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Section 8(e) Substantial Risk Notifications and FYI Submissions Received March 2011

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0311-18274A (PDF) Confidential *2 CBI   Confidential Results of a 90-day oral (diet) repeated-dose study in rats
8EHQ-0311-18275A (PDF) SUBSTANCE A *2 CBI   Confidential Results of an oral prenatal developmental toxicity screening study in rats with five test substances
SUBSTANCE B *2 CBI    
SUBSTANCE C *2 CBI    
SUBSTANCE D *2 CBI    
SUBSTANCE E *2 CBI    
8EHQ-0311-18276A (PDF) 3-Hydroxy-N-Phenylaniline  101-18-8 N INDSPEC Chemical Corporation Results from an Acute Toxicity to Water Fleas (Daphnia magna) and results from a 72-hour growth inhibition test using freshwater micro algae Selenastrum capricornutum (Raphidocellus subcapitata)
8EHQ-0311-18277A (PDF) Silver(1+) chloride  7783-90-6 N DuPont Haskell Global Centers for Health and Environmental Centers Results from an acute toxicity study with Silver(1+) chloride in rats
8EHQ-0311-18278A (PDF) Disilver(1 +) carbonate  534-16-7 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute toxicity test with Disilver(1+) carbonate in rats
8EHQ-0311-18279A (PDF) Silver Nitrate  7761-88-8 N DuPont Haskell Global Centers for Health and Environmental Scienes Results for sublethal effects of silver nitrate on early-life stage reproduction on Oncorhynchus mykiss and Salmo trutta (brown trout)
8EHQ-0311-18280A (PDF) Disilver(I)oxide  20667-12-3 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute toxicity study with disilver(I)oxide in rats
8EHQ-0311-18281A (PDF) Disilver( 1+) sulfate  10294-26-5 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute toxicity study with disilver(1+) sulfate in rats
8EHQ-0311-18282A (PDF) n-Butyraldehyde  123-72-8 Y DuPont Haskell Global Centers for Health and Environmental Sciences Determining the acute toxicity of the test substance to Leuciscus idus melanotus (freshwater fish) in static freshwater
8EHQ-0311-18283A (PDF) ETHENE, 1, 1,2,2-TETRAFLUORO-,
OXIDIZED, POLYMD., REDUCED, ME ESTERS, REDUCED, 
88645-29-8 N Solvay Solexis, Inc. Results of two four-week oral toxicity studies in rats
8EHQ-0311-18284A (PDF) Amyl Salicylate (Benzoic acid, 2-hydroxy-, pentyl ester). *1,*3 2050-08-0 Y International Flavors & Fragrances Inc. Results for an (acute) algal growth inhibition test
8EHQ-0311-18285A (PDF) 1,2,3,4-Tetrahydroisoquinoline  91-21-4 N BASF Results of intraperitoneal studies with 1,2,3,4-tetrahydroisoquinoline in rats and mice
8EHQ-0311-18286A (PDF) Alcoguard® 5240 *1 Not provided   Akzo Nobel Surface Chemistry LLC Preliminary results from a subchronic oral toxicity study on dose range-finding study on Alcoguard® 5240 dispersant, PMN P-08-0411
8EHQ-0311-18287A (PDF) 3-amino-4-hydroxy-N-[3-(1-methylethoxy) propyl]-hydrochloride (1:1)  114565-70-7 N BASF Results of an Acute Eye Irritation Study in rabbits
8EHQ-0311-18288A (PDF) alpha-(2,4-disubstituted phenyl)-5-(2,6-disubstituted phenyl)-1,3-dialkyl-1H-heteromonocycle-4-methanol  Not provided   Confidential Results of an in vivo micronucleus study in rats
8EHQ-0311-18289A (PDF) Di-tert-Bu polysulfides  68937-96-2 Y Arkema Inc Results of two repeated oral studies with di-tert-bu polysulfides in rats
8EHQ-0311-18290A (PDF) Platinum malonate [PtIV (malonato)3]2- along with [PtIV(malonato)2(OH)2]2- in molecular and/or smaller polymeric species  None   Confidential Summary of a report on the assessment of the allergenic potential of platinum malonate via cytokine fingerprinting and the mouse IgE test.
8EHQ-0311-18291A (PDF) Confidential *2 CBI   Confidential Results of a dietary prenatal developmental toxicity screening study in rats
8EHQ-0311-18292A (PDF) Substance B *2 CBI   Confidential Results of a prenatal developmental toxicity screening study in rats with Substances A, B, C, and D.
