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TSCA Section 8(e) Substantial Risk Notifications and FYI Submissions Received October 2004

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-1004-15707A (PDF) alpha-Methyl-3,4methylene-dioxyhydrocinamic aldehyde 1205-17-0 N Bayer Material Science Corporation Draft report of a developmental oral dose range-finding study in rats
8EHQ-1004-15708A (PDF) 2-Ethylhexyl phosphate 12645-31-7 Y Noveon, Inc. Results of an acute oral toxicity study in rats
8EHQ-1004-15709A (PDF) Alkenes, substituted Confidential   Confidential Results of an eye irritation screen in rabbits
8EHQ-1004-15710A (PDF) Modified spinosyn Confidential   Dow Chemical Company Results of a 28-day repeated dose oral dietary toxicity study in rats
8EHQ-1004-15711A (PDF) Nitrogen-containing heterocycle, substituted Confidential   BASF Corporation Results of acute studies in honey bees
8EHQ-1004-15712A (PDF) Nitrogen-containing heterocycle, substituted Confidential   BASF Corporation Results of acute toxicity studies in honey bees
8EHQ-1004-15713A (PDF) Pyrimidine, substituted Confidential   BASF Corporation Results of acute toxicity studies in honey bees
8EHQ-1004-15714A (PDF) Hydrazine, substituted Confidential   BASF Corporation Results of acute toxicity studies in honey bees
8EHQ-1004-15715A (PDF) Hydrazine, substituted Confidential   BASF Corporation Results of acute toxicity studies in honey bees
8EHQ-1004-15716A (PDF) Nitrogen-containing heterocycle, substituted Confidential N BASF Corporation Results of an acute toxicity study in Daphnia magna STRAUS
8EHQ-1004-15717A (PDF) Nitrogen-containing heterocycle, substituted Confidential   BASF Corporation Results of an acute toxicity study in Daphnia magna STRAUS
8EHQ-1004-15718A (PDF) Nitrogen-containing heterocycle, substituted Confidential   BASF Corporation Results of an acute toxicity study in Daphnia magna STRAUS
8EHQ-1004-15719A (PDF) Reaction product of a higher alcohol, a chlorinated aromatic and an anhydride Confidential   Confidential Results of a developmental toxicity study in rats (route of administration not stated)
8EHQ-1004-15720A (PDF) Pyrimidine, substituted Confidential   BASF Corporation Results of an acute toxicity study in Daphnia magna STRAUS
8EHQ-1004-15721A (PDF) Alkenes, substituted Unknown   Confidential Results of an eye irritation screening study in rabbits.
8EHQ-1004-15722A (PDF) Alkenes, substituted Unknown   Confidential Results of an eye irritation screening study in rabbits.
8EHQ-1004-15723A (PDF) 2,3,7,8Tetrachlorodibenzo-pdioxin 1746-01-6 N Dow Chemical Company Excerpts from a report on dioxin exposure - human serum testing
8EHQ-1004-15754A (PDF) Propanoic acid, 2-hydroxy, compound with 2ethylhexyl [[3-[[2(dimethylamino)ethoxy]car bonyl]amino]-4methylphenyl] carbamate (1:1) 68227-46-3 Y PPG Industries, Inc. Results of 4-week repeated dose toxicity and reproductive & developmental toxicity screening studies in rats by oral gavage
8EHQ-1004-15755A (PDF) 7-Oxa-3,20diazadispiro(5.1.11.2) heneicosan-21-one, 2,2,2,tetramethyl 64338-16-5 N Clariant Corporation Final report of an eye irritation study in rabbits (in German).
