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Section 8(e) Substantial Risk Notifications and FYI Submissions Received February 2012

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0212-18546A (PDF) Pyridine, substituted *2 Confidential   Syngenta Crop Protection, LLC Results of a dietary developmental neurotoxicity study in rats
8EHQ-0212-18547A (PDF) Octyl-3,5-di-tert-butyl-4-hydroxy-hydrocinnamate *1 125643-61-0 N Songwon International-Americas, Inc. Results of an algal growth inhibition test
8EHQ-0212-18548A (PDF) Dibutylin oxide *3 818-08-6 Y Songwon International-Americas, Inc. Results of an acute eye irritation study in rabbits
8EHQ-0212-18549A (PDF) 4-Amino 3-Nitro Phenyl Ethylsulfone, (IUPAC Name: 4-(ethylsulfonyl)-2-nitro-benzenamine) 23306-60-7 N BASF Corporation Results of 28-day dermal toxicity study in rats and additional results of a combined repeated-dose/reproduction/ developmental toxicity study in rats
8EHQ-0212-18550A (PDF) Confidential *2 Confidential   Confidential Results of an acute toxicity screening study in fish (Pimephales promelas)
8EHQ-0212-18551A (PDF) Substance A *2 Confidential   Confidential Results of an acute toxicity study in chironomus (Chironomus riparius)
Substance B *2 Confidential
8EHQ-0212-18552A (PDF) EC Formulation *2 Confidential   Confidential Results of an acute toxicity study in the honeybee (Apis mellifera)
8EHQ-0212-18553A (PDF) N-(disubstituted-carbomonocycle)-(disubstituted carbomonocycle)-dialkyl-heteromonocycle-amine  None   Confidential Results of a 2-week repeat dose toxicity study in rats
8EHQ-0212-18554A (PDF) Bisisobutyryl peroxide  3437-84-1 N Akzo Nobel Services Inc. Un-audited interim results of an OECD 407 28-day study in rats
8EHQ-0212-18555A (PDF) 2-Propenoic acid, octadecyl ester  4813-57-4 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a skin irritation study in rabbits
8EHQ-0212-18556A (PDF) 1,1,3,3-tetramethylbutyl 2- ethylperoxyhexanoate  22288-43-3 N AkzoNobel Results of a skin sensitization study in mice
8EHQ-0212-18557A (PDF) 4- (ethylsulfonyl)-2-nitro-benzenamine  23306-60-7 N BASF Results of a Repeated Dose 90-Day Oral Toxicity Study in Rats
8EHQ-0212-18558A (PDF) Confidential *2 Confidential   Confidential Results of a 28-day oral repeated-dose study in mice
8EHQ-0212-18559A (PDF) Confidential *2 Confidential   Confidential Results of an Acute Toxicity Study on Honeybee (Apis Mellifera)
8EHQ-0212-18560A (PDF) Substance 5 *2 Confidential   Confidential Results of an Acute Toxicity Study in Water Flea (Daphnia magna)
Substance 1 *2 Confidential
Substance 2 *2 Confidential
Substance 4 *2 Confidential
Substance 3 *2 Confidential
8EHQ-0212-18561A (PDF) 1-Butanethiol  109-79-5 Y Chevron Phillips Results of a skin sensitization potential in mice
8EHQ-0212-18562A (PDF) Catechol  120-80-9 Y Rhodia Results of an in vivo comet assay in rats
8EHQ-0212-18563A (PDF) Partially fluorinated alcohol substituted glycol  Not provided   Confidential Results of an acute oral toxicity study in mice
8EHQ-0212-18564A (PDF) Phosphonium, tributyloctyl-,chloride (1:1)  56315-19-6 N Cytec Industries Inc. Results of a Local Lymph Node Assay (LLNA) and a Freshwater Alga and Cyanobacteria, Growth Inhibition Test.
