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Section 8(e) Substantial Risk Notifications and FYI Submissions Received June 2008

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0608-17169A (PDF)
(2 pp, 99K)
Steric hindered amin Confidential   BASF Corporation Interim results of an oral (gavage) prenatal developmental toxicity study in rats.
8EHQ-0608-17170A (PDF)
(3 pp, 131K)
Cyclopropanecarboxylate, substituted *2 Confidential N BASF Corporation Results of an acute toxicity study in fathead minnow.
Dinitrile, mixture *2 Confidential N
8EHQ-0608-17174A (PDF)
(2 pp, 94K)
triphenylboron (TPB) 960-71-4 Y Invista Draft results from a combined oral (gavage) repeated-dose toxicity study with a reproduction/ developmental toxicity screening test in rats.
8EHQ-0608-17175A (PDF)
(12 pp, 350K)
Sulfonium compound Confidential   Center of Regulatory Services, Inc. Results of an acute oral (gavage) toxicity study in rats.
8EHQ-0608-17176A (PDF)
(4 pp, 296K)
Octamethyltrisiloxane 107-51-7 N Silicones Environmental Health and Safety Council Results of a combined repeated-dose inhalation toxicity study with a reproductive/developmental toxicity screening test in rats.
8EHQ-0608-17177A (PDF)
(1 pg, 56K)
Allyl alcohol *3 107-18-6 Y LyondellBasell Industries Results of an acute inhalation (whole body) toxicity study in rats.
8EHQ-0608-17178A (PDF)
(3 pp, 137K)
Dimethyl-aminopropylolicacid-amid 109-28-4 N BASF Corporation Results of an oral (gavage) toxicity study in rats.
8EHQ-0608-17179A (PDF)
(3 pp, 105K)
Nitrogen containing heterocycle, substituted *2 Confidential BASF Corporation Results of screening tests on acute toxicity in Daphnia magna.
Cyclopropanecarboxylate, substituted (substance A and B) *2 Confidential
8EHQ-0608-17180A (PDF)
(3 pp, 131K)
Nitrogen containing heterocycle, substituted (SUBSTANCE A) *2 Confidential BASF Corporation Results of a study testing the effects on growth in aquatic plants.
Nitrogen containing heterocycle, substituted (SUBSTANCE B) Confidential
Chloro-acetic acid amide, substituted *2 Confidential
8EHQ-0608-17181A (PDF)
(29 pp, 1.55MB)
1,1,1,2,2,3,3-heptafluoro-3methoxypropane 375-03-1 N 3M Company Results of an acute toxicity study in Daphnia magna.
8EHQ-0608-17182A (PDF)
(21 pp, 1.13MB)
Ethylene oxide 75-21-8 Y Dow Chemical Company Copy of a 15 year update to a mortality study on worker exposure published in 1990 with a 10 year update published in 1993.
8EHQ-0608-17183A (PDF)
(2 pp, 73K)
5-amino-1-[2,6-dichloro-4(trifluoromethyl)phenyl]-4(ethylsulfinyl)-1Hpyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of a 28-day oral (dietary) toxicity study in rats.
8EHQ-0608-17184A (PDF)
(2 pp, 69K)
5-amino-1-[2,6-dichloro-4(trifluoromethyl)phenyl]-4(ethylsulfinyl)-1Hpyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of a 90-day oral (dietary) toxicity study in rats.
8EHQ-0608-17185A (PDF)
(244 pp, 5.72MB)
acryloylisocyanate or AOI Confidential ENVIRON International Corporation Results of a 4-week repeated-dose oral (gavage) toxicity study in rats.
8EHQ-0608-17186A (PDF)
(2 pp, 88K)
Cobalt monoxide 1307-96-6 N Cobalt Development Institute Results of anin vivo mammalian bone marrow chromosome aberration test in rats (oral).
Cobalt sulfate heptahydrate 10026-24-1 N
8EHQ-0608-17187A (PDF)
(3 pp, 191K)
Triethoxyoctylsilane 2943-75-1 Y Silicones Environmental Health and Safety Council Results of a combined oral (gavage) repeated-dose toxicity study with a reproductive/ developmental toxicity screening test in rats for 28-42 consecutive days.
