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Section 8(e) Substantial Risk Notifications and FYI Submissions Received December 2010

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
SUBMITTER
USHV
DESCRIPTION
8EHQ-1210-18197A (PDF) Hexamethylenediamine 124-09-4 DuPont   Results of pre- 1977 DuPont studies with H-examethylenediamine (CASRN 124-09-4). In addition, DuPont received information from a third party also with the above-referenced test substance.
8EHQ-1210-18199A (PDF) Ethylene 74-85-1 Equistar Chemicals LP (Equistar) /Lyondellbasell   Preliminary and screening test results reported for a 4-week (20-day) ethylene (CASRN 74-85-1) inhalation study.
8EHQ-1210-18200A (PDF) Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 6731-36-8 Akzo Nobel Polymer Chemicals LLC   Preliminary results from a OECD 202 Daphnia Acute Immobilization Test on di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide (CASRN 6731-36-8).
8EHQ-1210-18201A (PDF) Multi-Walled Carbon Nanotube Not Provided Showa Denko Carbon, Inc. and Showa Denko America Inc.   Preliminary results from a recently conducted toxicity test conducted in rats exposed to a multi-walled carbon nanotube substance.
8EHQ-1210-18202A (PDF) Confidential Confidential Confidential   Results of a local lymph node assay (LLNA) with a formulation containing a CBI substance.
8EHQ-1210-18203A (PDF) Confidential Confidential Confidential   Results of a Test Study in Female, Non- Pregant Wistar rats with (substance A) and (Substance B)
8EHQ-1210-18204A (PDF) Confidential Confidential Confidential   Results of an Acute Toxicity Study on Honey Bees.
8EHQ-1210-18205A (PDF) Confidential Confidential Confidential   Results of an Acute Toxicity Study in Common Carp (Wild-Type, Cyprinus carplo) with a Formulation Containing a CBI substance.
8EHQ-1210-18206A (PDF) Methyl tertiary-butyl ether 1634-04-4 Shell Downstream Inc.   Results of a two-year combined chronic toxicity/carcinogenicity drinking water study in Wistar rats with methyl tertiary-butyl ether (MTBE CASRN 1634-04-4).
8EHQ-1210-18207A (PDF) (Ethanol, 2,2'-oxybis-, reaction products with ammonia, morpholine derivs. Residues 68909-77-3 BASF   Results of a Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in Wistar Rats [Crl:WI(HAN) Charles River, Sulzfeld, Germany], administration via gavage, according to OECD Guideline 422 with Amix M (Ethanol,
8EHQ-1210-18208A (PDF) Laurylamine 124-22-1 Dupont   Results of pre- 1977 (1937) toxicity studies, which we recently became aware of with the Laurylamine (CASRN 124-22-1).
8EHQ-1210-18209A (PDF) Ethylenediamine 107-15-3 DuPont   Results of pre- 1977 (193 7) toxicity studies, which we recently became aware of with the ethylenediamine (CASRN 107-15-3).
8EHQ-1210-18210A (PDF) Confidential Confidential Syngenta   Result of a 28 Day Oral Toxicity Study In Dogs with a Substituted Isoxazole. Third Submission
8EHQ-1210-18211A (PDF) Copper Beryllium Alloy 7440-50-8,
7440-41-7,
7440-48-4
DuPont   Occupational exposer to a copper beryllium alloy (CASRNs 7440-50-8 (copper), 7440-41-7 (beryllium), 7440-48-4 (cobalt)
8EHQ-1210-18212A (PDF) Distillates (petroleum), light catalytic cracked (LCC) gas oil 64741-59-9 Exxon Mobil   The effects of distillates (petroleum), light catalytic cracked (LCC) gas oil, CASRN 64741-59-9 on Pseudokirchneriella subcapitata and Daphina magna.
8EHQ-1210-18213A (PDF) 2-(diethylamino)ethyl ester, polymer with methyl 2-methyl-2-propenoate 27027-16-3 BASF   Results of a Prenatal Developmental Toxicity Study in Himalayan Rabbits with 2-Propenoic acid, 2-methyl-, 2-(diethylamino)ethyl ester, polymer with methyl 2-methyl-2-propenoate (CASRN 27027-16-3).
8EHQ-1210-18214A (PDF) Confidential Confidential Confidential   Results of a Growth Inhibition Test on Green Algae (Pseudokirchneriella subcapitata) with a Formulation Containing Two Active Ingredients.
8EHQ-1210-18215A (PDF) Confidential Confidential Dow   Results of a dietary developmental toxicity probe study with halogenated pyridine derivative.
8EHQ-1210-18216A (PDF) Vanadium Ppentoxide 1314-62-1 Vanadium Producers and Reclaimers Association   A preliminary results from an acute inhalation toxicity study on granular vanadium pentoxide (V2O5 CASRN 1314-62-1).
8EHQ-1210-18217A (PDF) Formaldehyde 50-00-0 DuPont   Results of two inhalation studies in rats with formaldehyde (CASRN 50-00-0).
8EHQ-1210-18218A (PDF) Light Catalytic Cracked Gas Oil Not Provided American petroleum Institute (API)   Results of  acute immobilization  of Daphnia magna using the Water Accommodated Fractions method of a Light Catalytic Cracked Gas Oil.
8EHQ-1210-18219A (PDF) 1,1 '-(1,1 ,4,4-tetramethyl-1, 4-butanediyl)bis[2-(1 , 1-dimethylethyl)] 78-63-7 AkzoNobel   The results from a dose range finding study on Peroxide, 1,1 '-(1,1 ,4,4-tetramethyl-1, 4-butanediyl)bis[2-(1 , 1-dimethylethyl)], CASRN 78-63-7.
8EHQ-1210-18220A (PDF) Light and Heavy Cracked Diesel Oil and Light Cracked Gas Oil 64741-59-9 Shell   Results of aquatic invertebrates and algae with Light and Heavy Cracked Diesel Oil and Light Cracked Gas Oil (CASRN 64741-59-9).
8EHQ-1210-16917D (PDF) 1,2,3,3,3-pentafluoropropene 5528-43-8 Mexichem Fluor Inc.   The systemic toxic potential of R- 1225 yeZ (a refrigerant) to Cr1 :CDO (SD) LOS BR rats by inhalation administration over a period of 28 or 90 days.
8EHQ-1210-18042C (PDF) Methyl 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino] carbonyllaminolsulfonyl]-6-(trifluoromethyl)-3-pyridinecarboxylate monosodiumn salt 144740-54-5 DuPount   The results of an acute toxicity study in daphnia magna, with a proprietary mixture containing 50% of Methyl 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyllaminolsulfonyl]-6-(trifluoromethyl)-3-pyridinecarboxylate monosodiumn salt (CASRN 144740-54-5).
8EHQ-1210-18043B (PDF) phenyl oxadiazole compound Not Provided Monsanto Company   Preliminary results from three studies with (an experimental phenyl oxadiazole compound) , currently being evaluated as a potential pesticide. As summarized below, those studies are: 1) a rat reproductive range-finding study; 2) a 28-day dog range finding study; and 3) a 90-day rat study.
8EHQ-1210-18164B (PDF) Phenyl oxadiazole compound *2 Not Provided Monsanto Company   Preliminary results have been obtained from a pilot rat developmental/teratology study, a pilot rabbit developmental/teratology study, and a 28-day rat study with an experimental phenyl oxadiazole compound, currently being evaluated as a potential pesticide.

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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