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Significant New Uses of Certain Chemical Substances

[Federal Register: March 28, 2003 (Volume 68, Number 60)]
[Rules and Regulations]               
[Page 15061-15089]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr28mr03-9]                         

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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Part 721

[OPPT-2002-0060; FRL-6758-7]
RIN 2070-AB27

 
Significant New Uses of Certain Chemical Substances

AGENCY: Environmental Protection Agency (EPA).

[[Page 15062]]


ACTION: Direct final rule.

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SUMMARY: EPA is promulgating significant new use rules (SNURs) under 
section 5(a)(2) of the Toxic Substances Control Act (TSCA) for 62 
chemical substances which were the subject of premanufacture notices 
(PMNs) and subject to TSCA section 5(e) consent orders issued by EPA. 
Today's action requires persons who intend to manufacture, import, or 
process these substances for a significant new use to notify EPA at 
least 90 days before commencing the manufacturing or processing of the 
substance for a use designated by this rule as a significant new use. 
The required notice will provide EPA with the opportunity to evaluate 
the intended use, and if necessary, to prohibit or limit that activity 
before it occurs to prevent any unreasonable risk of injury to human 
health or the environment. EPA is promulgating this SNUR using direct 
final procedures.

DATES: The effective date of this rule is May 27, 2003 without further 
notice, unless EPA receives adverse comment or notice of intent to 
submit adverse comment before April 28, 2003. This rule shall be 
promulgated for purposes of judicial review at 1 p.m. (e.s.t.) on April 
11, 2003.
    If EPA receives adverse comment or notice before April 28, 2003 
that someone wishes to submit adverse or critical comments on EPA's 
action in establishing a SNUR for one or more of the chemical 
substances subject to this rule, EPA will withdraw the SNUR before the 
effective date for the substance for which the comment or notice of 
intent to comment is received and will issue a proposed SNUR providing 
a 30-day period for public comment.

ADDRESSES: Comments or notice of intent to submit adverse or critical 
comments may be submitted electronically, by mail, or through hand 
delivery/courier. Follow the detailed instructions as provided in Unit 
I. of the SUPPLEMENTARY INFORMATION.

FOR FURTHER INFORMATION CONTACT: For general information contact: 
Barbara Cunningham, Acting Director, Environmental Assistance Division 
(7408M), Office of Pollution Prevention and Toxics, Environmental 
Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-
0001; telephone number: (202) 554-1404; e-mail address: TSCA-
Hotline@epa.gov.    For technical information contact: James Alwood, Chemical Control 
Division (7405M), Office of Pollution Prevention and Toxics, 
Environmental Protection Agency, 1200 Pennsylvania Ave., NW., 
Washington, DC 20460-0001; telephone number: (202) 564-8974; e-mail 
address: alwood.jim@epa.gov.
SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this Action Apply to Me?

    You may be potentially affected by this action if you manufacture, 
import, process, or use the chemical substances contained in this rule. 
Potentially affected entities may include, but are not limited to:
    [sbull] Chemical manufacturers (NAICS 325), e.g., Manufacturers, 
importers, processors, and users of chemicals.
    [sbull] Petroleum and coal product industries (NAICS 324), e.g., 
Manufacturers, importers, processors, and users of chemicals.
    This listing is not intended to be exhaustive, but rather provides 
a guide for readers regarding entities likely to be affected by this 
action. Other types of entities not listed in this unit could also be 
affected. The North American Industrial Classification System (NAICS) 
codes have been provided to assist you and others in determining 
whether this action might apply to certain entities. To determine 
whether you or your business may be affected by this action, you should 
carefully examine the applicability provisions in title 40 of the Code 
of Federal Regulations (CFR) at 40 CFR 721.5. If you have any questions 
regarding the applicability of this action to a particular entity, 
consult the technical person listed under FOR FURTHER INFORMATION 
CONTACT.

B. How Can I Get Copies of This Document and Other Related Information?

    1. Docket. EPA has established an official public docket for this 
action under docket identification (ID) number OPPT-2002-0060 . The 
official public docket consists of the documents specifically 
referenced in this action, any public comments received, and other 
information related to this action. Although a part of the official 
docket, the public docket does not include Confidential Business 
Information (CBI) or other information whose disclosure is restricted 
by statute. The official public docket is the collection of materials 
that is available for public viewing at the EPA Docket Center, Rm. 
B102-Reading Room, EPA West, 1301 Constitution Ave., NW., Washington, 
DC. The EPA Docket Center is open from 8:30 a.m. to 4:30 p.m., Monday 
through Friday, excluding legal holidays. The EPA Docket Center Reading 
Room telephone number is (202) 566-1744 and the telephone number for 
the OPPT Docket, which is located in EPA Docket Center, is (202) 566-
0280.
    2. Electronic access. You may access this Federal Register document 
electronically through the EPA Internet under the "Federal Register" 
listings at http://www.gpo.gov/fdsys/search/home.action. The OPPTS harmonized test 
guidelines referenced in this document are available at http://www.epa.gov/opptsfrs/home/guidelin.htm.
 A frequently updated electronic 
version of 40 CFR part 721 is available at http://www.access.gpo.gov/nara/cfr/cfrhtml_00/Title_40/40cfr
 721--00.html, a beta site 
currently under development.
    An electronic version of the public docket is available through 
EPA's electronic public docket and comment system, EPA Dockets. You may 
use EPA Dockets at http://www.epa.gov/edocket/ to submit or view public 
comments, access the index listing of the contents of the official 
public docket, and to access those documents in the public docket that 
are available electronically. Although not all docket materials may be 
available electronically, you may still access any of the publicly 
available docket materials through the docket facility identified in 
Unit I.B.1. Once in the system, select "search," then key in the 
appropriate docket ID number.
    Certain types of information will not be placed in the EPA Dockets. 
Information claimed as CBI and other information whose disclosure is 
restricted by statute, which is not included in the official public 
docket, will not be available for public viewing in EPA's electronic 
public docket. EPA's policy is that copyrighted material will not be 
placed in EPA's electronic public docket but will be available only in 
printed, paper form in the official public docket. To the extent 
feasible, publicly available docket materials will be made available in 
EPA's electronic public docket. When a document is selected from the 
index list in EPA Dockets, the system will identify whether the 
document is available for viewing in EPA's electronic public docket. 
Although not all docket materials may be available electronically, you 
may still access any of the publicly available docket materials through 
the docket facility identified in Unit I.B.1. EPA intends to work 
towards providing electronic access to all of the publicly available 
docket materials through EPA's electronic public docket.
    For public commenters, it is important to note that EPA's policy is 
that public comments, whether submitted electronically or in paper,

[[Page 15063]]

will be made available for public viewing in EPA's electronic public 
docket as EPA receives them and without change, unless the comment 
contains copyrighted material, CBI, or other information whose 
disclosure is restricted by statute. When EPA identifies a comment 
containing copyrighted material, EPA will provide a reference to that 
material in the version of the comment that is placed in EPA's 
electronic public docket. The entire printed comment, including the 
copyrighted material, will be available in the public docket.
    Public comments submitted on computer disks that are mailed or 
delivered to the docket will be transferred to EPA's electronic public 
docket. Public comments that are mailed or delivered to the docket will 
be scanned and placed in EPA's electronic public docket. Where 
practical, physical objects will be photographed, and the photograph 
will be placed in EPA's electronic public docket along with a brief 
description written by the docket staff.

C. How and To Whom Do I Submit Comments?

    You may submit comments electronically, by mail, or through hand 
delivery/courier. To ensure proper receipt by EPA, identify the 
appropriate docket ID number in the subject line on the first page of 
your comment. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the close of the 
comment period will be marked "late." EPA is not required to consider 
these late comments. If you wish to submit CBI or information that is 
otherwise protected by statute, please follow the instructions in Unit 
I.D. Do not use EPA Dockets or e-mail to submit CBI or information 
protected by statute.
    1. Electronically. If you submit an electronic comment as 
prescribed in this unit, EPA recommends that you include your name, 
mailing address, and an e-mail address or other contact information in 
the body of your comment. Also include this contact information on the 
outside of any disk or CD ROM you submit, and in any cover letter 
accompanying the disk or CD ROM. This ensures that you can be 
identified as the submitter of the comment and allows EPA to contact 
you in case EPA cannot read your comment due to technical difficulties 
or needs further information on the substance of your comment. EPA's 
policy is that EPA will not edit your comment, and any identifying or 
contact information provided in the body of a comment will be included 
as part of the comment that is placed in the official public docket, 
and made available in EPA's electronic public docket. If EPA cannot 
read your comment due to technical difficulties and cannot contact you 
for clarification, EPA may not be able to consider your comment.
    i. EPA Dockets. Your use of EPA's electronic public docket to 
submit comments to EPA electronically is EPA's preferred method for 
receiving comments. Go directly to EPA Dockets at http://www.epa.gov/edocket/
, and follow the online instructions for submitting comments. 
Once in the system, select "search," and then key in docket ID number 
OPPT-2002-0060. The system is an "anonymous access" system, which 
means EPA will not know your identity, e-mail address, or other contact 
information unless you provide it in the body of your comment.
    ii. E-mail. Comments may be sent by e-mail to oppt.ncic@epa.gov, 
Attention: Docket ID Number OPPT-2002-0060. In contrast to EPA's 
electronic public docket, EPA's e-mail system is not an "anonymous 
access" system. If you send an e-mail comment directly to the docket 
without going through EPA's electronic public docket, EPA's e-mail 
system automatically captures your e-mail address. E-mail addresses 
that are automatically captured by EPA's e-mail system are included as 
part of the comment that is placed in the official public docket, and 
made available in EPA's electronic public docket.
    iii. Disk or CD ROM. You may submit comments on a disk or CD ROM 
that you mail to the mailing address identified in Unit I.C.2. These 
electronic submissions will be accepted in WordPerfect or ASCII file 
format. Avoid the use of special characters and any form of encryption.
    2. By mail. Send your comments to: Document Control Office (7407M), 
Office of Pollution Prevention and Toxics (OPPT), Environmental 
Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-
0001.
    3. By hand delivery or courier. Deliver your comments to: OPPT 
Document Control Office (DCO) in EPA East Building Rm. 6428, 1201 
Constitution Ave., NW., Washington, DC. Attention: Docket ID Number 
OPPT-2002-0060. The DCO is open from 8 a.m. to 4 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the DCO is 
(202) 564-8930.

D. How Should I Submit CBI To the Agency?

    Do not submit information that you consider to be CBI 
electronically through EPA's electronic public docket or by e-mail. You 
may claim information that you submit to EPA as CBI by marking any part 
or all of that information as CBI (if you submit CBI on disk or CD ROM, 
mark the outside of the disk or CD ROM as CBI and then identify 
electronically within the disk or CD ROM the specific information that 
is CBI). Information so marked will not be disclosed except in 
accordance with procedures set forth in 40 CFR part 2.
    In addition to one complete version of the comment that includes 
any information claimed as CBI, a copy of the comment that does not 
contain the information claimed as CBI must be submitted for inclusion 
in the public docket and EPA's electronic public docket. If you submit 
the copy that does not contain CBI on disk or CD ROM, mark the outside 
of the disk or CD ROM clearly that it does not contain CBI. Information 
not marked as CBI will be included in the public docket and EPA's 
electronic public docket without prior notice. If you have any 
questions about CBI or the procedures for claiming CBI, please consult 
the technical person listed under FOR FURTHER INFORMATION CONTACT.

E. What Should I Consider as I Prepare My Comments for EPA?

    We invite you to provide your views on the various options we 
propose, new approaches we haven't considered, the potential impacts of 
the various options (including possible unintended consequences), and 
any data or information that you would like the Agency to consider 
during the development of the final action. You may find the following 
suggestions helpful for preparing your comments:
    1. Explain your views as clearly as possible.
    2. Describe any assumptions that you used.
    3. Provide copies of any technical information and/or data you used 
that support your views.
    4. If you estimate potential burden or costs, explain how you 
arrived at the estimate that you provide.
    5. Provide specific examples to illustrate your concerns.
    6. Offer alternative ways to improve the rule.
    7. Make sure to submit your comments by the deadline in this 
document.
    8. To ensure proper receipt by EPA, be sure to identify the docket 
ID number assigned to this action in the subject line on the first page 
of your response. You may also provide the name, date, and Federal 
Register citation.

[[Page 15064]]

II. Background

A. What Action is the Agency Taking?

    This SNUR will require persons to notify EPA at least 90 days 
before commencing manufacturing, importing, or processing a substance 
for any activity designated by this SNUR as a significant new use. The 
supporting rationale and background to this rule are more fully set out 
in the preamble to EPA's first direct final SNUR published in the 
Federal Register of April 24, 1990 (55 FR 17376). Consult that preamble 
for further information on the objectives, rationale, and procedures 
for the rules and on the basis for significant new use designations 
including provisions for developing test data.

B. What is the Agency's Authority for Taking this Action?

    Section 5(a)(2) of TSCA (15 U.S.C. 2604(a)(2)) authorizes EPA to 
determine that a use of a chemical substance is a "significant new 
use." EPA must make this determination by rule after considering all 
relevant factors, including those listed in section 5(a)(2) of TSCA. 
Once EPA determines that a use of a chemical substance is a significant 
new use, section 5(a)(1)(B) of TSCA requires persons to submit a notice 
to EPA at least 90 days before they manufacture, import, or process the 
substance for that use. The mechanism for reporting under this 
requirement is established under 40 CFR 721.5.

C. Applicability of General Provisions

    General provisions for SNURs appear under subpart A of 40 CFR part 
721. These provisions describe persons subject to the rule, 
recordkeeping requirements, exemptions to reporting requirements, and 
applicability of the rule to uses occurring before the effective date 
of the final rule. Provisions relating to user fees appear at 40 CFR 
part 700. Persons subject to this SNUR must comply with the same notice 
requirements and EPA regulatory procedures as submitters of PMNs under 
section 5(a)(1)(A) of TSCA. In particular, these requirements include 
the information submission requirements of TSCA section 5(b) and 
5(d)(1), the exemptions authorized by TSCA section 5 (h)(1), (h)(2), 
(h)(3), and (h)(5), and the regulations at 40 CFR part 720. Once EPA 
receives a SNUR notice, EPA may take regulatory action under TSCA 
section 5(e), 5(f), 6, or 7 to control the activities on which it has 
received the SNUR notice. If EPA does not take action, EPA is required 
under TSCA section 5(g) to explain in the Federal Register its reasons 
for not taking action.
    Persons who intend to export a substance identified in a proposed 
or final SNUR are subject to the export notification provisions of TSCA 
section 12(b). The regulations that interpret TSCA section 12(b) appear 
at 40 CFR part 707. Persons who intend to import a chemical substance 
identified in a final SNUR are subject to the TSCA section 13 import 
certification requirements, which are codified at 19 CFR 12.118 through 
12.127 and 127.28. Such persons must certify that they are in 
compliance with SNUR requirements. The EPA policy in support of the 
import certification appears at 40 CFR part 707.