Substance A *2 CBI  
Substance C *2 CBI  
Substance D *2 CBI  
8EHQ-0311-18293A (PDF) Substance A *2 CBI   Confidential Results of a repeated-dose range-finding study in rats with Substance A and Substance B.
Substance B *2 CBI  
8EHQ-0311-18294A (PDF) Confidential *2 CBI   Confidential Results of a prenatal developmental toxicity screening study in rats
8EHQ-0311-18295A (PDF) Confidential *2 CBI   Confidential Results of a prenatal developmental toxicity screening study in rats
8EHQ-0311-18296A (PDF) Confidential *2 CBI   Confidential Results of an Acute Toxicity Study in Honeybee (Apis mellifera)
8EHQ-0311-18299A (PDF) Substituted pyrazole *2 CBI   Syngenta Crop Protection, LLC Findings from a 15-month dietary toxicity study in rats and a 28-day dietary mode of action study in rats
8EHQ-0311-18300A (PDF) Substituted benzamide *2 CBI   Syngenta Crop Protection, LLC Results of a maximum tolerated dose study in dogs and a 14-day oral dose tolerability study in rats
8EHQ-0311-18301A (PDF) Benzene *2 71-43-2 Y Dow Chemical Company Results of a pooled study involving three case-control studies on leukemia and benzene exposure in the petroleum industry
8EHQ-0311-18305A (PDF) Fluorinated derivative  CBI   3M Company Preliminary results of an acute inhalation toxicity study in rats
8EHQ-0311-18312A (PDF) Distillates (petroleum), light hydrocracked  64741-77-1 Y American Petroleum Institute (API) Results from an algal growth inhibition test using water accommodated fractions
8EHQ-0311-01324D (PDF) Aliphatic hydrocarbon solvent  Not provided   CBI Declassification of an aliphatic hydrocarbon solvent
8EHQ-0311-01796C (PDF) Polyethoxylated primary amine (C8-C1 8) with an average of
2-20 moles of ethylene oxide *3
61791-26-2 N CBI Declassification of a surfactant mixture
Alpha (p.nonylphenyl) omega-hydroxy poly(oxyethylene) *3 9016-45-9 Y
Ethyleneglycolmono-n-butylether *3 111-76-2 Y
8EHQ-0311-01844B (PDF)  Acrylamide polymer  Not provided   Cyanamid Declassification of an acrylamide polymer
8EHQ-0311-02354B (PDF) Amocool HD Soluble Oil  Not provided   Amoco Corporation Declassification of Amocool HD Soluble Oil
8EHQ-0311-06341B (PDF) P1082  Not provided   Procter & Gamble Company Declassification of information previously claimed as CBI in submission 8EHQ-0892-6341 (EPA DCN 88920004987)
8EHQ-0311-06342B (PDF) B1462.01  Not provided   Procter & Gamble Company Declassification of information previously claimed as CBI in submission 8EHQ-0892-6342 (EPA DCN 88920004988)
8EHQ-0311-06343B (PDF) P1105  Not provided   Procter & Gamble Company Declassification of information previously claimed as CBI in submission 8EHQ-0892-6343 (EPA DCN 88920004989)
8EHQ-0311-06345B (PDF) P1105  Not provided   Procter & Gamble Company Declassification of information previously claimed as CBI in submission 8EHQ-0892-6345 (EPA DCN 88920004991) of the test substance composition.
8EHQ-0311-06351B (PDF) P1165  Not provided   Procter & Gamble Company Declassification of the test substance
8EHQ-0311-10079B (PDF) P0924  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-10083B (PDF) P1947  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-10098B (PDF) P1907 mixture  Not provided   Procter and Gamble Declassification of the chemical composition for 8(e) submission 8EHQ-0892-10098A (DCN: 88920008399s)
P1906 mixture  Not provided  
P1472 (mixture)  Not provided   Procter and Gamble Declassification of specific chemical constituents for 8(e) submission 8EHQ-0892-10098A (DCN: 88920008399s)
P1906 (mixture)  Not provided  
P1907 (mixture)  Not provided  
8EHQ-0311-10104B (PDF) P1907 (mixture)  Not provided   Procter and Gamble Declassification of chemical composition for 8(e) submission 8EHQ-0890-10104A (DCN: 88-920008405s)
P1906 (mixture)  Not provided  
P1472 (mixture)  Not provided  
P1928 (mixture)  Not provided  
8EHQ-0311-10104C (PDF) P1906 (mixture)  Not provided   Procter & Gamble Company Declassification of the specific chemical constituents for 8(e) submission 8EHQ-0892-10104A (DCN: 88920008405s)
P1472 (mixture)  Not provided  
P1907 (mixture)  Not provided  
P1928 (mixture)  Not provided  
8EHQ-0311-10109C (PDF) KO216.01  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-10112B (PDF) B0723-01  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-10141B (PDF) B0429-01  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-10177B (PDF) B0447-01  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-10394B (PDF) B7188  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-11203B (PDF) B7191  Not provided   Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-12031B (PDF) Octyl phenol ethoxylate (mixture)  Confidential   Rohm and Haas Company Declassification of the test substance composition for 8(e) submission 8EHQ-1092-12031A (DCN: 88920010273s)
8EHQ-0311-12730B (PDF) Alcohol Ethoxylate Mixture A  Not provided   Procter & Gamble Company Declassification of the test substance.
