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Section 8(e) Substantial Risk Notifications and FYI Submissions Received December 2012

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8EHQ/FYI#
Chemical Name
CASRN
Submitter
Submission Description
8EHQ-1212-18906A (PDF) Confidential Not provided Confidential Results of a bioconcentration study in Zebrafish
8EHQ-1212-18907A (PDF) Confidential *2 Not provided Confidential Results of a bioconcentration study in Zebrafish
8EHQ-1212-18908A (PDF) Confidential *2 Not provided Confidential Results of a bioconcentration study in Zebrafish
8EHQ-1212-18917A (PDF) Confidential *2 Confidential Confidential Results of a prenatal developmental toxicity study in wistar rats with an experimental pesticide
8EHQ-1212-18918A (PDF) Confidential Confidential Confidential Results of a micronucleus screening test in vivo performed on the basis of OECD 474 (Mammalian Erythrocyte Micronucleus test with test substance LS 5869752
8EHQ-1212-18919A (PDF) Confidential Confidental Confidential Results of a Bovine Corneal Opacity and Permeability Test (BOOP Test) with an experimental solvent.
8EHQ-1212-18920A (PDF) (4-nonylphenoxy) acetic acid 3115-49-9 BASF Results of an acute toxicity study in Daphnia magna with (4-nonyiphenoxy) acetic acid (CASRN 3115-48-8)
8EHQ-1212-18921A (PDF) 2-chloro-N-(pyrazol-1-ylmethyl)acet-2',6'-xylidide *2 67129-08-2 BASF Results of the effects of BAS 479 (Metazachlor), 2-chloro-N-(pyrazol-1-ylmethyl)acet-2',6'-xylidide, (CASRN 67129-08-2) on the Growth of the aquatic plant Glyceria maxima
8EHQ-1212-18923A (PDF) n-oleyl-1 ,3-propylenediamine 7173-62-8 Arkema Results of a 21-day Daphnia survival and reproduction study using n-oleyl-1,3-propylenediamine (CASRN 71 73-62-8)
8EHQ-1212-18924A (PDF) n-tallow alkyltrimethylenedi-propane-1,3-diamine 61791-55-7 Arkema Results of a 72-hour algal growth inhibition study using n-tallow alkyltrimethylenedi-propane-1,3-diamine (CASRN 61791-55-7)
8EHQ-1212-18925A (PDF) 2,3-Dimethyl-2,3-diphenylbutane 1889-67-4 United Initiators Results for a Local Lymph Node Assay (LLNA) in mice with 2,3-Dimethyl-2,3-diphenylbutane (CCDFB) (CASRN 1889-67-4)
8EHQ-1212-18926A (PDF) 2,3-Dimethyl-2,3-diphenylbutane 1889-67-4 United Initiators Results for a combined repeated dose toxicity study with the reproduction/ developmental Toxicity Screening Test on male and female rats with 2,3-Dimethyl-2,3-diphenylbutane CCDFB-90 (CASRN 1889-67-4)
8EHQ-1212-18927A (PDF) perfluorooctanoate acid  Not Provided Taft Stettinius and Hollister LLP Probable link evaluation for heart disease (including high blood pressure, high cholesterol, coronary artery disease) after to exposure to perfluorooctanoate acid ("PFOA," a/k/a "C-8.
8EHQ-1212-18928A (PDF) 2,3-dihydro-1,1-dimethyl- 300371-33-9 Firmenich Inc. Results from a Oral (Gavage) 28-day Oral Toxicity Study (OECD Guideline 407) test with 1H-indene-ar-propanal, 2,3-dihydro-1,1-dimethyl- (9CI) (CASRN 300371-33-9) in Rats
8EHQ-1212-18929A (PDF) Allyl Alcohol 107-18-6 Lyondelbasell Allyl Alcohol (CASRN 107-18-6) Dose Range Finding Developmental Screening Assay with New Zealand White Rabbits
8EHQ-1212-18930A (PDF) N-((2-Hydroxy-5-nonylphenyl)methyl)-N-methylglycine sodium salt (1:1) 56968-08-2 Dow Chemical Company The results of a freshwater green algal (Pseudokirchneriella subcapitata) test with N-((2-Hydroxy-5-nonylphenyl)methyl)-N-methylglycine sodium salt (1:1) CASRN 56968-08-2
8EHQ-1212-18931A (PDF) Phenol, 4,4'-(1-methylethylidene)bis-, polymer with 1,3-benzenedimethanamine and
2- (chloromethyl)oxirane
113930-69-1 Dow Chemical Company Results of a 48-hour toxicity study of Daphnia magna with Phenol, 4,4'-(1-methylethylidene)bis-, polymer with 1,3-benzenedimethanamine and
2- (chloromethyl)oxirane CASRN 113930-69-1
8EHQ-1212-18932A (PDF) Substituted Pyridine Confidential Syngenta Crop Protection, LLC The Results of an oral toxicity study in rats with a substituted pyridine (generic name).
8EHQ-1212-18933A (PDF) Confidential Confidential Confidential The results of a skin sensitization study (Buehler test)
8EHQ-1212-18934A (PDF) Confidential *2 Confidential Confidential The results of an acute toxicity study on honey bee (Apis mellifera) with two experimental pesticides
8EHQ-1212-18935A (PDF) Confidential *2 Confidential Confidential The results of an acute toxicity study on honey bee (Apis mellifera) with two experimental pesticides
8EHQ-1212-18936A (PDF) Confidential *2 Confidential Confidential Results of an acute toxicity study on honey bee (Apis mellifera) with two experimental pesticides
8EHQ-1212-18937A (PDF) Confidential *2 Confidential Confidential The results of an acute toxicity study on honey bee (Apis mellifera) with two experimental pesticides
8EHQ-1212-18938A (PDF) C14-18 alpha-olefin epoxide, reaction products with boric acid 84819-41-0 Lubrizol The Sensitization Study by Dermal Administration in Guinea Pigs-Modified Buehler Design (Final Report) on C14-18 alpha-olefin epoxide, reaction products with boric acid (CASRN 84819-41-0)
8EHQ-1212-18940A (PDF) Tosyl chloride 98-59-9 AkzoNobel The results on an OECD 429 LLNA on tosyl chloride (PTSC) CASRN 98-59-9