III. Substances Subject to this Rule

    EPA is establishing significant new use and recordkeeping 
requirements for the following chemical substances under 40 CFR part 
721, subpart E. In this unit, EPA provides a brief description for each 
substance, including its PMN number, chemical name (generic name if the 
specific name is claimed as CBI), CAS number (if assigned for non-
confidential chemical identities), basis for the action taken by EPA in 
the TSCA section 5(e) consent order or as a non-section 5(e) SNUR for 
the substance (including the statutory citation and specific finding), 
toxicity concern, and the CFR citation assigned in the regulatory text 
section of this rule. The specific uses which are designated as 
significant new uses are cited in the regulatory text section of this 
document by reference to 40 CFR part 721, subpart E where the 
significant new uses are described in detail. Certain new uses, 
including production limits and other uses designated in the rule are 
claimed as CBI. The procedure for obtaining confidential information is 
set out in Unit VII.
    Where the underlying TSCA section 5(e) consent order prohibits the 
PMN submitter from exceeding a specified production limit without 
performing specific tests to determine the health or environmental 
effects of a substance, the tests are described in this unit. As 
explained further in Unit VI., the SNUR for such substances contains 
the same production limit, and exceeding the production limit is 
defined as a significant new use. Persons who intend to exceed the 
production limit must notify the Agency by submitting a significant new 
use notice (SNUN) at least 90 days in advance. In addition, this unit 
describes tests that are recommended by EPA to provide sufficient 
information to evaluate the substance, but for which no production 
limit has been established in the TSCA section 5(e) consent order. 
Descriptions of recommended tests are provided for informational 
purposes.
    Data on potential exposures or releases of the substances, testing 
other than that specified in the TSCA section 5(e) consent order for 
the substances, or studies on analogous substances, which may 
demonstrate that the significant new uses being reported do not present 
an unreasonable risk, may be included with significant new use 
notification. Persons submitting a SNUN must comply with the same 
notice requirements and EPA regulatory procedures as submitters of 
PMNs, as stated in 40 CFR 721.1(c), including submission of test data 
on health and environmental effects as described in 40 CFR 720.50.
    EPA is not publishing SNURs for PMNs for P-99-309, P-99-492/493/
494/495/496/497, P-99-847, P-99-1106, P-99-1166, and P-99 -1389, which 
are subject to a final TSCA section 5(e) consent order. The TSCA 
section 5(e) consent orders for these substances are derived from an 
exposure finding based solely on substantial production volume and 
significant or substantial human exposure and/or release to the 
environment of substantial quantities. For these cases there were 
limited or no toxicity data available for the PMN substances. In such 
cases, EPA regulates the new chemical substances under TSCA section 
5(e) by requiring certain toxicity tests. For instance, chemical 
substances with potentially substantial releases to surface waters 
would be subject to toxicity testing of aquatic organisms and chemicals 
with potentially substantial human exposures would be subject to health 
effects testing for mutagenicity, acute effects, and subchronic 
effects. However, for these substances, the short-term toxicity testing 
required by the TSCA section 5(e) consent order is usually completed 
within 1 to 2 years of notice of commencement (NOC). EPA's experience 
with exposure-based SNURs requiring short-term testing is that the SNUR 
is often revoked within 1 to 2 years when the test results are 
received. Rather than issue and revoke SNURs in such a short span of 
time, EPA will defer publication of exposure-based SNURs until either a 
NOC or data demonstrating risk are received unless the toxicity testing 
required is long-term. EPA is issuing this explanation and notification 
as required in 40 CFR 721.160(a)(2) as it has determined that SNURs are 
not needed at this time for these substances which are subject to a 
final section 5(e) consent order under TSCA.

PMN Numbers P-98-0082/0083/0084

[[Page 15065]]

Chemical names: (generic) (P-98-0082 and P-98-0083) Alkoxylated 
alkylpolyol acrylates, adduct with alkylamine and (generic) (P-98-0084) 
Alkoxylated alkylpolyol acrylates.
CAS numbers: Not available.
Basis for action: The PMN substances will be used as binders for UV or 
electron beam curable coatings for wood, paper, and plastics. Based on 
structural analogy to aliphatic amines, EPA is concerned that toxicity 
to aquatic organisms may occur at a concentration as low as 1 part per 
billion (ppb) of the PMN substances in surface waters. Since 
significant environmental exposure is not expected, as the substances 
are not released to surface waters, as described in the PMNs, EPA has 
not determined that the proposed manufacturing, processing, and use of 
the substances may present an unreasonable risk. EPA has determined, 
however, that other uses of the substances resulting in release to 
surface waters may cause significant adverse environmental effects. 
Based on this information the PMN substances meet the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substances. All tests should be conducted with the static methods and 
nominal concentrations.
CFR citation: 40 CFR 721.465.

PMN Numbers P-98-0497 and P-98-0509
Chemical name: Propanoic acid, 2-methyl-, (1R,2R,4R)-1,7,7-
trimethylbicyclo[2.2.1]hept-2-yl ester, rel-.
CAS number: 85586-67-0.
Basis for action: The PMN substances will be used as a fragrance 
compound for air fresheners, soaps, shampoo, household detergents, and 
bleach. Toxicity data on structurally similar esters indicate that the 
PMN substances may cause toxicity to aquatic organisms. Based on these 
data, EPA is concerned that toxicity to aquatic organisms may occur at 
a concentration of 10 ppb of the PMN substances in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substances are not released to surface waters in significant 
quantities, EPA has not determined that the proposed processing and use 
of the substances may present an unreasonable risk. EPA has determined, 
however, that an increase in production volume may result in releases 
of the PMN substances to surface waters which may cause significant 
adverse environmental effects. Based on this information the PMN 
substances meet the concern criteria at Sec.  721.170 (b)(4)(ii).
Recommended testing: The Agency has determined that an algal toxicity 
study (OPPTS 850.5400 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and a 
fish acute toxicity study (OPPTS 850.1075 test guideline (public 
draft)) would help to characterize possible environmental effects of 
the substances. The fish and daphnid tests should be conducted with 
flow-through methods and measured concentrations. The algal test should 
be conducted with static methods and measured concentrations.
CFR citation: 40 CFR 721.4486.

PMN Number P-98-0823
Chemical name: Dodecanoic acid, 12-amino-.
CAS number: 693-57-2.
Effective date of section 5(e) consent order: August 18, 2000.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and section 5(e)(1)(A)(ii) of TSCA based on a 
finding that this substance may present an unreasonable risk of injury 
to human health and the environment.
Toxicity concern: This PMN substance will be used as a raw material for 
Nylon-12. EPA has identified a health concern for carcinogenicity via 
inhalation exposure based on analogy to 11-aminoundodecanoic acid which 
caused neoplastic nodules in the liver and transitional cell carcinomas 
in the urinary bladder of male rats.
Recommended testing: EPA has determined that a carcinogenicity study 
(OPPTS 870.4200 test guideline) would help to characterize the human 
health effects.
CFR citation: 40 CFR 721.2584.

PMN Number P-98-1125
Chemical name: (generic) Fatty acid, reaction product with substituted 
oxirane, formaldehyde-phenol polymer glycidyl ether, substituted 
propylamine and polythylenepolyamines.
CAS number: Not available.
Basis for action: The PMN substance will be used as a curing agent for 
epoxy coating systems. Based on structural analogy to aliphatic amines, 
EPA is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 10 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 10 ppb, as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that other uses of the substance resulting 
in release to surface waters above 10 ppb may cause significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)); a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), an algal 
toxicity study (OPPTS 850.5400 test guideline (public draft)), and a 
fish acute toxicity mitigated by humic acid (`HA') of 10 and 20 mg HA 
per liter diluent would help to characterize the environmental effects 
of the PMN substance. All studies should use the static methods and 
nominal concentrations.
CFR citation: 40 CFR 721.6181.

PMN Number P-98-1262
Chemical name: (generic) Reaction product of alkylene diamine, MD1, 
substituted carbomonocyclic amine and alkylamine.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on test data on structurally similar neutral organic 
chemicals, the PMN substance may cause toxicity to aquatic organisms. 
Based on the data, EPA is concerned that toxicity to aquatic organisms 
may occur at a concentration as low as 1 ppb of the PMN substance in 
surface waters. Since significant environmental exposure is not 
expected, as the substance is not released to surface waters, as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that other uses of the 
substance resulting in release to surface waters may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the results of the 
following testing would help characterize the environmental effects of 
the PMN substance: a Melting point (OPPTS 830.7200 test guideline), a 
fish early-life stage toxicity test (OPPTS 850.1400 test guideline 
(public draft)), and a daphnid chronic toxicity test

[[Page 15066]]

(OPPTS 850.1300 test guideline (public draft)). The fish and daphnid 
tests should be conducted with the flow-through methods and measured 
concentrations, and hardness of dilution water less than 180 mg/L as 
CaC03.
CFR citation: 40 CFR 721.2582.

PMN Number P-99-0044
Chemical name: Formaldehyde, polymer with phenol and 1,2,3-
propanetriol, methylated.
CAS number: 209810-57-1.
Basis for action: The PMN substance will be used as a bonding agent for 
mineral aggregates. Based on structural analogy to phenols, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 3 ppb, as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that other uses of the substance resulting 
in releases to surface water above 3 ppb may cause adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that an activated sludge 
sorption isotherm test (OPPTS 835.1110 test guideline), a fish acute 
toxicity study (OPPTS 850.1075 test guideline (public draft)), a 
daphnid acute toxicity study (OPPTS 850.1010 test guideline (public 
draft)), and an algal toxicity study (OPPTS 850.5400 test guideline 
(public draft)) would help characterize the environmental effects of 
the PMN substance. The fish and daphid tests should be performed under 
flow through methods and measured concentrations. The algal test should 
be performed under static methods and measured concentrations.
CFR citation: 40 CFR 721.3807.

PMN Number P-99-0510
Chemical name: (generic) Hexamethylenediamine adduct of substituted 
piperidinyloxy.
CAS number: Not available.
Effective date of section 5(e) consent order: December 24, 1999.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and section 5(e)(1)(A)(ii)(i) of TSCA based on a 
finding that this substance may present an unreasonable risk of injury 
to human health.
Toxicity concern: Based on submitted data on a 28-day subchronic study 
in rats, the PMN substance has been shown to cause potential liver 
toxicity, hemolytic effects, and immunotoxicity from inhalation 
exposure to the PMN substance.
Recommended testing: A 90-day subchronic oral study in rats with 
emphasis on hematology, the immune system, and male reproductive system 
(OPPTS 870.3100 test guideline) would help to characterize possible 
effects of the substance. The PMN submitter has agreed not to exceed 
the production volume limit without performing the 90-day subchronic 
oral study.
CFR citation: 40 CFR 721.6205.

PMN Number P-99-0669
Chemical name: Oxirane, methyl-, polymer with oxirane, mono(3,5,5,-
trimethylhexyl) ether.
CAS number: 204336-40-3.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to nonionic surfactants, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration of 600 ppb in surface waters. Since significant 
environmental exposure is unlikely, as the substance is not released to 
surface waters, as described in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the substance may 
present an unreasonable risk. EPA has determined, however, that other 
uses of the substance resulting in releases to surface waters may cause 
significant adverse environmental effects. Based on this information 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substances. The fish and daphnid tests should be conducted with the 
flow-through methods and measured concentrations, and the algal test 
should be conducted with static methods and measured concentrations.
CFR citation: 40 CFR 721.522.

PMN Number P-99-0848
Chemical name: (generic) Alkenyl carboxylate, metal salt.
CAS number: Not available.
Effective date of section 5(e) consent order: August 2, 2000.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and section 5(e)(1)(A)(ii)(I) of TSCA based on a 
finding that this substance is expected to enter the environment in 
substantial quantities and may present an unreasonable risk of injury 
to the environment.
Toxicity concern: Based on analogy to anionic surfactants the PMN 
substance may be toxic to aquatic organisms at concentrations as low as 
1 ppb.
Recommended testing: EPA has determined that an algal toxicity study 
(OPPTS 850.5400 test guideline (public draft)), an daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
fish acute toxicity study (OPPTS 850.1075 test guideline (public 
draft)) would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations and hardness of dilution 
water with less than 180 mg/L as CaC03. The algal test 
should be conducted with static methods and measured concentrations. 
The PMN submitter has agreed not to exceed the production volume limit 
without performing these tests.
CFR citation: 40 CFR 721.2093.

PMN Number P-99-0873
Chemical name: (generic) Propanetriol polyalkylenepolyolamine aryl 
aldimine.
CAS number: Not available.
Basis for action: The PMN substance will be used as a binder for 
industrial coating. Based on additional information and structural 
analogy to schiff bases and aliphatic amines, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 2 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected, as the substance is not 
released to surface waters, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that other uses of the 
substance resulting in release to surface waters may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that an algal toxicity study 
(OPPTS 850.5400 test guideline (public draft)), a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid chronic 
toxicity study (OPPTS 850.1300 test guideline (public draft)) would 
help to characterize the environmental effects of the PMN substance. 
The fish and daphnid tests should be conducted with the flow-through 
methods and measured concentrations and the algal test should be 
conducted with static methods and measured concentrations.

[[Page 15067]]

CFR citation: 40 CFR 721.910.

PMN Number P-99-0874
Chemical name: (generic) Modified polymer of vinyl acetate and 
quaternary ammonium compound.
CAS number: Not available.
Basis for action: The PMN substance will be used as a modified 
polyvinyl alcohol. Based on submitted toxicity data for other high 
molecular weight, water swellable polymers, EPA has identified health 
concerns for inhalation exposure. Since significant inhalation exposure 
is unlikely when the substance is used as identified in the PMN, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that domestic manufacture of the PMN may lead to inhalation 
exposure which could cause serious health effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day inhalation 
toxicity study with a 60-day holding period (OPPTS 870.3465 test 
guideline) would help to characterize the human health effects of the 
PMN substance. Attention should be given to the lungs, including 
histopathology of the lungs (inflamation, epithelial hyperplasia, and 
fibrosis), bronchoalvelar lavage (BAL) analysis for markers of lung 
injury, and lung burden analysis for clearance of the test material 
(EPA-748-R-96-001). The neurotoxicity components and examination of 
organs other than the lungs are not required.
CFR citation: 40 CFR 721.8658.

