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8(e) and FYI Submissions Received May 2009
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8EHQ# |
CHEM NAME(S) |
CAS NO.(S) |
USHV |
SUBMITTER |
DESCRIPTION |
| 8EHQ-0509-13171A (PDF) (2 pp, 102K) |
2-Amino-2-methylpropanenitrile | 19355-69-2 | Y | DuPont Haskell Global Centers | Results of a combined repeated dose toxicity study in rats with a reproduction/developmental toxicity screening test. |
| 8EHQ-0509-17399A (PDF) (533 pp, 10.29MB) |
Tertiary butyl alcohol *3 | 75-65-0 | Y | Lyondell Chemical Company | Final report of a 14-day oral (drinking water) toxicity study in mice. |
| 8EHQ-0509-17504A (PDF) (2 pp, 103K) |
Fluoroalkyl phosphoryl chloride | Confidential | Confidential | Results of an acute oral toxicity study in rats and mice. | |
| 8EHQ-0509-17505A (PDF) (2 pp, 64K) |
Mixture of substituted isothiazolone and solvent | Confidential | Confidential | Effects from an acute toxicity study in fish. | |
| 8EHQ-0509-17506A (PDF) (2 pp, 62K) |
Mixture of substituted isothiazolone and solvent | Confidential | Confidential | Effects from an aquatic toxicity study in green algae. | |
| 8EHQ-0509-17507A (PDF) (1 pg, 56K) |
Confidential | Confidential | Confidential | Results of an acute toxicity study in Daphnia magna. | |
| 8EHQ-0509-17508A (PDF) (2 pp, 84K) |
Nitrogen containing heterocycle | Confidential | BASF Corporation | Results of an acute eye irritation test in rabbits. | |
| 8EHQ-0509-17509A (PDF) (2 pp, 80K) | Nitrogen containing heterocycle *2 | Confidential | BASF Corporation | Results of a 12-month dietary toxicity study in Beagle dogs. | |
| 8EHQ-0509-17510A (PDF) (2 pp, 121K) |
Phenyl substituted aldehyde | Confidential | Confidential | Preliminary results from a 14-day oral toxicity study in rats. | |
| 8EHQ-0509-17511A (PDF) (2 pp, 126K) |
Hydrocarbon aldehyde | Confidential | Confidential | Preliminary results from a 14-day oral toxicity study in rats. | |
| 8EHQ-0509-17512A (PDF) (2 pp, 68K) |
Confidential | Confidential | Confidential | Results of an acute inhalation toxicity study in rats. | |
| 8EHQ-0509-17513A (PDF) (1 pg, 57K) |
Ethyl urea | 625-52-5 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a pre-1977 (1974) acute oral toxicity study in rats. |
| 8EHQ-0509-17514A (PDF) (1 pg, 80K) |
Nitrogen containing heterocycle, substituted | Confidential | Confidential | Results of an in vivo mouse micronucleus assay. | |
| 8EHQ-0509-17515A (PDF) (1 pg, 53K) |
Nitrogen containing heterocycle, substituted | Confidential | Confidential | Results of an acute algal assay. | |
| 8EHQ-0509-17516A (PDF) (1 pg, 66K) |
1,1,2,3,3,3-Hexafluoropropyl2,2,2-trifluoroethyl ether | 993-95-3 | N | 3M Corporation | Preliminary data from an acute inhalation toxicity study in rats. |
| 8EHQ-0509-17517A (PDF) (2 pp, 90K) | Poly[oxy(methyl-1,2-ethanediyl)],.alpha.-butyl-.omega.-hydroxy- *3 | 9003-13-8 | N | Dow Chemical Company | Results of a 23-day preliminary oral dose range-finding study in rats. |
| 8EHQ-0509-17518A (PDF) (1 pg, 53K) |
Amide mixture | Confidential | Confidential | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0509-17519A (PDF) (1 pg, 57K) |
Petroleum distillates, aromatic acid and aromatic compound mixture | Confidential | Confidential | Results of an acute oral and an acute inhalation toxicity study in rats. | |
| 8EHQ-0509-17520A (PDF) (1 pg, 62K) |
Petroleum distillates and aromatic acid mixture | Confidential | Confidential | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0509-17521A (PDF) (2 pp, 84K) |
Formyloxymandeloyl chloride | 29169-64-0 | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an eye irritation test, skin irritation test and an acute inhalation toxicity study. | |
