![[logo] US EPA](http://www.epa.gov/epafiles/images/logo_epaseal.gif){kind=logo}
8(e) and FYI Submissions Received December 2008
You will need Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.
8EHQ# |
CHEM NAME(S) |
CAS NO.(S) |
USHV |
SUBMITTER |
DESCRIPTION |
| 8EHQ-1208-17327A (PDF) (3 pp, 146K) |
2-ethylhexyl4-aminobenzoate | 26218-04-2 | BASF Corporation | Results of a 72 hour growth inhibition toxicity test in green algae (Scendesmus subspicatus) | |
| 8EHQ-1208-17328A (PDF) (2 pp, 81K) |
2-ethylhexyl4-aminobenzoate | 26218-04-2 | BASF Corporation | Results of a 48-hour acute toxicity study in water fleas (Daphnia magna) | |
| 8EHQ-1208-17329A (PDF) (2 pp, 89K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Results of a 7-day acute toxicity test on aquatic water plants (Lemna gibba) | |
| 8EHQ-1208-17330A (PDF) (2 pp, 75K) |
Nitrogen containing heterocycle, substituted (Substance A) *2 | Confidential | BASF Corporation | Results of an acute oral (dietary) toxicity study in Wistar rats | |
| Nitrogen containing heterocycle, substituted (Substance B) *2 | Confidential | BASF Corporation | Results of an acute oral (dietary) toxicity study in Wistar rats | ||
| Nitrogen containing heterocycle, substituted (Substance C) *2 | Confidential | BASF Corporation | Results of an acute oral (dietary) toxicity study in Wistar rats | ||
| Nitrogen containing heterocycle, substituted (Substance D) *2 | Confidential | BASF Corporation | Results of an acute oral (dietary) toxicity study in Wistar rats | ||
| 8EHQ-1208-17331A (PDF) (2 pp, 88K) |
Dinitrile | Confidential | BASF Corporation | Results of a 96-hour acute toxicity study in freshwater fish (Oncorhynchus mykiss) | |
| 8EHQ-1208-17332A (PDF) (2 pp, 84K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Results of a repeated dose 28-day oral (dietary) toxicity study in Wistar rats | |
| 8EHQ-1208-17333A (PDF) (5 pp, 133K) |
Formaldehyde, reaction products with N1-phenyl-1,4-benzenediamine | Confidential | Lubrizol Corporation | Preliminary results of an acute oral toxicity study in rats | |
| 8EHQ-1208-17334A (PDF) (1 pg, 70K) |
3-amino-4-octanol | 1001354-72-8 | The Dow Chemical Company | Results of an oral (gavage) reproduction/developmental toxicity study in rats. | |
| 8EHQ-1208-17335A (PDF) (1 pg, 64K) |
substituted imidazole | Confidential | Syngenta Crop Protection, Inc. | Results of an acute toxicity/toxicokinetic sampling study in the rat. | |
| 8EHQ-1208-17339A (PDF) (1 pg, 82K) |
Substituted Nitrogen Containing Heterocycles | Confidential | Confidential | Results of an in vivo micronucleus assay in mice | |
| 8EHQ-1208-17340A (PDF) (2 pp, 115K) |
1,1,2,2-Tetrafluoroethane | 359-35-3 | DuPont Haskell Laboratory | Results of an acute inhalation toxicity study in rats | |
| 8EHQ-1208-17341A (PDF) (1 pg, 54K) |
carboxylated polymer, sulfonated aromatic condensate and anionic surfactant | Confidential | Confidential | Results of an eye irritation study in rabbits | |
| 8EHQ-1208-17342A (PDF) (4 pp, 188K) |
1,1,1,3,5,5,5-Heptamethyltrisiloxane | 1873-88-7 | N | Dow Corning | Results from two studies: Study 1 - Acute oral toxicity study in the rat (up and down procedure) Study 2 - A dose range-finding study for a combined repeated dose toxicity study with the reproductive/developmental toxicity screening test |
| 8EHQ-1208-17343A (PDF) (2 pp, 85K) |
Dinitrile | Confidential | BASF Corporation | Results of an acute immobilization test in water flea | |
| 8EHQ-1208-17344A (PDF) (2 pp, 75K) |
substituted nitrogen containing heterocycle *2 | Confidential | BASF Corporation | Results of an acute toxicity study on honey bee | |
| 8EHQ-1208-17345A (PDF) (2 pp, 73K) |
substituted nitrogen containing heterocycle *2 | Confidential | BASF Corporation | Results of Acute Toxicity Study on Honey Bee | |