PMN Number P-99-0965
Chemical name: Furan, octafluorotetrahydro-.
CAS number: 773-14-8.
Basis for action: The PMN substance will be used as heat transfer 
agent. EPA believes that other uses of the PMN substance are likely and 
they have the potential for more widespread environmental exposure 
causing potential atmospheric changes. EPA is concerned that such 
atmospheric changes may contribute to global warming. Since significant 
environmental exposure is unlikely, as described in the PMN, EPA has 

not determined that the proposed manufacturing, processing, and use of 
the substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the substance may result in significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that infrared absorption, 
destruction of OH by radical and rate of production of HF for global 
warming would help to characterize the atmospheric effects of the PMN 
substance.
CFR citation: 40 CFR 721.3818.

PMN Number P-99-0990
Chemical name: Cobaltate (5-), bis[4-[[6-[(4-amino-6-chloro-1,3,5-
triazin-2-yl)amio]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-3-hydroxy-7-
nitro-1-naphthalenesulfonato(4-)]-, pentasodium.
CAS number: 91144-26-2.
Basis for action: Based on structural analogues and submitted test 
data, EPA has identified health concerns for carcinogenicity and 
mutagenicity from inhalation exposure to the PMN substance. Since 
significant worker exposure is unlikely because inhalation exposure is 
not expected when the substance is used with protective equipment as 
identified in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that uses of the 
substance other than as described in the PMN may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(1)(i)(B) and (b)(1)(i)(C).
Recommended testing: EPA has determined that a combined chronic 
toxicity/carcinogenicity study (OPPTS 870.4300 test guideline) would 
help to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.5283.

PMN Number P-99-1167
Chemical name: L-aspartic acid, N,N'- [(1E) - 1,2 - ethenediylbis[(3-
sulfo-4, 1-phenylene)imino[6-(phenylamino)- 1,3,5-triazine-4,2 - 
diyl]]]bis-, hexasodium salt.
CAS number: 205764-98-3.
Basis for action: The PMN substance will be used as a fluorescent 
whitener for coated paper. Based on submitted test data, EPA has 
identified concerns for liver effects. Since significant worker 
exposure is unlikely because there would not be significant inhalation 
exposure for the use identified in the PMN, EPA has not determined that 
the proposed manufacturing, processing, and use of the substance as 
described in the PMN present an unreasonable risk. EPA has determined, 
however, that uses of the substance in a powder form or domestic 
manufacture may cause serious health effects. Based on this information 
the PMN substance meets the concern criteria at Sec.  721.170(b)(3)(i).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents (OPPTS 870.3100 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.4575.

PMN Number P-99-1189
Chemical name: 2-propenoic acid, 2-methyl-, C11-14-isoalkyl 
esters, C13-rich.
CAS number: 85736-97-6.
Basis for action: The PMN substance will be used as a monomer for 
casting automotive parts adhesives or as an impregnation fluid. Based 
on analogy to structurally similar methacrylates and esters, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected, as the 
substance is not released to surface waters above 1 ppb, as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that other uses of the substance resulting 
in release to surface waters above 1 ppb may cause significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: The Agency has determined that the results of the 
following testing would help to characterize possible environmental 
effects of the substance: A ready biodegradability test (OPPTS 835.3110 
test guideline); a fish early-life stage toxicity study (OPPTS 850.1400 
test guideline (public draft)); a mysid chronic toxicity study (OPPTS 
850.1350 test guideline (public draft)) for 21 days, flow-through 
methods and measured concentrations; and a saltwater algal toxicity 
study, tiers I and II (OPPTS 850.5400 test guideline (public draft)) 
with the static methods and measured concentrations.
CFR citation: 40 CFR 721.4792.

PMN Numbers P-99-1191 and P-99-1192
Chemical name: (generic) Rare earth phosphate.
CAS number: Not available.
Basis for action: The PMN substances will be used as phosphors. Based 
on structural analogy to soluble salts and test data for inorganic 
phosphates, EPA is concerned that toxicity to aquatic organisms may 
occur at a concentration as low as 2 ppb of the PMN substances in 
surface waters. Since significant environmental exposure is not 
expected, as the substances are not released to

[[Page 15068]]

surface waters above 10 ppb, as described in the PMNs, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substances may present an unreasonable risk. EPA has determined, 
however, that other uses of the substances resulting in release to 
surface waters above 10 ppb may cause significant adverse environmental 
effects. Based on this information the PMN substances meet the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substances. A flow-through method with measured concentrations of the 
rare earth metal is recommended for the fish and daphnid study and the 
static method with measured concentrations for green algae. In 
addition, the test dilution water and/or test medium should have a 
measured hardness of less than 180.0 mg/L as CaC03 and a 
total organic carbon (TOC) concentration of less than 2.0 mg TOC/L.
CFR citation: 40 CFR 721.6005.

PMN Number P-99-1287
Chemical name: (generic) Alkylaminated polyolefin.
CAS number: Not available.
Basis for action: The PMN substance will be used as a gasoline fuel 
additive. Based on structural analogy to aliphatic amines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 40 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected, as the 
substance is not released to surface waters, as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the substance resulting in 
release to surface waters may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. These tests should be conducted with static methods and 
nominal concentrations, total organic carbon TOC of dilution water < 
2.0 mg TOC/L, hardness of dilution water < 180.0 mg/L as 
CaC03, and stock solution adjusted to pH 7.0 with HCl.
CFR citation: 40 CFR 721.6178.

PMN Number P-99-1327
Chemical name: Propane, 1,1,1,3,3-pentachloro-.
CAS number: 23153-23-3.
Basis for action: The PMN substance will be used as an intermediate for 
hydrofluorocarbon production. Based on submitted test data, EPA has 
identified health concerns for carcinogenicity, liver and kidney 
toxicity. Based on submitted data on hexachloropropane, concern for 
immunotoxicity was identified. Also, the Agency identified concern for 
neurotoxicity, reproductive toxicity in males and females, and concern 
for irritation and lesions in nasal passages and respiratory passages 
based on test data on other structural analogues. Since significant 
worker exposure is unlikely when the substance is used as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that use of the substance other than as 
described in the PMN could result in exposures which may cause serious 
health effects. Based on this information the PMN substance meets the 
concern criteria at Sec.  721.170(b)(1)(i)(A), (b)(3)(i), and 
(b)(3)(ii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study (OPPTS 870.3700 test guideline), carcinogenicity study 
(OPPTS 870.4200 test guideline), and a reproduction fertility effects 
study (OPPTS 870.3800 test guideline) by the inhalation route will help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.533.

PMN Number P-99-1346
Chemical name: Silane, triethoxy (3,3,4,4,5,5,6,6,7,7,8,8,8-
tridecafluorooctyl)-.
CAS number: 51851-37-7.
Basis for action: The PMN substance will be used as in anti-graffiti 
coatings as described in the PMN. Based on structural analogy to 
alkoxysilanes, EPA has identified health concerns for lung toxicity. 
Since significant worker exposure is unlikely, when the substance is 
used with protective equipment as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that use of the PMN substance other than as described in the 
PMN could result in exposures which may cause serious health effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation toxicity study in rats (OPPTS 870.3465 test guideline) would 
help to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.9504.

PMN Number P-99-1366
Chemical name: (generic) 4,6-Disubstituted pyrimidine.
CAS number: Not available.
Basis for action: The PMN substance will be used as a starting material 
for synthesis of a chemical intermediate. EPA has identified health 
concerns for neurotoxicity and immunotoxicity (effects to the spleen) 
based on test data on an analogous substance, concerns for 
carcinogenicity and developmental toxicity based on the potential for 
the PMN substance to act as an arylating agent or as an antimetabolite. 
Since significant worker exposure is unlikely, when the substance is 
used as described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture could result in exposures which may cause serious chronic 
and developmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(ii) and (b)(1)(i)(C).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents (OPPTS 870.3100 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.8920.

PMN Number P-99-1399
Chemical name: (generic) Aromatic epoxide resin.
CAS number: Not available.
Basis for action: The PMN substance will be used as a thermoset resin. 
EPA has identified health concerns for mutagenicity, carcinogenicity, 
developmental toxicity, male reproductive effects, liver and kidney 
toxicity based on the epoxide groups. Since significant worker exposure 
is unlikely, when the substance is used as described in the PMN, EPA 
has not determined that the proposed

[[Page 15069]]

manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that use of the PMN 
substance other than as described in the PMN may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents with attention to pathology of the 
reproductive organs (OPPTS 870.3100 test guideline), a reproduction 
fertility effects study (OPPTS 870.3800 test guideline), and a combined 
chronic toxicity/carcinogenicity study (OPPTS 870.4300 test guideline) 
would help to characterize the health effects of the substance.
CFR citation: 40 CFR 721.2673.

PMN Number P-00-0045
Chemical name: (generic) Benzenediazonium, [[[[(substituted) 
azo]phenyl]sulfonyl]amino]-, coupled with aminophenol, diazotized 
aminobenzoic acid, diazotized (substituted) benzenesulfonic acid and 
naphthalenol.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on submitted test data, EPA has identified health concerns 
for methemoglobinemia. Since significant worker exposure is unlikely 
when used as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing, and use of the substance may cause 
significant adverse effects. EPA has determined, however, that domestic 
manufacture may result in serious health effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents (OPPTS 870.3100 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.5286.

PMN Number P-00-0067
Chemical name: (generic) Alkyl heteropolycyclic-aniline.
CAS number: Not available.
Basis for action: The PMN substance will be used as an industrial 
intermediate. Based on test data and on structural analogy to anilines, 
EPA is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the 
substance is not released to surface water above 1 ppb as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that other uses of the substance resulting 
in release to surface above 1 ppb may cause significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(i) and (b)(4)(ii).
Recommended testing: EPA has determined that a daphnid chronic toxicity 
test (OPPTS 850.1300 test guideline (public draft)), a fish early-life 
stage toxicity test (OPPTS 850.1400 test guideline (public draft)) 
conducted with flow-through methods and measured concentrations, 
dilution water hardness < 180.0 mg/L as CaC03, and a Porous 
Pot (OPPTS 835.3220 test guideline) would help to characterize the 
environmental effects.
CFR citation: 40 CFR 721.4136.

PMN Number P-00-0094
Chemical name: (generic) Salt of a substituted sulfonated aryl azo 
compound.
CAS number: Not available.
Basis for action: The PMN substance will be used as a colorant for 
coating compositions. EPA has identified health concerns for testicular 
effects, blood effects, and liver toxicity based on submitted test 
data. Since significant worker exposure is unlikely, when the substance 
is used as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing, and use of the substance may 
present an unreasonable risk. EPA has determined however, that domestic 
manufacture could result in exposures which may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(i).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents (OPPTS 870.3100 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.9597.

PMN Number P-00-0108
Chemical name: (generic) Alkoxyamino-alkyl-coumarin.
CAS number: Not available.
Basis for action: The PMN substance will be used as a chemical tracer. 
Based on structural analogy to coumarins, EPA has identified health 
concerns for developmental toxicity and carcinogenicity. Since 
significant worker exposure is unlikely when the substance is used as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture could result in exposures which may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii) and (b)(1)(i)(C).
Recommended testing: EPA has determined that a 90-day subchronic oral 
study in rodents (OPPTS 870.3100 test guideline) and a prenatal 
developmental toxicity study (OPPTS 870.3700 test guideline) would help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.2155.

PMN Number P-00-0202
Chemical name: (generic) Reaction product of substituted aromatic diol, 
formaldehyde and alkanolamine, propoxylated.
CAS number: Not available.
Basis for action: The PMN substance will be used as foam insulation. 
Based on structural analogy to aliphatic amines, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 10 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected, as the substance is not 
released to surface waters, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the substance resulting in release to 
surface water may cause significant adverse environmental effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. All tests should be conducted with static methods and 
nominal concentrations, dilution water total organic carbon TOC < 2.0 
mg TOC/L dilution water hardness < 180.0 mg/L as CaC03, and 
stock solution adjusted to pH 7.0.
CFR citation: 40 CFR 721.8085.

PMN Number P-00-0330
Chemical name: Oxirane, [[[(1R,2S,5R)-5-methyl-2-(1-
methylethyl)cyclohexyl]oxy]methyl]-.
CAS number: 249297-16-3.

[[Page 15070]]

Basis for action: The PMN substance will be used as a chemical 
intermediate. Based on data for monoepoxides, EPA has identified health 
concerns for mutagenicity, carcinogenicity, male reproductive toxicity, 
developmental toxicity, and liver and kidney toxicity for the epoxide. 
Also, based on analogy to epoxides, EPA is concerned that toxicity to 
aquatic organisms may occur at a concentration as low as 30 ppb of the 
PMN substance in surface waters. Since significant worker and 
environmental exposure is unlikely when the substance is used as 
described in the PMN, EPA has not determined that the manufacturing, 
processing, and use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that use of the substance other than 
as an intermediate could result in exposures which may cause serious 
health effects and significant adverse environmental effects. Based on 
this information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii), (b)(1)(i) (C), and (b)(4)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
toxicity study in rodents (OPPTS 870.3100 test guideline), with 
attention to pathology of the reproductive organs, and a 
carcinogenicity study (OPPTS 870.4200 test guideline) would help to 
characterize the health effects of the substance. In addition, the 
following acute aquatic toxicity tests would help to characterize the 
environmental effects. A fish acute toxicity study (OPPTS 850.1075 test 
guideline (public draft)), a daphnid acute toxicity study (OPPTS 
850.1010 test guideline (public draft)), and an algal toxicity study 
(OPPTS 850.5400 test guideline (public draft)). The fish and daphnid 
tests should be conducted with flow-through methods and measured 
concentrations. The algal test should be conducted with static methods 
and measured concentrations.
CFR citation: 40 CFR 721.5590.

