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8(e) and FYI Submissions Received April 2009
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8EHQ# |
CHEM NAME(S) |
CAS NO.(S) |
USHV |
SUBMITTER |
DESCRIPTION |
| 8EHQ-0409-17350A (PDF) (1 pg, 34K) |
Confidential | Confidential | Confidential | Response to EPA request for additional information, dated April 13, 2009. | |
| 8EHQ-0409-17466A (PDF) (2 pp, 195K) |
Asphalt fume condensate (LR-A) | None | Y | Asphalt Institute | Draft report of a mouse skin carcinogenicity study. |
| Asphalt fume condensate (TR-A) | None | ||||
| Type III (Built Up Roofing) oxidized roofing asphalt | 64742-93-4 | ||||
| 8EHQ-0409-17467A (PDF) (5 pp, 312K) |
Busperse 293 | None | Buckman Laboratories International, Inc. | Incident report filed by Buckman Laboratories regarding adverse effects resulting from alleged occupational exposure. | |
| 8EHQ-0409-17468A (PDF) (2 pp, 158K) |
Halogenated pyridine derivative | Confidential | Dow Chemical Company | Results of an oral developmental toxicity study in rats. | |
| 8EHQ-0409-17469A (PDF) (2 pp, 144K) |
Isoxazole, substituted | Confidential | Syngenta Crop Protection, Inc. | Information from two 28-day dietary toxicity studies in the rat and mouse. | |
| 8EHQ-0409-17470A (PDF) (2 pp, 143K) |
Isoxazole, substituted | Confidential | Syngenta Crop Protection, Inc. | Results from two 28-day dietary toxicity studies in the rat and mouse. | |
| 8EHQ-0409-17471A (PDF) (1 pg, 120K) |
Pyrazole, substituted | Confidential | Syngenta Crop Protection, Inc. | Results of a 28-day dietary study in rats. | |
| 8EHQ-0409-17472A (PDF) (2 pp, 204K) |
Halogenated pyridine derivative | Confidential | Dow Chemical Company | Results of a 28-day dietary toxicity study in rats. | |
| 8EHQ-0409-17473A (PDF) (2 pp, 148K) |
Halogenated pyridine derivative | Confidential | Dow Chemical Company | Results of a dietary developmental toxicity study in rats. | |
| 8EHQ-0409-17474A (PDF) (2 pp, 132K) |
Halogenated pyridine derivative | Confidential | Dow Chemical Company | Results of a 2-year chronic toxicity/oncogenicity study in rats. | |
| 8EHQ-0409-17475A (PDF) (2 pp, 144K) |
Halogenated pyridine derivative | Confidential | Dow Chemical Company | Results of a 90-day dietary toxicity study in rats. | |
| 8EHQ-0409-17476A (PDF) (1 pg, 113K) |
2,3,4,7,8-Pentachlorodibenzofuran (4-PeCDF) | 57117-31-4 | N | Dow Chemical Company | Results of a repeated-dose/reproductive/developmental dietary toxicity study in ranch mink. |
| 2,3,7,8-Tetrachlorodibenzofuran (TCDF) | 51207-31-9 | N | |||
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) | |||||
| -56240 | N | ||||
| 8EHQ-0409-17477A (PDF) (3 pp, 253K) |
Aminoethylethanolamine (AEEA) *3 | 111-41-1 | Y | Ethyleneamines Product Stewardship Discussion Group (EPSDG) Aminoethylethanolamine (AEEA) Testing Consortium | Interim resulst of a preliminary developmental oral (gavage) toxicity study in rats. |
| 8EHQ-0409-17478A (PDF) (1 pg, 122K) |
Di-n-octyl phthalate (DnOP) | None | Wal-Mart Stores, Inc. | A letter to providing contact information for the Consumer Product Safety Commission (CPSC) so that EPA can review the contents of various product removal reports on individually recalled items related to lead and/or phthalate contamination. | |
| Di-(2-ethylhexyl) phthalate (DEHP) | None | ||||
| Dibutyl phthalate (DBP) | None | ||||
| Diisodecyl phthalate (DIDP) | None | ||||
| Diisononyl phthalate (DINP) | None | ||||
| Benzyl butyl phthalate (BBP) | None | ||||
| 8EHQ-0409-17479A (PDF) (2 pp, 207K) |
Dimethylterephthalate (DMT) | 120-61-6 | Y | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of 4 pre-1977 (1951-58) repeated oral toxicity studies in rats (3) and dogs (1). |
| 8EHQ-0409-17480A (PDF) (1 pg, 120K) |
Dichloroacetyl chloride | 79-36-7 | Y | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a pre-1977 (1955) acute oral toxicity study in rats. |
