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Section 8(e) Substantial Risk Notifications and FYI Submissions Received July 2007

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0707-16886A (PDF)
(2 pp, 58K)
Confidential Confidential   Bayer CropScience LP Results from a 90-day dietary repeated-dose toxicity study in male and female rat.
8EHQ-0707-16887A (PDF)
(2 pp, 81K)
Children's jewelry None   Arent Fox LLP Report of recall of children's jewelry imported from China with possible lead contamination.
8EHQ-0707-16894A (PDF)
(25 pp, 762K)
TPK 50102 (Solvent Yellow 41A ZP crude moist) Confidential   Ciba Specialty Chemicals Inc. Results of a primary eye irritation study in rabbits.
8EHQ-0707-16895A (PDF)
(2 pp, 79K)
Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl) ethylidene]bis- 1478-61-1 N DuPont Haskell Laboratory Results of an algal toxicity study in green algae, acute toxicity study in Daphnia magna and an acute toxicity study in rainbow trout
8EHQ-0707-16896A (PDF)
(14 pp, 366K)
Tetrabutylhexamethylenedi amine (TBHMD) 27090-63-7 Y Solutia, Inc. Preliminary data from an oral reproductive and developmental screening study in male and female rats.
8EHQ-0707-16897A (PDF)
(1 pg, 51K)
Fluorochemical intermediate Confidential   3M Company Preliminary data from a 28-day oral repeated-dose toxicity study in male and female rats.
8EHQ-0707-16898A (PDF)
(1 pg, 49K)
Acrylamide 79-06-1 Y DuPont Haskell Laboratory Results of a 28-day repeated-dose dietary toxicity study in male and female rats.
8EHQ-0707-16899A (PDF)
(2 pp, 74K)
Halogenated pyridine derivative Confidential   Dow Chemical Company Results from an oral gavage mouse micronucleus study.
8EHQ-0707-16906A (PDF)
(2 pp, 113K)
p-Toluenesulfonamide 70-55-3 Y Akzo Nobel Inc. Interim results from a dietrary developmental toxicity study in rabbits.
8EHQ-0707-16907A (PDF)
(2 pp, 111K)
Ethaneperoxoic acid, 1,1-dimethylethyl ester 107-71-1 Y Akzo Nobel Inc. Results of an oral gavage range-finding study in rats for a combined repeated-dose/ reproductive/developmental toxicity study.
8EHQ-0707-16908A (PDF)
(2 pp, 112K)
Hexaneperoxoic acid, 2-ethyl-, 1,1-dimethylethyl ester 3006-82-4 Y Akzo Nobel Inc. Results of an oral gavage range-finding study inrats for a combined reproductive/developmental toxicity study.
8EHQ-0707-16909A (PDF)
(3 pp, 127K)
Zirconium hexanoate *3 22464-99-9 Y Synthetic Organic Chemical Manufacturers Association (SOCMA) Preliminary results of an oral combined repeated-dose toxicity study with reproductive/developmental toxicity screening in rats.
8EHQ-0707-16910A (PDF)
(3 pp, 149K)
Cobalt stearate 13586-84-0 Y Synthetic Organic Chemical Manufacturers Association (SOCMA) Results of an in vitro chromosomal aberrations test and of an oral combined repeated-dose toxicity study with reproductive/developmental toxicity screen in rats.
8EHQ-0707-16911A (PDF)
(3 pp, 144K)
Surface-modified nanoparticle Confidential   3M Company Preliminary data from a 2-week repeated-inhalation toxicity study in rats.
8EHQ-0707-16912A (PDF)
(2 pp, 63K)
Piperidin-derivative Confidential   BASF Corporation Results of an acute eye irritation test in rabbits.
8EHQ-0707-16913A (PDF)
(1 pg, 56K)
Fluorinated aliphatic alcohol Confidential   Confidential Results of an acute oral gavage toxicity study in female rats.