PMN Numbers P-00-0333 and P-00-0334
Chemical name: (generic) Salt of an acrylate copolymer.
CAS number: Not available.
Basis for action: The PMN substances will be used as an additive. EPA 
has identified concerns for lung toxicity and lung tumors based on data 
on certain high molecular weight polymers. Since significant worker 
exposure is unlikely as inhalation exposure is not expected for the 
uses described in the PMNs, EPA has not determined that the proposed 
manufacturing, processing, and use of the substances may present an 
unreasonable risk. EPA has determined, however, that uses of the 
substances in a solid form may cause serious health effects. Based on 
this information the PMN substances meet the concern criteria at Sec.  
721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day inhalation 
toxicity study with a 60-day holding period (OPPTS 870.3465 test 
guideline) would help characterize the human health effects of the PMN 
substance. Attention should be given to the lungs, including 
histopathology of the lungs (inflamation, epithelial hyperplasia, and 
fibrosis), bronchoalvelar lavage (BAL) analysis for markers of lung 
injury, and lung burden analysis for clearance of the test material 
(EPA-748-R-96-001). The neurotoxicity components and examination of 
organs other than the lungs are not required.
CFR citation: 40 CFR 721.338.

PMN Number P-00-0351
Chemical name: (generic) Amino-hydroxy sulfonaphthylazo-disubstituted 
phenyl azo benzene carboxylate salt.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on submitted data on a 28-day study in rats with a no 
observed adverse effect level (NOAEL) of 25 mg/kg/day, EPA has 
identified concerns for liver and kidney effects. Additionally, based 
on analogy of the azo reduction product of the PMN substance, EPA has 
concerns for carcinogenicity, developmental toxicity, and 
immunotoxicity. Since significant worker exposure is unlikely as 
inhalation exposure is not expected for the use described in the PMN, 
EPA has not determined that manufacturing, processing, and use of the 
substance as described in the PMN may present an unreasonable risk. EPA 
has determined, however, that use of the substance as a solid may cause 
serious health effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(ii), (b)(3)(iii), and 
(b)(1)(i)(D).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in two species (OPPTS 870.3700 test 
guideline) and an Ames assay with the Prival modification and a 
concurrent positive control (OPPTS 870.5100 test guideline) would help 
to characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.984.

PMN Number P-00-0353
Chemical name: (generic) Alkoxylated aliphatic diisocyanate allyl 
ether.
CAS number: Not available.
Basis for action: The PMN substance will be used as an additive for 
surface coatings and for plastics and plastic surfaces. Based on 
structural analogy to esters and allylic and vinyl ethers, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 9 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected, as the PMN 
substance is not released to surface waters, as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the substance resulting in 
release to surface waters may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish chronic toxicity 
study (OPPTS 850.1400 test guideline (public draft)), a daphnid chronic 
toxicity study (OPPTS 850.1300 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations, dilution water hardness 
less than 180.0 mg/L as CaC03. The algal test should be 
conducted with static methods and measured concentrations.
CFR citation: 40 CFR 721.9952.

PMN Numbers P-00-0364 and P-00-0365
Chemical name: (generic) Copper complex of (substituted sulfonaphthyl 
azo substituted phenyl) disulfonaphthyl azo, amine salt.
CAS number: Not available.
Basis for action: The PMN substances will be used as described in the 
PMNs. Based on analogy to structurally similar substances, EPA has 
identified concerns for mutagenicity, carcinogenicity, and 
developmental toxicity. Since significant worker exposure is unlikely 
as inhalation exposure is not expected for the uses described in the 
PMNs, EPA has not determined that the proposed manufacturing, 
processing, and use of the substances may present an unreasonable risk. 
EPA has determined, however, that use of the substances as a powder may 
cause serious health effects. Based on this information the PMN 
substances meet the concern criteria at Sec.  721.170(b)(3)(ii) and 
(b)(1)(i)(C).
Recommended testing: EPA has determined that a prenatal

[[Page 15071]]

developmental toxicity study by the oral route in two species (OPPTS 
870.3700 test guideline) would help to characterize the human health 
effects of the PMN substance.
CFR citation: 40 CFR 721.2577.

PMN Number P-00-0420
Chemical name: (generic) Substituted phenylazophenylazo phenol.
CAS number: Not available.
Basis for action: The PMN substance will be used as a colorant. Based 
on structural analogy to phenols, EPA is concerned that toxicity to 
aquatic organisms may occur at a concentration as low as 1 ppb of the 
PMN substance in surface waters. Since significant environmental 
exposure is not expected, as the substance is not released to surface 
waters, as described in the PMN, EPA has not determined that the 
proposed manufacturing, processing and use of the substance may present 
an unreasonable risk. EPA has determined, however, that other uses of 
the substance resulting in release to surface water may cause 
significant adverse environmental effects. Based on this information 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations. The algal test should be 
conducted with static methods and measured concentrations. Dilution 
water hardness less than 180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.843

PMN Number P-00-0469
Chemical name: Glycine, N-(carboxymethyl)-N-dodecyl-, monosodium salt.
CAS number: 141321-68-8.
Basis for action: The PMN substance will be used as a surfactant. Based 
on structural analogy to alkyl amphoteric surfactants, EPA is concerned 
that toxicity to aquatic organisms may occur at a concentration as low 
as 30 ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected as the PMN substance is not 
released to surface water above 30 ppb, as described in the PMN, EPA 
has not determined that the proposed manu-facturing, processing, and 
use of the substance may present an unreasonable environmental risk. 
EPA has determined, however, that other uses of the substance resulting 
in release to surface water above 30 ppb may cause significant adverse 
environmental effects. Based on this infor-mation the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the following acute 
aquatic toxicity tests would help to characterize the environmental 
effects: a fish acute toxicity study (OPPTS 850.1075 test guideline 
(public draft)), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline (public draft)), and an algal toxicity study (OPPTS 850.5400 
test guideline (public draft)). The fish and daphnid tests should be 
conducted with flow-through methods and measured concentrations. The 
algal test should be conducted with static methods and measured 
concentrations, dilution water total organic carbon TOC < 2.0 mg TOC/L 
dilution water hardness < 180.0 mg/L as CaC03, and stock 
solution adjusted to pH 7.0.
CFR citation: 40 CFR 721.3848.

PMN Number P-00-0490
Chemical name: (generic) Substituted acrylamides and acrylic acid 
copolymer.
CAS number: Not available.
Basis for action: The PMN substance will be used as a delivery 
substrate. EPA has identified concerns for lung toxicity and 
carcinogenicity if the substance is inhaled based on data for certain 
high molecular weight polymers. Since significant worker exposure is 
unlikely as inhalation exposure to worker is not expected for the use 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substances may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture, or processing and use of the substance in a powder form 
may cause serious health effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(ii) and 
(b(1)(i)(C).
Recommended testing: EPA has determined that a 90-day inhalation 
toxicity study with a 60-day holding period (OPPTS 870.3465 test 
guideline) would help characterize the human health effects of the PMN 
substance. Attention should be given to the lungs, including 
histopathology of the lungs (inflamation, epithelial hyperplasia, and 
fibrosis), bronchoalvelar lavage (BAL) analysis for markers of lung 
injury, and lung burden analysis for clearance of the test material 
(EPA-748-R-96-001). The neurotoxicity components and examination of 
organs other than the lungs are not required.
CFR citation: 40 CFR 721.321.

PMN Number P-00-0542
Chemical name: (generic) Substituted phenols and formaldehyde polymer, 
alkylated.
CAS number: Not available.
Basis for action: The PMN substance will be used as a resin for can and 
tube coatings. Based on structural analogy to polyphenol reaction 
products, EPA is concerned that toxicity to aquatic organisms may occur 
at a concentration as low as 4 ppb of the PMN substance in surface 
waters. Since significant environmental exposure is unlikely, as the 
substance is not released to surface waters, as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the substance may prevent an unreasonable risk. EPA has 
determined, however, that other uses of the substance resulting in 
releases to surface waters may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentration. The algal test should be 
conducted with static methods and measured concentration. Dilution 
water hardness < 180 mg/L as CaC03.
CFR citation: 40 CFR 721.3812.

PMN Number P-00-0559
Chemical name: (generic) Methylated-para-rosaniline salt of a 
trisulfonated triarylmethane dye.
CAS number: Not available.
Basis for action: The PMN substance will be used as a colorant for 
inks. EPA has identified health concerns for carcinogenicity and 
developmental toxicity based on analogy to gentian violet. Since 
significant worker exposure is unlikely when the substance is used as 
described in the PMN, EPA has not determined that the proposed 
processing and use of the substance may present a unreasonable risk. 
EPA has determined however, that domestic manufacturing could result in 
exposures which may cause serious health effects. Also, based on 
analogy to cationic dyes. EPA is also concerned that toxicity to 
aquatic organisms may occur at a concentration as low as 2 ppb of the

[[Page 15072]]

PMN substance in surface waters. Since significant environmental 
exposure is not expected as the PMN substance is not released to 
surface water above 2 ppb, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable environmental risk. EPA has 
determined, however, that other uses of the substance resulting in 
release to surface water above 2 ppb may cause significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170 (b)(1)(i)(C), (b)(3)(ii), 
and (b)(4)(ii).
Recommended testing: EPA has determined that the following acute 
aquatic toxicity tests would help to characterize the environmental 
effects: a fish acute toxicity study (OPPTS 850.1075 test guideline 
(public draft)), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline (public draft)), and an algal toxicity study (OPPTS 850.5400 
test guideline (public draft)). The fish and daphnid tests should be 
conducted with flow-through methods and measured concentrations, 
dilution water total organic carbon TOC < 2.0 mg TOC/L. The algal test 
should be conducted with static methods and measured concentration. 
Dilution water hardness < 180.0 mg/L as CaC03. EPA has also 
determined that a prenatal developmental toxicity study by the oral 
route in two-species (OPPTS 870.3700 test guideline) would help to 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.9520.

PMN Number P-00-0618
Chemical name: (generic) Substituted hydroxyalkane acetate.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has concerns for liver toxicity, kidney toxicity, and 
developmental toxicity based on a 28-day subchronic inhalation study in 
rats and a developmental toxicity study in rats for an analog of the 
PMN material; EPA identified concerns for neurotoxicity and 
carcinogenicity based on analog data. Since significant worker exposure 
is unlikely as inhalation exposure is not expected for the use 
described in the PMN, EPA has not determined that manufacturing, 
processing, and use of the substance as described in the PMN may 
present an unreasonable risk. EPA has determined, however, that use of 
the substance other than as described in the PMN may cause serious 
health effects. Based on this information the PMN substance meets the 
concern criteria at Sec.  721.170 (b)(3)(i), (b)(3)(ii), and 
(b)(1)(i)(C).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in two species (OPPTS 870.3700 test 
guideline) and a 90-day inhalation toxicity study with a 60-day holding 
period (OPPTS 870.3465 test guideline) would help to characterize the 
human health effects of the PMN substance.
CFR citation: 40 CFR 721.532.

PMN Number P-00-0626
Chemical name: (generic) Acrylate of polymer based on isophorone 
diisocyanate.
CAS number: Not available.
Basis for action: The PMN substance will be used as an additive for 
inks and coatings. Based on structural analogy to acrylates, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 3 ppb, as described in 
the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable 
environmental risk. EPA has determined, however, that other uses of the 
substance resulting in release to surface water above 3 ppb may cause 
significant adverse environmental effects. Based on this information 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
Recommended testing: EPA has determined that the following acute 
aquatic toxicity tests would help to characterize the environmental 
effects: a fish acute toxicity study (OPPTS 850.1075 test guideline 
(public draft)), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline (public draft)), and an algal toxicity study (OPPTS 850.5400 
test guideline (public draft)). The fish and daphnid tests should be 
conducted with flow-through methods and measured concentrations The 
algal test should be conducted with static methods and measured 
concentrations. Dilution water hardness < 180.0 mg/L as 
CaC03.
CFR citation: 40 CFR 721.463.

PMN Number P-00-0637
Chemical name: Methylium, triphenyl-, tetrakis(pentafluorophenyl)borate 
(l-).
CAS number: 136040-19-2.
Basis for action: The use of the substance is as described in the PMN. 
Based on structural analogy to organoborates, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected, as the substance is not 
released to surface waters, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the substance resulting in release to 
surface waters may cause significant adverse environmental effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations. The algal test should be 
conducted with static methods and measured concentrations. Dilution 
water hardness less than 180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.5454.

PMN Number P-00-0638
Chemical name: (generic) Alkali metal salt of halogenated organoborate.
CAS number: Not available.
Basis for action: The use of the substance is as described in the PMN. 
Based on structural analogy to organoborates, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 3 
ppb of the PMN substances in surface waters. Since significant 
environmental exposure is not expected, as the substance is not 
released to surface waters, as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the substance resulting in release to 
surface waters may cause significant adverse environmental effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and

[[Page 15073]]

daphnid tests should be conducted with flow-through methods and 
measured concentrations. The algal test should be conducted with static 
methods and measured concentrations. Dilution water hardness less than 
180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.5452.

PMN Number P-00-0691
Chemical name: Amides, from ammonium hydroxide - maleic anhydride 
polymer and hydrogenated tallow alkyl amines, sodium salts, compds. 
with ethanolamine.
CAS number: 208408-03-1.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to anionic surfactants. EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 80 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 80 ppb, as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, other uses of the substance resulting in 
release to surface waters above 80 ppb may cause significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the following acute 
aquatic toxicity tests would help to characterize the environmental 
effects: a fish acute toxicity study (OPPTS 850.1075 test guideline 
(public draft)), a daphnid acute toxicity study (OPPTS 850.1010 test 
guideline (public draft)), and an algal toxicity study (OPPTS 850.5400 
test guideline (public draft)). The fish and daphnid tests should be 
conducted with flow-through methods and measured concentrations. The 
algal test should be conducted with static methods and measured 
concentrations. Dilution water hardness < 180.0 mg/L as 
CaC03.
CFR citation: 40 CFR 721.6183.

PMN Number P-00-0698
Chemical name: (generic) Lithium salt of a sulfophenyl azo phenyl azo 
disulfostilbene.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on analogy to structurally similar substance, EPA has 
identified concerns for liver toxicity, developmental toxicity, 
neurotoxicity, and blood toxicity for the aromatic amine azo reduction 
product. Since significant worker exposure is unlikely as inhalation 
exposure is not expected for the uses described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that use of the substance as a solid may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(iii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in two species (OPPTS 870.3700 test 
guideline) and a 90-day subchronic oral toxicity study in rodents 
(OPPTS 870.3100 test guideline) would help to characterize the human 
health effects of the PMN substance.
CFR citation: 40 CFR 721.9538.