8EHQ-1004-15756A (PDF) Methyltrimethoxysilane 1185-55-3 Y Silicones Environmental, Health and Safety Council (SEHSC) Preliminary results of combined repeated dose toxicity study with a reproductive & developmental toxicity screening test in rats by oral gavage (OECD TG 422)
8EHQ-1004-15757A (PDF) Cyclohexylisocyanate 3173-53-3 Y Lanxess Corporation Results of an in vitro chromosome aberration test with Chenese hamster V79 cells
8EHQ-1004-15758A (PDF) Nitrogen-containing heterocycle, substituted Confidential   BASF Corporation Results of an acute toxicity test in daphnia
8EHQ-1004-15759A (PDF) Nitrogen-containing heterocycle, substituted Confidential   BASF Corporation Results of an acute toxicity test in daphnia
8EHQ-1004-15760A (PDF) Ethylphenol (mixed isomer) 25429-37-2 N MERISOL USA LLC Results of an in vitro chromosome aberrations assay in Chinese hamster ovary cells and an in vitro Ames bacterial mutation assay
p-Ethylphenol 123-07-9 Y  
o-Ethylphenol 90-00-6 Y  
m-Ethylphenol 620-17-7 Y  
8EHQ-1004-15761A (PDF) 2,3-Xylenol 526-75-0 Y MERISOL USA LLC Results of an in vitro chromosome aberrations assay in Chinese hamster ovary cells and an in vitro Ames bacterial mutation assay
2,4-Xylenol 105-67-9 Y  
2,5-Xylenol 95-87-4 Y  
2,6-Xylenol 576-26-1 Y  
3,4-Xylenol 95-65-8 Y  
3,5-Xylenol 108-68-9 Y  
Xylenol (mixed isomers) 1300-71-6 Y  
8EHQ-1004-15762A (PDF) Research pesticide *2 Confidential N Confidential Results of a 48-hour range-finding toxicity test in daphnia
8EHQ-1004-15763A (PDF) Research pesticide *2 Confidential N Confidential Results of a 48-hour range-finding toxicity test in daphnia
8EHQ-1004-15764A (PDF) Research pesticide *2 Confidential N Confidential Results of a 14-day oral toxicity study in northern bobwhite quail
8EHQ-1004-15765A (PDF) Chemical *2 Confidential N Confidential Results of an acute dermal toxicity study in rats
8EHQ-1004-15766A (PDF) Dihydrothiazole derivative Confidential   BASF Corporation Results of an acute toxicity study in fathead minnows
8EHQ-1004-15767A (PDF) Pyrimidine, substituted Confidential   BASF Corporation Results of a screening bioconcentration study in fathead minnows
8EHQ-1004-15768A (PDF) Flubendiamide Confidential   BayerMaterial Science Corporation Results of a reproductive toxicity study in rats (exposure route not stated)
8EHQ-1004-15769A (PDF) Dicyclohexylmethane-4,4'diisocyanate 5124-30-1 Y Bayer Material Science Corporation  Results of a 4-week inhalation toxicity study in rats
8EHQ-1004-15770A (PDF) Dicyclohexylmethane-4,4'diisocyanate 5124-30-1 Y Bayer Material Science Corporation  Results of a developmental toxicity study in rats by inhalation
8EHQ-1004-15771A (PDF) Dicyclohexylmethane-4,4'diisocyanate 5124-30-1 Y Bayer Material Science Corporation  Results of a reproductive and developmental toxicity screening test in rats by inhalation (OECD TG 421)
8EHQ-1004-15807A (PDF) Chemical Confidential   National Starch and Chemical Company  Final report of a local lymph node assay in mice
8EHQ-1004-15809A (PDF) 2,3,7,8Tetrachlorodibenzo-pdioxin 1746-01-6 N Dow Chemical Company  Abstract of an epidemiology study of workers exposed to phenoxy herbicides and dioxins
8EHQ-1004-15817A (PDF) Alkylazine Confidential   Bayer Material Science Corporation  Results of a 14-day dose range finding pilot and exploratory toxicity study in beagle dogs by oral gavage and dietary administration
8EHQ-1004-15849A (PDF) Developmental pesticide *2 Confidential N Confidential Results of an acute inhalation toxicity study in rats
8EHQ-1004-15859A (PDF) Organic fluorochemical mixture Multiple N 3M Company Results of an aquatic toxicity study in daphnia
8EHQ-1004-15860A (PDF) Organic fluorochemical mixture Multiple N 3M Company Results of a multigeneration life cycle test in daphnia
8EHQ-1004-15861A (PDF) Dibutyltin laurate 77-58-7 N 3M Company Results of 48-hour and 96-hour acute toxicity tests in daphnia with a mixture
Dibutyltin di(2ethylhexoate) 2781-10-4 N
