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8(e) and FYI Submissions Received July 2008
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8EHQ# |
CHEM NAME(S) |
CAS NO.(S) |
USHV |
SUBMITTER |
DESCRIPTION |
| 8EHQ-0708-17191A (PDF) (2 pp, 85K) |
alkylazine | Confidential | Bayer CropScience LP | Results of an acute inhalation study in rats. | |
| 8EHQ-0708-17192A (PDF) (2 pp, 90K) |
Arylimine | Confidential | Bayer CropScience LP | Results of a range-finding oral (gavage) developmental toxicity study in rats. | |
| 8EHQ-0708-17193A (PDF) (2 pp, 85K) |
sulfonylurea | Confidential | Bayer CropScience LP | Results of a range-finding oral (gavage) developmental toxicity study in rabbits. | |
| 8EHQ-0708-17194A (PDF) (2 pp, 86K) |
Sulfonylurea | Confidential | Bayer CropScience LP | Results of a range-finding oral developmental toxicity study in rats. | |
| 8EHQ-0708-17195A (PDF) (2 pp, 87K) |
alkykazine | Confidential | Bayer CropScience LP | Results of an acute oral neurotoxicity study in rats. | |
| 8EHQ-0708-17196A (PDF) (29 pp, 1.05MB) |
1,3-diphenyl-1,2,3 propanetrione-2-[O(ethyoxycarbonyl)oxime] | 111451-23-1 | N | Center for Regulatory Services, Inc. | Results of an acute immobilization test in water fleas, algae growth inhibition test and fish acute toxicity test. |
| 8EHQ-0708-17197A (PDF) (1 pg, 45K) |
isoxazole, substituted | Confidential | Syngenta Crop Protection Inc. | Insufficient information to identify study. One animal had to be killed on day 3 for humane reasons. | |
| 8EHQ-0708-17198A (PDF) (51 pp, 867K) |
aliphatic, aromatic, unsaturated bicyclic derivative | Confidential | Keller and Heckman LLP | Preliminary results from a combined 90-day oral (gavage) repeated-dose and a one-generation reproductive toxicity study in rats. | |
| 8EHQ-0708-17199A (PDF) (1 pg, 38K) |
Oxime carbamate 7-2A | Confidential | CBI | Results of an acute oral (gavage) toxicity screen in rats. | |
| 8EHQ-0708-17200A (PDF) (1 pp, 38K) |
Oxime carbamate 7-2B | Confidential | CBI | Results of an acute oral (gavage) toxicity screen in rats. | |
| 8EHQ-0708-17201A (PDF) (1 pg, 37K) |
Oxamimidic acid, N[(methylcarbamoyl) oxy]- 1thio-, propyl ester |
24944-50-1 | N | CBI | Results of an acute oral (gavage) toxicity screen in rats. |
| 8EHQ-0708-17202A (PDF) (1 pg, 36K) |
Ethanimidothioic acid, N, N'[dithiobis[(methylimino)car bonyloxy]]bis[2(dimethylamino)- 2-oxo-, dimethyl ester | 71066-17-6 | N | CBI | Results of an acute oral (gavage) toxicity screen in rats. |
| 8EHQ-0708-17203A (PDF) (1 pg, 36K) |
Ethanimidothioic acid, N,N'[thiobis[(methylimino)carb onyloxy]]bis[2(dimethylamino)- 2-oxo-, dimethyl ester |
63942-44-9 | N | CBI | Results of an acute oral toxicity study in rats. |
| 8EHQ-0708-17204A (PDF) (1 pg, 35K) |
Oxime Carbamate 7-2C | Confidential | CBI | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0708-17205A (PDF) (4 pp, 210K) |
2,3,7,8-tetrachlorodibenzop- dioxin (TCDD) 2,3,4,7,8 pentachlorodibenzofuran (4-PeCDF) 2,3,7,8 tetrachlorodibenzofuran (TCDF) |
1746-01-6 57117-31-4 51207-31-9 |
N N N |
Dow Chemical Company | Results of egg injection and CYP1A1 induction studies in chicken and japanese quail. |
| 8EHQ-0708-17206A (PDF) (2 pp, 85K) |
Substituted Cyclopropanecarboxylate Family: Pyrethroide | Confidential | BASF Corporation | Results of an acute eye irritation test in rabbits. | |
| 8EHQ-0708-17207A (PDF) (1 pg, 53K) |
5-phenyl-pyrimidine derivative | None | BASF Chemical Company | Results of an acute oral (gavage) toxicity study in rats. | |