PMN Number P-00-0738
Chemical name: Formaldehyde, reaction products with 1,3-
benzenedimethanamine and bisphenol A.
CAS number: 259871-68-6.
Basis for action: The PMN substance will be used as coatings for 
railcars and marine vessels. Based on structural analogy to phenols and 
aliphatic amines, EPA is concerned that toxicity to aquatic organisms 
may occur at a concentration as low as 20 ppb of the PMN substance in 
surface waters. Since significant environmental exposure is not 
expected as the PMN substance is not released to surface waters, as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that other uses of the 
substance resulting in releases to surface waters may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. These tests should be conducted with the static methods and 
nominal concentrations, dilution water total organic carbon TOC < 2.0 
mg TOC/L dilution water hardness < 180.0 mg/L as CaC03, and 
stock solution adjusted to pH 7.0. EPA has also determined that an 
activated sludge isotherm test (OPPTS 835.1110 test guideline) would 
help to characterize the environmental fate of the PMN substance.
CFR citation: 40 CFR 721.3805.

PMN Number P-00-0789
Chemical name: 1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 
1,4 - butanediol, cyclized.
CAS number: 263244-54-8.
Basis for action: The PMN substance will be used as a curable 
thermoplastic resin. EPA has identified health and environmental 
concerns because the substance is potentially a persistent, 
bioaccumulative, and toxic (PBT) chemical, EPA estimates that the PMN 
substance will persist in the environment more than two months and 
estimates a bioaccumulation factor of greater than or equal to 1,000. 
Also based on structural analogy to esters, EPA expects toxicity to 
aquatic organisms at surface water concentrations as low as 9 ppb. 
Since significant environmental exposure is not expected as the 
substance is not released to surface waters, described in the PMN, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the substance resulting in release to 
surface water may cause significant adverse environmental effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemicals Program's PBT Policy 
Statement (63 FR 60194; November 4, 1999) (FRL-6097-7) would help to 
characterized the properties of the substance. EPA has also determined 
that the following aquatic toxicity tests: a fish chronic toxicity 
study (OPPTS 850.1400 test guideline (public draft)), a daphnid chronic 
toxicity study (OPPTS 850.1300 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations. The algal test should be 
conducted with static methods and measured concentrations. Dilution 
water hardness < 180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.990.

PMN Number P-00-0803
Chemical name: (generic) 2,7-Naphthalenedisulfonic acid, 5-[[4-chloro-
6-[substituted] amino]-1,3,5-

[[Page 15074]]

triazin-2-yl]amino]-4-hydroxy-3-[(1-sulfo-2-naphthalenyl)azo]-, 
trisodium salt.
CAS number: Not available.
Basis for action: The PMN substance will be used as a textile dye. EPA 
has identified health concerns for mutagenicity and developmental 
toxicity based on one of the substituents on an azo reduction product. 
Since significant worker exposure is unlikely when the substance is 
used as described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture could result in exposures which may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(iii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in rats (OPPTS 870.3700 test 
guideline) would help to characterize the human health effects of the 
PMN substance.
CFR citation: 40 CFR 721.5262.

PMN Number P-00-0806
Chemical name: 1,3,6-Naphthalenetrisulfonic acid, 7-[[2-
[(aminocarbonyl)amino]-4-[[4-[[2-[2-
(ethenylsulfonyl)ethoxy]ethyl]amino]-6-fluoro-1,3,5-triazin-2-
yl]amino]phenyl]azo], trisodium salt.
CAS number: 106359-91-5.
Basis for action: The PMN substance will be used as a textile dye. 
Based on submitted test data, EPA has identified health concerns for 
mutagenicity, dermal sensitization and possible irreversible cornea 
staining; developmental toxicity and carcinogenicity based on one of 
the substituents on an azo reduction product. Since significant worker 
exposure is unlikely when the substance is used as described in the 
PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that domestic manufacture could result in 
exposures which may cause serious health effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i), (b)(l)(i)(D), and (b)(3)(iii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity study by the oral route in rats (OPPTS 870.3700 test 
guideline) would help to characterize the human health effects of the 
PMN substance.
CFR citation: 40 CFR 721.5260.

PMN Number P-00-0816
Chemical name: (generic) Alkyl dialkylamino phenylsulfonyl alkenoate.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on test data for structurally similar compounds, EPA has 
identified health concerns for kidney and liver toxicity. Since 
significant worker exposure is unlikely when the substance is used as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture could result in exposures which may cause serious health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(i). Also, based on structural analogy 
to aliphatic amines, acrylates, and allylic and vinyl sulfones, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the 
substance is not released to surface waters, as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the substance resulting in 
release to surface waters may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
study in rats (OPPTS 870.3100) would help characterize the human health 
effects of the PMN substance. Also the following aquatic toxicity test 
would help characterize the environmental effects of the PMN substance: 
a fish acute toxicity study (OPPTS 850.1075 test guideline (public 
draft)), a daphnid acute toxicity study (OPPTS 850.1010 test guideline 
(public draft)), and an algal toxicity study (OPPTS 850.5400 test 
guideline (public draft)). The fish and daphnid tests should be 
conducted with flow-through methods and measured concentrations. The 
algal test should be conducted with static methods and measured 
concentrations, dilution water total organic carbon TOC < 2.0 mg TOC/L 
dilution water hardness < 180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.648.

PMN Number P-00-0827
Chemical name: 1-propanol, 3-propoxy-.
CAS number: 4161-22-2.
Basis for action: The PMN substance will be used as described in the 
PMN. EPA has identified health concerns for liver toxicity based on 
submitted test data and neurotoxicity based on the solvent properties 
of the substance. Since significant worker exposure is unlikely, when 
the substance is used with protective equipment as described in the 
PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that use of the substance other than as 
described in the PMN including handling the material without the use of 
impervious gloves could result in exposures which may cause serious 
health effects. Based on this information the PMN substance meets the 
concern criteria at Sec.  721.170(b)(3)(i) and (b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
study (OPPTS 870.3100 test guideline), and a prenatal developmental 
toxicity study (OPPTS 870.3700 test guideline) would help to 
characterize the health effects of the substance.
CFR citation: 40 CFR 721.525.

PMN Number P-00-0922
Chemical name: Borate(1-), tris(acetato-.kappa.O)hydro-, sodium, (T-
4)-.
CAS number: 56553-60-7.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to other boron compounds, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 300 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 300 ppb, as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that other uses of the substance resulting 
in release to surface water above 300 ppb may cause significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170 (b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to

[[Page 15075]]

characterize the environmental effects of the PMN substance. The fish 
and daphnid tests should be conducted with flow-through methods and 
measured concentrations. The algal test should be conducted with static 
methods and measured concentrations. Dilution water hardness less than 
180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.1880.

PMN Number P-00-0993
Chemical name: (generic) Substituted 6,6'-(1-methylethylidene)bis[3,4-
dihydro-3-phenyl-1,3-benzoxazine].
CAS number: Not available.
Basis for action: The PMN substance will be used as resin for 
structural composites and electronic laminates. EPA has identified 
health and environmental concerns because the substance is potentially 
a PBT chemical. Since significant environmental exposure is not 
expected, as the substance is not released to surface waters, as 
described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that other uses of the 
substance resulting in releases to surface waters may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that the results of the tiered 
testing as described in the New Chemicals Program's PBT Category (63 FR 
60194; November 4, 1999) would help to characterized the properties of 
the substance. EPA has also determined that the results of the 
following aquatic toxicity tests: a fish chronic toxicity study (OPPTS 
850.1400 test guideline (public draft)), a daphnid chronic toxicity 
study (OPPTS 850.1300 test guideline (public draft)), and an algal 
toxicity study (OPPTS 850.5400 test guideline (public draft)), would 
help to characterize the environmental effects of the PMN substance. 
The fish and daphnid tests should be conducted with flow-through 
methods and measured concentrations, dilution water hardness < 180.0 
mg/L as CaC03. The algal test should be conducted with 
static methods and measured concentrations.
CFR citation: 40 CFR 721.1767

PMN Number P-00-1086
Chemical name: (generic) Silyl amine, potassium salt.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to aliphatic amines, EPA is concerned 
that toxicity to aquatic organisms may occur at a concentration as low 
as 10 ppb of the PMN substance in surface waters. Since significant 
environmental exposure is not expected as the PMN substance is not 
released to surface waters as described in the PMN, EPA has not 
determined that the proposed manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that other uses of the substance resulting in release to 
surface waters may cause significant adverse environmental effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170 (b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentrations. The algal test should be 
conducted with static methods and measured concentrations, dilution 
water total organic carbon TOC < 2.0 mg TOC/L dilution water hardness < 
180.0 mg/L as CaC03.
CFR citation: 40 CFR 721.638.

PMN Number P-00-1087
Chemical name: (generic) Di-alkyl borane.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to organoborane compounds, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 200 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected as the PMN 
substance is not released to surface water above 200 ppb, as described 
in the PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may present an unreasonable risk. 
EPA has determined, however, that other uses of the substance resulting 
in release to surface waters above 200 ppb may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentration. The algal test should be 
conducted with static methods and measured concentration. Dilution 
water hardness < 180 mg/L as CaC03.
CFR citation: 40 CFR 721.1852.

PMN Number P-00-1089
Chemical name: (generic) Alkali metal alkyl borohydride.
CAS number: Not available.
Basis for action: The PMN substance will be used as described in the 
PMN. Based on structural analogy to organoborane compounds, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 300 ppb of the PMN substance in surface waters. 
Since significant environmental exposure is not expected, as the 
substance is not released to surface waters as described in the PMN, 
EPA has not determined that the proposed manufacturing, processing, and 
use of the substance may present an unreasonable risk. EPA has 
determined, however, that other uses of the substance resulting in 
release to surface waters may cause significant adverse environmental 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (OPPTS 850.1075 test guideline (public draft)), a daphnid acute 
toxicity study (OPPTS 850.1010 test guideline (public draft)), and an 
algal toxicity study (OPPTS 850.5400 test guideline (public draft)) 
would help to characterize the environmental effects of the PMN 
substance. The fish and daphnid tests should be conducted with flow-
through methods and measured concentration. The algal test should be 
conducted with static methods and measured concentration. Dilution 
water hardness < 180 mg/L as CaC03.
CFR citation: 40 CFR 721.1878.

PMN Number P-00-1132
Chemical name: (generic) Siloxanes and silicones, aminoalkyl, 
fluorooctyl, hydroxy-terminated salt.
CAS number: Not available.
Basis for action: The PMN substance will be used in anti-graffiti 
systems as described in the PMN. Based on structural analogy to 
perfluoro alkyl polycationic polymers, EPA has identified health 
concerns for lung toxicity from inhalation exposure. Since

[[Page 15076]]

significant worker exposure is unlikely when used as described in the 
PMN, EPA has not determined that the proposed manufacturing, 
processing, and use of the substance may cause significant adverse 
effects. EPA has determined, however, that use of the PMN substance 
other than as described in the PMN could result in exposures which may 
cause serious health effects. In addition, EPA has identified health 
concerns for potential incineration products for the PMN substance 
based on analogy to perfluorinated octane sulfonate (PFOS) and 
perfluorinated octanoic acid (PFOA). These incineration products are 
PBT. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day inhalation 
toxicity study in rats with a 60-day holding period (OPPTS 870.3465 
test guideline) would help characterize the human health effects of the 
PMN substance. Special attention should be given to histopathology 
(inflammation and cell proliferation) of the lung tissues and to 
various parameters of the bronchoalveolar lavage fluid (BALF), e.g., 
marker enzyme activities, total protein content, total cell count, cell 
differential, and cell viability. It is not necessary to look at 
internal organs. The Agency has also determined that the following 
tests would help characterize fate and ecotoxicity of the PMN 
substance: A Decomposition Kinetics by Thermogravimeter (ASTM E1641), a 
Compositional Analysis by Thermogravimeter (ASTM E1131), and a 
Laboratory "Burn" test - protocol to be agreed upon by EPA and the 
Company. The purpose of this test is to determine the disposition of 
the material and to identify degradates, especially the presence of 
components that can lead to the formation of perfluofo alkyl carboxylic 
acid after burning or incineration.
CFR citation: 40 CFR 721.9502.

PMN Number P-00-1195
Chemical name: Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-
bis(ethylamino)-2,7- dimethyl-, ethyl sulfate.
CAS number: 26694-69-9.
Basis for action: The PMN substance will be used as a dye for complex 
basic dye pigment manufacture. Based on submitted test data for an 
analog, EPA has identified health concerns for toxic effects to the 
liver and heart. Since significant worker exposure is unlikely when 
used as described in the PMN, EPA has not determined that the proposed 
manufacturing, processing, and use of the substance may present an 
unreasonable risk. EPA has determined, however, that domestic 
manufacture or use of the PMN substance other than as an intermediate 
could result in serious health effects. Also, based on structural 
analogy to cationic dyes, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 2 ppb of the PMN 
substance in surface waters. Since significant environmental exposure 
is not expected when the PMN substance is used as described in the PMN, 
EPA has not determined that the proposed use of the substance may 
present an unreasonable risk. EPA has determined, however, that use of 
the substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(ii) and 
(b)(4)(ii).
Recommended testing: EPA has determined that an acute oral toxicity 
study (40 CFR part 799.9110(d)(1)(i)(A)), a Salmonella typhimurium 
reverse mutation assay (OPPTS 870.5100 test guideline), a 28-day oral 
toxicity study Organization for Economic Cooperation and Development 
(OECD) guideline no. 407 or OPPTS 870.3050 test guideline), and an in 
vivo mammalian cytogenetics test by the intraperitoneal (i.p.) route: 
micronucleus assay (OPPTS 870.5395 test guideline) would help to 
characterize the human health effects of the PMN substance. EPA has 
also determined that a fish acute toxicity study (OPPTS 850.1075 test 
guideline (public draft)), a daphnid acute toxicity study (OPPTS 
850.1010 test guideline (public draft)), and an algal acute toxicity 
study (OPPTS 850.5400 test guideline (public draft)) would help to 
characterize the environmental effects of the PMN substance. The fish 
and daphnid tests should be conducted with flow-through methods and 
measured concentration. The algal test should be conducted with static 
methods and measured concentration. Dilution water hardness < 180 mg/L 
as CaC03.
CFR citation: 40 CFR 721.2465.

