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Section 8(e) Substantial Risk Notifications and FYI Submissions Received November 2010

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1110-18162A (PDF) m-Xylylene diisocyanate 3634-83-1   Mitsui Chemicals America, Inc. Results of a Chromosomal Aberration Test Using Cultured Mammnalian Cells with m-Xylylene diisocyanate (XDI) (CASRN 3634-83-1)
8EHQ-1110-18167A (PDF) bis (2-hydroxyethyl) coco alkylamine 61791-31-9   Akzo Nobel Surface Chemistry LLC The results from an OECD 422 reproduction/developmental toxicity screening test on bis (2-hydroxyethyl) coco alkylamine, CAS# 61791-31-9.
8EHQ-1110-18168A (PDF) bis (2-hydroxyethyl) coco alkylamine 61791-31-9   Akzo Nobel Surface Chemistry LLC The results from an oral (gavage) fourteen day range-finding study in rats, with an initial assessment of the maximum tolerated dose, on bis (2-hydroxyethyl) coco alkylamine, CASRN 61791-31-9.
8EHQ-1110-18169A (PDF) Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)- 154279-60-4   DORF KETAL CHEMCALS LLC The results of two studies: (1) a study of the toxicity of Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)-, (ClearlinkŪ 1000) CASRN154279-60-4 to the freshwater green algae, Selenastrum capricornuaum and (2) a study of the toxicity of Clearlink100
8EHQ-1110-18170A (PDF) Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)- 154279-60-4   DORF KETAL CHEMCALS LLC The results of a toxicity test of Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)-, (ClearlinkŪ 1000) CASRN 154279-60-4 in rats by 28-day repeated oral administration. Dorf Ketal imports and distributes ClearlinkŪ 1000 in the United States.
8EHQ-1110-18171A (PDF) Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)- 154279-60-4   DORF KETAL CHEMCALS LLC The results of a skin sensitization study (local lymph node assay) of Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)-, (ClearlinkŪ 1000) CASRN 154279-60-4 in the mouse. Dorf Ketal imports and distributes Clearlink 1000 in the United States
8EHQ-1110-18172A (PDF) Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)- 154279-60-4   DORF KETAL CHEMCALS LLC The results of an acute oral toxicity study of Cyclohexanamine, 4,4'-methylenebis[N-(1 -methylpropyl)-, (ClearlinkŪ 1000) CASRN 154279-60-4.
8EHQ-1110-18173A (PDF) 2,5(or 2,16). bis-isocyanatomethyl-bicyclo[221]heptane 7409 1-64-8   MITSUI CHEMICALS AMERICA INC. The evaluation of the mutagenic activity of 2,5(or 2,16). Bis-isocyanatomethyl-bicyclo[221]heptane (CASRN 7409 1-64-8) in an in vitro mammalian cell gene mutation test with l51 78y mouse lymphoma cells.
8EHQ-1110-18174A (PDF) Aluminum tris dihydrogenphosphate 13530-50-2   ICL Performance Products, LP The results of an eye irritation study with Aluminum tris dihydrogenphosphate (CASRN 13530-50-2).
8EHQ-1110-18175A (PDF) Phosphoric acid, aluminum sodium salt 7785-88-8   ICL Performance Products, LP Results of an acute eye irritation study in rabbits with  Phosphoric acid, aluminum sodium salt (1:3:8) (CASRN 7785-88-8).
8EHQ-1110-18176A (PDF) Diphosphoric acid, sodium salt (1:4) 7722-88-5   ICL Performance Products, LP Results of an acute eye irritation study in rabbits with Diphosphoric acid, sodium salt (1:4) (CASRN 7722-88-5).
8EHQ-1110-18177A (PDF) Phosphoric acid, calcium salt (2: 1) 7758-23-8   ICL Performance Products, LP Results of an acute eye irritation study in rabbits with Phosphoric acid, calcium salt (2: 1) (CASRN 7758-23-8).
