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Section 8(e) Substantial Risk Notifications and FYI Submissions Received March 2013

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8EHQ/FYI#
Chemical Name
CASRN
Submitter
Submission Description
8EHQ-0313-19011A (PDF) Methyl ester, soybean oil 67784-80-9 DuPont Haskell Global Centers for Health and Environmental Sciences The Results of a Local Lymph Node Assay (LLNA) with Methyl ester, soybean oil (CASRN 67784-80-9)
8EHQ-0313-19012A (PDF) Methyl canolate 67762-38-3 DuPont Haskell Global Centers for Health and Environmental Sciences The Results of a Local Lymph Node Assay (LLNA) with Methyl Canolate (CASRN 67762-38-3)
8EHQ-0313-19013A (PDF) Siloxanes and Silicones, di-methyl 3-hydroxypropyl methyl ethoxylated propoxylated 68937-55-3 DuPont Haskell Global Centers for Health and Environmental Sciences The Results of a Local Lymph Node Assay (LLNA) with Siloxanes and Silicones, Di-methyl 3-hydroxypropyl methyl ethoxylated propoxylated (CASRN 68937-55-3)
8EHQ-0313-19014A (PDF) Confidential Confidential Dow Chemical Company The Results of an Acute Inhalation Toxicological Study with Lithiated Metal Phosphate (Generic name).
8EHQ-0313-19015A (PDF) Confidential *2 Confidential Syngenta Crop protection, LLC The Results of a Repeat Dose Toxicity Studies in Rats with Substituted Benzamide (Generic Name)
8EHQ-0313-19016A (PDF) Pentamethyl diethylenetriamine (PMDETA) 3030-47-5 Huntsman Corporation Preliminary Results from a Combined Repeated Dose Toxicity Study with the Reproductive/ Development Toxicity Screening Testing in Rats with PMDETA (Pentamethyl diethylenetriamine,   CASRN 3030-47-5)
8EHQ-0313-19017A (PDF) 3,9-Di-3-cyclohexene-1-yl-2,4,8,10-tetraoxaspiro[5.5]undecane (Vulkazon AFS) Not Provided LanXess Corporation The Results of a 21-day Daphnia magna Reporduction Study with Vulkazon AFS (3,9-Di-3-cyclohexene-1-yl-2,4,8,10-tetraoxaspiro[5.5]undecane, CASRN Not Provided)
8EHQ-0313-19019A (PDF) Phenol, 4,4'-(1 -methylethylidene)bis-, polymer with 5-amino-I,3,3-trimethylcyclohexanemethanamine and 2-(chloromethyl)oxirane 38294-64-3 Dow Chemical Company Report on a Repeated Dose Study in Rats with Phenol, 4,4'-(1 -methylethylidene)bis-, polymer with 5-amino-I,3,3-trimethylcyclohexanemethanamine and 2-(chloromethyl)oxirane (CASRN 38294-64-3)
8EHQ-0313-19020A (PDF) Aminopropyl Vinyl Ether 66415-55-2 BASF Results of a Skin Sensitization Study (LLNA) with Aminopropyl Vinyl Ether, CASRN 66415-55-2
8EHQ-0313-19021A (PDF) Confidential *2 Not Provided Confidential The Results of a Bioconcentration Study in Rainbow trout (Oncorhynchus mykiss)
8EHQ-0313-19022A (PDF) Confidential *2 Not Provided Confidential The Results of an Acute Toxicity Study in Water Flea (Daphnia magna) with a Pesticide Formulation.
8EHQ-0313-19023A (PDF) Neononyl Acetate (3,5,5-trim ethyl hexyl acetate) 58430-94-7 Symrise, Inc Results of a Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (OECD422) for Neononyl Acetate (3,5,5-trim ethyl hexyl acetate) (CASRN 58430-94-7)
8EHQ-0313-19024A (PDF) Confidential *2 Confidential Confidential Results of a Test Study in Female, Non-Pregnant Wistar Rats with a Developmental Pesticide
8EHQ-0313-19025A (PDF) Sulfonium compounds,C11-14-alkylbis(hydroxyethyl),2- hydroxyethyl sulfates (salts) 78169-20-7 BASF Results of a toxicity test in Algae, Pseudokirchneriella subcapitata, with Sulfonium compounds,C11-14-alkylbis(hydroxyethyl),2- hydroxyethyl sulfates (salts), (CASRN 78169-20-7)
8EHQ-0313-19026A (PDF) Ethylene Urea 120-93-4 BASF The Results of an OECD 407 Repeated Dose 28-day Oral Toxicity Study in Wistar rats [Crl:WI(HAN)] with Ethylene Urea, CASRN 120-93-4