PMN Number P-01-0432
Chemical name: (generic) Bis heterocyclic phenylene derivative.
CAS number: Not available.
Basis for action: The PMN substance will be used as a reactive modifier 
for polymeric substances. EPA has identified health concerns for 
neurotoxicity, developmental toxicity, mutagenicity, carcinogenicity, 
lung and liver toxicity, and sensitization based on test data. Since 
significant worker exposure is unlikely because there would not be 
significant inhalation exposure for the use identified in the PMN, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the substance as described in the PMN present an unreasonable risk. 
EPA has determined, however, that an increase in production volume over 
that described in the PMN could result in significant exposure to human 
health. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(ii) and (b)(1)(i)(A).
Recommended testing: EPA has determined that a mouse micronucleus test 
by the i.p. route (OPPTS 870.5395 test guideline) and a 28-day oral 
toxicity in rats OECD guideline number 407 or (OPPTS 870.3050) with a 
Functional Observational Battery (FOB) would help to characterize the 
health effects of the substance. If the above tests indicate a health 
concern, then the following tests may be necessary to qualify the 
potential health effects: a 90-day subchronic oral study in rats (OPPT 
870.3100 test guideline), a prenatal development toxicity study by oral 
route in two species (OPPTS 870.3700 test guideline), a reproduction 
and fertility effects (OPPTS 870.3800 test guideline), and a 
carcinogenicity study (OPPTS 870.4200 test guideline).
CFR citation: 40 CFR 721.5925.

IV. Objectives and Rationale of the Rule

    During review of the PMNs submitted for the chemical substances 
that are subject to this SNUR, EPA concluded that for 3 of the 62 
substances, regulation was warranted under section 5(e) of TSCA, 
pending the development of information sufficient to make reasoned 
evaluations of the health or environmental effects of the substances. 
The basis for such findings is outlined in Unit III. Based on these 
findings, TSCA section 5(e) consent orders requiring the use of 
appropriate exposure controls were negotiated with the PMN submitters; 
the SNUR provisions for these substances designated herein are 
consistent with the provisions of the TSCA section 5(e) consent orders.
    In the other 59 cases for which the proposed uses are not regulated 
under a TSCA section 5(e) consent order, EPA determined that one or 
more of the criteria of concern established at 40 CFR 721.170 were met.
    EPA is issuing this SNUR for specific chemical substances which 
have undergone premanufacture review to ensure that:
    1. EPA will receive notice of any company's intent to manufacture, 
import, or process a listed chemical

[[Page 15077]]

substance for a significant new use before that activity begins.
    2. EPA will have an opportunity to review and evaluate data 
submitted in a SNUR notice before the notice submitter begins 
manufacturing, importing, or processing a listed chemical substance for 
a significant new use.
    3. When necessary, to prevent unreasonable risks, EPA will be able 
to regulate prospective manufacturers, importers, or processors of a 
listed chemical substance before a significant new use of that 
substance occurs.
    4. All manufacturers, importers, and processors of the same 
chemical substance which is subject to a TSCA section 5(e) consent 
order are subject to similar requirements.
    Issuance of a SNUR for a chemical substance does not signify that 
the substance is listed on the TSCA Inventory. Manufacturers, 
importers, and processors are responsible for ensuring that a new 
chemical substance subject to a final SNUR is listed on the TSCA 
Inventory.

V. Direct Final Procedures

    EPA is issuing these SNURs as a direct final rule, as described in 
40 CFR 721.160(c)(3) and 721.170(d)(4). In accordance with 40 CFR 
721.160(c)(3)(ii), this rule will be effective May 27, 2003, unless EPA 
receives a written notice by April 28, 2003 that someone wishes to make 
adverse or critical comments on EPA's action. If EPA receives such a 
notice, EPA will publish a document to withdraw the direct final SNUR 
for the specific substance to which the adverse or critical comments 
apply. EPA will then propose a SNUR for the specific substance 
providing a 30-day comment period.
    This action establishes SNURs for a number of chemical substances. 
Any person who submits a notice of intent to submit adverse or critical 
comments must identify the substance and the new use to which it 
applies. EPA will not withdraw a SNUR for a substance not identified in 
a notice.

VI. Test Data and Other Information

    EPA recognizes that section 5 of TSCA does not require developing 
any particular test data before submission of a SNUN. Persons are 
required only to submit test data in their possession or control and to 
describe any other data known to or reasonably ascertainable by them. 
In cases where a TSCA section 5(e) consent order requires or recommends 
certain testing, Unit III. lists those recommended tests.
    However, EPA has established production limits in the TSCA section 
5(e) consent orders for several of the substances regulated under this 
rule, in view of the lack of data on the potential health and 
environmental risks that may be posed by the significant new uses or 
increased exposure to the substances. These production limits cannot be 
exceeded unless the PMN submitter first submits the results of toxicity 
tests that would permit a reasoned evaluation of the potential risks 
posed by these substances. Under recent consent orders, each PMN 
submitter is required to submit each study at least 14 weeks (earlier 
consent orders required submissions at least 12 weeks) before reaching 
the specified production limit. Listings of the tests specified in the 
TSCA section 5(e) consent orders are included in Unit III. The SNURs 
contain the same production volume limits as the consent orders. 
Exceeding these production limits is defined as a significant new use.
    The recommended studies may not be the only means of addressing the 
potential risks of the substance. However, SNUNs submitted for 
significant new uses without any test data may increase the likelihood 
that EPA will take action under TSCA section 5(e), particularly if 
satisfactory test results have not been obtained from a prior 
submitter. EPA recommends that potential SNUN submitters contact EPA 
early enough so that they will be able to conduct the appropriate 
tests.
    SNUN submitters should be aware that EPA will be better able to 
evaluate SNUNs which provide detailed information on:
    1. Human exposure and environmental release that may result from 
the significant new use of the chemical substances.
    2. Potential benefits of the substances.
    3. Information on risks posed by the substances compared to risks 
posed by potential substitutes.

VII. Procedural Determinations

    EPA is establishing through this rule some significant new uses 
which have been claimed as CBI subject to Agency confidentiality 
regulations at 40 CFR part 2. EPA is required to keep this information 
confidential to protect the CBI of the original PMN submitter. EPA 
promulgated a procedure to deal with the situation where a specific 
significant new use is CBI. This procedure appears in 40 CFR 
721.1725(b)(1) and is similar to that in Sec.  721.11 for situations 
where the chemical identity of the substance subject to a SNUR is CBI. 
This procedure is cross-referenced in each of these SNURs.
    A manufacturer or importer may request EPA to determine whether a 
proposed use would be a significant new use under this rule. Under the 
procedure incorporated from Sec.  721.1725(b)(1), a manufacturer or 
importer must show that it has a bona fide intent to manufacture or 
import the substance and must identify the specific use for which it 
intends to manufacture or import the substance. If EPA concludes that 
the person has shown a bona fide intent to manufacture or import the 
substance, EPA will tell the person whether the use identified in the 
bona fide submission would be a significant new use under the rule. 
Since most of the chemical identities of the substances subject to 
these SNURs are also CBI, manufacturers and processors can combine the 
bona fide submission under the procedure in Sec.  721.1725(b)(1) with 
that under Sec.  721.11 into a single step.
    If a manufacturer or importer is told that the production volume 
identified in the bona fide submission would not be a significant new 
use, i.e. it is below the level that would be a significant new use, 
that person can manufacture or import the substance as long as the 
aggregate amount does not exceed that identified in the bona fide 
submission to EPA. If the person later intends to exceed that volume, a 
new bona fide submission would be necessary to determine whether that 
higher volume would be a significant new use. EPA is considering 
whether to adopt a special procedure for use when CBI production volume 
is designated as a significant new use. Under such a procedure, a 
person showing a bona fide intent to manufacture or import the 
substance, under the procedure described in Sec.  721.11, would 
automatically be informed of the production volume that would be a 
significant new use. Thus, the person would not have to make multiple 
bona fide submissions to EPA for the same substance to remain in 
compliance with the SNUR, as could be the case under the procedures in 
Sec.  721.1725(b)(1).

VIII. Applicability of Rule to Uses Occurring Before Effective Date of 
the Final Rule

    To establish a significant "new" use, EPA must determine that the 
use is not ongoing. The chemical substances subject to this rule have 
recently undergone premanufacture review. TSCA section 5(e) consent 
orders have been issued for 3 substances and notice submitters are 
prohibited by the TSCA section 5(e) consent orders from undertaking 
activities which EPA is designating as significant new uses. In cases 
where EPA has not received an NOC and the substance has not been

[[Page 15078]]

added to the Inventory, no other person may commence such activities 
without first submitting a PMN. For substances for which an NOC has not 
been submitted at this time, EPA has concluded that the uses are not 
ongoing. However, EPA recognizes in cases when chemical substances 
identified in this SNUR are added to the Inventory prior to the 
effective date of the rule, the substances may be manufactured, 
imported, or processed by other persons for a significant new use as 
defined in this rule before the effective date of the rule. However, 41 
of the 62 substances contained in this rule have CBI chemical 
identities, and since EPA has received a limited number of post-PMN 
bona fide submissions, the Agency believes that it is highly unlikely 
that any of the significant new uses described in the following 
regulatory text are ongoing.
    As discussed in the Federal Register of April 24, 1990, EPA has 
decided that the intent of section 5(a)(1)(B) of TSCA is best served by 
designating a use as a significant new use as of the date of 
publication rather than as of the effective date of the rule. Thus, 
persons who begin commercial manufacture, import, or processing of the 
substances regulated through this SNUR will have to cease any such 
activity before the effective date of this rule. To resume their 
activities, these persons would have to comply with all applicable SNUR 
notice requirements and wait until the notice review period, including 
all extensions, expires.
    EPA has promulgated provisions to allow persons to comply with this 
SNUR before the effective date. If a person were to meet the conditions 
of advance compliance under Sec.  721.45(h), the person would be 
considered to have met the requirements of the final SNUR for those 
activities. If persons who begin commercial manufacture, import, or 
processing of the substance between publication and the effective date 
of the SNUR do not meet the conditions of advance compliance, they must 
cease that activity before the effective date of the rule. To resume 
their activities, these persons would have to comply with all 
applicable SNUR notice requirements and wait until the notice review 
period, including all extensions, expires.

IX. Economic Analysis

    EPA has evaluated the potential costs of establishing SNUN 
requirements for potential manufacturers, importers, and processors of 
the chemical substance subject to this rule. EPA's complete economic 
analysis is available in the official public docket.

X. Statutory and Executive Order Reviews

    Under Executive Order 12866, entitled Regulatory Planning and 
Review (58 FR 51735, October 4, 1993), the Office of Management and 
Budget (OMB) has determined that proposed or final SNURs are not a 
"significant regulatory action" subject to review by OMB, because 
they do not meet the criteria in section 3(f) of the Executive Order.
    According to the Paperwork Reduction Act (PRA), 44 U.S.C. 3501 et 
seq., an Agency may not conduct or sponsor, and a person is not 
required to respond to a collection of information that requires OMB 
approval under the PRA, unless it has been approved by OMB and displays 
a currently valid OMB control number. The OMB control numbers for EPA's 
regulations in title 40 of the CFR, after appearing in the Federal 
Register, are listed in 40 CFR part 9, and included on the related 
collection instrument or form, if applicable.
    The information collection requirements related to this action have 
already been approved by OMB pursuant to the PRA under OMB control 
number 2070-0012 (EPA ICR No. 574). This action does not impose any 
burden requiring additional OMB approval. If an entity were to submit a 
SNUN to the Agency, the annual burden is estimated to average between 
30 and 170 hours per response. This burden estimate includes the time 
needed to review instructions, search existing data sources, gather and 
maintain the data needed, and complete, review, and submit the required 
SNUN.
    Send any comments about the accuracy of the burden estimate, and 
any suggested methods for minimizing respondent burden, including 
through the use of automated collection techniques, to the Director, 
Collection Strategies Division, Office of Environmental Information 
(2822T), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., 
Washington, DC 20460-0001. Please remember to include the OMB control 
number in any correspondence, but do not submit any completed forms to 
this address.
    Pursuant to section 605(b) of the Regulatory Flexibility Act (RFA) 
(5 U.S.C. 601 et seq.), the Agency hereby certifies that promulgation 
of this SNUR will not have a significant adverse economic impact on a 
substantial number of small entities. The rationale supporting this 
conclusion is as follows. A SNUR applies to any person (including small 
or large entities) who intends to engage in any activity described in 
the rule as a "significant new use." By definition of the word 
"new," and based on all information currently available to EPA, it 
appears that no small or large entities presently engage in such 
activity. Since a SNUR only requires that any person who intends to 
engage in such activity in the future must first notify EPA by 
submitting a SNUN, no economic impact will even occur until someone 
decides to engage in those activities. Although some small entities may 
decide to conduct such activities in the future, EPA cannot presently 
determine how many, if any, there may be. However, EPA's experience to 
date is that, in response to the promulgation of over 900 SNURs, the 
Agency has received fewer than 25 SNUNs. Of those SNUNs submitted, none 
appear to be from small entities in response to any SNUR. In addition, 
the estimated reporting cost for submission of a SNUN (see Unit IX.), 
are minimal regardless of the size of the firm. Therefore, EPA believes 
that the potential economic impact of complying with this SNUR are not 
expected to be significant or adversely impact a substantial number of 
small entities. In a SNUR that published on June 2, 1997 (62 FR 29684) 
(FRL-5597-1), the Agency presented it's general determination that 
proposed and final SNURs are not expected to have a significant 
economic impact on a substantial number of small entities, which was 
provided to the Chief Counsel for Advocacy of the Small Business 
Administration.
    Based on EPA's experience with proposing and finalizing SNURs, 
State, local, and tribal governments have not been impacted by these 
rulemakings, and EPA does not have any reasons to believe that any 
State, local, or tribal government will be impacted by this rulemaking. 
As such, EPA has determined that this regulatory action does not impose 
any enforceable duty, contain any unfunded mandate, or otherwise have 
any affect on small governments subject to the requirements of sections 
202, 203, 204, or 205 of the Unfunded Mandates Reform Act of 1995 
(UMRA) (Public Law 104-4).
    This action will not have a substantial direct effect on States, on 
the relationship between the national government and the States, or on 
the distribution of power and responsibilities among the various levels 
of government, as specified in Executive Order 13132, entitled 
Federalism (64 FR 43255, August 10, 1999).
    This rule does not have tribal implications because it is not 
expected to have substantial direct effects on

[[Page 15079]]

Indian Tribes. This does not significantly or uniquely affect the 
communities of Indian tribal governments, nor does it involve or impose 
any requirements that affect Indian Tribes. Accordingly, the 
requirements of Executive Order 13175, entitled Consultation and 
Coordination with Indian Tribal Governments (65 FR 67249, November 6, 
2000), do not apply to this rule.
    This action is not subject to Executive Order 13045, entitled 
Protection of Children from Environmental Health Risks and Safety Risks 
(62 FR 19885, April 23, 1997), because this is not an economically 
significant regulatory action as defined by Executive Order 12866, and 
this action does not address environmental health or safety risks 
disproportionately affecting children.
    This rule is not subject to Executive Order 13211, entitled Actions 
Concerning Regulations That Significantly Affect Energy Supply, 
Distribution, or Use (66 FR 28355, May 22, 2001), because this action 
is not expected to affect energy supply, distribution, or use.
    In addition, since this action does not involve any technical 
standards, section 12(d) of the National Technology Transfer and 
Advancement Act of 1995 (NTTAA), Public Law 104-113, section 12(d) (15 
U.S.C. 272 note), does not apply to this action.
    This action does not entail special considerations of environmental 
justice related issues as delineated by Executive Order 12898, entitled 
Federal Actions to Address Environmental Justice in Minority 
Populations and Low-Income Populations (59 FR 7629, February 16, 1994).
    EPA has complied with Executive Order 12630, entitled Governmental 
Actions and Interference with Constitutionally Protected Property 
Rights (53 FR 8859, March 15, 1988), by examining the takings 
implications of this rule in accordance with the "Attorney General's 
Supplemental Guidelines for the Evaluation of Risk and Avoidance of 
Unanticipated Takings" issued under the Executive Order.
    In issuing this rule, EPA has taken the necessary steps to 
eliminate drafting errors and ambiguity, minimize potential litigation, 
and provide a clear legal standard for affected conduct, as required by 
section 3 of Executive Order 12988, entitled Civil Justice Reform (61 
FR 4729, February 7, 1996).