| 8EHQ-0708-17209A (PDF) (7 pp, 278K) |
experimental pyrethroid insecticide | Confidential | CBI | Results of an acute inhalation toxicity study in rats, a preliminary developmental toxicity study in rats and a micronucleus study in rats. | |
| 8EHQ-0708-17212A (PDF) (285 pp, 7.17MB) |
Soybean oil, sulfurized | 68152-90-9 | N | Lubrizol | Report of a combined systemic and reproduction repeated-dose oral gavage study in rats. |
| 8EHQ-0708-17213A (PDF) (2 pp, 80K) |
substituted nitrogen containing heterocycle (Substance A) and (Substance B) | Confidential | BASF Corporation | Results of screening tests on acute toxicity in water fleas. | |
| 8EHQ-0708-17214A (PDF) (2 pp, 93K) |
Nitrogen Containing Heterocycle *2 Substituted Epoxide *2 | Confidential Confidential | BASF Corporation | Results of the effect on growth of green algae. | |
| 8EHQ-0708-17215A (PDF) (2 pp, 92K) |
Nitrogen Containing Heterocycle *2 | Confidential | BASF Corporation | Results of a study on the growth of green algae. | |
| 8EHQ-0708-17216A (PDF) (2 pp, 74K) |
Substituted Nitrogen containing heterocycle | Confidential | BASF Corporation | Results of a test on acute toxicity in fathead minnow. | |
| 8EHQ-0708-17217A (PDF) (1 pg, 44K) |
imidazole, substituted | Confidential | Syngenta Crop Protection Inc. | Results of an acute oral toxicity study in rats | |
| 8EHQ-0708-17218A (PDF) (1 pg, 43K) |
Imidazole, substituted | Confidential | Syngenta Crop Protection, Inc. | Results of an acute oral toxicity study in rats | |
| 8EHQ-0708-17219A (PDF) (2 pp, 85K) |
Methylaminoethanol | 109-83-1 | Y | American Chemistry Council | Results of an oral gavage developmental toxicity range finding study in rats |
| 8EHQ-0708-17220A (PDF) (2 pp, 82K) |
Alkylazine | Confidential | Bayer CropScience LP | Results of a two generation reproductive toxicity study in rats | |
| 8EHQ-0708-17221A (PDF) (2 pp, 75K) |
(2,3,5,6 tetrafluorophenyl)methyl (1R-trans)-3-(2,2 dichloroethenyl)-2,2 dimethylcyclopropanecarbo xylate | 118712-89-3 | N | Bayer CropScience LP | Results of a chronic toxicity and carcinogenicity study in rats |
| 8EHQ-0708-17222A (PDF) (5 pp, 209K) |
N,N-dimethylaminoethanol | 108-01-0 | Y | BASF Corporation | Results of a modified developmental screening study in rats |
| 8EHQ-0708-17223A (PDF) (1 pg, 43K) |
imidazole, substituted | Confidential | Syngenta Crop Protection, Inc. | Results of an acute oral toxicity study in rats | |
| 8EHQ-0708-17224A (PDF) (1 pg, 46K) |
imidazole, substituted | Confidential | Syngenta Crop Protection, Inc. | Results of an acute oral toxicity study in rats | |
| 8EHQ-0708-17225A (PDF) (1 pg, 46K) |
pyrazole, substituted | Confidential | Syngenta Crop Protection Inc. | Results of a carcinogenicity study | |
| 8EHQ-0708-17226A (PDF) (2 pp, 103K) |
Diamylamine | 2050-92-2 | Y | American Chemistry Council | Results of a combined oral repeated dose/reproduction/developmental toxicity screening test in rats |
| 8EHQ-0708-17227A (PDF) (1 pg, 43K) |
imidazole, substituted | Confidential | Syngenta Crop Protection, Inc | Results of an acute oral toxicity study in rats | |
| 8EHQ-0708-17228A (PDF) (6 pp, 329K) |
Coke (Petroleum) | 64741-79-3 | Y | American Petroleum Institute | Results of an inhalation reproductive/developmental study in rats |
| 8EHQ-0708-15412C (PDF) (2 pp, 80K) |
1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,1 0,10-heptadecafluoro- | 678-39-7 | N | DuPont Haskell | Results of an inhalation metabolism study in rats |
| 8EHQ-0708-16105J (PDF) (2 pp, 78K) |