8EHQ-1110-18178A (PDF) Vanadium Pentoxide 1314-62-1   Vanadium Producers & Reclaimers Association (VPRA) Results of an acute inhalation study in mice with vanadium pentoxide (CASRN 1314-62-1).
8EHQ-1110-18179A (PDF) Dimethyl, (amninoethylaminopropyl) methyl siloxane and ctamethylcyclotetrasiloxane 71750-79-3 and 556-67-2   Dow Corning The results of the acute toxicity of Daphnia magna exposed to ZMAT Number 4054114 (Dimethyl, (amninoethylaminopropyl) methyl siloxane, CASRN 71750-79-3 >60.05 and ctamethylcyclotetrasiloxane, CASRN 556-67-2 1.0 =5.0%.
8EHQ-1110-18180A (PDF) Confidential *2 Not Availible   Confidential Results of a Toxicity Study on Green Alga (Pseudokirchneriella subcapitata) with the confidential submitted test substance.
8EHQ-1110-18181A (PDF) Confidential *2 Not Availible   Confidential Results of a repeated-dose range-finding study in wistar rats with the submitted confidential substance.
8EHQ-1110-18182A (PDF) 3-amino-7-(dimethylamino)-2-methoxyphenoxazin-5-ium chloride 67846-56-4   BASF Results of a repeated-dose range-finding study in wistar Rats with 3-amino-7-(dimethylamino)-2-methoxyphenoxazin-5-ium chloride (CASRN 67846-56-4).
8EHQ-1110-18183A (PDF) 1,3,5-tris(2-hydroxyethyl)-s-triazine 4719-04-4   BASF Results of an acute inhalation study in wistar rats with (hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine (CASRN 4719-04-4) as Liquid Aerosol.
8EHQ-1110-18184A (PDF) Tetrachloromethane 56-23-5   Arkema Inc. Results of the skin sensitization potential of tetrachloromethane (CASRN 56-23-5) in mice using Local Lymph Node Assay (LLNA).
8EHQ-1110-18185A (PDF) Adipic acid, bis[2-(2-butoxyethoxy)ethyl] ester, 141-17-3   American Chemistry Council (ACC) The results of an algal growth inhibiton test with adipic acid, bis[2-(2-butoxyethoxy)ethyl] ester, (CASRN: 141-17-3).
8EHQ-1110-18186A (PDF) Dibenzoyl peroxide 94-36-0   Arkema Inc. Results of an acute fish and algal toxicity studies with dibenzoyl peroxide (CASRN 94-36-0).
8EHQ-1110-18187A (PDF) Siloxanes and Silicones,
3-aminopropyl Me, di-Ph, polymers with Ph silsesquioxanes
1242619-23-3   Confidential Results of a fresh water algal test, Pseudokirchneriella subcapitata, with Siloxanes and Silicones,
3-aminopropyl Me, di-Ph, polymers with Ph silsesquioxanes (CASRN 1242619-23-3).
8EHQ-1110-18188A (PDF) Halogenated pyridine derivative Confidential   Dow Chemical Company Results of a repeated dose toxidity study in rats with halogenated pyridine derivative.
8EHQ-1110-18189A (PDF) Halogenated pyridine derivative Confidential   Dow Chemical Company The results of a dietary developemental toxicity study in rats with halogenated pyridine derivative
8EHQ-1110-18190A (PDF) 1-propanol, 2-(dimethylamino)-2-methyl-, and  1-Propanol, 2-(dimethylamino)-2-methyl-, hydrochloride 7005-47-2 and 10026-98-9   Dow Chemical Company The results of a non-standard in vivo reproductive toxicity screening probe study in rats with 1-propanol, 2-(dimethylamino)-2-methyl-, CASRN: 7005-47-2 and 1-Propanol, 2-(dimethylamino)-2-methyl-, hydrochloride -CASRN: 10026-98-9.
8EHQ-1110-18191A (PDF) Acryloyl chloride 814-68-6   3M Environmental, Heaalth and Safety Operations. The results of an acute inhalation toxicity study conducted in Sprague Dawley rats on CASRN 814-68-6, acryloyl chloride.
