8EHQ-0107-16720A (PDF)
(4 pp, 2.2MB)
Nitrogen containing heterocycles, substituted *2 Confidential   BASF Corporation Results of acute toxicity tests in daphnia.
8EHQ-0107-16721A (PDF)
(1 pg, 676K)
Fluorinated surfactant salt Confidential   3M Company Preliminary data for an oral gavage developmental toxicity screening study in rats.
8EHQ-0107-16722A (PDF)
(1 pg, 767K)
2,3,7,8­Tetrachlorodibenzofuran 51207-31-9 N Dow Chemical Company Results of an oral diet reproduction/developmental toxicity study in female minks.
8EHQ-0107-16723A (PDF)
(2 pp, 1.4MB)
Vinylidene fluoride­hexafluoropropene polymer

9011-17-0


N


DuPont Performance Elastomers L.L.C. Results of an acute oral gavage toxicity study in rats.
Benzyltriphenylphosphonium chloride 1100-88-5 N
8EHQ-0107-16724A (PDF)
(2 pp, 959K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of an acute oral gavage toxicity study in rats.
8EHQ-0107-16725A (PDF)
(2 pp, 938K)
Acetic acid, substituted *2 Confidential   BASF Corporation Results of an acute oral gavage toxicity study in rats.
8EHQ-0107-16726A (PDF)
(2 pp, 933K)
Acetic acid, substituted *2 Confidential   BASF Corporation Results of an acute oral gavage toxicity study in rats.
8EHQ-0107-16727A (PDF)
(3 pp, 1.3MB)
Ammonia 7664-41-7 N Texas Commission on Environmental Quality Follow-up on ammonia release reported December 22, 2006.
8EHQ-0107-16731A (PDF)
(18 pp, 12MB)
Confidential Confidential   Johnson Diversey, Inc. Response to allegation of death following exposure to commercial product.
8EHQ-0107-00373BZ (PDF)
(2 pp, 810K)
Fluorochemicals, sulfonate-based None   3M Company Final report on effects of perfluorooctanesulfonate (PFOS) and perfluorohexanesulfonate (PFHS) on body weight, food consumption, and serum cholesterol in 15% dietary fat fed transgenic mice in vivo.
8EHQ-0107-00374J (PDF)
(1 pg, 30K)
Perfluorohexanesulfonate

None

  3M Company Results from an in-vivo toxicity study (diet) in mice.
Perfluorooctanesulfonate 45298-90-6
8EHQ-0107-00394O (PDF)
(2 pp, 813K)
Perfluorooctanesulfonate (PFOS)

45298-90-6


  3M Company Final report on effects of perfluorooctanesulfonate (PFOS) and perfluorohexanesulfonate (PFHS) on body weight, food consumption, and serum cholesterol in 15% dietary fat fed transgenic mice in vivo.
Perfluorohexanesulfonate (PFHS) None
8EHQ-0107-14447C (PDF) Chemicals None   International Institute of Synthetic Rubber Producers, Inc. Report of a follow up epidemiological study of women in the synthetic rubber industry.
8EHQ-0107-15856 Perfluorooctanoic acid (PFOA) (PDF)
(32 pp, 2.27MB)

335-67-1

  DuPont Legal E.I. du Pont de Nemours and Company Supplemental information regarding obtaining a study submitted on January 3, 2007. Copy of published manuscript for estimating human exposure to PFOA
Perfluorooctanoic acid (PDF)
(3 pp, 1.65MB)
335-67-1
8EHQ-0107-15945J (PDF)
(1 pg, 970K)
Anthranilamide, substituted Confidential   Confidential Results of a 90-day oral diet toxicity study in mice.
8EHQ-0107-15945K (PDF)
(2 pp, 78K)
Anthranilamide, substituted Confidential   Confidential Results of a dermal sensitization study in mice
8EHQ-0107-16526C (PDF)
(3 pp, 1.68MB)
Fluorinated alkyloxy acid salt in water Confidential   3M Company Supplemental information regarding dose levels.
8EHQ-0107-16569C (PDF)
(1 pg, 672K)
Q-18, commercial and purified Confidential   Lubrizol Corporation Corrected substantiation of CBI Claims for 8EHQ-06-16569 regarding the sensitization potential of test chemical in the Local Lymph Node Assay.
8EHQ-0107-16571B (PDF)
(315 pp, 7.47MB)
Confidential Confidential   Confidential Final report of a 28-day oral toxicity study in rats
8EHQ-0107-16571C (PDF)
(1 pg, 505K)
None None   PPG Industries, Inc. Correction to 8EHQ document labelled 8EHQ-06-1657.
8EHQ-0107-16628B (PDF)
(1 pg, 52K)
Fluorotelomer alcohol, unsaturated Confidential   Confidential Supplemental information from a 28­day repeated-dose oral toxicity study in rats
8EHQ-0107-16638B (PDF)
(2 pp, 127K)
Ammonium perfluorobutanoate 10495-86-0 N 3M Company Supplemental data from a 28-day repeated-dose oral toxicity study in rats
8EHQ-0107-16647B (PDF)
(283 pp, 5.73MB)
OS213059 None   Lubrizol Corporation Supplemental draft report from a 28­day oral gavage study in rats

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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