8EHQ-1212-18941A (PDF) 4,4 Biphenol 92-88-6 Solvay Specialty Polymers Findings from a Local Lymph Node Assay in mice conducted on 4,4 Biphenol (Biphenol), CASRN 92-88-6.
8EHQ-1212-18942A (PDF) 4-t-butylcyclohexyl acetate 32210-23-4 Firmenich Inc. The results from a oral (gavage) 28-day toxicity study (OECD Guideline 407) test in rats with 4-t-butylcyclohexyl acetate (CASRN 32210-23-4)
8EHQ-1212-18943A (PDF) Fluoroalkyl nitro derivative Not Provided Confidential The results from an inhalation toxicity study in rats conducted on fluoroalkyl nitro derivative
8EHQ-1212-18944A (PDF) Fluoroalkyl nitro derivative Not Provided Confidential The results from a four-hour inhalation toxicity study in rats conducted on fluoroalkyl nitrite
8EHQ-1212-18945A (PDF) Fluorinated alkyl nitrile derivative Not Provided Confidential The results from a four-hour inhalation toxicity study in rats conducted on fluorinated alkyl nitrile derivative
8EHQ-1212-18946A (PDF) Confidential Confidential Confidential The results from a GLP acute oral toxicity test and a skin and eye irritation test
8EHQ-1212-18947A (PDF) N4-Amine N,N'-Bis-(3-Aminopropyl)-ethylenediamine 10563-26-5 BASF The results of a combined repeat dose reproduction toxicity screening test (OECD 422) in Wistar Rats with N4-Amine N,N'-Bis-(3-Aminopropyl)-ethylenediamine (CASRN 10563-26-5)
8EHQ-1212-18948A (PDF) Confidential *2 Confidential Confidential The results of a maternal toxicity study in Wistar Rats [Crl:WI(HAN)] with an experimental pesticide.
8EHQ-1212-18949A (PDF) Confidential Confidential Confidential The results of an EpiDerm™ skin corrosion test with an experimental solvent.
8EHQ-1212-18950A (PDF) Confidential *2 Confidential Confidential The results of a repeated-dose test toxicity study in C57BL/6 J Rj mice with an experimental pesticide
8EHQ-1212-18951A (PDF) Confidential *2 Confidential Confidential The results of a repeated-dose test study in C57BL/6 J Rj mice with an experimental pesticide
8EHQ-1212-18952A (PDF) Confidential *2 Confidential Confidential The results of a chronic toxicity test on Collembola (Folsomnia candida), with an experimental pesticide
8EHQ-1212-18953A (PDF) Confidential *2 Confidential Confidential The results of a chronic toxicity test on Collembola (Folsomnia candida), with an experimental pesticide
8EHQ-1212-18954A (PDF) Confidential *2 Confidential Confidential The results of a chronic toxicity study in water flea (Daphnia magna) with an experimental pesticide
FYI-1212-01699A (PDF) N/A N/A Evergreen Biodiesel Production Facility, LLC Notification of a Responsible Signing Official (RCO) Change with in Evergreen Biodiesel Production Facility, LLC.
8EHQ-1212-16973B (PDF) Peroxide, 1,1'-bis(1, 1-dimethylethyl), 110-05-4 AkzoNobel Results from a dose range finding study in rats with Peroxide, 1,1'-bis(1, 1-dimethylethyl), (CASRN 110-05-4).
8EHQ-1212- 16995O (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-16996O (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17027M (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17081M (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17209M (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17297N (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17866M (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17957M (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-17958L (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-18166L (PDF) Confidential Confidential Confidential The results of three toxicity studies
8EHQ-1212-18664B (PDF) Dioxopyrimidium inner salt Not Provided Confidential Results of a chromosome aberration genetic toxicity study with Dioxopyrimidium inner salt.
8EHQ-1212-18679B (PDF) Phosphorodithioic acid, O,O-bis(2-methylpropyl) ester,
compd. with N,N-dimethylmethanamine (1:1)
1354201-99-2 Cytec Assessment of contact hypersenistivity in the mouse (Local Lymph Node Assay with phosphorodithioic acid, O,O-bis(2-methylpropyl) ester, compd. with N,N-dimethylmethanamine (1:1) (CASRN 1354201-99-2)
8EHQ-1212-18783B (PDF) 1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate  22288-43-3 AkzoNobel Results on a draft report for an OECD 422 Combined Repeat Dose, Reproduction/Developmental Toxicity Screening Test with 1,1,3,3-tetramethylbutyl 2-ethylperoxyhexanoate (CASRN 22288-43-3).
8EHQ-1212-18814B (PDF) Confidential *2 Confidential Confidential Additional results of a prenatal developmental toxicity study in Wistar Rats with a developmental pesticide.

*1 =  PMN;  *2  =  Pesticide;  * 3 = Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission.  8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s.  The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A).  The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
 
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters.  Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number.  Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information.  This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

Description - A general description of the type of study or information submitted, but not study results.  A PDF electronic copy of the submission is attached.


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