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4-Vinylcyclohexene (VCH) Test Results


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CAS No. 100-40-3

ITC Recommendation/Designation - 25th and 27th Reports
54 FR 51114; December 12, 1989/Recommmended
56 FR 9534; March 6, 1991/Designated

Consent Agreement (CO)
56 FR 47912; September 23, 1991

Project Manager: John Harris, Mary Lou Hewlett

Branch Chief: Frank Kover

Status: Closed. All required tests have been completed. Test results have been forwarded to the Risk Assessment Division for review and disposition.

Announced Receipt of Test Data

CMA submitted a volatilization from water study (57 FR 37541; August 19, 1992).

CMA submitted an initial submission: letter concerning results on inhalation exposure to 4-VCH in rats and mice (bone marrow micronucleus tests) (57 FR 53899; November 13, 1992).

CMA’s Butadiene Panel submitted test data describing the partition coefficient of 4VCH and metabolites. The submission was received by EPA on March 22, 1993 (58 FR 21302; April 20, 1993).

Test data for 4-VCH were submitted by CMA’s Butadiene Panel pursuant to a Consent Order that was received by EPA on September 20 and 22, 1993. The submissions describe a “rat and mouse bone marrow micronucleus assay following subchronic inhalation exposure” and an “in vitro metabolism of 4VCH and metabolites” (58 FR 57602; October 26, 1993).

Test data for 4-VCH were submitted by CMA’s Butadiene Panel pursuant to a Consent Order that was received by EPA on February 25, 1994. The submission describe a subchronic toxicity study by inhalation in rats and mice (59 FR 17101; April 11, 1994).

Results of Testing Table



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