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Section 8(e) Substantial Risk Notifications and FYI Submissions Received April 2011

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0411-18297A (PDF) C-932 (Y-Oil)  Multiple   Hoechst Celanese Corporation Report on a two-week inhalation study in rats
8EHQ-0411-18298A (PDF) Alkyl amidopropyl dimethyl amine  68140-01-2 Y Akzo Nobel Surface Chemistry LLC Preliminary results from an oral (gavage) 14-day range-finding study in rats and an OECD 422 reproduction/developmental toxicity screening test in rats.
8EHQ-0411-18302A (PDF) Hexanedioic acid polymer with 1,3-diisocyanatomethylbenzene and 1,2 ethanediol  9019-92-5 N Dow Chemical Company Results of a Local Lymph Node Assay (LLNA) in mice.
8EHQ-0411-18303A (PDF) Ethanol, 2,2'-oxybis-, polymer with 1,3-diisocyanatomethylbenzene and a-hydro-cw-hydroxypoly(oxy-1,4-butanediyl)  65605-50-7 N Dow Chemical Company Results of a Local Lymph Node Assay (LLNA) in mice.
8EHQ-0411-18304A (PDF) Substituted pyrazole *2 CBI   Syngenta Crop Protection, LLC Results from two in vitro genotoxicity assays (reverse mutation assay and mouse lymphoma assay)
8EHQ-0411-18306A (PDF) Mixture containing hydrocarbon solvents, isopropyl alcohol, n-butyl acetate and fluorinated acrylic copolymer *1 CBI   Confidential Preliminary results of an acute inhalation study in rats.
8EHQ-0411-18307A (PDF) 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid  500011-86-9 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a biodegradation study, a micronucleus study and a teratogenicity study in rabbits and rats.
8EHQ-0411-18308A (PDF) Confidential *2 CBI   CBI Results of 3 one-week oral toxicity studies and a one-month oral toxicity study in rats
8EHQ-0411-18309A (PDF) CBI *2 CBI   CBI Results of a micronucleus test
8EHQ-0411-18310A (PDF) Confidential *2 CBI   Confidential Results of an acute oral toxicity test in rats
8EHQ-0411-18311A (PDF) Confidential (formulation) *2 CBI   Confidential Results of an acute toxicity study in water flea (Daphnia magna)
8EHQ-0411-18313A (PDF) Propanediamide, 2,2-dibromo-  73003-80-2 N Dow Chemical Company Results of an acute inhalation study in rats
8EHQ-0411-18314A (PDF) Propane, 1,1,1,3,3,3-hexafluoro- *1 690-39-1 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a biodegradation test
8EHQ-0411-18315A (PDF) 4,4'-Dihydroxy-biphenyl diglycidyl ether  2461-46-3 N Valspar Corporation Results of a bacterial reverse mutation screen and a TL5178Y TK+/- mouse lymphoma forward mutation screen
8EHQ-0411-18316A (PDF) Confidential  CBI   Confidential Findings from an OECD 440 uterotrophic assay in rodents and an OECD 421 reproductive toxicity screening assay in rodents
8EHQ-0411-18317A (PDF) Confidential *2 CBI   Confidential Results of an acute toxicity test on aquatic water plants (Lemna gibba)
8EHQ-0411-18318A (PDF) Substance B *2 CBI   Confidential Results of a toxicity study with green algae (Pseudokirchneriella subcapitata)
Substance A *2 CBI  
8EHQ-0411-18319A (PDF) PRODUCT 1  CBI   Confidential Results of a growth inhibition test on aquatic water plants (Lemna gibba)
PRODUCT 2  CBI  
8EHQ-0411-18320A (PDF) 1,2-Cyclohexane dicarboxylic acid, di(isononyl)ester *1 474919-59-0 N BASF Corporation Results of an acute i.v. toxicity study in rats
8EHQ-0411-18321A (PDF) Nitric Acid *2 7697-37-2   BASF Corporation Results of an acute toxicity study in the water flea (Daphnia magna)
Palladium Dinitrate  10102-05-3  
8EHQ-0411-18322A (PDF) Confidential *2 CBI   Confidential Results of an in vivo micronucleus screening test in mice
8EHQ-0411-18323A (PDF) PRODUCT 2  CBI   Confidential Results of a toxicity study on green algae
PRODUCT 1  CBI  
8EHQ-0411-18324A (PDF) Confidential  CBI   Confidential Results from a 28-day oral toxicity (gavage) study in rats
8EHQ-0411-18325A (PDF) Silane adduct  CBI   Dow Chemical Company Results of a Local Lymph Node Assay (LLNA) in mice
8EHQ-0411-18326A (PDF) Macrocyclic picolinamide  CBI   Dow Chemical Company Findings from an intravenous absorption, metabolism and elimination probe study in rabbits and rats
8EHQ-0411-18327A (PDF) Methyl-2-(2-chloromethylphenyl)-3-methoxy-2-acrylate  117428-51-0   DuPont Haskell Global Centers for Health and Environmental Sciences Findings from a teratogenicity study in rats and rabbits and an acute oral toxicity study in rats
8EHQ-0411-18328A (PDF) 2,4-disubstituted-1-(heteromonocyclic alkyl)-3-(substituted carbomonocycle)-heterobicycle inner salt  CBI   Confidential Results of an oral developmental toxicity study in rats
8EHQ-0411-18329A (PDF) Hydrofluoroolefin  CBI   Confidential Results of an acute inhalation study in rats.