Thiophene derivative, substituted | None | DuPont Haskell | Results of a range-finding study in rats to determine doses for a definitive developmental neurotoxicity study. | |
| 8EHQ-0708-16105K (PDF) (1 pg, 42K) |
Thiophene derivative, substituted | Confidential | Dupont Haskell | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0708-16105L (PDF) (2 pp, 90K) |
Thiophene derivative, substituted | None | Dupont Haskell | Results of a 4 week immunotoxicity study in mice. | |
| 8EHQ-0708-16105M (PDF) (1 pg, 38K) |
Thiophene derivative, substituted | confidential | DuPont Haskell Laboratory | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0708-16365B (PDF) (2 pp, 85K) |
N-methyl(amino,chloro,methyl) carbomonocyclic carbamide | Confidential | CBI | Results of an in vivo micronucleus assay in mice. | |
| 8EHQ-0708-16630B (PDF) (1 pg, 63K) |
Bisphenol A-diglycidyl ether methacrylate | 1565-94-2 | N | 3M Company | Results of an oral repeated-dose toxicity study and a reproductive toxicity study in mice. |
| 8EHQ-0708-16819D (PDF) (2 pp, 65K) |
Halogenated pyridine derivative | Confidential | Dow Chemical Company | Results of an oral developmental toxicity study in rats. | |
| 8EHQ-0708-16913C (PDF) (1 pg, 64K) |
Fluorinated Aliphatic Alcohol | Confidential | CBI | Results of a developmental toxicity study in rats. | |
| 8EHQ-0708-16913D (PDF) (1 pg, 52K) |
Fluorinated Aliphatic Alcohol | Confidential | CBI | Results of an oral reproductive toxicity study in rats. | |
| 8EHQ-0708-16946C (PDF) (28 pp, 840K) |
Polymeric MDI | Confidential | CBI | Results of a modified local lymph node assay in mice. | |
| 8EHQ-0708-17045D (PDF) (1 pg, 60K) |
Perfluorinated Aliphatic Carboxylinc Acid | Confidential | CBI | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0708-17130B (PDF) (49 pp, 1.95MB) |
1-Chlorododecane | 112-52-7 | Y | Lonza Inc. | Final report of an in vitro mammalian chromosome aberration test in chinese hamster ovary cells. |
| FYI-0708-01611A (PDF) (63 pp, 5.80MB) |
multiwalled carbon nanotubes (MWNT) | None | Technology Sciences Group Inc. | Results of study exposing the mesothelial lining of the body cavity by i.p. injection of mice to MWNT. |
(A) PMN; (B) Pesticide; (C) Pesticide Inert
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and
year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter
( “A” for the initial
submission and “B”, “C”, “D”, etc. for
supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the
same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to
request a copy of a submission.
FYI (For Your
Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is
similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter
either judges that the information is not reportable under TSCA 8(e) reporting
requirements or is not subject to TSCA 8(e) reporting but wants to share the
information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other
EPA programs and other federal agencies can ask OPPT to request follow-up
information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI"
indicates that the submitter is claiming the identity of the chemical to be
confidential business information. This claim can be challenged in some cases,
and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture
and importation. EPA defines high production volume as annual production one
million pounds or more pounds.
Description - A general description of the type of study or information submitted,
but not study results. A PDF electronic copy of the submission is attached.