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Section 8(e) Substantial Risk Notifications and FYI Submissions Received October 2007

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1007-16958A (PDF)
(1 pg, 45K)
Benzamide Confidential   Bayer CropScience LP Cover letter of a dietary chronic toxicity and carcinogenicity study in the rat.
8EHQ-1007-16959A (PDF)
(2 pp, 61K)
Benzamide Confidential   Bayer CropScience LP Results of a dietary carcinogenicity study in mice.
8EHQ-1007-16960A (PDF)
(73 pp, 2.45MB)
N-[2-(2-oxo-1-imidazolidinyl) ethyl]methacrylamide *1 3089-19-8 N Rhodia Inc. Report from a 28-day oral gavage repeated-dose toxicity study in rats.
Methacrylic acid *3 79-41-4 Y
8EHQ-1007-16961A (PDF)
(8 pp, 221K)
Lead 7439-92-1 N Icemiller LLP Information regarding excess levels of lead and chromium in paint on various manufactured products.
Chromium 7440-47-3 N
8EHQ-1007-16962A (PDF)
(44 pp, 2.86MB)
Lead 7439-92-1 N Dollar General Corporation Notification of test results indicating excess levels of lead found in children's metal jewelry.
8EHQ-1007-16963A (PDF)
(96 pp, 2.62MB)
Tetrapropenylphenol 74499-35-7 Y Lubrizol Corporation Preliminary report of a 90-day dietary repeated-dose toxicity study in rats.
8EHQ-1007-16964A (PDF)
(3 pp, 125K)
Nitrogen containing heterocycles, substituted *2 Confidential   BASF Corporation Results of 96-hour acute toxicity screening tests in fathead minnows (Pimephales promelas).
8EHQ-1007-16965A (PDF)
(2 pp, 75K)
Benzamine, substituted *2 Confidential   BASF Corporation Results of a 48-hour acute aquatic toxicity test in Daphnia magna.
8EHQ-1007-16966A (PDF)
(4 pp, 147K)
Nitrogen containing heterocycles, substituted *2 Confidential   BASF Corporation Results of 48-hour acute toxicity screening tests in Daphnia magna.
8EHQ-1007-16967A (PDF)
(1 pg, 51K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results from a 14-day preliminary oral (dietary) toxicity study in rats.
8EHQ-1007-16968A (PDF)
(10 pp, 1.22MB)
Lead 7439-92-1 N Icemiller LLP Results from additional testing on recalled lead-containing products and the corresponding press releases.
8EHQ-1007-16969A (PDF)
(3 pp, 102K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a 90-day repeated-dose dietary toxicity study in rats.
8EHQ-1007-16970A (PDF)
(2 pp, 81K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a range-finding, prenatal oral (gavage) toxicity study in rats
8EHQ-1007-16971A (PDF)
(1 pg, 48K)
Tetradecyl(tributyl) phosphonium 1,1,2,2- tetrafluoroethanesulfonate None   DuPont Haskell Laboratory Results of an acute dermal toxicity study in rats.
8EHQ-1007-16972A (PDF)
(20 pp, 1.43MB)
Lead 7439-92-1 N Target Corporation Notice information on recalled lead-containing products and the corresponding press releases.
8EHQ-1007-16973A (PDF)
(2 pp, 116K)
di-tert-Butyl peroxide *3 110-05-4 Y Azko Nobel Results from a combined oral (gavage) repeated-dose/ reproductive/ developmental toxicity screen in rats.
8EHQ-1007-16974A (PDF)
(188 pp, 6.27MB)
Lead 7439-92-1 N Kids II, Inc. Information on the testing of lead-containing products, a voluntary recall of such products, and the corresponding press release.
8EHQ-1007-16975A (PDF)
(3 pp, 188K)
Acrylonitrile 107-13-1 Y Acrylonitrile Group Information from sevearl genetic toxicity studies including: a 4-week oral HGPRT genetic toxicity study in female rats and mice; an in-vitro DNA adduct study; an in-vivo DNA adduct study in rats; and a DNA damage (comet) assay in the forestomach and liver cells of mice.
8EHQ-1007-16976A (PDF)
(7 pp, 235K)
Confidential *2 Confidential   Confidential Results of an acute oral toxicity study in female rats.
8EHQ-1007-16977A (PDF)
(3 pp, 179K)
Poly[oxy[trifluoro(trifluoromethyl)-1,2-ethanediyl]], alpha-(1-carboxy-1,2,2,2-tetrafluoroethyl)-omega-[tetrafluoro (trifluoromethyl)ethoxy]- 51798-33-5 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a dermal sensitization study (Murine Local Lymph Node Assay) in female mice.
8EHQ-1007-16978A (PDF)
(51 pp, 1.64MB)
Confidential Confidential   Confidential Final report of a gene mutation test in Salmonella typhimurium and Escherichia coli.