| 8EHQ-0509-17522A (PDF) (1 pg, 59K) |
Amine and amide mixture | Confidential | Confidential | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0509-17523A (PDF) (1 pg, 72K) |
Benzamine, 2,6-dimethyl- | 87-62-7 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an acute dermal toxicity study in rabbits. |
| 8EHQ-0509-17524A (PDF) (1 pg, 66K) |
Ethyl 4-nitrobenzoate | 99-77-4 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an acute oral toxicity study in rats. |
| 8EHQ-0509-17525A (PDF) (2 pp, 84K) |
Benzenamine, 2,4-dimethyl- | 95-68-1 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an eye irritation test in rabbits and a skin sensitization study in guinea pigs. |
| 8EHQ-0509-17526A (PDF) (2 pp, 129K) |
N,N-dimethyl-p-toluidine | 99-97-8 | Y | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an eye irritation test, skin irritation test, skin sensitization test, an acute oral toxicity study and a study to evaluate methemoglobin formation. |
| 8EHQ-0509-17527A (PDF) (1 pg, 58K) |
Confidential | Confidential | Confidential | An acute oral toxicity study with Petroleum Distillates, Aromatic Acid, Aromatic Compound, and Glycol Ethers. | |
| 8EHQ-0509-17528A (PDF) (1 pg, 56K) |
Petroleum distillates, aromatic acid, aromatic compound and glycol ethers, mixture | Confidential | Confidential | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0509-17529A (PDF) (2 pp, 117K) |
N-ethyl-N-hydroxyethyl-m-toluidine | 91-88-3 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an acute oral toxicity study, eye irritation test, skin sensitization test and an acute inhalation toxicity study. |
| 8EHQ-0509-17530A (PDF) (2 pp, 68K) |
Perfluorohexanoate anion (PFHxA) | 307-24-4 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results (2009) of serum sampling from workers at the Washington Works, Parkersburg, West Virginia facility. |
| 8EHQ-0509-17531A (PDF) (2 pp, 91K) |
Pentanoic acid, nonafluoro | 2706-90-3 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of acute toxicity studies in freshwater green algae and fathead minnows. |
| 8EHQ-0509-17532A (PDF) (1 pg, 62K) |
Dimethyl (dehydrogenated tallow) (C16-C18) ammonium chloride (70% active ingredient in isopropyl alcohol) | 61789-80-8 | Y | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a pre-1977 (1968) acute oral toxicity study in rats. |
| 8EHQ-0509-17533A (PDF) (1 pg, 63K) |
4-chloro-alpha-(1-methylethy1)-benzeneacetic acid-phenylethylamine | None | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of an acute oral toxicity study in rats. | |
| 8EHQ-0509-17534A (PDF) (1 pg, 58K) |
1 -(2-cyanoacetyl)-3-ethyl urea | 41078-06-2 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a pre-1977 (1974) acute oral toxicity study in rats. |
| 8EHQ-0509-17535A (PDF) (2 pp, 110K) |
Halogenated pentanol | Confidential | Confidential | Results of pre-1977 acute oral, inhalation, and dermal toxicity studies as well as a screening study for anesthetic properties. | |
| 8EHQ-0509-17536A (PDF) (21 pp, 675K) |
Cardolite NC-513 epoxy diluent | 171263-25-5 | N | Cardolite Corporation | Results of a local lymph node assay in the mouse. |
| 8EHQ-0509-15945V (PDF) (2 pp, 113K) |
Anthranilamide, substituted | Confidential | DuPont Haskell Global Centers for Health and Environmental Sciences | Preliminary results of a 2-year feeding study in rats. | |
| 8EHQ-0509-16916F (PDF) (2 pp, 118K) |
Fluoroalkyl carboxylic acid, ammonium salt | Confidential | Confidential | Preliminary results of a 7-day repeated-dose toxicity study in rats and mice. | |
| 8EHQ-0509-17279B (PDF) (2 pp, 88K) |