| 8EHQ-0409-17481A (PDF) (6 pp, 479K) |
Alkyl heteroalkyl chloride *1 | Confidential | Confidential | Preliminary findings of a skin sensitization and acute oral toxicity study. | |
| 8EHQ-0409-17482A (PDF) (4 pp, 105K) |
Confidential | Confidential | Confidential | Results of an acute inhalation toxicity test in rats | |
| 8EHQ-0409-17483A (PDF) (30 pp, 1.13MB) |
Octamethylcyclotetrasiloxane (D4) *3 | 556-67-2 | Y | Silicones Environmental Health and Safety Council | Results of a 2-generation reproductive toxicity study in rats, including a developmental neurotoxicity assessment. |
| 8EHQ-0409-17484A (PDF) (4 pp, 161K) |
Hydrocarbyl aldehyde | Confidential | Keller and Heckman LLP | Preliminary findings from a 5 day oral gavage study in rats | |
| 8EHQ-0409-17485A (PDF) (3 pp, 126K) |
Para-tert-butylbenzaldehyde | 939-97-9 | Y | BASF Corporation | Results of an acute toxicity study in water fleas |
| 8EHQ-0409-17486A (PDF) (2 pp, 73K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Results of a combined chronic toxicity/carcinogenicity study in wistar rats | |
| 8EHQ-0409-17487A (PDF) (2 pp, 72K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Results of a toxicity study with green algae | |
| 8EHQ-0409-17488A (PDF) (2 pp, 72K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Results of a toxicity study with green algae | |
| 8EHQ-0409-17489A (PDF) (2 pp, 72K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Results of a toxicity study with green algae | |
| 8EHQ-0409-17490A (PDF) (5 pp, 165K) |
Nitrogen containing heterocycle, substituted (Substances A, B, C, D, E, F) *2 | Confidential | BASF Corporation | Results of screening tests on acute toxicity in fathead minnow | |
| 8EHQ-0409-17491A (PDF) (2 pp, 87K) |
Carboxamide | Confidential | Bayer CropScience LP | Results of a repeated-dose oral toxicity study in rats (hepatotoxicity and thyroid hormone investigation). | |
| 8EHQ-0409-17492A (PDF) (2 pp, 115K) |
Carboxamide | Confidential | Bayer CropScience LP | Results of a developmental oral toxicity study in rabbits | |
| 8EHQ-0409-17493A (PDF) (2 pp, 68K) |
2,4,4-trimethyl-2-pentanamine | 107-45-9 | Y | Rohm and Haas Chemicals LLC | Results of an oral 28-day repeated-dose toxicity study in rats |
| 8EHQ-0409-17494A (PDF) (3 pp, 102K) |
Confidential | Confidential | Confidential | Results of a one generation reproductive dietary toxicity study in rats | |
| 8EHQ-0409-17495A (PDF) (2 pp, 105K) |
Confidential | Confidential | Confidential | Results of an oral developmental toxicity study in Wistar rats | |
| 8EHQ-0409-17496A (PDF) (2 pp, 79K) |
Confidential | Confidential | Confidential | Results of a one-generation dietary reproductive toxicity study in rats. | |
| 8EHQ-0409-17497A (PDF) (1 pg, 55K) |
2-Butenoic acid ester | Confidential | The Dow Chemical Company | Results of an acute inhalation toxicity study in rats | |
| 8EHQ-0409-17498A (PDF) (1 pg, 57K) |
Phenyl isothiocyanate (PITC) | Confidential | Life Technologies | Customer report regarding health effect of product. | |
| 8EHQ-0409-17499A (PDF) (2 pp, 86K) |
Nitrogen containing heterocycle, substituted *2 | Confidential | BASF Corporation | Interim results of a preliminary range-finding oral prenatal developmental toxicity study in rats. | |
| 8EHQ-0409-17500A (PDF) (2 pp, 107K) |
2-Methyl-2-buten | 513-35-9 | BASF Corporation | Preliminary results of an in vivo mouse micronucleus test. | |
| 8EHQ-0409-17501A (PDF) (48 pp, 3.15MB) |
Ethanol, 2,2'-iminobis- (diethanolamine) *3 | 111-42-2 | Y | The Dow Chemical Company | Results of a dermal developmental/reproductive toxicity study in rats. |
| 8EHQ-0409-00373CX (PDF) (32 pp, 2.80MB) |
Fluorochemicals, sulfonate-based and carboxylic-based *1 | Multiple | N | 3M Corporation | Results of fluorochemical analysis of 33 fish fillet tissues of walleye, northern pike, sauger, bluegill, smallmouth bass and black crappie as split samples collected by the Minnesota Pollution Control Agency (MPCA) from the Mississippi River. |