Alcohol Ethoxylate Mixture B  Not provided  
8EHQ-0311-12813B (PDF) Alcohol Ethoxylate Mixture  Not provided   The Procter & Gamble Company Declassification of the test substance.
8EHQ-0311-12887B (PDF) Alcohol ethoxylate mixture  Multiple   The Procter & Gamble Company Declassification of the chemical identity originally claimed as CBI in submission 8EHQ-0294-12887A (DCN: 88940000129s)
8EHQ-0311-12918B (PDF) Reaction product of L-Aspartic acid (CAS# 56-84-8); Ethane, 1,2-dibromo- (CAS# 106-93-4); Hydrochloric acid (CAS# 7647-01-0); and Sodium hydroxide (CAS# 1310-73-2)  Not Provided   Procter and Gamble Company Declassification of the test substance identity previously claimed as CBI in submission 8EHQ-94-12918 (EPA DCN 88940000160)
8EHQ-0311-13042C (PDF) Stripper II  Not provided   3M Company Original copy of DCN 88940000284, 8EHQ-94-13042 has been declassified per submitter's request via letter dated 1/13/2011 (DCN 89110000077).  Declassification occurred on 3/03/2011 under direction of EPA attorney advisor Scott Sherlock.
Stripper I  Not provided  
8EHQ-0311-13047B (PDF) Petroleum distillate *3 64742-47-8 Y Cytec Industries, Inc Declassification of information previously claimed as CBI in submission 8EHQ-0594-13047 (EPA DCN 88940000289s)
8EHQ-0311-13181B (PDF) Mixtore of arylalkyl amimonium chlorides  Multiple   Not Provided Declassification of test substance composition previously claimed as CBI in submission 8EHQ-92-13181
8EHQ-0311-13201B (PDF) Mixture  Not provided   CBI Declassification of the test substance composition for 8(e) submission 8EHQ-1092-13201A (DCN: 88920011004s)
8EHQ-0311-13387B (PDF) K0316.01  Not provided   Procter & Gamble Company Declassification of information previously claimed as CBI in submission 8EHQ-0892-13387 (EPA DCN 88920011007).
8EHQ-0311-13613B (PDF) Wacker silicone oil emulsion  Mulitple   Wacker Chemical Corporation Declassification of the chemical identity originally claimed as CBI in submission 8EHQ-0496-13613A (DCN: 88960000093s)
8EHQ-0311-14684C (PDF) (RS)-3-allyl-2-methyl-2-4-oxocyclopent-2-enyl 2,2,3,3- tetramethylcyclopropanecarboxylate *1,*3 64742-47-8 Y Confidential Declassification of a synthetic pyrethroid insecticide
8EHQ-0311-15945AE (PDF) 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide  736994-63-1 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a two generation reproductive toxicity study with 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide (CAS No. 736994-63-1)
8EHQ-0311-16291B (PDF) Benzoic acid, 2-[[[[N- (4-methoxy-6-methyl-1 ,3,5-triazin-2-yl)-methylamine]-carbonyl] amino] sulfonyl] -, methyl ester  101200-48-0 N DuPont Legal Declassification of the test substance.