XI. Congressional Review Act

    The Congressional Review Act, 5 U.S.C. 801 et seq., as added by the 
Small Business Regulatory Enforcement Fairness Act of 1996, generally 
provides that before a final rule may take effect, the Agency 
promulgating it must submit a final rule report, which includes a copy 
of the final rule, to each House of the Congress and to the Comptroller 
General of the United States. EPA will submit a report containing this 
final rule and other required information to the U.S. Senate, the U.S. 
House of Representatives, and the Comptroller General of the United 
States prior to publication of the final rule in the Federal Register. 
This final rule is not a "major rule" as defined by 5 U.S.C. 804(2).

List of Subjects in 40 CFR Part 721

    Environmental protection, Chemicals, Hazardous substances, 
Reporting and recordkeeping requirements.


    Dated: March 17, 2003.
Charles M. Auer,
Director, Office of Pollution Prevention and Toxics.

0
Therefore, 40 CFR part 721 is amended as follows:

PART 721--[AMENDED]

0
1. The authority citation for part 721 continues to read as follows:

    Authority: 15 U.S.C. 2604, 2607, and 2625(c).

0
2. By adding new Sec.  721.321 to subpart E to read as follows:


Sec.  721.321  Substituted acrylamides and acrylic acid copolymer 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted acrylamides and acrylic acid copolymer (PMN P-00-0490) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (f), (v)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
3. By adding new Sec.  721.338 to subpart E to read as follows:


Sec.  721.338  Salt of an acrylate copolymer (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as salt 
of an acrylate copolymer (PMNs P-00-0333 and P-00-0334) are subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(2), (w)(2), and (x)(2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
4. By adding new Sec.  721.463 to subpart E to read as follows:


Sec.  721.463  Acrylate of polymer based on isophorone diisocyanate 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
acrylate of polymer based on isophorone diisocyanate (PMN P-00-0626) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), (c)(4) (N=3 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
5. By adding new Sec.  721.465 to subpart E to read as follows:


Sec.  721.465  Alkoxylated alkylpolyol acrylates, adduct with 
alkylamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting.

[[Page 15080]]

(1) The chemical substances identified generically as alkoxylated 
alkylpolyol acrylates, adduct with alkylamine (PMNs P-98-0082, P-98-
0083, and P-98-0084 are subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
6. By adding new Sec.  721.522 to subpart E to read as follows:


Sec.  721.522  Oxirane, methyl-, polymer with oxirane, mono(3,5,5,-
trimethylhexyl) ether.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxirane, methyl-, 
polymer with oxirane, mono(3,5,5,-trimethylhexyl) ether (PMN P-99-0669; 
CAS No. 204336-40-3) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
7. By adding new Sec.  721.525 to subpart E to read as follows:


Sec.  721.525  1-propanol, 3-propoxy-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1-propanol, 3-
propoxy- (PMN P-00-0827; CAS No. 4161-22-2) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63 (a)(2)(i) and (a)(3).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o) and (j).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (d), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
8. By adding new Sec.  721.532 to subpart E to read as follows:


Sec.  721.532  Substituted hydroxyalkane acetate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted hydroxyalkane acetate (PMN P-00-0618) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
9. By adding new Sec.  721.533 to subpart E to read as follows:


Sec.  721.533  Propane, 1,1,1,3,3-pentachloro-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as propane, 1,1,1,3,3-
pentachloro- (PMN P-99-1327; CAS No. 23153-23-3) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
10. By adding new Sec.  721.638 to subpart E to read as follows:


Sec.  721.638  Silyl amine, potassium salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as silyl 
amine, potassium salt (PMN P-00-1086) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
11. By adding new Sec.  721.648 to subpart E to read as follows:


Sec.  721.648  Alkyl dialkylamino phenylsulfonyl alkenoate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkyl 
dialkylamino phenylsulfonyl alkenoate (PMN P-00-0816) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:

[[Page 15081]]

    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
12. By adding new Sec.  721.843 to subpart E to read as follows:


Sec.  721.843  Substituted phenylazophenylazo phenol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted phenylazophenylazo, phenol (PMN P-00-0420) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
13. By adding new Sec.  721.910 to subpart E to read as follows:


Sec.  721.910  Propanetriol polyalkylenepolyolamine aryl aldimine 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
propanetriol polyalkylenepolyolamine aryl aldimine (PMN P-99-0873) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
14. By adding new Sec.  721.984 to subpart E to read as follows:


Sec.  721.984  Amino-hydroxy sulfonaphthylazo-disubstituted phenyl azo 
benzene carboxylate salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as amino-
hydroxy sulfonaphthylazo-disubstituted phenyl azo benzene carboxylate 
salt (PMN P-00-0351) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(2), (w)(2), (x)(2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
15. By adding new Sec.  721.990 to subpart E to read as follows:


Sec.  721.990  1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 
1,4 - butanediol, cyclized.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,4-
benzedicarboxylic acid, dimethyl ester, polymer with 1,4 - butanediol, 
cyclized (PMN P-00-0789; CAS No. 263244-54-8) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
16. By adding new Sec.  721.1767 to subpart E to read as follows:


Sec.  721.1767  Substituted 6,6'-(1-methylethylidene)bis[3,4-dihydro-3-
phenyl-1,3-benzoxazine] (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted 6,6'-(1-methylethylidene)bis[3,4-dihydro-3-phenyl-1,3-
benzoxazine] (PMN P-00-0993) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
17. By adding new Sec.  721.1852 to subpart E to read as follows:


Sec.  721.1852  Di-alkyl borane (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as di-
alkyl borane (PMN P-00-1087) is subject to reporting under this section 
for the significant new use described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=200 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.

[[Page 15082]]

    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
18. By adding new Sec.  721.1878 to subpart E to read as follows:


Sec.  721.1878  Alkali metal alkyl borohydride (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkali 
metal alkyl borohydride (PMN P-00-1089) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
19. By adding new Sec.  721.1880 to subpart E to read as follows:


Sec.  721.1880  Borate(1-), tris(acetato-.kappa.O)hydro-, sodium, (T-
4)-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as borate(1-), 
tris(acetato-.kappa.O)hydro-, sodium, (T-4)- (PMN P-00-0922; CAS No. 
56553-60-7) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=300 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
20. By adding new Sec.  721.2093 to subpart E to read as follows:


Sec.  721.2093  Alkenyl carboxylate, metal salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkenyl 
carboxylate, metal salt (PMN P-99-0848) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (an emulsifier for metalworking fluids) 
and (q).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
21. By adding new Sec.  721.2155 to subpart E to read as follows:


Sec.  721.2155  Alkoxyamino-alkyl-coumarin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkoxyamino-alkyl-coumarin. (PMN P-00-0108) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
22. By adding new Sec.  721.2465 to subpart E to read as follows:


Sec.  721.2465  Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-
bis(ethylamino)-2,7-dimethyl-, ethyl sulfate.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as xanthylium, 9-(2-
(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, ethyl 
sulfate (PMN P-00-1195; CAS No. 26694-69-9) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f) and (j) (a basic dye for complex basic 
dye pigment manufacture).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
23. By adding new Sec.  721.2577 to subpart E to read as follows:


Sec.  721.2577  Copper complex of (substituted sulfonaphthyl azo 
substituted phenyl) disulfonaphthyl azo, amine salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as copper 
complex of (substituted sulfonaphthyl azo substituted phenyl) 
disulfonaphthyl azo, amine salt (PMNs P-00-0364 and P-00-0365) are 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

[[Page 15083]]


0
24. By adding new Sec.  721.2582 to subpart E to read as follows:


Sec.  721.2582  Reaction product of alkylene diamine, MDl, substituted 
carbomonocyclic amine and alkylamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
reaction product of alkylene diamine, MDl, substituted carbomonocyclic 
amine and alkylamine (PMN P-98-1262) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
25. By adding new Sec.  721.2584 to subpart E to read as follows:


Sec.  721.2584  Dodecanoic acid, 12-amino-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as dodecanoic acid, 
12-amino- (PMN P-98-0823; CAS No. 693-57-2) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63 (a)(4), (a)(5)(iii), (a)(5)(iv), (a)(5)(v), (a)(5)(vi), 
(a)(5)(vii), (a)(6)(i), (b) (concentration set at 0.1 percent), and 
(g). As an alternative to the respiratory requirements listed here, a 
manufacturer, importer, or processor may choose to follow the NCEL 
provision listed in the 5(e) consent order for this substance. The NCEL 
is 1.0 mg/m\3\ as an 8-hour time-weighted average verified by actual 
monitoring data.
    (ii) Hazard communication program. Requirements as specified in 
Sec.  721.72 (a), (b), (c), (d), (e), (f), (g)(1)(ii), (g)(1)(vii), 
(g)(2)(ii), and (g)(2)(iv).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (g), (r) (6,000,000 kg.), and a 
carcinogenicity study (OPPTS 870.4200). A person may not manufacture or 
import the substance beyond the aggregate production volume limit, 
unless that person conducts this study on the substance and submits all 
final reports and underlying data in accordance with the procedures and 
criteria specified in paragraphs (a)(2)(iii)(A), (a)(2)(iii)(B), 
(a)(2)(iii)(C), and (a)(2)(iii)(D) of this section.
    (A) Each study required to be performed pursuant to this section 
must be scientifically valid. Scientifically valid means that the study 
was conducted according to:
    (1) The test guidelines specified in paragraph (a)(2)(iii) of this 
section.
    (2) An EPA-approved protocol.
    (3) TSCA Good Laboratory Practice Standards at 40 CFR part 792.
    (4) Using methodologies generally accepted at the time the study is 
initiated.
    (5) Any deviation from these requirements must be approved in 
writing by EPA.
    (B) Before starting to conduct any of the studies in paragraph 
(a)(2)(iii) of this section, the person must obtain approval of test 
protocols from EPA by submitting written protocols. EPA will respond to 
the person within 4 weeks of receiving the written protocols. Published 
test guidelines specified in paragraph (a)(2)(iii) of this section 
(e.g., 40 CFR part 797 or part 798) provide general guidance for 
development of test protocols, but are not themselves acceptable 
protocols.
    (C) The person shall:
    (1) Conduct each study in good faith with due care.
    (2) Promptly furnish to EPA the results of any interim phase of 
each study.
    (3) Submit, in triplicate (with an additional sanitized copy, if 
confidential business information is involved), the final report of 
each study and all underlying data ("the report and data") to EPA no 
later than 14 weeks prior to exceeding the applicable production volume 
limit. The final report shall contain the contents specified in 40 CFR 
792.185.
    (D)(1) Except as described in paragraph (a)(2)(iii)(D)(2) of this 
section, if, within 6 weeks of EPA's receipt of a test report and data, 
the person receives written notice that EPA finds that the data 
generated by a study are scientifically invalid, the person is 
prohibited from further manufacture and import of the PMN substance 
beyond the applicable production volume limit.
    (2) The person may continue to manufacture and import the PMN 
substance beyond the applicable production limit only if so notified, 
in writing, by EPA in response to the person's compliance with either 
of the following paragraphs (a)(2)(iii)(D)(2)(i) or 
(a)(2)(iii)(D)(2)(ii) of this section.
    (i) The person may reconduct the study. If there is sufficient time 
to reconduct the study and submit the report and data to EPA at least 
14 weeks before exceeding the production limit as required by paragraph 
(a)(2)(iii)(C)(3) of this section, the person shall comply with 
paragraph (a)(2)(iii)(C)(3) of this section. If there is insufficient 
time for the person to comply with paragraph (a)(2)(iii)(C)(3) of this 
section, the person may exceed the production limit and shall submit 
the report and data in triplicate to EPA within a reasonable period of 
time, all as specified by EPA in the notice described in paragraph 
(a)(2)(iii)(D)(1) of this section. EPA will respond to the person in 
writing, within 6 weeks of receiving the person's report and data.
    (ii) The person may, within 4 weeks of receiving from EPA the 
notice described in paragraph (a)(2)(iii)(D)(1) of this section, submit 
to EPA a written report refuting EPA's finding. EPA will respond to the 
person in writing, within 4 weeks of receiving the person's report.
    (E) The person is not required to conduct a study specified in 
paragraph (a)(2)(iii) of this section if notified in writing by EPA 
that it is unnecessary to conduct that study.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (d), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
26. By adding new Sec.  721.2673 to subpart E to read as follows:


Sec.  721.2673  Aromatic epoxide resin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
aromatic epoxide resin (PMN P-99-1399) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(y)(1).
    (ii) [Reserved]

[[Page 15084]]

    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
27. By adding new Sec.  721.3805 to subpart E to read as follows:


Sec.  721.3805  Formaldehyde, reaction products with 1,3-
benzenedimethanamine and bisphenol A.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as formaldehyde, 
reaction products with 1,3-benzenedimethanamine and bisphenol A (PMN P-
00-0738; CAS No. 259871-68-6) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
28. By adding new Sec.  721.3807 to subpart E to read as follows:


Sec.  721.3807  Formaldehyde, polymer with phenol and 1,2,3-
propanetriol, methylated.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as formaldehyde, 
polymer with phenol and 1,2,3-propanetriol, methylated (PMN P-99-0044; 
CAS No. 209810-57-1) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=3 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
29. By adding new Sec.  721.3812 to subpart E to read as follows:


