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Section 8(e) Substantial Risk Notifications and FYI Submissions Received May 2008

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0508-17138A (PDF)
(1 pg, 49K)
Metal working fluid containing 3-amino-4-octanol 1001354-72-8 N Dow Chemical Company Report of mortality following dermal exposure to an unspecified species.
8EHQ-0508-17139A (PDF)
(2 pp, 119K)
Methane sulfinic acid, hydroxy-, monosodium salt *3 149-44-0 Y Synthetic Organic Chemical Manufacturers Association (SOCMA) Results of a micronucleus test in mice.
8EHQ-0508-17140A (PDF)
(2 pp, 63K)
Poly(oxy-1,2-ethanediyl),alpha-isotridecyl-omega-methoxy- 345642-79-7 N Bayer CropScience LP Results of a pilot dose range-finding study for a combined repeated-dose toxicity study with a reproduction/developmental toxicity screening test in an unspecified species.
8EHQ-0508-17141A (PDF)
(2 pp, 58K)
Carboxamide Confidential   Bayer CropScience LP Results of a 90-day dietary toxicity study in dogs.
8EHQ-0508-17142A (PDF)
(2 pp, 66K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of an acute oral neurotoxicity study in rats.
8EHQ-0508-17143A (PDF)
(2 pp, 63K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of an oral dose range-finding neurotoxicity study in rats.
8EHQ-0508-17144A (PDF)
(2 pp, 61K)
Benzamide Confidential   Bayer CropScience LP Results of an oral range-finding developmental study in rabbits.
8EHQ-0508-17145A (PDF)
(2 pp, 52K)
Benzamide Confidential   Bayer CropScience LP Results of an oral (gavage) developmental toxcity study in rats.
8EHQ-0508-17146A (PDF)
(1 pg, 57K)
t-Butyl acetate 540-88-5 N Lyondell Chemical Company Results of an oral developmental toxicity study in rats.
8EHQ-0508-17147A (PDF)
(1 pg, 46K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results of a 28-day repeated-dose toxicity study in rats.
8EHQ-0508-17148A (PDF)
(1 pg, 49K)
Confidential Confidential   Syngenta Crop Protection, Inc. Results of an acute oral neurotoxicity study in rats.
8EHQ-0508-17149A (PDF)
(80 pp, 2.28MB)
4,4'-Methylenedianiline
101-77-9 Y American Chemistry Council Diisocyanates Panel Final reports of an acute and a chronic toxicity study in Daphnia magna.
8EHQ-0508-17150A (PDF)
(1 pg, 59K)
Fluorochemicals Confidential   Confidential Results of an acute toxicity study in Daphnia magna and an acute oral toxicity study in female rats.
8EHQ-0508-17151A (PDF)
(3 pp, 138K)
Alkyl ammonium chloride salts 70750-47-9 N Exponent Results of a combined repeated-dose/reproductive/developmental toxicity study in rats.
8EHQ-0508-17152A (PDF)
(7 pp, 286K)
Nickel metal powder 7440-02-0 N Nickel Producers Environmental Research Association Results of a whole-body inhalation carcinogenicity study in rats.
8EHQ-0508-17153A (PDF)
(2 pp, 55K)
Benzamide Confidential   Bayer CropScience LP Results of an oral (dietary) 14-day mechanistic toxicity study in mice.
8EHQ-0508-17154A (PDF)
(2 pp, 63K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of a 14-day oral repeated-dose study examining the biliary excretion and pharmacokinetics of 125I-Thyroxine (T4) in male rats.
8EHQ-0508-17155A (PDF)
(3 pp, 138K)
9-Octadecenoic acid (Z)-, reaction products with 2-[(2-aminoethyl)amino]ethanol, propoxylated 93925-18-9 N BASF Corporation Results of a modified oral developmental toxicity study in rats.
8EHQ-0508-17156A (PDF)
(3 pp, 147K)
Octanoic acid chloride 111-64-8 N BASF Corporation Results of an acute inhalation toxicity study in rats.
8EHQ-0508-17157A (PDF)
(2 pp, 88K)
Dinitrile *2 Confidential   BASF Corporation Results of a 96-hour toxicity screening test in fish.
Substance B *2 Confidential  
8EHQ-0508-17158A (PDF)
(2 pp, 63K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of an oral (dietary) chronic toxicity and carcinogenicity study in rats.
8EHQ-0508-17159A (PDF)
(2 pp, 66K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of an oral (gavage) developmental toxicity study in rabbits.
8EHQ-0508-17160A (PDF)
(2 pp, 80K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of a range-finding two generation reproductive toxicity study in rats.
8EHQ-0508-17161A (PDF)
(2 pp, 73K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of an oral (gavage) developmental toxicity study in rabbits.
