Jump to main content.


Section 8(e) Substantial Risk Notifications and FYI Submissions Received December 2008

You will need Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.


8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1208-17327A (PDF)
(3 pp, 146K)
2-ethylhexyl4-aminobenzoate 26218-04-2   BASF Corporation Results of a 72 hour growth inhibition toxicity test in green algae (Scendesmus subspicatus)
8EHQ-1208-17328A (PDF)
(2 pp, 81K)
2-ethylhexyl4-aminobenzoate 26218-04-2   BASF Corporation Results of a 48-hour acute toxicity study in water fleas (Daphnia magna)
8EHQ-1208-17329A (PDF)
(2 pp, 89K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a 7-day acute toxicity test on aquatic water plants (Lemna gibba)
8EHQ-1208-17330A (PDF)
(2 pp, 75K)
Nitrogen containing heterocycle, substituted (Substance A) *2 Confidential   BASF Corporation Results of an acute oral (dietary) toxicity study in Wistar rats
Nitrogen containing heterocycle, substituted (Substance B) *2 Confidential   BASF Corporation Results of an acute oral (dietary) toxicity study in Wistar rats
Nitrogen containing heterocycle, substituted (Substance C) *2 Confidential   BASF Corporation Results of an acute oral (dietary) toxicity study in Wistar rats
Nitrogen containing heterocycle, substituted (Substance D) *2 Confidential   BASF Corporation Results of an acute oral (dietary) toxicity study in Wistar rats
8EHQ-1208-17331A (PDF)
(2 pp, 88K)
Dinitrile Confidential   BASF Corporation Results of a 96-hour acute toxicity study in freshwater fish (Oncorhynchus mykiss)
8EHQ-1208-17332A (PDF)
(2 pp, 84K)
Nitrogen containing heterocycle, substituted *2 Confidential   BASF Corporation Results of a repeated dose 28-day oral (dietary) toxicity study in Wistar rats
8EHQ-1208-17333A (PDF)
(5 pp, 133K)
Formaldehyde, reaction products with N1-phenyl-1,4-benzenediamine Confidential   Lubrizol Corporation Preliminary results of an acute oral toxicity study in rats
8EHQ-1208-17334A (PDF)
(1 pg, 70K)
3-amino-4-octanol 1001354-72-8   The Dow Chemical Company Results of an oral (gavage) reproduction/developmental toxicity study in rats.
8EHQ-1208-17335A (PDF)
(1 pg, 64K)
substituted imidazole Confidential   Syngenta Crop Protection, Inc. Results of an acute toxicity/toxicokinetic sampling study in the rat.
8EHQ-1208-17339A (PDF)
(1 pg, 82K)
Substituted Nitrogen Containing Heterocycles Confidential   Confidential Results of an in vivo micronucleus assay in mice
8EHQ-1208-17340A (PDF)
(2 pp, 115K)
1,1,2,2-Tetrafluoroethane 359-35-3   DuPont Haskell Laboratory Results of an acute inhalation toxicity study in rats
8EHQ-1208-17341A (PDF)
(1 pg, 54K)
carboxylated polymer, sulfonated aromatic condensate and anionic surfactant Confidential   Confidential Results of an eye irritation study in rabbits
8EHQ-1208-17342A (PDF)
(4 pp, 188K)
1,1,1,3,5,5,5-Heptamethyltrisiloxane 1873-88-7 N Dow Corning Results from two studies:
Study 1 - Acute oral toxicity study in the rat (up and down procedure)

