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Section 8(e) Substantial Risk Notifications and FYI Submissions Received May 2009

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0509-13171A (PDF)
(2 pp, 102K)
2-Amino-2-methylpropanenitrile 19355-69-2 Y DuPont Haskell Global Centers Results of a combined repeated dose toxicity study in rats with a reproduction/developmental toxicity screening test.
8EHQ-0509-17399A (PDF)
(533 pp, 10.29MB)
Tertiary butyl alcohol *3 75-65-0 Y Lyondell Chemical Company Final report of a 14-day oral (drinking water) toxicity study in mice.
8EHQ-0509-17504A (PDF)
(2 pp, 103K)
Fluoroalkyl phosphoryl chloride Confidential   Confidential Results of an acute oral toxicity study in rats and mice.
8EHQ-0509-17505A (PDF)
(2 pp, 64K)
Mixture of substituted isothiazolone and solvent Confidential   Confidential Effects from an acute toxicity study in fish.
8EHQ-0509-17506A (PDF)
(2 pp, 62K)
Mixture of substituted isothiazolone and solvent Confidential   Confidential Effects from an aquatic toxicity study in green algae.
8EHQ-0509-17507A (PDF)
(1 pg, 56K)
Confidential Confidential   Confidential Results of an acute toxicity study in Daphnia magna.
8EHQ-0509-17508A (PDF)
(2 pp, 84K)
Nitrogen containing heterocycle Confidential BASF Corporation Results of an acute eye irritation test in rabbits.
8EHQ-0509-17509A (PDF)
(2 pp, 80K)
Nitrogen containing heterocycle *2 Confidential BASF Corporation Results of a 12-month dietary toxicity study in Beagle dogs.
8EHQ-0509-17510A (PDF)
(2 pp, 121K)
Phenyl substituted aldehyde Confidential Confidential Preliminary results from a 14-day oral toxicity study in rats.
8EHQ-0509-17511A (PDF)
(2 pp, 126K)
Hydrocarbon aldehyde Confidential Confidential Preliminary results from a 14-day oral toxicity study in rats.
8EHQ-0509-17512A (PDF)
(2 pp, 68K)
Confidential Confidential Confidential Results of an acute inhalation toxicity study in rats.
8EHQ-0509-17513A (PDF)
(1 pg, 57K)
Ethyl urea 625-52-5 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a pre-1977 (1974) acute oral toxicity study in rats.
8EHQ-0509-17514A (PDF)
(1 pg, 80K)
Nitrogen containing heterocycle, substituted Confidential Confidential Results of an in vivo mouse micronucleus assay.
8EHQ-0509-17515A (PDF)
(1 pg, 53K)
Nitrogen containing heterocycle, substituted Confidential Confidential Results of an acute algal assay.
8EHQ-0509-17516A (PDF)
(1 pg, 66K)
1,1,2,3,3,3-Hexafluoropropyl2,2,2-trifluoroethyl ether 993-95-3 N 3M Corporation Preliminary data from an acute inhalation toxicity study in rats.
8EHQ-0509-17517A (PDF)
(2 pp, 90K)
Poly[oxy(methyl-1,2-ethanediyl)],.alpha.-butyl-.omega.-hydroxy- *3 9003-13-8 N Dow Chemical Company Results of a 23-day preliminary oral dose range-finding study in rats.
8EHQ-0509-17518A (PDF)
(1 pg, 53K)
Amide mixture Confidential Confidential Results of an acute oral toxicity study in rats.
8EHQ-0509-17519A (PDF)
(1 pg, 57K)
Petroleum distillates, aromatic acid and aromatic compound mixture Confidential Confidential Results of an acute oral and an acute inhalation toxicity study in rats.
8EHQ-0509-17520A (PDF)
(1 pg, 62K)
Petroleum distillates and aromatic acid mixture Confidential Confidential Results of an acute oral toxicity study in rats.
8EHQ-0509-17521A (PDF)
(2 pp, 84K)
Formyloxymandeloyl chloride 29169-64-0 DuPont Haskell Global Centers for Health and Environmental Sciences Results of an eye irritation test, skin irritation test and an acute inhalation toxicity study.
8EHQ-0509-17522A (PDF)
(1 pg, 59K)
Amine and amide mixture Confidential Confidential Results of an acute oral toxicity study in rats.
8EHQ-0509-17523A (PDF)
(1 pg, 72K)
Benzamine, 2,6-dimethyl- 87-62-7 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute dermal toxicity study in rabbits.
8EHQ-0509-17524A (PDF)
(1 pg, 66K)
Ethyl 4-nitrobenzoate 99-77-4 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute oral toxicity study in rats.
8EHQ-0509-17525A (PDF)
(2 pp, 84K)
Benzenamine, 2,4-dimethyl- 95-68-1 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an eye irritation test in rabbits and a skin sensitization study in guinea pigs.
8EHQ-0509-17526A (PDF)
(2 pp, 129K)
N,N-dimethyl-p-toluidine 99-97-8 Y DuPont Haskell Global Centers for Health and Environmental Sciences Results of an eye irritation test, skin irritation test, skin sensitization test, an acute oral toxicity study and a study to evaluate methemoglobin formation.
