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Methyl tert-Butyl Ether (MTBE) Test Results


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CAS No. 1634-04-4

ITC Recommendation/Designation - 19th and 20th Reports
51 FR 41417;November 14, 1986
52 FR 19020; May 20, 1987

Consent Agreement (CO)
53 FR 10391; March 31, 1988
Methyl tertiary Butyl Ether Committee (MTBE Health Effects Testing Task Force)

Modifications
54 FR 27352; June 29, 1989/Technical Amendment

Project Manager: R. Locke

Section Chief: R. Northrop

Status: Closed. All required tests have been completed. Test results have been forwarded to the Risk Assessment Division for review and disposition.

Announced Receipt of Test Data

Sex-linked recessive lethal test (Drosophila melanogaster) (54 FR 21282; May 17, 1989).

In vivo inhalation cytogenetics study (rats) (54 FR 25167; June 13, 1989).

Inhalation developmental toxicity study (rabbits) (54 FR 32117; August 4, 1989).

Inhalation developmental toxicity study (mice) (54 FR 21117; August 16, 1989).

Test data was received from the Synthetic Organic Chemical Manufacturers Association for a single exposure and repeated exposure vapor inhalation toxicity study with neurotoxicity evaluation (rats) (54 FR 42034; October 13, 1989).

The MTBE Health Effects Testing Task Force submitted pharmacokinetics test results (male and female rats) by oral, dermal, and inhalation routes of exposure (55 FR 29411; July 19, 1990).

MTBE submitted vapor inhalation oncogenicity studies on CD-1 mice and Fischer 344 rats (57 FR 59111; December 14, 1992).

Results of Testing Table



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