8EHQ-1004-15862A (PDF) 1-Naphthalene-meth-anol, alpha,alpha-bis[4(diethylamino)phenyl]-4(ethylamino) 1325-86-6 N 3M Company Results of a 48-hour acute toxicity test in daphnia with a mixture
1,4-Bis[2-ethyl-hexyl) amino]anthraquinone *3 61814-09-3 N
Decosheen Gold Paste Pigment Unknown N
8EHQ-1004-15863A (PDF) Nonylphenoxypoly (oxyethylene)ethanol *3 9016-45-9 Y 3M Company Results of an acute toxicity study in fathead minnows
8EHQ-1004-15864A (PDF) Nonylphenoxypoly (oxyethylene)ethanol *3 9016-45-9 Y 3M Company Results of an acute toxicity study in fathead minnows
8EHQ-1004-15865A (PDF) N-Methyl perfluorooctanesulfonamid oethanol 24448-09-7 Y 3M Company Results of tests on octanol water partition coefficient, chemical oxygen demand, biodegradation, water solubility, soil adsorption coefficient, acute toxicity in daphnia and acute toxicity in bluegill sunfish
8EHQ-1004-15924A (PDF) Cobalt chloride, hexahydrate 7791-13-1 N 3M Company Results of an acute toxicity test in a Microtox system
8EHQ-1004-15925A (PDF) Cobalt chloride, hexahydrate 7791-13-1 N 3M Company Results of a respiration inhibition test in activated sludge
8EHQ-1004-15926A (PDF) Cobalt chloride, hexahydrate 7791-13-1 N 3M Company Results of an acute toxicity test in daphnia
8EHQ-1004-15927A (PDF) Cobalt chloride, hexahydrate 7791-13-1 N 3M Company Results of an acute toxicity test in fathead minnows
8EHQ-1004-15928A (PDF) Cobalt chloride, hexahydrate 7791-13-1 N 3M Company Results of a growth inhibition test in freshwater algae
8EHQ-1004-15929A (PDF) N-ethylperfluorooctanesulfona midoethanol 1691-99-2 Y 3M Company Results of a 21-day chronic reproduction study in daphnia
8EHQ-1004-15930A (PDF) Chemical Confidential   3M Company Final report of a study to evaluate the effects on emergence and growth of six terrestrial vascular plant species and the persistence of residual toxicity to one plant species
8EHQ-1004-15931A (PDF) Monomethyl ether of hydroquinone 150-76-5 Y 3M Company Results of an acute toxicity test in daphnia and in a Microtox system
8EHQ-1004-15932A (PDF) 2-Methylbutyl acrylate 44914-03-6 Y 3M Company Results of acute toxicity tests in a Microtox system
Isooctyl acrylate 29590-42-9 Y
Methylisoamyl acrylate Unknown N
2-Ethylhexyl acrylate *3 103-11-7 Y
8EHQ-1004-15933A (PDF) Fluorocarbon surfactants Confidential   3M Company Results of a study to evaluate inhibition of plant emergence and early seed growth in six crop plants
8EHQ-1004-15951A (PDF) Chemical Confidential   3M Company Results of a plant toxicity comparison study of effects on young seedling growth
8EHQ-1004-15952A (PDF) BETZ 1110 Polymer Unknown N 3M Company Results of a 7-day survival and reproductive toxicity study in aquatic invertebrates
8EHQ-1004-15953A (PDF) BETZ 1138 Polymer Unknown N 3M Company Results of a 7-day survival and reproductive toxicity study in aquatic invertebrates
8EHQ-1004-15954A (PDF) 1,6-Hexanediol diacrylate 13048-33-4 Y 3M Company Results of an acute toxicity study in daphnia
8EHQ-1004-15955A (PDF) Methyl isoamyl acrylate 18993-92-1   3M Company Results of a chronic reproductive bioassay in daphnia
8EHQ-1004-15956A (PDF) Acrylamide/acrylate polymer - Nalclear 7177 Unknown N 3M Company Final report of a 7-day chronic toxicity study in aquatic invertebrates
8EHQ-1004-15957A (PDF) Isooctyl acrylate 29590-42-9 Y 3M Company Final report of an acute toxicity study in daphnia
8EHQ-1004-15958A (PDF) Tolyltriazole *3 29385-43-1 Y 3M Company Final report of an acute toxicity study in daphnia
8EHQ-1004-15959A (PDF) Tolyltriazole *3 29385-43-1 Y 3M Company Final report of an acute toxicity study in algae
8EHQ-1004-15960A (PDF) Chemical Confidential   3M Company Final report of an acute toxicity study in daphnia
8EHQ-1004-15961A (PDF) Chemical Confidential   3M Company Final report of an acute toxicity study in fathead minnows
8EHQ-1004-15962A (PDF) Propylenetetrafluoroethylene polymer 27029-05-6 N 3M Company Final report of an acute toxicity study in daphnia