8EHQ-0509-17527A (PDF)
(1 pg, 58K)
Confidential Confidential   Confidential An acute oral toxicity study with Petroleum Distillates, Aromatic Acid, Aromatic Compound, and Glycol Ethers.
8EHQ-0509-17528A (PDF)
(1 pg, 56K)
Petroleum distillates, aromatic acid, aromatic compound and glycol ethers, mixture Confidential Confidential Results of an acute oral toxicity study in rats.
8EHQ-0509-17529A (PDF)
(2 pp, 117K)
N-ethyl-N-hydroxyethyl-m-toluidine 91-88-3 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute oral toxicity study, eye irritation test, skin sensitization test and an acute inhalation toxicity study.
8EHQ-0509-17530A (PDF)
(2 pp, 68K)
Perfluorohexanoate anion (PFHxA) 307-24-4 N DuPont Haskell Global Centers for Health and Environmental Sciences Results (2009) of serum sampling from workers at the Washington Works, Parkersburg, West Virginia facility.
8EHQ-0509-17531A (PDF)
(2 pp, 91K)
Pentanoic acid, nonafluoro 2706-90-3 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of acute toxicity studies in freshwater green algae and fathead minnows.
8EHQ-0509-17532A (PDF)
(1 pg, 62K)
Dimethyl (dehydrogenated tallow) (C16-C18) ammonium chloride (70% active ingredient in isopropyl alcohol) 61789-80-8 Y DuPont Haskell Global Centers for Health and Environmental Sciences Results of a pre-1977 (1968) acute oral toxicity study in rats.
8EHQ-0509-17533A (PDF)
(1 pg, 63K)
4-chloro-alpha-(1-methylethy1)-benzeneacetic acid-phenylethylamine None DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute oral toxicity study in rats.
8EHQ-0509-17534A (PDF)
(1 pg, 58K)
1 -(2-cyanoacetyl)-3-ethyl urea 41078-06-2 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a pre-1977 (1974) acute oral toxicity study in rats.
8EHQ-0509-17535A (PDF)
(2 pp, 110K)
Halogenated pentanol Confidential Confidential Results of pre-1977 acute oral, inhalation, and dermal toxicity studies as well as a screening study for anesthetic properties.
8EHQ-0509-17536A (PDF)
(21 pp, 675K)
Cardolite NC-513 epoxy diluent 171263-25-5 N Cardolite Corporation Results of a local lymph node assay in the mouse.
8EHQ-0509-15945V (PDF)
(2 pp, 113K)
Anthranilamide, substituted Confidential DuPont Haskell Global Centers for Health and Environmental Sciences Preliminary results of a 2-year feeding study in rats.
8EHQ-0509-16916F (PDF)
(2 pp, 118K)
Fluoroalkyl carboxylic acid, ammonium salt Confidential Confidential Preliminary results of a 7-day repeated-dose toxicity study in rats and mice.
8EHQ-0509-17279B (PDF)
(2 pp, 88K)
2-Propenoic acid, 2-methyl-, 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester 2144-53-8 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a repeated-dose oral toxicity study in rats.
8EHQ-0509-17323B (PDF)
(3 pp, 107K)
3-Nitro-4-octanol 252254-51-6 N Dow Chemical Company Response to a request by EPA regarding the correct CAS number for submission 8EHQ_1108_17323A
8EHQ-0509-17458B (PDF)
(1 pg, 48K)
2-Thiophenecarboxylic acid, 3-(isocyanatosulfonyl)-, methyl ester 79277-18-2 N DuPont Haskell Global Centers for Health and Environmental Sciences Response to EPA's request dated May 6, 2009 (received May 11, 2009) for the correct CAS
number of the test substance identified in the submitter's letter on March 26, 2009.
8EHQ-0509-17440B (PDF)
(3 pp, 199K)
Fluoroalkyl phosphoric acid salt, aqueous solution Confidential   Confidential Results of a repeated dose oral toxicity study in rats and mice.
8EHQ-0509-17450B (PDF)
(4 pp, 232K)
Dimethoxydimethylsilane 1112-39-6 N Silicones Environmental, Health and Safety Council (SEHSC) Histopathological findings from a combined repeated-dose toxicity study with a reproductive/ developmental screening test in rats.
8EHQ-0509-17458B (PDF)
(1 pg, 48K)
2-Thiophenecarboxylic acid, 3-(isocyanatosulfonyl)-, methyl ester 79277-18-2 N DuPont Haskell Global Centers for Health and Environmental Sciences Response to EPA's request dated May 6, 2009 (received May 11, 2009) for the correct CAS number of the test substance identified in the submitter's letter on March 26, 2009.
8EHQ-0509-17459B (PDF)
(2 pp, 102K)
Hydroxy-chloro-cyclopropyl-heteromonocycliccarboxylic acid Confidential   Confidential Results of an acute inhalation toxicity study and an oral developmental toxicity study in rats.
FYI-0509-01613 (PDF)
(79 pp, 1.60MB)
Sandospace S: Benzenesulfonic acid, 4-[[4-chloro-6-(1-methylethoxy)- l,3,5-
triazin-2-yl]amino]-, sodium salt (1:1)
68413-55-8 N Clariant Corporation Results of a guinea pig sensitization study and a human repeat insult patch test.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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