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Section 8(e) Substantial Risk Notifications and FYI Submissions Received August 2008

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0808-17208A (PDF)
(2 pp, 92K)
Carbon Nano Tube Confidential BASF Chemical Company Results of a subchronic inhalation study in rats.
8EHQ-0808-17229A (PDF)
(4 pp, 162K)
Perfluorooctanoate (PFOA) 3825-26-1 DuPont Haskell Laboratory Summary of occupational PFOA serum results for workers at the DuPont Changshu Facility in China for samples collected in 2007 (baseline year) and 2008.
8EHQ-0808-17230A (PDF)
(4 pp, 162K)
Trimethoxyphenylsilane 2996-92-1 N Silicones Environmental, Health and Safety Council (SEHSC) Summary information concerning an ongoing in vitro chromosome aberration test in Chinese hamster V79 cells in the presence and absence of metabolic activation (RCC-CCR study number: 1175600).
8EHQ-0808-17231A (PDF)
(2 pp, 76K)
2,4,4-trimethyl pentene 25167-70-8 Y Lyondell Chemical Company Test summaries from the following studies: Delayed contact hypersensitivity study in the guinea pig (final report by Huntingdon Life Science, UK; Report No. 96/SOC005/0902) and acute toxicity to rainbow trout (Oncorhynchus mykiss), daphnia (Daphnia magna) and green algae (Raphidocelis subcapitata) (final report by Shell Research and Technology Centre, Thornton, Chester, UK; Study No. 6405).
8EHQ-0808-17232A (PDF)
(9 pp, 997K)
Ethyl tertiary butyl ether (ETBE) 637-92-3 Y Lyondell Chemical Company Results from a single generation oral (gavage) reproduction study in rats and a soil biodegradation study as part of the ETBE Utilization Study Working Group Testing Program and Risk Assessment.
8EHQ-0808-17233A (PDF)
(2 pp, 87K)
Alkylazine Confidential Bayer CropScience LP Summary of a dietary developmental neurotoxicity study with technical grade BCS in Wistar rats (study No. 201877).
8EHQ-0808-17234A (PDF)
(9 pp, 355K)
2-amino-4-dimethylamino6-(2,2,2-trifluoroethoxy) 1,3,5-triazin- *1

T3009

145963-84-4



32998-04-2
N



N
DuPont Haskell Laboratories


DuPont Haskell Laboratories
Information from a call report and/or telephone calls from/with the Rocky Mountain Poison and Drug Center and/or Chemtrec regarding exposure of 2 adult males via inhalation of chemical from a dumpster at a shipping site.
8EHQ-0808-17235A (PDF)
(32 pp, 1.24MB)
9,10-anthraquinone 84-65-1 Y American Forest & Paper Association, Inc. Results from 2 tests relevant to the potential for human exposure to the test substance that may be contained in paper or paperboard: (1) the potential for migration of anthraquinone from unbleached linerboard (special report No. 08-02 conducted by the National Council for Air and Stream Improvement (NCASI) West Coast Regional Center, Corvallis, Oregon; July 2008) and (2) determination of the anthraquinone paper/paperboard simulated sweat partition coefficient for the estimation of potential dermal contact exposure (special report No. 08-03 conducted by NCASI West Coast Regional Center, Corvallis, Oregon; July 2008).
8EHQ-0808-17236A (PDF)
(2 pp, 72K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of an acute oral (gavage) toxicity study in Wistar rats.
8EHQ-0808-17237A (PDF)
(2 pp, 68K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of an acute oral (gavage) toxicity study in Wistar rats.
8EHQ-0808-17238A (PDF)
(3 pp, 122K)
Quinone Confidential   BASF Corporation Results of a 72-hour aquatic toxicity study on green algae (Pseudokirchneriella subcapitata) growth.
8EHQ-0808-17239A (PDF)
(2 pp, 109K)
Quinone Confidential   BASF Corporation Results of a 48h acute toxicity study in daphnia (Daphnia magna).
8EHQ-0808-17240A (PDF)
(2 pp, 128K)
Nitrogen containing heterocycle, substituted Confidential   BASF Corporation Results of a 96h aquatic toxicity study on green algae (Pseudokirchneriella subcapitata) growth.
8EHQ-0808-17241A (PDF)
(6 pp, 230K)
Alkylated urea resin (>65%)