8EHQ-0508-17162A (PDF)
(2 pp, 70K)
5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile 181587-01-9 N Bayer CropScience LP Results of a range-finding oral (gavage) developmental toxicity study in rats.
8EHQ-0508-17163A (PDF)
(2 pp, 84K)
C8-C18 Fatty amines and amine acetate salts 61788-46-3 Y Exponent, Inc. Preliminary results of a conbined oral repeated-dose toxicity study with reproductive/developmental toxicity screen in rats.
8EHQ-0508-17164A (PDF)
(7 pp, 345K)
Ink Coating Formulation Confidential   Confidential Results of an acute aquatic toxicity study in rainbow trout.
8EHQ-0508-17165A (PDF)
(1 pg, 48K)
Fluorochemical Confidential   Confidential Results of an acute oral toxicity study in rats
8EHQ-0508-17166A (PDF)
(1 pg, 38K)
Isocyanate, blocked aromatic Confidential   Confidential Results of an acute oral toxicity study in rats
8EHQ-0508-17167A (PDF)
(3 pp, 154K)
Perhydrogenated 9-ethylcarbazole 146900-30-3 N Confidential Results of an acute oral toxicity study in rats and skin irritation study in rabbits.
8EHQ-0508-17168A (PDF)
(2 pp, 87K)
Alcohols, C12-14-secondary, ethoxylated 84133-50-6 Y Exponent, Inc. Results of a reproductive/ developmental toxicity study in rats (route not specified).
8EHQ-0508-17171A (PDF)
(1 pg, 50K)
Confidential Confidential   Syngenta Crop
Protection, Inc.
Results from 2 acute oral toxicity/ toxicokinetic studies in the rat.
8EHQ-0508-17172A (PDF)
(2 pp, 55K)
Confidential Confidential   Syngenta Crop
Protection, Inc.
Results from a 4-week dietary study in the rat.
8EHQ-0508-17173A (PDF)
(1 pg, 51K)
Confidential Confidential   Syngenta Crop
Protection, Inc.
Results from a dose range-finding prenatal developmental toxicity study in the New Zealand White rabbit.
8EHQ-0508-02267I (PDF)
(2 pp, 71K)
Confidential Confidential   DuPont Haskell Global Centers for Health and Environmental Sciences Results for two 28-day dietary repeated-dose toxicity studies in rats.
8EHQ-0508-16391C (PDF)
(1 pg, 54K)
Copper hydroxide *3 20427-59-2 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute oral toxicity study in rats.
8EHQ-0508-16436F (PDF)
(3 pp, 197K)
Perfluorinated aliphatic carboxylic acid, ammonium salt Confidential N Confidential Results of a 28-day oral (gavage) repeated-dose toxicity study in rats and mice.
8EHQ-0508-16478F (PDF)
(3 pp, 201K)
Perfluorinated aliphatic carboxylic acid, ammonium salt Confidential N Confidential Results of a 28-day oral (gavage) repeated-dose toxicity study in rats and mice.
8EHQ-0508-16640C (PDF)
(1 pg, 37K)
Acrylonitrile 107-13-1 N DuPont Haskell Global Centers for Health and Environmental Sciences Supplemental information regarding the publication of a manuscript submitted to EPA.
8EHQ-0508-16908B (PDF)
(3 pp, 141K)
Hexaneperoxoic acid, 2-ethyl, 1,1-dimethylethyl ester 3006-82-4 Y Azko Nobel Polymer Chemicals, LLC Results of an oral (gavage) reproductive/developmental toxicity study in rats.
8EHQ-0508-16946B (PDF)
(2 pp, 70K)
Confidential Confidential   U.S. EPA Request from EPA for complete report entitled 'Local Lymph Node Assay in Mice'.
8EHQ-0508-16985C (PDF)
(1 pg, 73K)
Pyrimidine, substituted Confidential N Confidential Results of a two-generation dietary reproductive toxicity study in rats.
8EHQ-0508-17009B (PDF)
(34 pp, 1.22MB)
Triisobutyl (methyl) phosphonium toluenesulfonate 344744-05-6 N Confidential Final reports of an acute eye irritation study in rabbits and a dermal sensitization study (local lymph node assay) in mice.
8EHQ-0508-17045C (PDF)
(1 pg, 66K)
CN-2065 *1 Confidential N Confidential Results of an acute oral toxicity study in rats.
8EHQ-0508-17083B (PDF)
(3 pp, 124K)
CN-2065 *1 Confidential   Great Lakes Chemical Corporation Supplemental documentation for confidentiality claim.
8EHQ-0508-17127B (PDF)
(3 pp, 120K)
CN-2065 *1 Confidential   Great Lakes Chemical Corporation Supporting information for confidentiality substantiation.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial
submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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