8EHQ-0707-16914A (PDF)
(2 pp, 60K)
Carboxamide Confidential   Bayer CropScience LP Results of a teratology study in rats.
8EHQ-0707-00394S (PDF)
(78 pp, 5.13MB)
Ammonium perfluorooctanoate (APFO) None   DuPont Haskell Laboratory Supplemental report entitled "Ammonium Perfluorooctanoate: Phase II. Retrospective Cohort Mortality Analyses Related to a Serum Biomarker of Exposure in a Polymer Production Plant."
8EHQ-0707-11180B (PDF)
(1 pg, 43K)
Methanesulfonyl chloride 124-63-0 Y Eastman Kodak Company Response to EPA request for copies of study reports.
8EHQ-0707-14151D (PDF)
(3 pp, 134K)
Dioxins Multiple   Dow Chemical Company Supplemental results of a blood monitoring study of Dow's Michigan Operations employees who were potentially exposed to dioxins at a manufacturing facility.
8EHQ-0707-14447D (PDF)
(141 pp, 4.90MB)
Chemicals Multiple   International Institute of Synthetic Rubber Products, Inc. Supplemental information regarding a cohort study of women in the synthetic rubber industry.
8EHQ-0707-15945L (PDF)
(2 pp, 54K)
Anthranilamide, substituted Confidential   Confidential Results of a dermal sensitization study in guinea pigs.
8EHQ-0707-16626B (PDF)
(40 pp, 1.30MB)
Confidential Confidential   Lubrizol Corporation Final report of an acute toxicity study in Daphnia magna.
8EHQ-0707-16638C (PDF)
(1 pg, 33K)
Ammonium perfluoroburanoate (PFBA) 10495-86-0 N 3M Company Final report of a 28-day repeated-dose oral (gastric lavage) toxicity study in rats.
8EHQ-0707-16679C (PDF)
(52 pp, 1.69MB)
Confidential Confidential   Librizol Corporation Final report of acute aquatic toxicity studies in rainbow trout, Daphnia magna, and algae.
8EHQ-0707-16734B (PDF)
(193 pp, 5.89MB)
Creosote 8001-58-9 Y Toxicology Consultants, Inc. Supplemental results from an in vivo dermal absorption study in rats.
8EHQ-0707-16748B (PDF)
(8 pp, 297K)
1,5-Cyclooctadiene 111-78-4 Y Invista Final study report of a 48 hour acute toxicity study in Daphnia magna.
8EHQ-0707-16834B (PDF)
(2 pp, 150K)
1,3-Cyclobutanediol, 2,2,4,4-tetramethyl- 3010-96-6 N Eastman Chemical Company Results from a 90-day repeated-dose oral toxicity study in rats.
8EHQ-0707-16854B (PDF)
(44 pp, 1.57MB)
FC-203CF Light Water Aqueous Film Forming Foam (AFFF) (3%) None   3M Company Supplemental interim analytical report on the analysis of PFOS in aqueous samples from Guin, AL following the release of the commerical product.
FYI-0707-01594A (PDF)
(84 pp, 3.94MB)
Decamethylcyclopentasiloxane *3 541-02-6 Y Dow Corning Company Final report of an in vivo percutaneous absorption study in rats.
FYI-0707-01595A (PDF)
(40 pp, 1.30MB)
Octamethylcyclotetrasiloxane *3 556-67-2 Y Dow Corning Corporation Final report of an in vitro assay to measure binding of D4 to the estrogen receptor.
FYI-0707-01596A (PDF)
(269 pp, 17.09MB)
Decamethylcyclopentasiloxane *3 541-02-6 Y Dow Corning Corporation Final report of a disposition study in rats following a single oral dose in various carriers.
FYI-0707-01597A (PDF)
(3 pp, 92K)
Hexamethyldisiloxane 107-46-0 Y Dow Corning Company Final report of a immunotoxicity assessment in rats following a 28-day, continuous, whole body inhalation exposure.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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