8EHQ-1007-16979A (PDF)
(51 pp, 1.71MB)
Confidential Confidential   Confidential Final report of a gene mutation assy in Salmonella typhimurium and Escherichia coli.
8EHQ-1007-16980A (PDF)
(2 pp, 69K)
Pyrimidine derivatives *2 Confidential   BASF Corporation Results of in-vivo oral mouse micronucleus screening tests.
8EHQ-1007-16981A (PDF)
(2 pp, 69K)
Reaction product of sodium silicophosphonate and sodium metasilicate Confidential   BASF Corporation Results of a 90-day oral (gavage) repeated-dose toxicity study in rats.
8EHQ-1007-16982A (PDF)
(1 pg, 46K)
5-Methyl-1-pentylpyrrolidin-2-one 764718-02-7 N Confidential Results of a range-finding oral (gavage) developmental toxicity study in rats.
8EHQ-1007-16983A (PDF)
(1 pg, 60K)
Difluoro (fluorosulfonyl) acetyl fluoride 677-67-8 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an in vitro gene mutation study in Salmonella tyhpimurium and Escherichia coli.
8EHQ-1007-16984A (PDF)
(3 pp, 210K)
Linear alkylbenzene alkylate bottoms Multiple   Council for LAB/LAS Environmental Research (CLER) and the Linear Alkylbenzene Alkylate Bottoms Consortium Preliminary results of a combined oral (gavage) repeated-dose toxicity study with reproductive/ developmental toxicity screen in rats.
8EHQ-1007-16985A (PDF)
(1 pg, 42K)
Pyrimidine, substituted Confidential   Confidential Results of an oral range-finding developmental toxicity study in rabbits.
8EHQ-007-00373CE (PDF)
(52 pp, 2.01MB)
Fluorochemicals, sulfonate-based and carboxyloc-based None   3M Company Final report of a cohort mortality study of workers at the former 3M ammonium perfluorooctanoate production facility in Cottage Grove, MN.
8EHQ-1007-15211G (PDF)
(3827 pp, 105MB)
Confidential Confidential   Confidential Supplemental data regarding an oral female pubertal assay in juvenile female rat and additional supporting studies further examining related endpoints.
8EHQ-1007-16105H (PDF)
(1 pg, 48K)
Thiophene derivative, substituted Confidential   Confidential Preliminary results of a subchronic dietary neurotoxicity study in rats.
8EHQ-1007-16721G (PDF)
(1 pg, 49K)
Fluorinated surfactant salt None   3M Company Supplemental information regarding a local lymph node assay in mice.
8EHQ-1007-16750B (PDF)
(44 pp, 2.87MB)
Polyquaternary amine Confidential   Nalco Company Final report of an acute inhalation study in rats.
8EHQ-1007-16785C (PDF)
(1 pg, 40K)
Anionic aqueous acrylate polymer dispersion Confidential   Confidential Supplemental information regarding an acute inhalation toxicity study in male rats.
8EHQ-1007-16817B (PDF)
(1 pg, 46K)
Sulfoxamine Confidential   Dow Chemical Company Supplemental information regarding a 30-day repeated-dose oral feed toxicity study in mice.
8EHQ-1007-16820B (PDF)
(184 pp, 5.50MB)
Phenol, 4,4'-(1-methylethylidene)bis- 80-05-7 Y American Chemistry Council Polycarbonate/BP A Global Group Final reports of two terrestrial plant toxicity (seedling emergence and seedling growth) studies.
8EHQ-1007-16916B (PDF)
(2 pp, 82K)
Fluoroalkyl carboxylic acid, ammonium salt Confidential   Confidential Results of acute oral toxicity studies in rats and mice.
8EHQ-1007-16916C (PDF)
(1 pg, 73K)
Fluoroalkyl carboxylic acid, ammonium salt Confidential   Confidential Results of an in vitro mammalian chromosomal aberration test in Chinese Hamster Ovary (CHO) cells.
8EHQ-1007-16947B (PDF)
(3 pp, 114K)
CN-2065 *1 Confidential   Chemtura Supplemental information regarding substantiation of Confidential Business Information claim.
8EHQ-1007-16957B (PDF)
(7 pp, 599K)
Lead 7439-92-1 N Target Corporation Supplemental information regarding certain recalled products containing lead.
FYI-1007-01601A (PDF)
(147 pp, 4.32MB)
Hexamethyldisiloxane 107-46-0 Y Dow Corning Corporation Final report on the determination of the reverse binding of HMDS/ metabolites to alpha 2u-globulin in male rats following oral gavage administration.
FYI-1007-01602A (PDF)
(367 pp, 13.7MB)
Decamethylcyclopentasiloxane *3 541-02-6 Y Dow Corning Corporation Final report on an absorption, distribution, metabolism and excretion (ADME) study in rats following a 14-day nose-only vapor inhalation expsoure followed by a single nose-only vapor inhalation exposure to radiolabelled test substance on day 15.

*1 = PMN; *2 = Pesticide; * 3 = Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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