TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received August 2003
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|8EHQ-0803-15392A (PDF)||Confidential *2||Confidential||N||Syngenta Crop Protection, Inc.||Results of an 18-month carcinogenicity study in mice by oral gavage|
|8EHQ-0803-15393A (PDF)||Sulfonamides, C4-8 alkane, perfluoro, N-(3 (dimethyloxi doamino)propyl), potassium salts||179005-06-2||N||Latham and Watkins, LLP||Final report of a subchronic 90-day oral gavage toxicity study in rats|
|8EHQ-0803-15394A (PDF)||3H-Pyrazol-3-one,2-(4 aminophenyl),4-dihydro-5 (1-pyrrolidinyl)||30707-77-8||N||Latham and Watkins, LLP||Final report of an acute oral toxicity study in rats, and acute dermal and eye irritation studies in rabbits|
|8EHQ-0803-15395A (PDF)||Confidential||Confidential||Latham and Watkins, LLP||Final report of a dermal sensitization study in guinea pigs|
|8EHQ-0803-15397A (PDF)||1H-Imidazolium, 1-ethenyl 3-methyl-, chloride, polymer with 1-ethenyl-2 pyrrolidinone||95144-24-4||N||BASF Corporation||Results of an acute toxicity study in algae|
|8EHQ-0803-15398A (PDF)||1H-Imidazolium, 1-ethenyl 3-methyl-, chloride, polymer with 1-ethenyl-2 pyrrolidinone||95144-24-4||N||BASF Corporation||Results of an acute toxicity study in algae|
|8EHQ-0803-15399A (PDF)||2,6-Octadienenitrile, 3,7 dimethyl||5146-66-7||N||BASF Corporation||Results of an in vitro chromosome aberration assay and an in vivo mouse micronucleus test|
|8EHQ-0803-15400A (PDF)||Azabicycloalkane *2||None||N||BASF Corporation||Results of an acute oral toxicity study in rats|
|8EHQ-0803-15401A (PDF)||Phenylacrylic acid methyl ester *2||None||N||BASF Corporation||Results of an acute oral toxicity study in rats|
|8EHQ-0803-15402A (PDF)||trans-Resveratrol||501-36-0||N||BASF Corporation||Results of an in vitro chromosome aberration assay in human lymphocytes and in vivo mouse micronucleus test|
|8EHQ-0803-15405A (PDF)||2,3-Dichloro-1,3-butadiene||1653-19-6||Y||DuPont Haskell Laboratory||Results of 2 inhalation toxicity studies in rats: a pilot developmental toxicity study and a 15-d repeated dose range-finding study|
|8EHQ-0803-15406A (PDF)||Hexaoxatricosane||143-29-3||Y||Rohm and Haas Company||Acute toxicity results of an oral 35-day repeated dose toxicity study in rats|
|8EHQ-0803-15407A (PDF)||Ethoxyethanol-tert butylamine||87787-67-5||N||NOVA Molecular Technologies, Inc.||Notification of availability of several toxicology reports which may have been submitted previously to EPA (PDF)|
|8EHQ-0803-15408A (PDF)||Resin oil, low dicyclopentadiene||684777-54-3 & 68516-20-1||Y||American Chemistry Council||Results of an oral gavage developmental toxicity study in rats|
|8EHQ-0803-15410A (PDF)||Fluorescent whitening agent||Confidential||N||Bayer Corporation||Results of a skin sensitization study in guinea pigs|
|8EHQ-0803-15411A (PDF)||Dibutyltin maleate||78-04-6||N||Parametrix, Inc.||Results of an acute toxicity study in daphnia|
|8EHQ-0803-15412A (PDF)||1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,1 0,10,10-heptadecafluoro||678-39-7||N||DuPont Haskell Laboratory||Results of a developmental toxicity study in rats (route of administration not stated, but appears to have been oral)|
|8EHQ-0803-00373AT (PDF)||Ammonium perfluorooctanoate||3825-26-1||N||Taft, Stettinius & Hollister, LLP||Chronology of events in DuPont's risk assessment and risk management activities related to PFOA (PDF)|
|8EHQ-0803-00373AU (PDF)||Ammonium perfluorooctanoate||3825-26-1||N||Taft, Stettinius & Hollister, LLP||Report of a model to estimate chemical exposure from blood levels in humans|
|8EHQ-0803-00373AV (PDF)||Perfluorooctanoic acid, ammonium salt||3825-26-1||N||Taft, Stettinius & Hollister, LLP||Final report of an investigation to evaluate adverse health effects in a herd of cattle|
|8EHQ-0803-15301C (PDF)||Amine/glycidyl ether||Confidential||Y||Confidential||Response to EPA request for information on chemical identity|
|8EHQ-0803-15302B (PDF)||Thioglycerol||96-27-5||N||Sumitomo Chemical America, Inc.||Withdrawal of TSCA confidential business information claim|
|FYI-0803-01450A (PDF)||Subtilisin variant (modified protease of Bacillus bacteria)||9014-01-1||N||Procter & Gamble Company||Results of a clinical allergenicity study in humans|
|FYI-0803-01453A (PDF)||Pentachlorodibenzofuran||57117-31-4||N||National Institute of Environmental Health Sciences||Pathology Working Group Report and Summary Pathology Tables of an oral gavage carcinogenicity and chronic toxicity study in rats|
|FYI-0803-01454A (PDF)||2,2',4,4',5,5'-Hexachlorobiphenyl||35065-27-1||N||National Institute of Environmental Health Sciences||Pathology working group report and summary pathology tables of an oral gavage carcinogenicity and chronic toxicity study in rats for toxic equivacy factor evaluation|
|FYI-0803-01455A (PDF)||Benzophenone||119-61-9||Y||National Institute of Environmental Health Sciences||Pathology working group report and summary pathology tables of an oral feeding carcinogenicity and chronic toxicity study in rats and mice|
|FYI-0803-01378AR (PDF)||Ammonium perfluorooctanoate||3825-26-1||N||3M Company||Report of groundwater and wastewater monitoring results at two chemical manufacturing sites|
|FYI-0803-01424C (PDF)||Hexabromocyclododecane||3194-55-6||Y||American Chemistry Council||Response to EPA comments concerning the conclusions of a 90-day oral gavage toxicity study submitted earlier.|
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.
Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.