8(e) and FYI Submissions Received May 2010

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8EHQ#	CHEM NAME(S)	CAS NO.(S)	USHV	SUBMITTER	DESCRIPTION
8EHQ-0510-15945AA (PDF)	3-Bromo-l-(3-chloro-2pyridinyl)-N-[4-cyano-2methyl-6[(methylamino)carbonyl]phenyl]-1 H-pyrazole-5carboxamide	Not Provided		DuPont Haskell Global Centers	Results of an acute toxicity study to algae with an R&D proprietary mixture containing 3-Bromo-l-(3-chloro-2-pyridinyl)-N-[4cyano-2-methyl6[(methylamino)carbonyl]phenyl]-1 Hpyrazole-5-carboxamide
8EHQ-0510-17930A (PDF)	2-[[(4-amino-6-ethoxyI,3,5-triazin-2yl)aminocarbonyl]aminosul fonyl]-, methyl ester	Not Provided		Dupont	Results of an aquatic plant study with Benzoic acid, 2-[[(4-amino-6-ethoxyI,3,5-triazin-2yl)aminocarbonyl]aminosulfonyl]-, methyl ester
8EHQ-0510-17932A (PDF)	Substituted Tetrahydronapthalene	Confidential		Syngenta Crop Protection, Inc.	Acute Inhalation Study in the Rat with [ CBI chemical], a substituted tetrahydronapthalene,.
8EHQ-0510-17933A (PDF)	Confidential	Confidential		Syngenta Crop Protection, Inc.	Results of a 14-day preliminary dietary toxicity study in mice with [CBI chemical ], a Substituted Benzamide, First Submission.
8EHQ-0510-17934A (PDF)	1-[2(carboxymethoxy)ethyl]-1(carboxymethyl)-4,5dihydro-2-norcoco alkyl, hydroxides, sodium salts	68650-39-5		Rhodia	Evaluation of the ability of alkylamidoamine glycinate (1-[2(carboxymethoxy)ethyl]-1(carboxymethyl)-4,5-dihydro-2norcoco alkyl, hydroxides, sodium salts CASRN 68650-39-5) Majority in C12 & 14 (Amphoacetate) to induce chromosome aberrations in cultured peripheral human lymphocytes.
8EHQ-0510-17935A (PDF)	Substituted Nitrogen Containing Heterocycle	Confidential		BASF	Results of a repeated dose range finding study in Wistar Rats [Crl:WI(HAN)] with Substituted Nitrogen Containing Heterocycle The test substance is an experimental pesticide.
8EHQ-0510-17936A (PDF)	Confidential	Confidential		W.R. Grace & Co.	Letter stating that the chemical submitted is confidential
8EHQ-0510-17937A (PDF)	1-[2(carboxymethoxy)ethyl]-1(carboxymethyl)-4,5dihydro-2-norcoco alkyl, hydroxides, sodium salts	68650-39-5		Environ UK Ltd	Evaluation of the ability of alkylamidoamine glycinate (1-[2(carboxymethoxy)ethyl]-1(carboxymethyl)-4,5-dihydro-2norcoco alkyl, hydroxides, sodium salts CASRN 68650-39-5) Majority in C12 & 14 (Amphoacetate) to Induce chromosome aberrations in cultured peripheral human lymphocytes.
8EHQ-0510-17938A (PDF)	2-Amino-6-chloro-4methyl-11H-pyrido[2,1b]quinazolin-11-one	Not Provided		Dupont	Results of an Ames mutagenicity study with 2-Amino-6-chloro-4-methyl-11Hpyrido[2,1-b]quinazolin-11-one.
8EHQ-0510-17939A (PDF)	Substituted Nitrogen Containing Heterocycle	Confidential		Confidential	Results of an acute fish toxicity study with substituted nitrogen containing heterocycle compound.
8EHQ-0510-17940A (PDF)	1,5-Naphthylene Diisocyanate	Not Provided		Bayer Material Science	Results of V79/HPRT - Test in vitro for the detectionof induced forward mutations. With 1,5-naphthylene diisocyanate
8EHQ-0510-17941A (PDF)	Titanium Dioxide and Titanium Tetrachloride	13463-67-7 and 7550-450		Dupont	Preliminary results from an epidemiology study titled "Occupational Exposure�and Mortality Among Workers at Three Titanium Dioxide Plants
8EHQ-0510-17942A (PDF)	Vanadium Tetroxide	12036-73-6		Vanadium Producers & Reclaimers Association	Preliminary results from an acute inhalation study on vanadium tetroxide (V204).
8EHQ-0510-17943A (PDF)	Vanadyl Sulfate	27774-13-6		Vanadium Producers & Reclaimers Association	Preliminary results from an acute inhalation study on vanadyl sulfate (VOS04)(CASRN 27774-13-6).