8EHQ-0212-18565A (PDF) 1-Aminoadamantanhydrochlorid  665-66-7 N BASF Corporation Results of an EpiDerm Skin Corrosion Test
8EHQ-0212-18566A (PDF) 2-Oxiranecarboxylic acid, methyl ester  4538-50-5 N BASF Corporation Results of a Salmonella Typhimurium/ Escheria Coli Reverse Mutation Assay
8EHQ-0212-18567A (PDF) Confidential *2 Confidential   Confidential Interim results of a preliminary prenatal developmental toxicity screening study in rats
8EHQ-0212-18568A (PDF) Substance A *1 Confidential   Confidential Results of an acute oral toxicity study in the honey bee (Apis Mellifera)
Substance B *2 Confidential  
8EHQ-0212-18569A (PDF) Propanoyl Fluoride  430-71-7 N Confidential Results from a four-hour inhalation toxicity study in rats
8EHQ-0212-18570A (PDF) Cobalt Lithium Manganese Nickel Oxide *1 182442-95-1 N BASF Corporation Information on a 5-Day Range Finding Inhalation Study in male Wistar Rats
8EHQ-0212-18571A (PDF) Confidential  Confidential   Confidential Results of OECD 422 Combined Repeated Dose Toxicity Study with the Reproduction/ Developmental Toxicity Screening Test in Wistar Rats
8EHQ-0212-18572A (PDF) Confidential  Confidential   Confidential Results of an acute immobilization test on daphnids and an acute toxicity test on mysid
8EHQ-0212-18573A (PDF) Bisisobutyryl peroxide  3437-84-1 N Akzo Nobel Services Inc. Histopathology results on an OECD 407 28-day study
hydrocarbons, C4, 1, 3-butadiene-free, polymdl., triisobutylene fraction, hydrogenated  93685-81-5 N
8EHQ-0212-18574A (PDF) 1,3,5-Triazine-2,4-diamine, N2,N2-dimethyl-6-(2,2,2-trifluoro-ethoxy)- *1 145963-84-4 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a biodegradation test
8EHQ-0212-18575A (PDF) 2-Pyridinesulfonamide, 3-(ethylsulfonyl)- *1 117671-01-9 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a biodegradation study
8EHQ-0212-18576A (PDF) 1,3,3,3-Tetrafluoropropene  1645-83-6 N Honeywell Preliminary results from a 2-generation reproduction, inhalation toxicity study in rats
8EHQ-0212-18577A (PDF) OO-tertbutyl-O-(2-ethylhexyl) monoperoxycarbonate  34443-12-4 N Arkema Inc. Preliminary results on a mouse lymphoma assay
8EHQ-0212-18583A (PDF) Primaset DT-4000 Not provided   Lonza Inc Preliminary results of a skin sensitization study
8EHQ-0212-18608A (PDF)          
FYI-0212-01688A (PDF) CN-3384A (brominated polyphenyl ether)  Not provided   Chemtura Corporation Results of an audited draft report of a Daphnia magna reproduction test
FYI-0212-01689A (PDF) Confidential  Confidential   Confidential Preliminary findings from a Local Lymph Node Assay (LLNA)
FYI-0212-01690A (PDF) Confidential  Confidential   Confidential Preliminary findings from a Local Lymph Node Assay (LLNA)
FYI-0212-01691A (PDF) Mixture  71551-12-7 and 375-40-6   Halocarbon Products Corporation Results of an acute inhalation test in rats
8EHQ-0212-14235E (PDF) Ethyl 2-(4-phenoxyphenyl)lactate  132584-17-9 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of studies for acute fish embryo toxicity, acute fish toxicity, acute daphnia toxicity, developmental toxicity in rabbits and subchronic oral toxicity in rats
8EHQ-0212-16995K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-16996K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17027K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17081K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17209K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17297K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17365F (PDF) Octanoic acid, 4,4,5,5,6,6,7,7,8,8,8-undecafluoro-  914637-49-3 N DuPont Haskell Global Centers for Health and Environmental Sciences Final results of a 14-day oral toxicity study in rats
8EHQ-0212-17866J (PDF) Confidential *2 Confidential N Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17907J (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17957K (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-17958J (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-18166J (PDF) Confidential *2 Confidential   Confidential Dose range finding study for acute neurotoxicity study in rats
8EHQ-0212-18200B (PDF) di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide  6731-36-8 N Akzo Nobel Services Inc. Results from a daphnia acute immobilization test
8EHQ-0212-18512B (PDF) Hydrofluoroolefin  Confidential   Confidential Results of an acute inhalation study in rats
8EHQ-0212-18516B (PDF) 4-trifluoromethoxybenzenz-N-carboxymethyl carbomoyl chloride *1 173903-15-6 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of two dose range finding studies and a developmental toxicity study in rats

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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