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Section 8(e) Substantial Risk Notifications and FYI Submissions Received January 2012

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8EHQ#
CHEM NAME(S)
CAS NO.(S)
USHV
SUBMITTER
DESCRIPTION
8EHQ-0112-16292C (PDF) 3-{hexyl[(nonafluorobutyl)sulfonyl]amnino }-2-hydroxy-l1-propanesulfonic acid, ammonium salt  606967-06-0 N 3M Center Results of an acute eye irritation study in rabbits
8EHQ-0112-16995J (PDF) Confidential *2 Confidential   Confidential Results of a 13-week neurotoxicity (feeding) study in rats
8EHQ-0112-16996J (PDF) Confidential *2 Confidential   Confidential Results of a 13-week neurotoxicity (feeding) study in rats
8EHQ-0112-17027J (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-17081J (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-17209J (PDF) Confidential *2 Confidential   Confidential Results of a 13 -Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-17297J (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-17397C (PDF) 2-Fluoro-6-(trifluoromethyl)pyridine  94239-04-4 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of two biodegradation studies
8EHQ-0112-17866I (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-17907I (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-17924C (PDF) Confidential  Not provided   Confidential Supplemental Information
8EHQ-0112-17957J (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-18042G (PDF) Methyl 2-[[[[(4,6-dimnethoxy-2-pyrimidinyl)amino]carbonyl]aminolsulfonyl]-6-(trifluoromethyl)-3-pyridinecarboxylate monosodium salt; flupyrsulfuon methyl 144740-54-5 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of a toxicity study in the freshwater vascular plant, Lemna gibba
8EHQ-0112-18166I (PDF) Confidential *2 Confidential   Confidential Results of a 13-Week Neurotoxicity (Feeding) Study in Rats
8EHQ-0112-18425B (PDF) Diiododifluoromethane  1184-76-5 N Confidential Results of a one-hour inhalation toxicity study in rats
8EHQ-0112-18427B (PDF) Confidential *2 Confidential   Confidential Two results of a repeated-dose 28-day oral toxicity study in Wistar rats
8EHQ-0112-18458B (PDF)          
8EHQ-0112-18464B (PDF) Tinuvin 144  63843-89-0 N BASF Corporation Results of a repeated-dose 28-day oral toxicity study in male wistar rats
8EHQ-0112-18505B (PDF) Piccoclastic A5 Hydrocarbon Resin *3 9003-53-6 N Eastman Chemical Company Data tables for previous submission 8EHQ-11-18505
8EHQ-0112-18515A (PDF) Hydrochlorofluorocarbon  Confidential   Confidential Results of an acute inhalation study in rats
8EHQ-0112-18516A (PDF) 4-trifluoromethoxybenzenz-N-carboxymethy carbamoyl chloride  173903-15-6 N DuPont Haskell Global Centers for Health and Environmental Sciences Results of algal and biodegradation studies
8EHQ-0112-18517A (PDF) Butanenitrile, 2,2'-azobis[2-methyl- *1 13472-08-7 Y DuPont Haskell Global Centers for Health and Environmental Sciences Results of an acute toxicity study in Daphnia magna
8EHQ-0112-18518A (PDF) Confidential *2 Confidential   Confidential Results of an enhanced one-generation reproduction toxicity study (range finding) in Wistar rats
8EHQ-0112-18519A (PDF) Substance B *2 Confidential   Confidential Results of an acute toxicity study in honeybees (Apis mellifera)
Substance A *2 Confidential      
8EHQ-0112-18520A (PDF) Confidential *2 Confidential   Confidential Results of an acute toxicity study in honeybees
8EHQ-0112-18521A (PDF) Substance B *2 Confidential   Confidential Results of an acute toxicity study in honeybees (Apis mellifera)
Substance A *2 Confidential      
8EHQ-0112-18522A (PDF) Substance A *2 Not provided   Confidential Results of an acute toxicity study in honeybees
Substance B *2 Not provided      
8EHQ-0112-18523A (PDF) Confidential *2 Confidential   Confidential Results of a micronucleus study in NMRI mice (in vivo)
8EHQ-0112-18524A (PDF) Confidential *2 Confidential   Confidential Results of a prenatal gavage developmental toxicity study in rats
8EHQ-0112-18525A (PDF) Substance B *2 Confidential   Confidential Results of an acute toxicity study in water flea (Daphnia magna)
Substance A *2 Confidential   Confidential Results of an acute toxicity study in water flea (Daphnia magna)
8EHQ-0112-18526A (PDF) Methyl-Diamino-Cyclohexan; Reaction mass of 2-methylcyclohexane-1,3-diamine and 4-methylcyclohexane-1,3-diamine  13897-55-7 and 13897-56-8 N BASF Corporation Results of an OECD 422 combined repeated-dose toxicity study with reproduction/developmental toxicity screening test in rats