8EHQ-0313-19027A (PDF) 1,2-Ethylenediamine *3 107-15-3 Dow Chemical Company The Results of an Acute Inhalation Study with Fisher 344 Rats after exposure to 1,2-Ethylenediamine (CASRN 107-15-3)
8EHQ-0313-19028A (PDF) 2-Methyl-2-propenoic acid 2-hydroxyethyl ester phosphate 52628-03-2 Dow Chemical Company The Results of a Repeated Dose Study with Fisher 344 Rats after exposure to 2-Methyl-2-propenoic acid 2-hydroxyethyl ester phosphate (CASRN 52628-03-2)
8EHQ-0313-19029A (PDF) tert. butylperoxy-3,5,5-trimethylhexanoate 13122-18-4 United Initiators, Inc. The Results for a Prenatal Developmental Toxicity Study with tert. butylperoxy-3,5,5-trimethylhexanoate (TBPIN, CASRN 13122-18-4) in the Rat.
8EHQ-0313-19030A (PDF) Ter-butyl cumyl peroxide 3457-61-2 Arkema, Inc. The Results of a Combined Repeated Dose Toxicity Study with the Reproductions/developmental Toxicity Screening  Test in Rats after Exposure to ter-butyl cumyl peroxide (CASRN Number 3457-61-2)
8EHQ-0313-19031A (PDF) -Propenoic acid, 2-[[[[3-(methylthio)phenyl]amino]carbonyl]oxy] ethyl ester  1207339-61-4 Bayer Material Science LLC The Results of a Local Lymph Node Assay in Mice (LLNA/ IMDS) with 2-Propenoic acid, 2-[[[[3-(methylthio) phenyl] amino]carbonyl]oxy] ethyl ester (CASRN 1207339-61-4)
8EHQ-0313-19032A (PDF) Confidential Confidential Confidential The Results of an Ames assay with Polyaromatic amine (Generic name).
8EHQ-0313-19033A (PDF) Confidential Confidential Confidential The Results of an Ames assay with Substituted carbopolycycle (Generic name).
8EHQ-0313-19034A (PDF) Confidential *2 Confidential Confidential The Results of an Acute Daphnia magna toxicity Study with a R&D Formulation containing a Partially Fluorinated Acrylic Copolymer in Water-cosolvent (Generic name).
8EHQ-0313-19035A (PDF) Confidential Confidential Syngenta Crop Protection, LLC Reproduction and Investigative Littering Studies in Rats with a Substituted Benzamide
8EHQ-0313-19036A (PDF) Confidential Confidential Syngenta Crop Protection, LLC Preliminary Oral (Gavage) Prenatal Developmental Toxicity Study in the Rabbit with a Substituted Pyranone
8EHQ-0313-19037A (PDF) Confidential Confidential Dow Chemical Company The Results of a Developmental Toxicity Study with Rabbits after a 7 to 28-day Exposure to Macrocyclic picolinamide (Generic Name).
8EHQ-0313-19038A (PDF) Confidential *2 Confidential Confidential Results of an Acute Toxicity Study on Honey bee (Apis meiifera)
8EHQ-0313-19039A (PDF) Confidential *2 Confidential Confidential Results of a Prenatal Developmental Toxicity Study in Wistar Rats
8EHQ-0313-19040A (PDF) Confidential *2 Confidential Confidential Results of an Toxicity Study (Green Alga Pseudokirchneriella subcapitata) with Two Experimental Pesticides
8EHQ-0313-19041A (PDF) Bis(2-propylheptyl) Phthalate 53306-54-0 BASF The Results of a Five Day Inhalation Study in male Wistar rats with Bis(2-propylheptyl) Phthalate (CASRN 53306-54-0) as a Liquid Aerosol
8EHQ-0313-19042A (PDF) 1,4-Butanediylbis(oxy (2-hydroxy-3,1-propanediyl))diacrylate 52408-42-1 BASF The Results of OECD 422 Combined Repeated Dose Toxicity Study with the Reproduction/ Developmental Toxicity Screening Test in Wistar Rats with 1,4-Butanediylbis(oxy (2-hydroxy-3,1-propanediyl))diacrylate, (CASRN 52408-42-1)
8EHQ-0313-19043A (PDF) 4,4'-Diamino-3,3',5,5'-tetramethyl-dicyclohexylmethane 65962-45-0 BASF The Results of a Test Study in Wistar Rats with Administration by gavage for 14 days with 4,4'-Diamino-3,3',5,5'-tetramethyl-dicyclohexylmethane (CASRN 65962-45-0)
8EHQ-0313-19044A (PDF) Confidential Confidential Confidential The Results of two Endocrine assays with N-(trisubstituted carbomonocycle)- (disubstituted carbomonocycle)-dialkyl-heteromonocyclic amine (Generic Name)