8EHQ-1110-18192A (PDF) Dibenzoyl peroxide 94-36-0   AkzoNobel The results from a series of aquatic studies conducted on dibenzoyl peroxide CASRN 94-36-0.
8EHQ-1110-18193A (PDF) Confidential Confidential   Confidential The results of an acute toxicity study in the water flea (Daphnia magna) with the submitted test substance.
8EHQ-1110-18194A (PDF) 2-propenoic acid, polymer with oxirane and 1 ,2,3-propanetriol 144086-03-3   BASF Results of an acute inhalation study in Wistar Rats with 2-propenoic acid, polymer with oxirane and 1 ,2,3-propanetriol (CASRN 144086-03-3) as liquid aerosol.
8EHQ-1110-18195A (PDF) (1 RS,5RS;l1RS,5SR)-5-(4-chlorobenzyl)-2,2-dimethyl-1 -(1 H-1,2,4-triazol-1 -ylmethyl)cyclopentanol and 2,4,5,6-tetrachloro-1,3- enzenedicarbonitrile. 125116-23-6 and  1897-45-6   BASF Results of an acute toxicity study in water flea (Daphnia magna) with a mixture containing two active ingredients; (1) (1 RS,5RS;l1RS,5SR)-5-(4-chlorobenzyl)-2,2-dimethyl-1 -(1 H-1,2,4-triazol-1 -ylmethyl)cyclopentanol (CASRN 125116-23-6) and
(2) 2,4,5,6
8EHQ-1110-18196A (PDF) isononyiphenol, diethanolamine and formaldehyde in TCPP Not Provided   Bayer Material Science LLC The results of a local lymph node Assay in mice to assess the dermal sensitization potential for the condensation productsof isononyiphenol, diethanolamine and formaldehyde in TCPP
8EHQ-1110-18198A (PDF) Confidential Confidential   Center for Regulatory Services, Inc. Results of an In vitro Micronucleus Test in Cultured Human Lymphocytes.
8EHQ-1110-15945AD (PDF) Not Provide Not Provided   DuPont Haskell Global Centers The results of an eighteen-month mouse study with the R&D test substance.
8EHQ-1110-16913G (PDF) 1-Octanol, 3,3,4,4, 5,5,6,6,7,7,8,8,8-tridecafluoro 647-42-7   DuPont Haskell Global Centers The results of a one-week inhalation study with 1-Octanol, 3,3,4,4, 5,5,6,6,7,7,8,8,8-tridecafluoro (CASRN 647-42-7)
8EHQ-1110-17229G (PDF) Perfluorooctanoate Anion (PFOA) Not Provided   DuPont Haskell Global Center Occupational PFOA serum sampling results for workers at the above referenced DuPont site for September 2010
8EHQ-1110-17365E (PDF) Octanoic acid, 4,4,5,5,6,6,7,7,8,8,8-undecafluoro- 14637-49-3   DUPont Haskell Global Centers Preliminary results of an ongoing repeated oral dose toxicity study in rats with Octanoic acid, 4,4,5,5,6,6,7,7,8,8,8-undecafluoro- (CASRN 9 14637-49-3)
8EHQ-1110-17774B (PDF) 2-(aminosulfonyl)-6-(trifluoromethyl)-, methyl 144740-59-0   DuPont Haskell Global Centers The results of a biodegradation test with 2-(aminosulfonyl)-6-(trifluoromethyl)-, methyl (CASRN 144740-59-0).
8EHQ-1110-18060B (PDF) Dimethyl, (aminoethylaminopropyl) methyl. Siloxane, Decamethylcyclopentasiloxane, Aminofunctional cyclosiloxanes, Octamethylcyclotetrasiloxane, Dimethylcyclosiloxanes 71750-79-3, 541-02-6, and 556-67-2)   Dow Corning Corporation Results of an acute toxicity study on Cladoceran (Daphnia magna) with ZMAT Number 4054113 (CASRN(s) 71750-79-3, 541-02-6, and 556-67-2).

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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