8EHQ-0510-17944A (PDF)	1,3,5-triazin-2-amine, 4methoxy-6-methyl	1668-54-8		Dupont	Results ofa non-DuPont acute inhalation toxicity test in rats with 1,3,5-triazin-2-amine, 4-methoxy-6methyl (CASRN 1668-54-8).
8EHQ-0510-17945A (PDF)	Diphenylcresylphosphate	26444-49-5		Bayer Material Science	Results of an acute and repeated dose studies to evaluate the neurotoxicity potential of Diphenylcresylphophate (CASRN 26444-49-5) in chickens.
8EHQ-0510-17946A (PDF)	Multiple Chemicals	Not Provided		Confidential	The results of an acute inhalation toxicity study in rats with a mixture containiing aromatic 200 fluid, catechol, alkylbenzenesulfonic acid, ethyleneglycol-phenethylether, shellsol A 150, diethyleneglycolphenethylether, alkylbenzene, sulfuric acid, and sulfur dioxide.
8EHQ-0510-17947A (PDF)	Alkenyl Succinic Anhydride	68784-12-3		BASF	Results of a skin sensitization study (Maximization Test in Guinea Pigs) with Alkenyl Succinic Anhydride (CASRN 68784-12-3).
8EHQ-0510-17948A (PDF)	Alkenyl Succinic Anhydride	68784-12-3		BASF	Preliminary results of a combined repeated-dose toxicity Study with the reproduction developmental toxicity screening test in Wistar Rats with Alkenyl Succinic Anhydride (CASRN 68784-12-3).
8EHQ-0510-17949A (PDF)	5-chloro-2-(2,4-dichlorophenoxy)-aniline	56966-52-0		BASF	Results of a screening test on acute toxicity in Algae (Desmodesmus subspicatus) with 5-chloro-2-(2,4dichloro-phenoxy)-aniline (CASRN 56966-52-0).
8EHQ-0510-17950A (PDF)	Benzoic acid, 2[(isocyanato)sulfonyl]methyl ester	74222-95-0		Dupont	Results of a dermal irritation study in rabbits with Benzoic acid, 2[(isocyanato)sulfonyl]-methyl ester (CASRN 74222-95-0).
8EHQ-0510-17951A (PDF)	ZMAT number 4054114	Not Provided		Dow Corning	Acute toxicity to the cladoceran (Daphnia magna) under static test conditions using ZMAT number 4054114.
8EHQ-0510-17952A (PDF)	Octamethyltrisiloxane	107-51-7		Silicones Environmental Health and safety Council (SEHSC)	28-Day oral (Gavage) toxicity study in the Sprague-Dawley Rat with Octamethyltrisiloxane (CASRN 107-51-7).
8EHQ-0510-17953A (PDF)	Melamincyanurat	37640-57-6		BASF	Results of a 7 Day feeding study in Wistar Rats [Crl:WI(HAN)] with Melamincyanurat (CASRN 37640-57-6).
8EHQ-0510-17954A (PDF)	Mixture of Chlorcyanbenzole and triazole	Not Provided		BASF	Results of an acute toxicity study in rainbow trout (Oncorhynchus mykiss) with a Mixture Containing Two Active Ingredients: (1) Chlorcyanbenzole and (2) triazole.
8EHQ-0510-17955A (PDF)	Confidential	Not Provided		BASF	Results of acute toxicity screening tests in fathead minnow (Pimephales promelas) with Substituted Nitrogen Containing Heterocycle (SUBSTANCE A), (SUBSTANCE B) and (SUBSTANCE C).
8EHQ-0510-17956A (PDF)	Substituted Nitrogen Containing Heterocycle and�Substituted Thiophene	Not Provided		BASF	Results of acute toxicity screening tests in Daphnia (Daphnia magna) with Substituted Nitrogen Containing Heterocycle (Substance 1) and Substituted Thiophene (Substance 2).
8EHQ-0510-17957A (PDF)	Confidential	Confidential		Confidential	Results of two acute oral toxicity studies with rats; a preliminary developmental toxicity study with rats; a micronucleus study with rats; an acute inhalation study with rats; a micronucleus study in rats; a 2-week oral toxicity study inrats; and an unscheduled DNA Synthesis (UDS) study in rats.
8EHQ-0510-17958A (PDF)	Confidential	Confidential		Confidential	Results of two acute oral toxicity studies with rats; a preliminary developmental toxicity study with rats; a micronucleus study with rats; an acute inhalation study with rats; a micronucleus study in rats; a 2-week oral toxicity study inrats; and an unscheduled DNA Synthesis (UDS) study in rats.
8EHQ-0510-17959A (PDF)	Hexamethylcyclotrisiloxane and Hexamethyldisiloxane	541-05-9 and 107-46-0		Dow Corning	A 28-Day sub-chronic oral gavage feasibility study of various low molecular weight silicone oligomers in Rats.