8EHQ-0112-18527A (PDF) Acetylmorpholin  1696-20-4 N BASF Corporation Results of a combined repeated-dose toxicity study with a reproduction/ developmental toxicity screening test in rats
8EHQ-0112-18528A (PDF) Confidential  Confidential   W.R. Grace & Co. Certain information which EPA may consider reportable under the Toxics Substance Control Act (TSCA) Section 8(e) (type of study and study detials not specified in sanitized version)
8EHQ-0112-18529A (PDF) Substance 2 *2 Confidential   Confidential Results of an acute toxicity study in the insect chironomus
Substance 3 *2 Confidential      
Substance 4 *2 Confidential      
Substance 1 *2 Confidential      
8EHQ-0112-18530A (PDF) Substance B *2 Confidential   Confidential Results of an acute toxicity study in the insect Chironomus
Substance C *2 Confidential      
Substance D *2 Confidential      
Substance A *2 Confidential      
8EHQ-0112-18531A (PDF) Confidential  Confidential   Confidential Results of a 14-day oral (gavage) range finding study in rats
8EHQ-0112-18532A (PDF) Fluorocarbon  Confidential   Confidential Results of an acute inhalation study in rats
8EHQ-0112-18533A (PDF) Substance 1 *2 Confidential   Confidential Results of an acute toxicity study in the insect Chironomus
Substance 2 *2 Confidential      
8EHQ-0112-18534A (PDF) 1,1,2,3,3-Pentamethyl-6,7-dihydro-4-(5H)-Indanone (CASHMERAN)  33704-61-9 N International Flavors & Fragrances Inc. (IFF) Information on an oral (dietary) reproduction/ developmental toxicity screening test in rats
8EHQ-0112-18535A (PDF) 3-Hepten-2-one, 3,4,5,6,6-pentamethyl-, (Z)- (KOAVONE)  86115-11-9 N International Flavors & Fragrances Inc. (IFF) Information on a combined oral (dietary) repeated-dose toxicity study and reproduction/developmental toxicity screening test in rats
8EHQ-0112-18536A (PDF) tert-Butyl peroxyisobutyrate (TBPIB-75-AL)  109-13-7 N United Initiators, Inc. Results for a HPRT assay test (Mammalian Gene Mutation Test in CHO-K1 cells)
8EHQ-0112-18537A (PDF) Confidential *2 None   Confidential Results of a 1-week oral toxicity study in dogs
8EHQ-0112-18538A (PDF) Multi-walled carbon nanotube *1 Not Provided   Ropes & Gray LLP Results of a 90-day inhalation study in rats
8EHQ-0112-18539A (PDF) Fluorocarbon  Confidential   Confidential Results of an acute inhalation toxicity study in rats
8EHQ-0112-18540A (PDF) Troychem Zinc 8  None   Troy Corporation Submission of adverse effects incident report
8EHQ-0112-18541A (PDF) Formaldehyde, oligomeric reaction products with aniline (oligomeric MDA, PMDA)  25214-70-4 N American Chemistry Council Diisocyanates Panel Results of an acute toxicity study in Daphnia magna
8EHQ-0112-18542A (PDF) Perfluoroisobutyryl fluoride  677-84-9 N 3M Company Findings from an acute inhalation study in rats
8EHQ-0112-18543A (PDF) 3-lodo-1,1,2,3,3-pentafluoropropene; MTDID 29023  431-65-2 N Confidential Results from a one-hour inhalation toxicity study in rats
8EHQ-0112-18544A (PDF) Pentafluoropropionitrile  422-04-8 N Confidential Results from a one-hour inhalation toxicity study in rats
8EHQ-0112-18545A (PDF) Reaction mass of diethylene glycol dibenzoate (DEGDB) and dipropylene glycol dibenzoate (DPGDB) *3 120-55-8 and 27138-31-4 Y Eastman Chemical Company Results of an algal toxicity range-finding test
FYI-0112-01686A (PDF) VINYL CHLORIDE  75-01-4 Y University of Louisville Results of an occupational exposure study
FYI-0112-01687A (PDF) CBI  CBI   Confidential Preliminary data for a Local Lymph Node Assay (LLNA) in mice

(A) PMN; (B) Pesticide; (C) Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A).
Supplemental means that it is a follow-up to an earlier submitted report. Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission. 8EHQ number is a useful reference to request a copy of a submission.FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s. The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A). The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.

NOTE that OPPT routinely sends follow-up requests to 8(e) submitters. Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number. Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information. This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

USHV - High production volume chemical in the U.S., including domestic manufacture and importation. EPA defines high production volume as annual production one million pounds or more pounds.

Description - A general description of the type of study or information submitted, but not study results. A PDF electronic copy of the submission is attached.


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