2-Propenoic acid, 2-methyl-, 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester | 2144-53-8 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Results of a repeated-dose oral toxicity study in rats. |
| 8EHQ-0509-17323B (PDF) (3 pp, 107K) |
3-Nitro-4-octanol | 252254-51-6 | N | Dow Chemical Company | Response to a request by EPA regarding the correct CAS number for submission 8EHQ_1108_17323A |
| 8EHQ-0509-17458B (PDF) (1 pg, 48K) |
2-Thiophenecarboxylic acid, 3-(isocyanatosulfonyl)-, methyl ester | 79277-18-2 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Response to EPA's request dated May 6, 2009 (received May 11, 2009) for the correct CAS number of the test substance identified in the submitter's letter on March 26, 2009. |
| 8EHQ-0509-17440B (PDF) (3 pp, 199K) |
Fluoroalkyl phosphoric acid salt, aqueous solution | Confidential | Confidential | Results of a repeated dose oral toxicity study in rats and mice. | |
| 8EHQ-0509-17450B (PDF) (4 pp, 232K) |
Dimethoxydimethylsilane | 1112-39-6 | N | Silicones Environmental, Health and Safety Council (SEHSC) | Histopathological findings from a combined repeated-dose toxicity study with a reproductive/ developmental screening test in rats. |
| 8EHQ-0509-17458B (PDF) (1 pg, 48K) |
2-Thiophenecarboxylic acid, 3-(isocyanatosulfonyl)-, methyl ester | 79277-18-2 | N | DuPont Haskell Global Centers for Health and Environmental Sciences | Response to EPA's request dated May 6, 2009 (received May 11, 2009) for the correct CAS number of the test substance identified in the submitter's letter on March 26, 2009. |
| 8EHQ-0509-17459B (PDF) (2 pp, 102K) |
Hydroxy-chloro-cyclopropyl-heteromonocycliccarboxylic acid | Confidential | Confidential | Results of an acute inhalation toxicity study and an oral developmental toxicity study in rats. | |
| FYI-0509-01613 (PDF) (79 pp, 1.60MB) | Sandospace S: Benzenesulfonic acid, 4-[[4-chloro-6-(1-methylethoxy)- l,3,5- triazin-2-yl]amino]-, sodium salt (1:1) | 68413-55-8 | N | Clariant Corporation | Results of a guinea pig sensitization study and a human repeat insult patch test. |
(A) PMN; (B) Pesticide; (C) Pesticide Inert
DEFINITION OF TERMS
8EHQ# - This is the EPA submission number that includes a 4-digit month and
year followed by a 5-digit
number assigned sequentially from the year 1977, followed by a sequence letter
( “A” for the initial
submission and “B”, “C”, “D”, etc. for
supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the
same 5-digit sequential number
as a link to the initial submission. 8EHQ number is a useful reference to
request a copy of a submission.FYI (For Your
Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is
similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter
either judges that the information is not reportable under TSCA 8(e) reporting
requirements or is not subject to TSCA 8(e) reporting but wants to share the
information with EPA (and the public) on a voluntary basis.
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other
EPA programs and other federal agencies can ask OPPT to request follow-up
information as well.
CHEM Name - This is the name used by the submitter.
CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI"
indicates that the submitter is claiming the identity of the chemical to be
confidential business information. This claim can be challenged in some cases,
and users should notify EPA if they wish to pursue the chemical identity.
USHV - High production volume chemical in the U.S., including domestic manufacture
and importation. EPA defines high production volume as annual production one
million pounds or more pounds.
Description - A general description of the type of study or information submitted,
but not study results. A PDF electronic copy of the submission is attached.