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Section 8(e) Substantial Risk Notifications and FYI Submissions Received March 2010

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0310-17848A (PDF) Fluorocarbon Not Provided   Confidential Results of an acute cardiac sensitization study in Beagle dogs
8EHQ-0310-17851A (PDF) Halogenated Pyridine derivative Not provided   Dow Chemical Company Results of a reproductive and developmental toxicity study in rats
8EHQ-0310-17853A (PDF) Toluene diisocyanate Not provided   Bayer MaterialScience Results of a Local Lymph Node Assay in Mice
8EHQ-0310-17854A (PDF) p-Cresolmethylether 104-93-8 Y BASF Chemical Company Results of a Reproduction/ Developmental Toxicity Screening Test in Wistar Rats
8EHQ-0310-17855A (PDF) 2,6-Octadien-1-01, 3,7dimethyl-, (E) 106-24-1 Y BASF Chemical Company Results of a Reproduction/ Developmental Toxicity Screening Test in Wistar Rats
8EHQ-0310-17856A (PDF) Nitrogen Containing Heterocycle, Substituted Not provided   BASF Chemical Company Results of an Enhanced One-Generation Reproduction Toxicity Range-Finding Study in Wistar Rats
8EHQ-0310-17857A (PDF) Nitrogen Containing Heterocycle, Substituted Not provided   BASF Chemical Company Results of a Toxicity Study on Green Alga (Pseudokirchneriella subcapitafa)
8EHQ-0310-17858A (PDF) Nitrogen Containing Heterocycle, Substituted Not provided   Confidential Results of an acute toxicity study in Daphnia magna
8EHQ-0310-17859A (PDF) Nitrogen Containing Heterocycle, Substituted Not provided   Confidential Results of an acute toxicity study in Daphnia magna
8EHQ-0310-17860A (PDF) 1,5-naphthylene Diisocyanate (NDI) 3173-72-6   Bayer MaterialScience Results of a 2-Week Inhalation Study in Wistar Rats
8EHQ-0310-17861A (PDF) Not provided Not provided   Confidential Results of two bacterial reverse mutation tests (Ames test)
8EHQ-0310-17863A (PDF) Confidential Not provided   Confidential Results of two acute toxicity study with Daphnia magna and Americamysis bahia
8EHQ-0310-17865A (PDF) Fluorochemical Not provided   Taft Stettinius and Hollister LLP Results of a PFOA study
8EHQ-0310-17867A (PDF) Ethylviolet Not provided   BASF Chemical Company Results of a Repeated Dose 28-Day Oral Toxicity Study in Wistar Rats
8EHQ-0310-17868A (PDF) 2,2'-(methylimino)diethanol 105-59-9 Y BASF Chemical Company Results of a ReproductionIDevelopmental Toxicity Screening Test in Wistar Rats
8EHQ-0310-17869A (PDF) Nitrilotriacetonitrile 7327-60-8 Y AkzoNobel Un-audited results of an OECD 422 (Combined Repeated-dose with Reproductive/Developmental Toxicity) Study
8EHQ-0310-17870A (PDF) 20-30% Water 7732-18-5 N Confidential Results of an acute oral toxicity study in rats
70-90% Dimethylsulfoxide 67-68-5 Y
1-5% Hydroxylamine 7803-49-8  
Tetramethylammonium hydroxide 75-59-2 Y
8EHQ-0310-17873A (PDF) Amines, C 12-14-alkyl, isooctyl phosphates 68187-67-7   Rhodia Inc Results of an acute oral toxicity study in rats
8EHQ-0310-17874A (PDF) MTDlD 20871 Not provided   3M Center Results of a Local Lymph Node Assay in Mice
8EHQ-0310-17875A (PDF) Perfluoroalkyl alkyl ketone Not provided   3M Center Results of an acute oral toxicity study in rats
8EHQ-0310-17876A (PDF) Diphenylguanidine 102-06-7 Y DuPont Haskell Global Centers Results of an acute oral toxicity study in rats and a skin irritation study in guinea pigs
8EHQ-0310-17852A (PDF) Propanoic acid, pentyl ester 624-54-4   Dow Chemical Company Results of a repeated-dose toxicity study in rats
8EHQ-0310-00373DK (PDF) Fluorochemicals Not provided   3M Environmental, Health and Safety Operations Results of a PFOA study
8EHQ-0310-04198B (PDF) 1-Propene, 1 ,l,2,3,3,3hexafluoro 116-15-4 Y DuPont Haskell Global Centers Results of a modeled 48-hour EC50 in Daphnia magna (ECOSAR) and a 96hour EC50 in green algae (ECOSAR)
8EHQ-0310-12263B (PDF) Not provided Not provided   DuPont Haskell Global Centers Results of a biodegradation test
8EHQ-0310-15945Z (PDF) Anthranilamide, substituted Not provided   DuPont Haskell Global Centers Results from an acute toxicity test to Daphnia magna
8EHQ-0310-16436L (PDF) Perfluorinated aliphatic carboxylic acid, ammonium salt Not provided   DuPont Haskell Global Centers Results of an inherent biodegradation test
8EHQ-0310-16436M (PDF) Perfluorinated aliphatic carboxylic acid, ammonium salt Not provided   DuPont Haskell Global Centers Results of a pilot reproduction study in northern bobwhite quail
8EHQ-0310-16478L (PDF) Perfluorinated aliphatic carboxylic acid, ammonium salt Not provided   DuPont Haskell Global Centers Results of an inherent biodegradation test
8EHQ-0310-17187C (PDF) Triethoxyoctylsilane 2943-75-1 Y Silicones Environmental, Health and Safety Council Results of a Combined Repreated Dose Toxicity Study with the Reproductive/Developmental Toxicity Test
8EHQ-0310-17313J (PDF) Methyl (E)-a(methoxymethylene)-2-[[[6(trifluoromethyl)-2pyridinyl]oxy]methyl]benzeneacetate; Picoxystrobin *2 117428-22-5 N DuPont Haskell Global Centers Results of a subchronic dietary neurotoxicity study in rats
8EHQ-0310-17313K (PDF) Methyl (E)-a(methoxymethylene)-2-[[[6(trifluoromethyl)-2pyridinyl]oxy]methyl]benzeneacetate 117428-22-5 N DuPont Haskell Global Centers Observations noted during a pharmacokinetic study in rats
8EHQ-0310-17763C (PDF) Methyl 2-[[[[[4-ethoxy-6(methylamino)-1,3,5triazin-2yl]amino]carbonyl]amino]s ulfonyl]benzoate 97780-06-8 N DuPont Haskell Global Centers Supplemental results of an aquatic toxicity study with Daphnia magna
8EHQ-0310-17798B (PDF) Perfluorooxyalkanoic Acid Salt Not provided   Confidential Results of an oral subacute toxicity study in mice
8EHQ-0310-17798C (PDF) Perfluorooxyalkanoic Acid Salt Not provided   Confidential Results of an oral subacute toxicity study in rats
FYI-0310-01623A (PDF) MTDID 10359 Not provided   3M Center A Preliminary 2-Week Inhalation Toxicity Study in CD Rats
FYI-0310-01625A (PDF) Perfluorooctanoate(PFOA) Not provided   Taft Stettinius and Hollister LLP Results of a PFOA study

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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