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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received July 2002

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0702-13853A (PDF) Quinazolinone *2 Confidential   Confidential Results of an acute oral toxicity study in rats with a mixture containing the chemical
8EHQ-0702-15165A (PDF) Chemical Confidential   Confidential Results of mouse micronucleus study and results of an acute oral toxicity study in rats
8EHQ-0702-15166A (PDF) Hexabromocyclododecane 25637-99-4 N Bromine Science and Environmental Forum Results of an environmental monitoring and bioaccumulation study
8EHQ-0702-15167A (PDF) 2-(2-Amino-ethylamino) ethanol 111-41-1 Y Ethyleneamines Product Stewardship Discussion Group Preliminary results of an oral reproductive/developmental toxicity screening test in rats
8EHQ-0702-15168A (PDF) Magenta ink Confidential   Confidential Results of two dermal sensitization studies in mice
8EHQ-0702-15169A (PDF) Yellow ink Confidential   Confidential Results of a dermal sensitization study in mice
8EHQ-0702-15170A (PDF) Nitrogen-containing heterocycle *2 Confidential   BASF Corporation Results of a mouse micronucleus screening study
8EHQ-0702-15171A (PDF) Nitrogen-containing heterocycle *2 Confidential   BASF Corporation Results of a mouse micronucleus screening study
8EHQ-0702-15172A (PDF) p-Nitrotoluene 99-99-0 Y Bayer Corporation Results of a reproductive and developmental toxicity screening test via oral administration to rats
8EHQ-0702-15173A (PDF) Benzenesulfonic acid, hexadecyl (sulfophenoxy)-, disodium salt 65143-89-7 N Dow Chemical Company Results of a single dose oral toxicity study in rats (length of study not specified)
8EHQ-0702-15174A (PDF) Sulfonamide, substituted Confidential N BASF Corporation Results of a dietary 28-day toxicity study in rats
8EHQ-0702-15175A (PDF) Carbomonocyclic ether, substituted Confidential N National Starch and Chemical Company Final report of an intraperitoneal micronucleus study in mice
8EHQ-0702-15176A (PDF) Modified acrylic terpolymer Confidential   National Starch and Chemical Company Study report of an acute algal toxicity test
8EHQ-0702-15178A (PDF) Blue ink Confidential   Confidential Results of a local lymph node sensitization assay in mice
8EHQ-0702-15179A (PDF) Propane, 1-nitro 108-03-2 N Dow Chemical Company Results of a 28d repeat dose toxicity study with reproductive/developmental toxicity screening test in rats
8EHQ-0702-15180A (PDF) CGX RU 997 Confidential   Ciba Specialty Chemicals North America Study report of a guinea pig skin sensitization test
8EHQ-0702-15181A (PDF) Anthranilamide, substituted Confidential   Confidential Results of a 4 wk repeat dose toxicity study (via capsule) in dogs
8EHQ-0702-14281B (PDF) Propanoic acid, 3(dodecylthio)-, oxybis(2,1ethanediyloxy-2,1ethanediyl) ester 64253-30-1 Y Goodyear Tire & Rubber Company Final report of a four week dietary toxicity study in rats
8EHQ-0702-14381E (PDF) Long chain alkenyl amide borate Confidential   Confidential MSDS and precautionary label in response to EPA request
8EHQ-0702-14971C (PDF) 1-Methylcyclopropylamine, hydrochloride salt 88887-87-0 N Eastman Chemical Company Clarification on route of administration in previously reported four week oral toxicity study in rats
8EHQ-0702-15015B (PDF) Iodonium, (3methylphenyl) phenyl-, ar’C12–13 branched alkyl derivs., (OC-6-11) hexafluoroantimonates (1-) 309263-22-7 N Dow Corning Corporation Final report of skin sensitization study performed with guinea pig maximization test
8EHQ-0702-15067B (PDF) Chloroalkane byproducts 60027-77-2 N Vulcan Chemicals Results of 28-day repeat dose nose-only inhalation study in rats
Chloroalkane byproducts 23153-23-3 N
Chloroalkane byproducts 18993-24-3 N
8EHQ-0702-15149B (PDF) Pyridine ketone, substituted *2 Confidential N Syngenta Crop Protection, Inc. Preliminary results of a 28-day study in dogs (route of administration not stated)
8EHQ-0702-15155B (PDF) Textile chemical mixture None   Confidential Response to EPA request for information on potential exposures and voluntary risk management
Fluoroalkyl acrylate copolymer Confidential N
FYI-0702-01430A (PDF) Triethanolamine 102-71-6 Y National Institute of Environmental Health Sciences Pathology Working Group report and Summary Pathology Tables of a dermal two-year carcinogenicity and chronic toxicity study in mice
FYI-0702-01431A (PDF) Aspartame 22839-47-0 N EHS National Institutes of Environmental Health Sciences Pathology Working Group Report and Summary Pathology Tables of a 39week oral feeding prechronic toxicity and carcinogenicity study in transgenic mice
FYI-0702-01378AL (PDF) Perfluorooctane sulfonates and related compounds Multiple N 3M Company Final reports of an in vitro genotoxicity study, a 26-week oral toxicity study in monkeys, two pharmacokinetic studies, a drinking water health advisory, an acute toxicity study in earthworms, a bioconcentration study in fish, and environmental fate and

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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