8EHQ-0510-17960A (PDF)	PFOA/PFOS	Not Provided		Taft Stettinius & Hollister LLP	Report on emerging contaminants of PFOA/PFOS in Cape cod drinking water.
8EHQ-0510-17961A (PDF)	Chloromethyl bis (4fluorophenyl) methylsilane	85491-26-5		Dupont	Results ofa biodegradation study, an acute algal study and a chronic Daphnia magna study with Chloromethyl bis (4-fluorophenyl) methylsilane (CASRN 85491-26-5).
FYI-0510-01627A (PDF)	PFOA/PFOS	Not Provided		Taft Stettinius &Hollister LLP	Report on emerging contaminants in Cape cod drinking water.
8EHQ-0510-00373DM (PDF)	PFOA	Not Provided		3M Environmental Health Safety Operations	2009 Annual report on method development for PFOA generation testing.
8EHQ-0510-12263C (PDF)	Pentane, 1,1,1,2,2,3,4,5,5,5decafluoro	138495-42-8		Dupont	Results of two aquatic toxicity studies with the test substance Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro (CASRN 138495-42-8).
8EHQ-0510-15580C (PDF)	2-Amino-2-methyl-1propanol hydrochloride	3207-12-3		Dow Chemical Company	Follow-up on a reproductive developmental study in rats using 2-Amino-2-methyl-1-propanol hydrochloride; CASRN 3207-12-3.
8EHQ-0510-15945AB (PDF)	3-Bromo-l-(3-chloro-2pyridinyl)-N-[4-cyano-2methyl-6[(methylamino)carbonyl ]phenyl]-IH-pyrazole- 5carboxamide	736994-63-1		Dupont	Final results of a one-year dog study with 3-Bromo-l-(3-chloro-2-pyridinyl)N-[4-cyano-2-methyl-6[(methylamino)carbonyl]phenyl]-IHpyrazole- 5-carboxamide (CASRN 736994-63-1).
8EHQ-0510-16985E (PDF)	4-Pyrimidinecarboxylic acid, 6-amino-5-chloro-2cyclopropyl	858956-08-8		Dupont	Results of an acute toxicity study in rats and mice with 4Pyrimidinecarboxylic acid, 6-amino-5chloro-2-cyclopropyl (CASRN 858956-08-8)
8EHQ-0510-17258B (PDF)	Fluorocarbon	Not Provided		Confidential	Results of an acute inhalation study in rats with Fluorocarbon.
8EHQ-0510-17326B (PDF)	Anionic Surfactant	Not Provided		Confidential	Results of an inherent biodegradation test with Anionic Surfactant.
8EHQ-0510-17356B (PDF)	Dimethylsilanediol	1066-42-8		Dow Corning	An acute oral gavage study in mice to determine the Maximum Tolerated Dose and Systemic Availability using Dimethylsilanediol (CASRN 1066-42-8).
8EHQ-0510-17466B (PDF)	BURA, Asphalt,oxidized	64742-93-4		Asphalt Institute	Summary reporting supplemental information on findings from a mouse skin carcinogenicity evaluation using (BURA) (CASRN: 64742-93-4) fume condensate sample (referred to as "TRA").
8EHQ-0510-17763F (PDF)	Methyl 2-[[[[[4-ethoxy-6(methylamino)-1,3,5triazin2yl]amino]carbonyl]amino ]sulfonyl]benzoate	97780-06-8		Dupont	Results of an aquatic toxicity study with an R&D proprietary mixture containing Methyl 2-[[[[[4-ethoxy-6(methylamino)-1,3,5-triazin2yl]amino]carbonyl]amino ]sulfonyl]benzoate (CASRN 97780-06-8).
8EHQ-0510-17781B (PDF)	1,6bis(trimethoxysilyl)hexane	87135-01-1		Dow Corning	Results of a combined repeated dose toxicity study and a reproductive developmental toxicity Screening Test using 1,6-bis(trimethoxysilyl)hexane (CASRN 87135-01-1) in Sprague-Dawley Rats Via Oral Gavage.
8EHQ-0510-17782B (PDF)	Methyltrimethoxysilane	1185-55-3		Dow Corning	Results of a contact hypersensitivity study in Albino guinea Pigs, Buehler Test using methyltrimethoxysilane (CASRN 1185-55-3).
8EHQ-0510-17848B (PDF)	Fluorocarbon	Not Provided		Confidential	Results of an acute inhalation study in rats with fluorocarbon.
8EHQ-0510-17848C (PDF)	Methyl 2-[[[[[4-ethoxy-6(methylamino)-1,3,5triazin2yl]amino]carbonyl]amino ]sulfonyl]benzoate	97780-06-8		Dupont	Results of two aquatic toxicity studies with Methyl 2-[[[[[4-ethoxy-6(methylamino)-1,3,5-triazin2yl]amino]carbonyl]amino ]sulfonyl]benzoate (CASRN 97780-06-8).

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.

8(e) and FYI Submissions Received May 2010

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