Propanoic acid, 2-(4-chloro-2-methylphenoxy)-  93-65-2 N
8EHQ-0311-16409B (PDF) TRIMETHYLINDAN-1-ONE *1 54440-17-4 N Givaudan Fragrances Corporation Declassification of information previously claimed as CBI in submission 8EJQ-0311-16409B (EPA DCN 89110000176)
8EHQ-0311-16439B (PDF) p-Nitrobenzyl tosylate  4450-68-4 N McKenna Long & Aldridge Declassification of p-Nitrobenzyl tosylate
8EHQ-0311-16533C (PDF) 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro- *1 1763-23-1 N JSR Micro, Inc. Declassification of CASRN 939-23-1, 1763-23-1, and 66003-78-9
Pyridine,4-phenyl-  939-23-1 N
Sulfonium, triphenyl-, salt with trifluoromethanesulfonic acid *1 66003-78-9 N
8EHQ-0311-16750C (PDF) Aqueous solution of Epichlorohydrin-Dimethylamine Copolymer  25988-97-0 N Nalco Company Declassification of Aqueous solution of Epichlorohydrin - Dimethylamine Copolymer
8EHQ-0311-16807B (PDF) Imidodicarbonimidic diamide, N-(2-methyl-phenyl)-  93-69-6 N DuPont Legal Declassification of the test substance.
8EHQ-0311-16913H (PDF) 1-Octanol, 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-  647-42-7 N DuPont Legal Declassification of the test substance.
8EHQ-0311-16995B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-16996B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17027B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17045F (PDF) Perfluorinated Aliphatic Carboxylic Acid  Not provided   DuPont Legal Declassification of the test substance.
8EHQ-0311-17081B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17198C (PDF) Benzeneacetonitrile, alpha-cyclohexylidene-  10461-98-0 N Givaudan Fragrances Corporation Declassification of information previously claimed as CBI in submission 8EHQ-0311-17198C (EPA DCN 89110000177)
8EHQ-0311-17209B (PDF) CBI *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17297B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17353C (PDF) Oxirane,2-[(bicyclo[2.2.1]hept-5-en-2-ylmethoxy)methyl]- 3188-75-8 N SafePharm Laboratories Declassification of Oxirane,2-[(bicyclo[2.2.1]hept-5-en-2-ylmethoxy)methyl]-
8EHQ-0311-17484B (PDF) 4-(1,1-Dimethylethyl) benzenepropanal)  18127-01-0 N Givaudan Fragrances Corporation Declassification of the chemical identity previously claimed as CBI in 8(e) submission 8EHQ-0409-17484A (DCN: 88090000208s)
8EHQ-0311-17511B (PDF) Benzenepropanol, alpha-methyl-4-(1-methylethyl)-  103-95-7 N Givaudan Fragrances Corporation Declassification of the chemical identity originally claimed as CBI in 8(e) submission 8EHQ-0509-17511A (DCN: 88090000235s)
8EHQ-0311-17549B (PDF)  Phosphoric acid, P,P'-1,3-phenylene P,P,P',P'-tetrakis(2,6-dimethylphenyl) ester  139189-30-3 N Japan Technical Information Center, Inc. Declassification of CASRN 139189-30-3
8EHQ-0311-17682B (PDF) Oxirane,2-[(bicyclo[2.2.1]hept-5-en-2-ylmethoxy)methyl]-  3188-75-8 N Confidential Declassification of epoxide substituted bicyclic olefin
8EHQ-0311-17866B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17907B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17957B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-17958B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-18077B (PDF) Multi-walled carbon nanotube  Not Provided   Ropes & Gray LLP Supplemental Filing for Notice 8EHQ-10-18077A
8EHQ-0311-18107B (PDF) Dimethyl, methyhydrogen siloxane with polypropylene glycol  1043538-34-6 N Dow Corning Corporation Dermal Sensitization Test in Guinea Pigs with mixture containing isodecyl neopentanoate (CAS No. 60209-82-7) and dimethyl, methyhydrogen siloxane with polypropylene glycol (CAS No. 1043538-34-6)
Isodecyl Neopentanoate  60209-82-7 N
8EHQ-0311-18166B (PDF) Confidential *2 CBI   Confidential Findings from two acute oral toxicity studies in rats with the cis and trans isomers.
8EHQ-0311-18198B (PDF) 4-Mercaptomethyl-3,6-dithia-1,8-octanedithiol *1 131538-00-6 N Center for Regulatory Services, Inc. Declassification of test substance identification
8EHQ-0311-18206B (PDF) Methyl tertiary-butyl ether  1634-04-4 Y Shell Companies Final report of the 2-year chronic toxicity/carcinogenicity study which was the subject of 8(e) submission 8EHQ-1210-18206A (88110000090)
8EHQ-0311-18233B (PDF) Iron, isomerized tartarate sodium complexes  Not provided   AkzoNobel Results of an un-audited microscopic 90-day/ reproduction/development screening in rats





(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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