8EHQ-0313-19045A (PDF) Di-(4-tert-butylcyclohexyl)-peroxydicarbonate 15520-11-3 Pergan Marchall, LLC The Results of an Acute Immobilization in Daphnia magna and an Algae Growth Inhibition Test with Di-(4-tert-butylcyclohexyl)-peroxydicarbonate (CASRN 15520-11-3)
8EHQ-0313-19046A (PDF) Bis(3,5,5-trimethylhexanoyl)peroxide and Isododecane 3851-87-4 & 93685-81-5 Pergan Marchall, LLC The Results of an Acute Immobilization in an Algae Growth Inhibition Test and an Acute Fish Toxicity test with Bis(3,5,5-trimethylhexanoyl)peroxide (CASRN 3851-87-4) 75% in isododecane (CASRN 93685-81-5), as Stabiliser
8EHQ-0313-19047A (PDF) Tert-amyl hydroperoxide 3425-61-4 Arkema, Inc. The Results on a 72-hour Algal Growth Inhibition Study using Tert-amyl hydroperoxide (CASRN 3425-61-4)
8EHQ-0313-19048A (PDF) OO-t-butyl-O-(2-ethylhexyl)monoperoxycarbonate 34443-12-4 Arkema, Inc. The Results on a 72-hour Algal Growth Inhibition Study using OO-t-butyl-O-(2-ethylhexyl) monoperoxycarbonate (CASRN 34443-12-4)
8EHQ-0313-19049A (PDF) Tert-amyl peroxy-2-ethyl hexanoate 686-31 -7 Arkema, Inc. The Results on a 72-hour Algal Growth Inhibition Study using tert-amyl peroxy-2-ethyl hexa no ate (CASRN 686-31 -7)
8EHQ-0313-19050A (PDF) Tert-butyl cumyl peroxide 3457-61-2 Arkema, Inc. The Results on a 48-hour Daphnia magna Acute Immobilisation Test using tert-butyl cumyl peroxide (CASRN 3457-61-2)
8EHQ-0313-19051 (PDF) 2-[(1-methylpropyl)amino]ethanol 35265-04-4 Arkema, Inc. The Results of a Range Finding and Main Inhalation Studies in Rats indicate that Repeated Exposure to 2-[(1-methylpropyl)amino]ethanol (CASRN 35265-04-4)
8EHQ-0313-19052A (PDF) 2-Propenoic acid, 2-[[[[3-(methylthio) phenyl]amino]carbony]oxy]ethylester 1207339-61-4 Bayer Material Science LLC Summaries on an Alga Growth Inhibition Test, an Inherent Biodegradability Test, and a Biodegradation test with RLS 3187 (2-Propenoic acid, 2-[[[[3-(methylthio) phenyl]amino] carbony]oxy]ethylester (CASRN 1207339-61-4)
8EHQ-0313-19054A (PDF) N, N-Dimethyl Tall Oil Fatty Amides (DMATO) 68308-74-7 Buckman Laboratories, Inc. The Results of a Local Lymph Node Assay in the Mouse with N, N-Dimethyl Tall Oil Fatty Amides (DMATO) CASRN: 68308-74-7
8EHQ-0313-19055A (PDF) Furan 110-00-9 Lyondell Chemical Company The Reporting of a Preliminary Estimate of Furan (CASRN 110-00-9) for a Screening Risk Assessment in Humans
8EHQ-0313-18164C (PDF) Confidential *2 Confidential Monsanto Company Notification of the Final Results of a Reproductive Toxicity Study with Rabbits
8EHQ-0313-18664D (PDF) Confidential Not Provided Confidential The Results of a Subchronic Oral Toxicity Study with Dioxopyrimidium inner salt (Generic Name) (CASRN Not Provided).
8EHQ-0313-18664E (PDF) Confidential Confidential Confidential The Results of an Acute Oral and a Repeated Dose Toxicity Studies with Dioxopyrimidium, Inner Salt (Generic Name)
FYI-0313-01708B (PDF) PFOS Not Provided Taft Stettinius & Hollister LLP A For Your Information Report Referencing a February 28, 2013 Submission from DuPont.
8EHQ-0313-19238 (PDF)        

*1 =  PMN;  *2  =  Pesticide;  * 3 = Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission.  8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s.  The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A).  The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
 
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters.  Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number.  Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information.  This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

Description - A general description of the type of study or information submitted, but not study results.  A PDF electronic copy of the submission is attached.


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