8EHQ-0411-18330A (PDF) 1,5-Naphthylene Diisocyanate (NDI)  3173-72-6 N Bayer MaterialScience LLC Results of a 90-day inhalation study with a 1-month recovery period in rats
8EHQ-0411-18331A (PDF) Aliphatic Polyisocyanate in Organic Solvent  53880-05-0 N Bayer MaterialScience LLC Results of an acute inhalation toxicity study in rats
8EHQ-0411-18332A (PDF) (2,2-MDI)  2536-05-2 N Bayer MaterialScience LLC Results of a Local Lymph Node Assay in Mice (LLNA/IMDS)
8EHQ-0411-18333A (PDF) Phosphoric acid, mixed esters with partially fluorinated alcohol, ammonium salts *1 CBI   Confidential Results of 2 acute fish toxicity studies
8EHQ-0411-18334A (PDF) 2,4,6,8-Tetramethylcyclotetrasiloxane  2370-88-9 N Silicones Environmental, Health and Safety Council (SEHSC) Preliminary findings from a combined repeated-dose toxicity study with a reproductive/ developmental toxicity screening test in rats
8EHQ-0411-18337A (PDF) Toluene Diisocyanate based adduct in Organic Solvent (TDI Trimer)
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(3-isocyanatomethylphenyl) 
26603-40-7 N Bayer MaterialScience LLC Results of a Local Lymph Node Assay in Mice (LLNA/IMDS)
8EHQ-0411-01708B (PDF) ALIPAL CO-436  Multiple   Rhodia Declassification of information previously submitted as CBI
8EHQ-0411-01708C (PDF) ALIPAL CO-436  Multiple   Rhodia Declassification of information previously submitted as CBI
8EHQ-0411-02011B (PDF) PILT NF TBTO Concentrate  Not provided   PPG Industries Declassification of information previously submitted as CBI.
8EHQ-0411-02011C (PDF) PILT NF TBTO Concentrate  Multiple   PPG Industries, Inc. Declassification of the chemical identity associated with submission 8EHQ-0192-02011A (DCN: 88920000657s)
8EHQ-0411-02013B (PDF) PILT®NF READY-TO-USE WITH CYCLOHEXANONE Mixture  Multiple   PPG Industries, Inc. Declassification of chemical identity in 8EHQ-0192-02013A (88920000659s)
8EHQ-0411-12632B (PDF) Cycloryl SJT surfactant blend product  Mulitple   Rhodia Declassification of the test substance.
8EHQ-0411-12632C (PDF) Cycloryl SJT surfactant blend product  Multiple   Rhodia Declassification of the test substance.
8EHQ-0411-13180B (PDF) Vegetable oil emulsified with alkoxylated vegetable oil and sugar derivatives with an alkyl quaternary ammonium, an amphoteric iminoacid salt, neutralizing amounts of sodium and potassium hydroxide and a small amount of a lithium salt  Multiple   DuPont Declassification of the test substance.
Alkyl phosphate alkanolamine salt mixed with nonionic alkyl-ethoxylate and alkylamide-ethoxylate.  Multiple  
Fatty acid ester emulsified with a cationic alkyl quaternary ammnonium and an alkyl ether  Multiple  
8EHQ-0411-16826B (PDF) N-Methylvalerolactam  931-20-4 N BASF Declassification of the test substance.
8EHQ-0411-16995C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-16996C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17027C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17044B (PDF) Benzeneacetonitrile, 2-methyl-alpha-[2-[[(octylsulfonyl)oxy]imino]-3(2H)-thienylidene]- *1 852246-54-9   BASF Corporation Declassification of chemical identity of test substance in 8EHQ-0108-17044A (88080000087s)
8EHQ-0411-17081C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17104F (PDF) cis-1,1,1,4,4,4-hexafluorobutene  692-49-9   DuPont Haskell Global Centers for Health and Environmental Sciences Results of a cardiac sensitization study in dogs
8EHQ-0411-17208D (PDF) Nanocyl NC 7000 *3 7782-42-5   BASF Corporation Declassification of the identity of the chemical substance in 8EHQ-0808-17208A (88080000251s)
8EHQ-0411-17209C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/developmental toxicity study in rats
8EHQ-0411-17229H (PDF) Perfluorooctanoate Anion (PFOA)  335-67-1 N DuPont Haskell Global Centers for Health and Environmental Sciences PFOA serum sampling results for workers at DuPont site Changshu Works, Changshu, China
8EHQ-0411-17297C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17419B (PDF) N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine *3 102-60-3 Y BASF Corporation Declassification of chemical identity for 8EHQ-0209-17419A
8EHQ-0411-17719B (PDF) Polyetherpolyol  29860-47-7 N BASF Corporation Declassification of chemical identity in 8EHQ-1109-17719 (88100000048s)
8EHQ-0411-17866C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17907C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17944B (PDF) 1,3,5-Triazin-2-amine, 4-methoxy-6-methyl- *1 1668-54-8 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute oral toxicity test in rats
8EHQ-0411-17957C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-17958C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats
8EHQ-0411-18166C (PDF) Confidential *2 CBI   Confidential Results of an oral reproductive/ developmental toxicity study in rats


(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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