| 8EHQ-0409-00373CY (PDF) (44 pp, 4.04MB) |
Fluorochemicals, sulfonate-based and carboxylic-based *1 | Multiple | N | 3M Corporation | Results of a fluorochemical analytical method validation study in which fish tissues, purchased from Osage Catfisheries, Inc. (Osage Beach, MO), were used as control samples. |
| 8EHQ-0409-13853C (PDF) (1 pg, 116K) |
Quinazolinone | Confidential | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a skin irritation study in rabbits. | |
| 8EHQ-0409-15945U (PDF) (1 pg, 171K) |
Anthranilamide, substituted | Confidential | Confidential | Results of a developmental toxicity study in rabbits. | |
| 8EHQ-0409-16105P (PDF) (1 pg, 59K) |
Thiophene derivative, substituted | Confidential | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an acute inhalation toxicity study in rats. | |
| 8EHQ-0409-16446J (PDF) (9 pp, 296K) |
Perfluorooctanoic acid (PFOA) | 335-67-1 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Updated occupational serum sample results from the Washington Works Parkersburg, West Virginia facility among other facilities. |
| 8EHQ-0409-16446K (PDF) (8 pp, 286K) |
Perfluorooctanoic acid (PFOA) | 335-67-1 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Updated serum sampling results from the Dordrecht Works, Dordrecht, Netherlands facility among other facilities. |
| 8EHQ-0409-16929B (PDF) (2 pp, 89K) |
Ethylene | 74-85-1 | Y | Olefins Panel of the American Chemistry Council | Supplemental results/evaluation of a previously conducted 90-day inhalation toxicity study in rats and preliminary results of a second 90-day inhalation study in rats. |
| 8EHQ-0409-17079E (PDF) (70 pp, 4.73MB) |
Sepiolite S-9 | 63800-37-3 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Final report of a pulmonary bioassay screening study in rats. |
| 8EHQ-0409-17353B (PDF) (28 pp, 1.63MB) |
Oxirane, 2-[(bicyclo[2.2.l]hept-5-en-2-ylmethoxy)yl]- *1 | 3188-75-8 | N | Promerus, LLC | Results of a micronucleus study in mice. In the transmittal letter, the submitter states "Promerus relinquishes confidentiality claims on this and an earlier submission in the series, 8EHQ-08-17353". |
| 8EHQ-0409-17365C (PDF) (2 pp, 73K) |
Octanoic acid, 4,4,5,5,6,6,7,7,8,8,8-undecafluoro- | None | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a dermal sensitization study in mice using the local lymph node assay (LLNA). |
(A) PMN; (B) Pesticide; (C) Pesticide Inert
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and
year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter
( “A” for the initial
submission and “B”, “C”, “D”, etc. for
supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the
same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to
request a copy of a submission.FYI (For Your
Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is
similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter
either judges that the information is not reportable under TSCA 8(e) reporting
requirements or is not subject to TSCA 8(e) reporting but wants to share the
information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other
EPA programs and other federal agencies can ask OPPT to request follow-up
information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI"
indicates that the submitter is claiming the identity of the chemical to be
confidential business information. This claim can be challenged in some cases,
and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture
and importation. EPA defines high production volume as annual production one
million pounds or more pounds.
Description - A general description of the type of study or information submitted,
but not study results. A PDF electronic copy of the submission is attached.