8EHQ-1004-15974A (PDF) Isooctyl acrylate 29590-42-9 Y 3M Company Final report of an acute toxicity test in fish
8EHQ-1004-15975A (PDF) Isooctyl acrylate 29590-42-9 Y 3M Company Final report of an acute immobilization test in daphnia
8EHQ-1004-15976A (PDF) Isooctyl acrylate 29590-42-9 Y 3M Company Final report of a growth inhibition test in algae
8EHQ-1004-15977A (PDF) Isooctyl acrylate 29590-42-9 Y 3M Company Final report of a reproduction test in daphnia
8EHQ-1004-15978A (PDF) Chemical Confidential   3M Company Final report of an acute toxicity test in mysid shrimp
8EHQ-1004-15979A (PDF) Chemical Confidential   3M Company Results of a 10-minute exposure Microtox test
8EHQ-1004-15980A (PDF) N-Methyl perfluorooctanesulfonamid oethanol 25268-77-3 N 3M Company Final report of partition coefficient determination of a mixture
N-Methyl perfluorooctanesulfonamid oethyl acrylate 24448-09-7 Y
8EHQ-1004-15981A (PDF) N-Dodecyltrimethylammonium chloride 112-00-5 Y 3M Company Results of an OECD activated sludge respiration inhibition test
8EHQ-1004-15982A (PDF) Cocamidopropyl betaine 70851-07-9 Y 3M Company Results of an acute toxicity study in fish with a mixture
Coco/Oleamidopropyl betaine *3 61789-40-0 Y
8EHQ-1004-15983A (PDF) Perfluorooctanesulfonate 1763-23-1 N 3M Company Final report of a flow-through life-cycle toxicity test in mysid shrimp
8EHQ-1004-15984A (PDF) Lithium chloride *3 7447-41-8 N 3M Company Final report of a flow-through life-cycle toxicity test in mysid shrimp
8EHQ-1004-15985A (PDF) Perfluorooctanesulfonate 1763-23-1 N 3M Company Final report of an early life-stage toxicity test in fathead minnows (OECD TG 210)
8EHQ-1004-15986A (PDF) Lithium chloride *3 7447-41-8 N 3M Company Final report of an acute toxicity test in fathead minnows (OECD TG 203)
8EHQ-1004-15987A (PDF) Lithium chloride *3 7447-41-8 N 3M Company Final report of an acute toxicity test in daphnia (OECD TG 202)
8EHQ-1004-15988A (PDF) Octane sulfonyl chloride 7795-95-1 Y 3M Company Results of aquatic toxicity testing in fish, daphnia, algae and microbial systems
Octane sulfonyl fluoride 40630-63-5 Y
8EHQ-1004-15989A (PDF) Lauryldimethylamineoxide *3 1643-20-5 Y 3M Company Results of a Microtox test
8EHQ-1004-15990A (PDF) Cobalt chloride, hexahydrate 7791-13-1 N 3M Company Results of aquatic toxicity testing in fish, daphnia, algae and microbial systems; results of phytotoxicity testing - effects on seed germination, root elongation and early seedling growth
8EHQ-1004-00373BJ (PDF) N-Methyl perfluorooctanesulfonamide 2355-31-9 N 3M Company Final report of a 28-day repeated-dose dermal toxicity study in rats
Perfluorooctane sulfonate (PFOS) 2795-39-3 N
Perfluorohexanesulfonate 355-46-4 Y
8EHQ-1004-15196E (PDF) 1-Phenyl-ethanone 98-86-2   Acetophenone Task Force Response to EPA request for additional information
8EHQ-1004-15708B (PDF) 2-Ethylhexyl phosphate 12645-31-7 Y Noveon, Inc. Final report of an acute oral toxicity study in rats
FYI-1004-01480A (PDF) Ammonium perfluorooctanoate 3825-26-1 N Taft, Stettinius & Hollister, LLP Results of blood monitoring of humans living near the chemical production facility and exposed to PFOA through drinking water
FYI-1004-01481A (PDF) Polychlorinated biphenyl mixture: PCB 126/PCB 118 1336-36-3 N National Institute of Environmental Health Sciences Summary Pathology Tables of an oral gavage carcinogenicity and chronic toxicity study in rats for toxic equivalency factor (TEF) evaluation
FYI-1004-01482A (PDF) Polychlorinated biphenyl mixture: PCB 126/PCB 153 1336-36-3 N National Institute of Environmental Health Sciences Summary Pathology Tables of an oral gavage carcinogenicity and chronic toxicity study in rats for toxic equivalency factor (TEF) evaluation

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.

FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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