Study 2 - A dose range-finding study for a combined repeated dose toxicity study with the reproductive/developmental toxicity screening test
8EHQ-1208-17343A (PDF)
(2 pp, 85K)
Dinitrile Confidential   BASF Corporation Results of an acute immobilization test in water flea
8EHQ-1208-17344A (PDF)
(2 pp, 75K)
substituted nitrogen containing heterocycle *2 Confidential   BASF Corporation Results of an acute toxicity study on honey bee
8EHQ-1208-17345A (PDF)
(2 pp, 73K)
substituted nitrogen containing heterocycle *2 Confidential   BASF Corporation Results of Acute Toxicity Study on Honey Bee
8EHQ-1208-17346A (PDF)
(2 pp, 73K)
substituted nitrogen containing heterocycle *2 Confidential   BASF Corporation Results of acute toxicity study on honey bee
8EHQ-1208-17347A (PDF)
(3 pp, 87K)
Perfluorooctanoic Acid 335-67-1 N DuPont Haskell Laboratory Results of occupational blood sampling for PFOA
8EHQ-1208-17348A (PDF)
(2 pp, 75K)
substituted tetrahydronapthalene Confidential   Syngenta Crop Protection, Inc. Results of a preliminary dietary study in mice
8EHQ-1208-17349A (PDF)
(2 pp, 79K)
substituted tetrahydronapthalene Confidential   Syngenta Crop Protection, Inc. Results of a dietary tolerability study in rabbits
8EHQ-1208-17350A (PDF)
(2 pp, 99K)
Emulsifier Confidential   Confidential Results of an acute oral toxicity study in rats, an in vitro mammalian chromosome aberration test, and an acute eye irritation test in rabbits
8EHQ-1208-17351A (PDF)
(3 pp, 129K)
TDA Vicinal None   BASF Corporation Results of a Repeated Dose Oral (gavage) Toxicity Study in Wistar Rats with TDA Vicinal
8EHQ-1208-17353A (PDF)
(49 pp, 1.54MB)
epoxide substituted bicyclic olefin Confidential   Confidential Results of an in vitro Ames Test using Salmonella typhimurium and Escherichia coli and an in vitro L5178Y +/- Mouse Lymphoma assay.
8EHQ-1208-17354A (PDF)
(7 pp, 309K)
Isohexanes, N-hexane > 5% (68.2%) None   Sigma-Aldrich Corporation Information regarding the death of a 47 year old male laboratory technician employed by Sepracor in Windsor, Nova Scotia as a result of post-exposure pulmonary edema.
(Trimethylsilyl) diazomethane (31.8%) 18107-18-1 N
8EHQ-1208-17355A (PDF)
(3 pp, 144K)
1,1,1,3,5,5,5,-Heptamethyl-3-(propyl(poly(EO))methyl) tisiloxane 27306-78-1 N Dow Corning Corporation Information from a dose range-finding study for a combined repeated dose toxicity study with a reproductive/developmental toxicity screening test in rats.
8EHQ-1208-17356A (PDF)
(3 pp, 170K)
 Dimethylsilanediol 1066-42-8 N Dow Coming Corporation Results of an acute oral gavage toxicity study in mice.
8EHQ-1208-17357A (PDF)
(12 pp, 379K)
Hexamethyldisiloxane 107-46-0 Y Dow Coming Corporation Results of an inhalation two-Generation Reproductive Toxicity Study in Rats, including Developmental Neurotoxicity Assessment of the F2 Generation.
8EHQ-1208-17358A (PDF)
(1 pg, 62.2K)
3-amino-4-octanol 1001354-72-8 N Dow Chemical Company Results of an acute oral gavage toxicity study in Crl:CDl(ICR) mice.
8EHQ-1208-17359A (PDF)
(3 pp, 153K)
Dimethylsilanediol 1066-42-8 N Silicones Environmental, Health and Safety Council (SEHSC) Results of an ongoing combined inhalation repeated dose toxicity study with a reproductive/ developmental toxicity screening test in rats.
8EHQ-1208-17360A (PDF)
(7 pp, 567K)
Acetylsalicylic acid 50-78-2 N DuPont Haskell Global Centers for Health and Environmental Science Results of a pre-1977 (1967) concentration x time acute inhalation toxicity study in guinea pigs.
8EHQ-1208-17362A (PDF)
(4 pp, 129K)
Hydraulic fluid None   MillerCoors LLC Written report for the November 30, 2008 hydraulic fluid spill.
8EHQ-1208-00373CS (PDF)
(34 pp, 849K)
Perfluorocarboxylates (C4-12) Multiple   3M Environmental, Health and Safety Operations A presentation Analysis of the Homologus Series of Perfluorocarboxylates - Perfluorobutanoate (C4) through PerfIuorododecanoate (C12) from American Red Cross Adult Blood Donors, 2006, by Geary Olsen, Mark Ellefson, and William Reagen. This presentation wa.
8EHQ-1208-14235B (PDF)
(3 pp, 210K)
Ethyl, 4-phenoxyphenyl 2-substituted proprionate Confidential   DuPont Haskell Global Centers Results of aquatic, mutagenicity, and mammalian toxicity studies.
8EHQ-1208-14447E (PDF)
(22 pp, 552K)
1,3-Butadiene 106-99-0 Y International Institute of Synthetic Rubber Producers, Inc. Summary of analysis of lung cancer among women and men in the North American synthetic rubber industry.  Attachment includes summary of analyses in the form of a presentation to the sponsors; "Lung Cancer Among Women and Men in the North American Synthet
8EHQ-1208-15945Q (PDF)
(1 pg, 61K)
Substituted Anthranilamide Confidential   Confidential Results of a dermal sensitization study (Buehler method) in guinea pigs.
8EHQ-1208-16105N (PDF)
(1 pg, 79K)
Confidential Confidential   DuPont Haskell Laboratory Results of an acute toxicity study in Daphnia magna
8EHQ-1208-16436G (PDF)
(1 pg, 78K)
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt Confidential   Confidential Results of a 21-day static renewal chronic Daphnia magna study
8EHQ-1208-16478G (PDF)
(1 pg, 90K)
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt Confidential   Confidential Results of a chronic Daphnia magna study
8EHQ-1208-16778B (PDF)
(142 pp, 9.13MB)
Trimethylsilanol 1066-40-6 N Silicones Environmental Health and Safety Council Results of a 2-week whole-body inhalation toxicity range-finder study in albino rats and 28-day whole-body repeated dose inhalation toxicity study with reproductive/ developmental screening in albino rats
8EHQ-1208-17079D (PDF)
(2 pp, 548K)
Sepiolite Nanoclay - Organically Modified Hydrated Magnesium Silicate None   DuPont Haskell Laboratory Response to the Agency's request for a complete report of pulmonary bioassay screening study
Sepiolite - Hydrated Magnesium Silicate 63800-37-3 N
8EHQ-1208-17187B (PDF)
(3 pp, 196K)
Triethoxyoctylsilane 2943-75-1 Y Silicones Environmental Health and Safety Council (SEHSC) Information concerning an combined oral (gavage) repeated dose toxicity study with a reproductive -developmental toxicity screening test  in rats.
8EHQ-1208-17277B (PDF)
(1 pg, 44K)
Crude Oil Confidential   Confidential A letter stating the sponsor's relinquishment of the confidentiality claim regarding the chemical substance identity for crude oil (8EHQ-08-17277A).

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


Local Navigation


Jump to main content.