| 8EHQ-1208-17346A (PDF) (2 pp, 73K) |
substituted nitrogen containing heterocycle *2 | Confidential | BASF Corporation | Results of acute toxicity study on honey bee | |
| 8EHQ-1208-17347A (PDF) (3 pp, 87K) |
Perfluorooctanoic Acid | 335-67-1 | N | DuPont Haskell Laboratory | Results of occupational blood sampling for PFOA |
| 8EHQ-1208-17348A (PDF) (2 pp, 75K) |
substituted tetrahydronapthalene | Confidential | Syngenta Crop Protection, Inc. | Results of a preliminary dietary study in mice | |
| 8EHQ-1208-17349A (PDF) (2 pp, 79K) |
substituted tetrahydronapthalene | Confidential | Syngenta Crop Protection, Inc. | Results of a dietary tolerability study in rabbits | |
| 8EHQ-1208-17350A (PDF) (2 pp, 99K) |
Emulsifier | Confidential | Confidential | Results of an acute oral toxicity study in rats, an in vitro mammalian chromosome aberration test, and an acute eye irritation test in rabbits | |
| 8EHQ-1208-17351A (PDF) (3 pp, 129K) |
TDA Vicinal | None | BASF Corporation | Results of a Repeated Dose Oral (gavage) Toxicity Study in Wistar Rats with TDA Vicinal | |
| 8EHQ-1208-17353A (PDF) (49 pp, 1.54MB) |
epoxide substituted bicyclic olefin | Confidential | Confidential | Results of an in vitro Ames Test using Salmonella typhimurium and Escherichia coli and an in vitro L5178Y +/- Mouse Lymphoma assay. | |
| 8EHQ-1208-17354A (PDF) (7 pp, 309K) |
Isohexanes, N-hexane > 5% (68.2%) | None | Sigma-Aldrich Corporation | Information regarding the death of a 47 year old male laboratory technician employed by Sepracor in Windsor, Nova Scotia as a result of post-exposure pulmonary edema. | |
| (Trimethylsilyl) diazomethane (31.8%) | 18107-18-1 | N | |||
| 8EHQ-1208-17355A (PDF) (3 pp, 144K) |
1,1,1,3,5,5,5,-Heptamethyl-3-(propyl(poly(EO))methyl) tisiloxane | 27306-78-1 | N | Dow Corning Corporation | Information from a dose range-finding study for a combined repeated dose toxicity study with a reproductive/developmental toxicity screening test in rats. |
| 8EHQ-1208-17356A (PDF) (3 pp, 170K) |
Dimethylsilanediol | 1066-42-8 | N | Dow Coming Corporation | Results of an acute oral gavage toxicity study in mice. |
| 8EHQ-1208-17357A (PDF) (12 pp, 379K) |
Hexamethyldisiloxane | 107-46-0 | Y | Dow Coming Corporation | Results of an inhalation two-Generation Reproductive Toxicity Study in Rats, including Developmental Neurotoxicity Assessment of the F2 Generation. |
| 8EHQ-1208-17358A (PDF) (1 pg, 62.2K) |
3-amino-4-octanol | 1001354-72-8 | N | Dow Chemical Company | Results of an acute oral gavage toxicity study in Crl:CDl(ICR) mice. |
| 8EHQ-1208-17359A (PDF) (3 pp, 153K) |
Dimethylsilanediol | 1066-42-8 | N | Silicones Environmental, Health and Safety Council (SEHSC) | Results of an ongoing combined inhalation repeated dose toxicity study with a reproductive/ developmental toxicity screening test in rats. |
| 8EHQ-1208-17360A (PDF) (7 pp, 567K) |
Acetylsalicylic acid | 50-78-2 | N | DuPont Haskell Global Centers for Health and Environmental Science | Results of a pre-1977 (1967) concentration x time acute inhalation toxicity study in guinea pigs. |
| 8EHQ-1208-17362A (PDF) (4 pp, 129K) |
Hydraulic fluid | None | MillerCoors LLC | Written report for the November 30, 2008 hydraulic fluid spill. | |
| 8EHQ-1208-00373CS (PDF) (34 pp, 849K) |
Perfluorocarboxylates (C4-12) | Multiple | 3M Environmental, Health and Safety Operations | A presentation Analysis of the Homologus Series of Perfluorocarboxylates - Perfluorobutanoate (C4) through PerfIuorododecanoate (C12) from American Red Cross Adult Blood Donors, 2006, by Geary Olsen, Mark Ellefson, and William Reagen. This presentation wa. | |
| 8EHQ-1208-14235B (PDF) (3 pp, 210K) |
