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Section 8(e) Substantial Risk Notifications and FYI Submissions Received May 2011

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0511-18335A (PDF) 2-propenenitrile *2 107-13-1 Y DuPont Haskell Global Centers for Health and Environmental Sciences Results of a repeated-dose toxicity study in rats
8EHQ-0511-18336A (PDF) 1H-Benimidazol-6-amine, 2-(4-aminophenyl)  7621-86-5 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an Ames Assay
8EHQ-0511-18338A (PDF) Halogenated pyridine derivative  CBI   Dow Chemical Company Findings from a dietary developemental toxicity screen study in rats
8EHQ-0511-18339A (PDF) Halogenated pyridine derivative  CBI   Dow Chemical Company Findings from a dietary developmental toxicity screen study in rats.
8EHQ-0511-18340A (PDF) Sodium hydrogen [N,N-bis[2- [bis(carboxymethyl)amino]ethyl] glycinato(5-)]ferrate(2-) *3 12389-75-2 N AkzoNobel Results of a reproductive/developmental study in rats
8EHQ-0511-18341A (PDF) Fluorinated alkyloxy carboxylate salt  CBI   3M Environmental, Health and Safety Operations Preliminary data from an oral pharmacokinetic study in rats.
8EHQ-0511-18342A (PDF) Substance A *2 CBI   Confidential Results of acute toxicity tests on aquatic water plants (Lemna gibba)
Substance B *2 CBI  
8EHQ-0511-18343A (PDF) Confidential *2 CBI   Confidential Results of a toxicity study on green algae (Pseudokirchneriella subcapitata)
8EHQ-0511-18344A (PDF) Diphenylguanidine hydrochloride  24245-27-0 N Clariant Corporation Results of an acute oral toxicity study in rats, a bacterial reverse mutation test and an in vitro mammalian chromosome aberration test.
8EHQ-0511-18345A (PDF) 4,4'-methylenedianiline (MDA)  101-77-9 Y American Chemistry Council Diisocyanates Panel Draft report of an acute toxicity (immobilization) study in the water flea (OECD 202)
8EHQ-0511-18346A (PDF) Rosin oil *2 8002-16-2 N Arizona Chemical Company, LLC Results from an acute toxicity study in fish (Brachydanio rerio)
8EHQ-0511-18347A (PDF) Formulation containing two active ingredients (1) [  ] and (2) [  ] *2 CBI   Confidential Results of an acute inhalation study in rats
8EHQ-0511-18348A (PDF) Substance B *2 CBI   Confidential Results of a toxicity study on green algae (Pseudokirchneriella subcapitata)
Substance A *2 CBI  
8EHQ-0511-18349A (PDF) Confidential *2 CBI   Confidential Results of a toxicity study on green algae (Pseudokirchneriella subcapitata)
8EHQ-0511-18350A (PDF) Irgacure 369  119313-12-1 N BASF Corporation Results of a one-generation oral reproduction toxicity study in rats
8EHQ-0511-18351A (PDF) Aerotech 2599  Not provided   Kemira Chemical Report on an acute aquatic toxicity study in invertebrates and fish
8EHQ-0511-18352A (PDF) N,N'-Di-tert-butylacetamidine  54838-72-1 N Dow Chemical Company Results of a modified acute vapor inhalation study in rats
8EHQ-0511-18353A (PDF) Ethyl Violet Liquid Crude  CBI   Confidential Results of a Local Lymph Node Assay (LLNA) in mice.
8EHQ-0511-18354A (PDF) Alkyl 2-[5-(dihydro-3-alkyl-disubstituted-4-substituted-1-heteromonocyclic]- dihalo-carbomonocyclicoxy) carbomonocyclicoxy]2-alkoxyacetate  Not provided   Confidential Results of a 14-day repeated dose toxicity study in rats
8EHQ-0511-18355A (PDF) Hydrofluorocarbon Fluid  CBI   Confidential Results of an acute inhalation study in rats
8EHQ-0511-18357A (PDF) Buckman 157  Not provided   Buckman Laboratories, Inc. Adverse effects incident report involving an alleged exposure to a product distributed by Buckman Laboratories.
8EHQ-0511-18358A (PDF) Rosin, maleated, polymer with pentaerythritol *3 68333-69-7 N Arizona Chemical Company, LLC Reports summarizing 2 local lymph node assays in mice and a guinea pig maximization skin sensitization test.
8EHQ-0511-01302B (PDF) Benzoic acid, 2-[[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-
triazin-2-yl]aminocarbonyl]aminosulfonyl]-3-methyl-,methyl ester *2
126535-15-7 N DuPont Legal Declassification of the test substance.
