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Section 8(e) Substantial Risk Notifications and FYI Submissions Received November 2007

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1107-16986A (PDF)
(2 pp, 120K)
Polyfluorosulfonic acid Confidential   Confidential Results of an in vitro chromosomal aberration test in Chinese hamster ovary cells and in vivo unscheduled DNA synthesis assay in rat hepatocytes.
8EHQ-1107-16987A (PDF)
(1 pg, 62K)
1,2-Benzenedicarboxylic 85-68-7 Y Ferro Corporation Information on qualitative observations from a biomonitoring study of workers in several industry sectors which utilize the test substance in their operation or products.
8EHQ-1107-16988A (PDF)
(3 pp, 132K)
Cobalt oxide 1307-96-6 N BASF Corporation Results of an acute (4-hour, head-nose exposure) inhalation study in rats.
8EHQ-1107-16989A (PDF)
(2 pp, 101K)
Benzenesulfonamide, substituted *2 Confidential   BASF Corporation Interim results of an extended generation dietary reproduction toxicity range-finding study and 4-week dose range-finding study in rats.
8EHQ-1107-16990A (PDF)
(3 pp, 168K)
Benzenesulfonamide, substituted *2 Confidential   BASF Corporation Interim results of an extended generation dietary reproduction toxicity range-finding study and 4-week dose range-finding study in rats.
8EHQ-1107-16991A (PDF)
(2 pp, 100K)
Nitrogen containing heterocycle, substituted Confidential   BASF Corporation Results of a skin sensitization study (Modified Buehler Test) in guinea pigs.
8EHQ-1107-16992A (PDF)
(2 pp, 82K)
Triazolopyrimidine, substituted *2 Confidential   BASF Corporation Results of a 72-hour toxicity test in green algae.
Epoxide, substituted *2 Confidential
Benzylether *2 Confidential
8EHQ-1107-16993A (PDF)
(2 pp, 103K)
Diethyl phthalate *3 84-66-2 Y Eastman Chemical Company Results of a preliminary screening study on occupational exposure to a panel of phthalates across a range of occupational settings entitled "Urinary Phthalate Metabolite Concentrations Among Workers in Selected Industries".
Dibutyl phthalate *3 84-74-2 Y
Diethylhexyl phthalate 117-81-7 Y
Dimethyl phthalate *3 131-11-3 Y
8EHQ-1107-16994A (PDF)
(2 pp, 81K)
Phosphorodithioic acid, mixed o,o-bis (dialkyl ester), zinc salts, reaction products with iron fluoride [FeF3] *1 None   Platinum Research Organization, Inc. Results of a 5-day oral gavage range-finding study in rats.
8EHQ-1107-16995A (PDF)
(7 pp, 232K)
Confidential *2 Confidential   Confidential Results of an acute oral toxicity study in rats.
8EHQ-1107-16996A (PDF)
(7 pp, 232K)
Confidential *2 Confidential   Confidential Results of an acute oral toxicity study in rats.
8EHQ-1107-16997A (PDF)
(2 pp, 89K)
Aminoethylethanolamine None   EPSDG AEEA Testing Consortium Information regarding the detection of AEEA in groundwater on a site owned by Omya, Inc. in Proctor, Vermont.
8EHQ-1107-16998A (PDF)
(2 pp, 77K)
2-Chloromethyl-1,3-dioxolane 2568-30-1 N Shell Chemical LP Results of 48-hour and 21-day aquatic toxicity studies in Daphnia magna, a 96-hour acute toxicity study in rainbow trout, and a 72-hour toxicity study in green algae.
8EHQ-1107-16999A (PDF)
(2 pp, 72K)
Amorphous silica *3 7631-86-9   DuPont AirProducts NanoMaterials LLC Results of an acute dermal toxicity study in rats.
Tetramethylammonium hydroxide 75-59-2
8EHQ-1107-17000A (PDF)
(2 pp, 71K)
Amorphous silica *3 7631-86-9   DuPont AirProducts NanoMaterials LLC Results of an acute dermal toxicity study in rats.