Proprietary solvent (<15%)

Water (<10%)

Ethanol (<10%)
None

None

773-18-5

64-17-5
  Confidential Preliminary results of an Ames screening assay.Results of an acute inhalation study in rats.
8EHQ-0808-17242A (PDF)
(2 pp, 134K)
Potassium chloride *3




Tetradecanaminium, N(carboxymethyl)-N,Ndimethyl-, hydroxide, inner salt

Dodecanaminium, N(carboxymethyl)-N,Ndimethyl-,hydroxide, inner salt

water *3
7447-40-7




2601-33-4



683-10-3



7732-18-5
Y




N



N



Y
UBMITTER Rhodia Inc. Results of an oral (gavage) range-finding study for a combined repeated-dose toxicity study with a reproduction/developmental toxicity screening test.
8EHQ-0808-17243A (PDF)
(2 pp, 65K)
Dinitrile Confidential BASF Corporation Results of an acute toxicity study in the water flea (Daphnia magna).
8EHQ-0808-17244A (PDF)
(2 pp, 86K)
Nitrogen containing heterocycle, substituted *2 Confidential BASF Corporation Results of an oral (dietary) two-generation reproduction toxicity study in rats.
8EHQ-0808-17245A (PDF)
(2 pp, 66K)
Dinitrile Confidential BASF Corporation Results of a 48h acute toxicity study in water fleas (Daphnia magna).
8EHQ-0808-17246A (PDF)
(2 pp, 86K)
Nitrogen containing heterocycle B, substituted

Nitrogen containing heterocycle A, substituted
Confidential


Confidential
BASF Corporation Results of a 96h acute toxicity study in freshwater fish (Oncorhynchus mykiss).
8EHQ-0808-00373CP (PDF)
(2 pp, 76K)
Fluorochemicals, sulfonate-based and carboxylate-based Multiple 3M Company Final analytical reports for sampling activities conducted in the vicinity of the 3M Decatur, Alabama manufacturing facililty: (1) MPI Research Stuyd No. 0137.0219; Project No. P0003267: Interim Report 3- Analysis of Fish and Clam Samples; Study title: Analysis of perfluorooctanoic acid (PFOA) in water, soil, sediment, fish, and clams using LC/MS/MS for the 3M Decatur monitoring program); (2) MPI Research Study No. 0137.0219; Project No. P0003268: Interim Report 3- Analysis of Fish and Clam samples; Study title: Analysis of perfluorobutanesulfonate (PFBS), perfluorohexanesulfonate (PFHS), and perfluorooctanesulfonate (PFOS) in water, soil, sediment, fish, and clams using LC/MS/MS for the 3M Decatur monitoring program.
8EHQ-0808-00373CQ (PDF)
(139 pp, 4.79MB)
Perfluorooctanesulfonate (PFOS) 2795-39-3 3M Company Supplemental information from a 13 week dietary study in male Sprague-Dawley rats designed to investigate the reversibility of hepatomegally and thyroid effects previously demonstrated in rats exposed to the test substance.
8EHQ-0808-16561B (PDF)
(6 pp, 276K)
Hydrofluoroether (77.9%)

Fluoroolefins (21.3%)
870778-34-0

None
3M Company Final report of an acute inhalation toxicity study on a fluorochemical manufacturing process stream in rats.
8EHQ-0808-17241B (PDF)
(4 pp, 107K)
Confidential Confidential Confidential Final report of a Salmonella/ Mammalian-Microsome reverse mutation screening study.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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