Ethyl, 4-phenoxyphenyl 2-substituted proprionate | Confidential | DuPont Haskell Global Centers | Results of aquatic, mutagenicity, and mammalian toxicity studies. | |
| 8EHQ-1208-14447E (PDF) (22 pp, 552K) |
1,3-Butadiene | 106-99-0 | Y | International Institute of Synthetic Rubber Producers, Inc. | Summary of analysis of lung cancer among women and men in the North American synthetic rubber industry. Attachment includes summary of analyses in the form of a presentation to the sponsors; "Lung Cancer Among Women and Men in the North American Synthet |
| 8EHQ-1208-15945Q (PDF) (1 pg, 61K) |
Substituted Anthranilamide | Confidential | Confidential | Results of a dermal sensitization study (Buehler method) in guinea pigs. | |
| 8EHQ-1208-16105N (PDF) (1 pg, 79K) |
Confidential | Confidential | DuPont Haskell Laboratory | Results of an acute toxicity study in Daphnia magna | |
| 8EHQ-1208-16436G (PDF) (1 pg, 78K) |
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt | Confidential | Confidential | Results of a 21-day static renewal chronic Daphnia magna study | |
| 8EHQ-1208-16478G (PDF) (1 pg, 90K) |
Perfluorinated Aliphatic Carboxylic Acid, Ammonium Salt | Confidential | Confidential | Results of a chronic Daphnia magna study | |
| 8EHQ-1208-16778B (PDF) (142 pp, 9.13MB) |
Trimethylsilanol | 1066-40-6 | N | Silicones Environmental Health and Safety Council | Results of a 2-week whole-body inhalation toxicity range-finder study in albino rats and 28-day whole-body repeated dose inhalation toxicity study with reproductive/ developmental screening in albino rats |
| 8EHQ-1208-17079D (PDF) (2 pp, 548K) |
Sepiolite Nanoclay - Organically Modified Hydrated Magnesium Silicate | None | DuPont Haskell Laboratory | Response to the Agency's request for a complete report of pulmonary bioassay screening study | |
| Sepiolite - Hydrated Magnesium Silicate | 63800-37-3 | N | |||
| 8EHQ-1208-17187B (PDF) (3 pp, 196K) |
Triethoxyoctylsilane | 2943-75-1 | Y | Silicones Environmental Health and Safety Council (SEHSC) | Information concerning an combined oral (gavage) repeated dose toxicity study with a reproductive -developmental toxicity screening test in rats. |
| 8EHQ-1208-17277B (PDF) (1 pg, 44K) |
Crude Oil | Confidential | Confidential | A letter stating the sponsor's relinquishment of the confidentiality claim regarding the chemical substance identity for crude oil (8EHQ-08-17277A). |
(A) PMN; (B) Pesticide; (C) Pesticide Inert
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and
year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter
( “A” for the initial
submission and “B”, “C”, “D”, etc. for
supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the
same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to
request a copy of a submission.
FYI (For Your
Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is
similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter
either judges that the information is not reportable under TSCA 8(e) reporting
requirements or is not subject to TSCA 8(e) reporting but wants to share the
information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other
EPA programs and other federal agencies can ask OPPT to request follow-up
information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI"
indicates that the submitter is claiming the identity of the chemical to be
confidential business information. This claim can be challenged in some cases,
and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture
and importation. EPA defines high production volume as annual production one
million pounds or more pounds.
Description - A general description of the type of study or information submitted,
but not study results. A PDF electronic copy of the submission is attached.