Tetramethylammonium hydroxide 75-59-2
8EHQ-1107-17001A (PDF)
(2 pp, 84K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of an acute toxicity study in rats.
8EHQ-1107-17002A (PDF)
(2 pp, 76K)
Pyrethroide, substituted cyclopropanecarboxylate family *2 Confidential   BASF Corporation Results of a 72-hour acute oral and contact indicator study in honeybees.
8EHQ-1107-17003A (PDF)
(3 pp, 90K)
Pyrethroide, substituted cyclopropanecarboxylate family *2 Confidential   BASF Corporation Results of a 72-hour acute oral and contact indicator study in honeybees.
8EHQ-1107-17004A (PDF)
(2 pp, 71K)
R&D-227-07 Confidential   BASF Corporation Results of a modified oral gavage reproductive/developmental toxicity screening study in rats.
8EHQ-1107-17005A (PDF)
(2 pp, 128K)
Hexafluoropropylene oxide 428-59-1 Y DuPont Haskell Global Centers for Health and Environmental Sciences Results of an inhalation (whole-body) combined repeated-exposure toxicity study with a reproduction/ developmental toxicity screening test in rats.
8EHQ-1107-00373CF (PDF)
(25 pp, 1MB)
Fluorochemicals, sulfonate-based and carboxylate-based None   3M Company Supplemental information regarding data from the MN Pollution Control based Agency showing detectable levels of perfluorooctanoate in a small sampling of residential wells located new the 3M Cottage Grove production facility.
8EHQ-1107-00394T (PDF)
(1 pg, 44K)
Perfluorooctanoate 335-67-1 N DuPont Haskell Global Centers for Health and Environmental Sciences Supplemental information regarding three publications with copyright restrictions: (1) Cross-sectional study of lipids and liver enzymes related to a serum biomarker of exposure in exposed workers; (2) Llongitudinal study of serum lipids and liver enzymes in workers; (3) Retrospective cohort mortality study of workers in a polymer production plant including a reference population of regional workers.
8EHQ-1107-14708B (PDF)
(2 pp, 86K)
Confidential Confidential   Confidential Results of a combined repeated-inhalation/reproductive/developmental toxicity study in rats.
8EHQ-1107-16360B (PDF)
(2 pp, 98K)
3,3,3-Trifluoromethyl-1,2,2-trifluorovinyl ether 1187-93-5 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a combined repeated-inhalation/reproductive/developmental toxicity screening test in rats.
8EHQ-1107-16436B (PDF)
(2 pp, 138K)
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt Confidential   Confidential Results of an acute eye irritation test in rabbits, acute dermal toxicity study in rats, and an oral gavage combined micronucleus and chromosome aberration assay in bone marrow cells in mice.
8EHQ-1107-16436C (PDF)
(2 pp, 105K)
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt Confidential   Confidential Results of an in vitro mammalian chromosome aberration test using Chinese hamster ovary (CHO) cells.
8EHQ-1107-16478B (PDF)
(2 pp, 110K)
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt Confidential   Confidential Results of an in vitro mammalian chromosome aberration test using Chinese hamster ovary (CHO) cells.
8EHQ-1107-16478C (PDF)
(2 pp, 141K)
Perfluoronated Aliphatic Carboxylic Acid, Ammonium Salt Confidential   Confidential Results of an acute eye irritation test in rabbits, acute dermal toxicity study in rats, and an oral gavage combined micronucleus and chromosome aberration assay in bone marrow cells in mice.
8EHQ-1107-16721H (PDF)
(53 pp, 3.3MB)
Fluorinated surfactant salt Confidential   3M Company Final report of a mouse local lymph node assay.
FYI-1107-01603A (PDF)
(2 pp, 78K)
Diamylamine 2050-92-2 Y American Chemistry Council's Amines Panel Results from a 14-day oral gavage range-finding study in male and female rats.
FYI-1107-01604A (PDF)
(2 pp, 65K)
MAAH Confidential   Evonik Degussa Corporation Reports of a local lymph node assay.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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