8EHQ-0511-01358B (PDF) Benzoic acid, 2-[[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-
triazin-2-yl]aminocarbonyl] aminosulfonyl]-3-methyl-,methyl ester *2
126535-15-7 N DuPont Legal Declassification of chemical identity previously claimed as CBI in 8EHQ-1091-01358 (88920000003)
8EHQ-0511-02354C (PDF) Amocool HD Soluble Oil  Not provided   Chevron Corporation Declassification of chemical identity in TSCA Submission 8EHQ-0292-2354
8EHQ-0511-04171B (PDF) Acetate Fiber Finish (mixture)  Not provided   Celanese Corporation Declassification of 8EHQ-0592-4171
8EHQ-0511-12853B (PDF) Not provided  Not provided   BP Correspondence regarding declassification of TSCA (8e) submission of August 25, 1992
8EHQ-0511-12901B (PDF) Not Provided  Not Provided   Huntsman International LLC Correspondence regarding declassification of 8EHQ-94-12901
8EHQ-0511-13020B (PDF) Multiple  Multiple   The Procter & Gamble Company Declassified chemical identity for 8EHQ-94-13020 (EPA DCN 88940000262)
8EHQ-0511-13737P (PDF) Indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl]amino]carbonyl]-,methyI ester, (S)-, active isomer *2 173584-44-6 N DuPont Legal Declassification of chemical identity previously claimed as CBI in submission 8EHQ-0996-13737 (EPA DCN 88960000217).
Indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl]amino]carbonyl]-,methyl ester, (R)-, inactive isomer *2 None  
8EHQ-0511-13750B (PDF) Indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl]amino]carbonyl]-,methyl ester, (S)-, Active isomer *2 173584-44-6 N DuPont Legal Declassification of the test substance in 8EHQ-0996-13750 (88960000230)
lndeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbony)[4- (trifluoromethoxy) phenyl]amino]carbonyl]-,methyl ester, (R)- Inactive isomer  None  
8EHQ-0511-13833B (PDF) Indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl]amino]carbonyl]-,methyl ester, (S)-, Active isomer *2 173584-44-6 N DuPont Legal Declassification of the test substance in submission 8EHQ-0996-13833 (88970000083)
Indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy) phenyl]amino]carbonyl]-,methyl ester, (R)-, Inactive isomer  None  
8EHQ-0511-13884B (PDF) 2-Thiophenecarboxylic acid, 3-amino-, methyl ester *1 22288-78-4 N DuPont Legal Declassification of the test substance in 8EHQ-0297-13884 (88970000134).
8EHQ-0511-13926B (PDF) Indeno[1,2-e][1,3 ,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)-[4-(trifluoromethoxy)phenyl]amino] carbonyl]-, methyl ester, (R)-  Not Provided   DuPont Legal Declassification of the test substance in 8EHQ-0597-13926 (88970000176)
8EHQ-0511-15217B (PDF) 70% mixture of 2, 4-Oxazolidinedione, 5-methyl-5- (4-phenoxyphenyl)-3-(phenylamino), copper hydroxide and 30% EPA approved inerts *2 131807-57-3 & 20427-59-2 N DuPont Legal Declassification of the test substance in 8EHQ-1002-15217 (88030000012)
8EHQ-0511-15945AF (PDF) 3-Bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide *2 736994-63-1 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a 2-year feeding study in rats with 3-Bromo- 1 -(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide (CAS No. 736994-63-1)
8EHQ-0511-16929D (PDF) Ethylene (or Ethene)  74-85-1 Y American Chemistry Council Results of a 4-week Inhalation Study in rats
8EHQ-0511-17004B (PDF) 9-Octadecenoic acid (Z)-, reaction products with 2-[(2-aminoethyl)amino]ethanol  68815-51-0 N BASF Corporation Declassification of the chemical identity in 8EHQ-1107-17004 (88080000047)
8EHQ-0511-17229I (PDF) PFOA  335-67-1   DuPont Haskell Global Centers for Health and Environmental Sciences Results of an occupational PFOA serum sampling for workers
8EHQ-0511-17229J (PDF) PFOA  335-67-1   DuPont Haskell Global Centers for Health and Environmental Sciences Results of an occupational PFOA serum sampling study for workers
8EHQ-0511-17229K (PDF) PFOA  335-67-1   DuPont Haskell Global Centers for Health and Environmental Sciences Results of an occupational serum sampling study in workers with PFOA
8EHQ-0511-17229L (PDF) PFOA  335-67-1   DuPont Haskell Global Centers for Heath and Environmental Sciences Results of an occupational serum sampling study for workers with PFOA
8EHQ-0511-17229M (PDF) PFOA  335-67-1   DuPont Haskell Global Centers for Health and Environmental Sciences Results from an occupational PFOA serum sampling for workers
8EHQ-0511-17604B (PDF) Poly(oxy-1,2-ethanediyl), alpha-[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropyl]-omega-[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropoxy] *1 36541-61-4 N BASF Declassification of the test substance.
8EHQ-0511-17645B (PDF) Polymin P  68130-97-2 N BASF Declassification of the test substance.
8EHQ-0511-17792B (PDF) Colloidal Calcium-Silicate Preparation *3 1344-95-2 N BASF Declassification of the test substance.
8EHQ-0511-18272B (PDF) MTDID 25671  CBI   3M Preliminary data for an inhalation toxicity study conducted in Sprague Dawley rats on hydrofluoroketone
8EHQ-0511-18273B (PDF) MTDID 24621  CBI   3M Results of an acute inhalation study in rats
8EHQ-0511-18305B (PDF) MTDID 24910  CBI   3M Results of an inhalation toxicity study in rats
FYI-0511-01680A (PDF)          


(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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