Sec.  721.3812  Substituted phenols and formaldehyde polymer, alkylated 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted phenols and formaldehyde polymer, alkylated (PMN P-00-0542) 
is subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (a resin for can and tube coatings).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
30. By adding new Sec.  721.3818 to subpart E to read as follows:


Sec.  721.3818  Furan, octafluorotetrahydro-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as furan, 
octafluorotetrahydro- (PMN P-99-0965; CAS No. 773-14-8) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (a heat transfer agent).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
31. By adding new Sec.  721.3848 to subpart E to read as follows:


Sec.  721.3848  Glycine, N-(carboxymethyl)-N-dodecyl-, monosodium salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as glycine, N-
(carboxymethyl)-N-dodecyl-, monosodium salt (PMN P-00-469; CAS No. 
141321-68-8) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), (c)(4) (N=30 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
32. By adding new Sec.  721.4136 to subpart E to read as follows:


Sec.  721.4136  Alkyl heteropolycyclic-aniline (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkyl 
heteropolycyclic-aniline (PMN P-00-0067) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=1 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
33. By adding new Sec.  721.4486 to subpart E to read as follows:

[[Page 15085]]

Sec.  721.4486  Propanoic acid, 2-methyl-, (1R,2R,4R)-1,7,7-
trimethylbicyclo[2.2.1]hept-2-yl ester, rel-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified as propanoic acid, 2-
methyl-, (1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl ester, rel- 
(PMNs P-98-0497 and P-98-0509; CAS No. 85586-67-0) are subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(p) (15,000 kg/yr).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
34. By adding new Sec.  721.4575 to subpart E to read as follows:


Sec.  721.4575  L-aspartic acid, N,N'- [(1E) - 1,2 - ethenediylbis[(3-
sulfo-4, 1-phenylene)imino [6-(phenylamino)-1,3,5-triazine- 4,2- 
diyl]]]bis-, hexasodium salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as l-aspartic acid, 
N,N'- [(1E) - 1,2 - ethenediylbis[(3-sulfo-4, 1-phenylene) imino[6-
(phenylamino)-1,3,5-triazine-4,2-diyl]]]bis-, hexasodium salt (PMN P-
99-1167; CAS No. 205764-98-3) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), (x)(1), and (f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
35. By adding new Sec.  721.4792 to subpart E to read as follows:


Sec.  721.4792  2-propenoic acid, 2-methyl-, C11-14-isoalkyl 
esters, C13-rich.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
2-methyl-, C11-14-isoalkyl esters, C13-rich (PMN 
P-99-1189; CAS No. 85736-97-6) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (a monomer for casting automotive parts 
adhesives or impregnation fluid).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(c)(4) (N=1 ppb).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
36. By adding new Sec.  721.5260 to subpart E to read as follows:


Sec.  721.5260  1,3,6-Naphthalenetrisulfonic acid, 7-[[2-
[(aminocarbonyl)amino]-4-[[4-[[2-[2-
(ethenylsulfonyl)ethoxy]ethyl]amino]-6-fluoro-1,3,5-triazin-2-
yl]amino]phenyl]azo], trisodium salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,3,6-
Naphthalenetrisulfonic acid, 7-[[2-[(aminocarbonyl)amino]-4-[[4-[[2-[2-
(ethenylsulfonyl)ethoxy]ethyl]amino]-6-fluoro-1,3,5-triazin-2-
yl]amino]phenyl]azo], trisodium salt (PMN P-00-0806; CAS No. 106359-91-
5) is subject to reporting under this section for the significant new 
use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
37. By adding new Sec.  721.5262 to subpart E to read as follows:


Sec.  721.5262  2,7-Naphthalenedisulfonic acid, 5-[[4-chloro-6-
[substituted] amino]-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(1-sulfo-2-
naphthalenyl)azo]-, trisodium salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 2,7-
Naphthalenedisulfonic acid, 5-[[4-chloro-6-[substituted] amino]-1,3,5-
triazin-2-yl]amino]-4-hydroxy-3-[(1-sulfo-2-naphthalenyl)azo]-, 
trisodium salt (PMN P-00-0803) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
38. By adding new Sec.  721.5283 to subpart E to read as follows:


Sec.  721.5283  Cobaltate (5-), bis[4-[[6-[(4-amino-6-chloro-1,3,5-
triazin-2-yl)amio]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-3-hydroxy-7-
nitro-1-naphthalenesulfonato(4-)]-, pentasodium.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as cobaltate (5-), 
bis[4-[[6-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amio]-1-hydroxy-3-
sulfo-2-naphthalenyl]azo]-3-hydroxy-7-nitro-1-naphthalenesulfonato(4-
)]-, pentasodium (PMN P-99-0990; CAS No. 91144-26-2) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63 (a)(4), (a)(5)(ii), (a)(5)(xii), and (a)(5)(xiii).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as

[[Page 15086]]

specified in Sec.  721.80(j) (a spray applied automotive coating).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (d), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
39. By adding new Sec.  721.5286 to subpart E to read as follows:


Sec.  721.5286  Benzenediazonium, 
[[[[(substituted)azo]phenyl]sulfonyl]amino]-, coupled with aminophenol, 
diazotized aminobenzoic acid, diazotized (substituted) benzenesulfonic 
acid and naphthalenol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
benzenediazonium, [[[[(substituted) azo]phenyl]sulfonyl]amino]-, 
coupled with aminophenol, diazotized aminobenzoic acid, diazotized 
(substituted) benzenesulfonic acid and naphthalenol (PMN P-00-0045) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
40. By adding new Sec.  721.5452 to subpart E to read as follows:


Sec.  721.5452  Alkali metal salt of halogenated organoborate 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as alkali 
metal salt of halogenated organoborate (PMN P-00-0638) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
41. By adding new Sec.  721.5454 to subpart E to read as follows:


Sec.  721.5454  Methylium, tripohenyl-, tetrakis(pentafluorophenyl) 
borate (1-).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified as methylium, 
tripohenyl-, tetrakis(pentafluorophenyl) borate (1-) (PMN P-00-0637; 
CAS No. 136040-19-2) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
42. By adding new Sec.  721.5590 to subpart E to read as follows:


Sec.  721.5590  Oxirane, [[[(1R,2S,5R)-5-methyl-2-(1-
methylethyl)cyclohexyl]oxy]methyl]-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxirane, 
[[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]methyl]- (PMN P-
00-0330; CAS No. 249297-16-3) is subject to reporting under this 
section for the significant new use described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g).
    (ii) Release to water. Requirements as specified Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
43. By adding new Sec.  721.5925 to subpart E to read as follows:


Sec.  721.5925  Bis heterocyclic phenylene derivative (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as bis 
heterocyclic phenylene derivative (PMN P-01-0432) is subject to 
reporting under this section for the significant new use described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(p) (20,000 kg/yr).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
44. By adding new Sec.  721.6005 to subpart E to read as follows:


Sec.  721.6005  Rare earth phosphate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as rare 
earth phophate (PMNs P-99-1191 and P-99-1192) are subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125

[[Page 15087]]

(a), (b), (c), and (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
45. By adding new Sec.  721.6178 to subpart E to read as follows:


Sec.  721.6178  Alkylaminated polyolefin (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkylaminated polyolefin (PMN P-99-1287) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
46. By adding new Sec.  721.6181 to subpart E to read as follows:


Sec.  721.6181  Fatty acid, reaction product with substituted oxirane, 
formaldehyde-phenol polymer glycidyl ether, substituted proplyamine and 
polyethylenepolyamines (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acid, reaction product with substituted oxirane, formaldehyde-phenol 
polymer glycidyl ether, substituted proplyamine and 
polyethylenepolyamines (PMN P-98-1125) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=10ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
47. By adding new Sec.  721.6183 to subpart E to read as follows:


Sec.  721.6183  Amides, from ammonium hydroxide - maleic anhydride 
polymer and hydrogenated tallow alkyl amines, sodium salts, compds. 
with ethanolamine.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as amides, from 
ammonium hydroxide - maleic anhydride polymer and hydrogenated tallow 
alkyl amines, sodium salts, compds. with ethanolamine (PMN P-00-0691; 
CAS No. 208408-03-1) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), and (c)(4) (N=80 ppb).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
48. By adding new Sec.  721.6205 to subpart E to read as follows:


Sec.  721.6205  Hexamethylenediamine adduct of substituted 
piperidinyloxy (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hexamethylenediamine adduct of substituted piperidinyloxy (PMN P-99-
0510) is subject to reporting under this section for the significant 
new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63 (a)(i), (a)(2)(i), (a)(3), (a)(4), (a)(5)(i), (a)(5)(ii), 
(a)(5)(iii), (a)(5)(iv), (a)(5)(v), (a)(5)(vi), (a)(5)(vii), 
(a)(5)(viii), (a)(5)(ix), (a)(5)(x), (a)(5)(xi), (a)(5)(xii), 
(a)(5)(xiii) (a)(5)(xiv), (a)(5)(xv), (a)(6)(i), (a)(6)(ii), 
(a)(6)(iii), (a)(6)(iv), (a)(6)(v), and (a)(6)(vi), (b) (concentration 
set at 1.0 percent), and (c). The imperviousness of each item pursuant 
to paragraph (a)(2)(i) must be demonstrated by actual testing under 
paragraph (a)(3) and not by manufacturer specifications. Permeation 
testing shall be conducted according to the American Society for 
Testing and Materials (ASTM) F739 "Standard Test Method for Resistance 
of Protective Clothing Materials to Permeation by Liquids or Gases" or 
its equivalent. Results shall be recorded as a cumulative permeation 
rate as a function of time, and shall be documented in accordance with 
ASTM F739 using the format specified in ASTM 1194-89 "Guide for 
Documenting the Results of Chemical Permeation Testing on Protective 
Clothing Materials" or its equivalent. Gloves may not be used for a 
time period longer than they are actually tested and must be replaced 
at the end of each work shift. The manufacturer, importer, or processor 
must submit all test data to the Agency and must receive written Agency 
approval for each type of glove tested prior to use of such gloves. The 
following gloves have been tested in accordance with the ASTM F739 
method and found to satisfy the requirements for use by EPA: Latex (at 
least 14 mils thick), Nitrile (at least 16 mils thick), and 
Silvershield (at least 3 mils thick). As an alternative to the 
respiratory requirements listed here, a manufacturer, importer, or 
processor may choose to follow the NCEL provisions listed in the TSCA 
section 5(e) consent order for this substance. The NCEL is 0.2 ug/m\3\ 
as an 8-hour time weighted average verified by actual monitoring data.
    (ii) Hazard communication program. Requirements as specified in 
Sec.  721.72 (a), (b), (c), (d), (e) (concentration set at 0.1 
percent), (f), (g)(1)(i), (g)(1)(ii), (g)(1)(iv), (g)(1)(vi), 
(g)(1)(viii), (g)(2)(i), (g)(2)(ii), (g)(2)(iv), (g)(2)(v), and (g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (d), (e), (f), (g), (h), and (i) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

[[Page 15088]]


0
49. By adding new Sec.  721.8085 to subpart E to read as follows:


Sec.  721.8085  Reaction product of substituted aromatic diol, 
formaldehyde and alkanolamine, propoxylated (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
reaction product of substituted aromatic diol, formaldehyde and 
alkanolamine, propoxylated (PMN P-00-0202) is subject to reporting 
under this section for the significant new use described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
50. By adding new Sec.  721.8658 to subpart E to read as follows:


Sec.  721.8658  Modified polymer of vinyl acetate and quaternary 
ammonium compound (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
modified polymer of vinyl acetate and quaternary ammonium compound (PMN 
P-99-0874) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
51. By adding new Sec.  721.8920 to subpart E to read as follows:


Sec.  721.8920  4,6-Disubstituted pyrimidine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 4,6-
disubstituted pyrimidine (PMN P-99-1366) is subject to reporting under 
this section for the significant new use described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
52. By adding new Sec.  721.9502 to subpart E to read as follows:


Sec.  721.9502  Siloxanes and silicones, aminoalkyl, fluorooctyl, 
hydroxy-terminated salt (generic).

    (a) Chemical substance and significant new uses subject to 

reporting. (1) The chemical substance identified generically as 
siloxanes and silicones, aminoalkyl, fluorooctyl, hydroxy-terminated 
salt (PMN P-00-1132) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (graffiti systems) and (y)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to this section.

0
53. By adding new Sec.  721.9504 to subpart E to read as follows:


Sec.  721.9504  Silane, triethoxy (3,3,4,4,5,5, 6,6,7,7,8,8,8-
tridecafluorooctyl)-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as silane, triethoxy 
(3,3,4,4,5, 5,6,6,7,7,8,8,8-tridecafluorooctyl)- (PMN P-99-1346; CAS 
No. 51851-37-7) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63 (a)(4), (a)(5)(ii),( (a)(5)(xii), and (a)(5)(xiii).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a),(b), (c), (d), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
54. By adding new Sec.  721.9520 to subpart E to read as follows:


Sec.  721.9520  Methylated-para-rosaniline salt of a trisulfonated 
triarylmethane dye (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
methylated-para-rosaniline salt of a trisulfonated triarylmethane dye 
(PMN P-00-0559) is subject to reporting under this section for the 
significant new use described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) Release to water. Requirements as specified in Sec.  721.90 
(a)(4), (b)(4), (c)(4) (N=2 ppb).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
55. By adding new Sec.  721.9538 to subpart E to read as follows:

[[Page 15089]]

Sec.  721.9538  Lithium salt of sulfophenyl azo phenyl azo 
disulfostilbene (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as lithium 
salt of sulfophenyl azo phenyl azo disulfostilbene (PMN P-00-0698) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(2), (w)(2), (x)(2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
56. By adding new Sec.  721.9597 to subpart E to read as follows:


Sec.  721.9597  Salt of a substituted sulfonated aryl azo compound 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as salt of 
a substituted sulfonated aryl azo compound (PMN P-00-0094) is subject 
to reporting under this section for the significant new use described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
57. By adding new Sec.  721.9952 to subpart E to read as follows:


Sec.  721.9952  Alkoxylated aliphatic diisocyanate allyl ether 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkoxylated aliphatic diisocyanate allyl ether (PMN P-00-0353) is 
subject to reporting under this section for the significant new use 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

[FR Doc. 03-7373 Filed 3-27-03; 8:45 am]

BILLING CODE 6560-50-S
      

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