8EHQ-0608-17188A (PDF)
(2 pp, 92K)
2,2-Bis(t-butylperoxy isppropyl)benzene 25155-25-3 Y Akzo Nobel Polymer Chemicals, LLC Results of a reproductive oral (gavage) toxicity study in rats for 14 or 44 days.
8EHQ-0608-17189A (PDF)
(3 pp, 111K)
Nitrogen containing heterocycle, substituted *2 Confidential BASF Corporation Results of an oral (gavage) prenatal developmental toxicity study in rats.
8EHQ-0608-17190A (PDF)
(2 pp, 65K)
Dinitrile Confidential BASF Corporation Results of an acute oral (drinking water) toxicity study in rats.
8EHQ-0608-00373CN (PDF)
(2 pp, 84K)
perfluorohexane sulfonate (PFHS) None 3M Company Supplemental information regarding sampling activities from a site-related environemntal assessment of fluorochemcials for the 3M Decatur, Alabama manufacturing facility. Reports included data on PFOA, PFBS, PFHS and PFOS. Reports contain off-site data froma re-sampling of a groundwater monitoring well.
perfluorooctane sulfonate (PFOS) None
8EHQ-0608-00373CN (PDF)
(2 pp, 84K)
perfluorooctanoate (PFOA) None 3M Company Supplemental information regarding sampling activities from a site-related environemntal assessment of fluorochemcials for the 3M Decatur, Alabama manufacturing facility. Reports included data on PFOA, PFBS, PFHS and PFOS. Reports contain off-site data froma re-sampling of a groundwater monitoring well.
perfluorobutane sulfonate (PFBS) None
8EHQ-0608-00373CO (PDF)
(2 pp, 97K)
perfluorobutane sulfonate (PFBS) None 3M Company Two final reports on the analysis of sulfonate-based and carboxylate-based fluorochemicals found at 3M Decatur site: (1) MPI Project Number: P0001131, Interim Report #6-- Analysis of Liver and Serum Samples: Analysis of perfluorobutane (PFBS), perfluorohexane sulfonate (PFHS), and perfluorooctane sulfonate (PFOS) in water, soil, sediment, fish, clams, vegetation, small mammal liver and small mammal serum using LC/MS/MS for the 3M Decatur monitoring progam: and (2) Exygen Study No. P0001131, Interim Report #12-- Analysis of Vegetation Samples: (same description and chemicals as above)
perfluorohexane sulfonate (PFHS) None
Perfluorooctane sulfonate None
8EHQ-0608-16446F (PDF)
(12 pp, 324K)
perfluorooctanoic acid (PFOA) None DuPont Haskell Laboratory Occupational serum sampling results for workers at a DuPont site.
8EHQ-0608-16663C (PDF)
(13 pp, 437K)
perfluorooctanoic acid (PFOA) None DuPont Haskell Laboratory Occupational serum sampling results for workers at a DuPont site.
8EHQ-0608-16819C (PDF)
(2 pp, 80K)
Halogenated pyridine derivative Confidential Dow Chemical Company Results from an acute oral (gavage) toxicity study in rats and mice and an acute oral (gavage) neurotoxicity probe study in rats.
8EHQ-0608-16907B (PDF)
(3 pp, 205K)
ethaneperoxoic acid, 1,1diemthylethyl ester 107-71-1 Y Akzo Nobel Polymer Chemicals, LLC. Results of a combined oral (gavage) repeated-dose toxicity study with a reproductive/ developmental toxicity screening test in rats.
8EHQ-0608-16916E (PDF)
(1 pg, 38K)
ammonium salt of fluoroalkyl carboxylic acid Confidential CBI Results of a 24-hour semi-occluded acute dermal toxicity study in rats.
8EHQ-0608-17102B (PDF)
(2 pp, 103K)
Confidential Confidential CBI Preliminary data from an ongoing oral toxicity study in rats.
8EHQ-0608-17109B (PDF)
(2 pp, 119K)
Multi-walled carbon nanotubes *3 7782-42-5 N U.S. EPA Request for additional information regarding test susbtance characterization protocols.

(1) PMN; (2) Pesticide; (3) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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