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Section 8(e) Substantial Risk Notifications and FYI Submissions Received October 2012

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8EHQ/FYI#
Chemical Name
CASRN
Submitter
Submission Description
8EHQ-1012-18837A (PDF) Confidential *2 Not provided Confidential Results of a prenatal developmental toxicity study in New Zealand White rabbits
8EHQ-1012-18841A (PDF) Acetic acid, [(5-chloro-8-quinolinyl)oxy]-, 1-methyhexyl ester *1 99607-70-2 Syngenta Crop Protection, LLC Information concerning a manufacturing impurity that was recently discovered from an impurity analysis
8EHQ-1012-18843A (PDF) Fatty acids, C18-unsatd., trimers, compds. with oleylamine *1 147900-93-4 BASF Corporation Results of a local lymph node assay in mice
Fatty acids, tall-oil, compds. with oleylamine *1 85711-55-3
8EHQ-1012-18844A (PDF) Confidential *2 Confidential Confidential Results of a range-finding gavage study in female, non-pregnant New Zealand white rabbits
8EHQ-1012-18845A (PDF) Confidential *2 Confidential Confidential Results of a oral range-finding study in female, non-pregnant Wistar rats
8EHQ-1012-18846A (PDF) 2-Propenoic acid, 4-[((4-benzoylphenoxy)carbonyl]oxy]butylester 131513-00-3 BASF Corporation Results of a toxicity study in Desmodesmus subspicatus
2-Butanone (MEK) *2,*3 78-93-3
8EHQ-1012-18847A (PDF) Confidential *2 Confidential Syngenta Crop Protection, LLC Results of an oral (gavage) prenatal developmental toxicity dose range finding study in the rat
8EHQ-1012-18848A (PDF) Confidential *2 Confidential Syngenta Crop Protection, LLC Results from a rat acute oral toxicity study
8EHQ-1012-18849A (PDF) 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane 2554-06-5 Silicones Environmental, Health and Safety Council Results of an in vitro mammalian chromosome aberration test in Chinese hamster V79 cells
8EHQ-1012-18850A (PDF) Fatty acids, tall-oil, reaction products with boric acid (H3BO3) and diethanolamine *1 91770-03-5 The Lubrizol Corporation Results of a local lymph node assay
8EHQ-1012-18851A (PDF) Bis(2,4-dichlorobenzoyl) peroxide 133-14-2 AkzoNobel Polymer Chemicals LLC Results of a 28-day study in rats
silicone oil 62129-63-9
8EHQ-1012-18852A (PDF) Vanadium 7440-62-2 Vanadium Producers & Reclaimers Association An abstract entitled "Are Inhabitants in "Vanadium Rich Area Healthy?: An Epidemiological Study on Inhabitants Consuming Vanadium-Rich-Tap-Water in Yamnashi Prefecture, Japan" and an abstract entitled: "Is Small Amount of Vanadium Intake from Drinking Water
8EHQ-1012-18853A (PDF) tert-amyl hydroperoxide 3425-61-4 Akzo Nobel Polymer Chemicals LLC Results of an OECD 487 in vitro mammalian cell micronucleus test
8EHQ-1012-18854A (PDF) Flourinated alkoxy derivative Confidential Confidential Results of a four-hour inhalation toxicity study in rats
8EHQ-1012-18855A (PDF) Chlorohydrofluoroether Confidential Confidential Results from a four-hour inhalation toxicity study in rats
8EHQ-1012-18856A (PDF) Fluoroalkylsulfuryl derivative Not provided Confidential Results of a four-hour inhalation toxicity test
8EHQ-1012-18857A (PDF) N,N-dimethyl- N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine (Triacetonetriamine TAT) 78014-16-1 Confidential Results of an Ames test
8EHQ-1012-18858A (PDF) E8-Quinolinol lithium salt (1:1) 25387-93-3 Dow Chemical Company Results of an algae and a fish study
8EHQ-1012-18859A (PDF) Dipropylene triamine 56-18-8 BASF Chemical Company Results of a Combined Repeated Dose Toxicity Study with the Reproduction/ Developmental Toxicity Screening Test
8EHQ-1012-18860A (PDF) 3-Methyl-1-phenyl-2-phospholene-1 -oxide 707-61-9 BASF Chemical Company Results of a Bovine Corneal Opacity and Permeability Test (BOOP Test)
8EHQ-1012-18861A (PDF) Substance A *2 Not provided Confidential Result of micronucleus screening test in vivo for two studies
8EHQ-1012-18862A (PDF) Substance B *2 Confidential Confidential Results of an acute oral screening in rats
Substance A *2 Confidential
Substance C *2 Confidential
Substance D *2 Confidential
8EHQ-1012-18863A (PDF) Substance I *2 Confidential Confidential Result of micronucleus screening test in vivo in mice
Substance II *2 Confidential    
8EHQ-1012-18864A (PDF) Halogenated Pyridine Derivative Not provided Dow Chemical Company Preliminary results of an aquatic plant study
8EHQ-1012-18865A (PDF) Halogenated Pyridine Derivative Not provided Dow Chemical Company Preliminary results of an aquatic plant
8EHQ-1012-18866A (PDF) Pyridine Derivative Not provided Dow Chemical Company Preliminary results of a shrimp and daphnid study
8EHQ-1012-18867A (PDF) Fatty acids, C1 6-18 and C1 8-unstad., Me esters, epoxidized, polymers with ethylene glycol. *1 918147-43-0 Confidential Results of a log Kow measurements on three substances
Substance 2 Confidential
Substance 1 Confidential
8EHQ-1012-18868A (PDF) Acrylonitrile *2 107-13-1 The Acrylonitrile Group Preliminary data from a DNA binding study
8EHQ-1012-18869A (PDF) Alkamuls VO/2003 220037-02-5 Rhodia Inc. Evaluation of skin sensitization potential in the mouse of alkamuls VO/2003 using the local lymph node assay
8EHQ-1012-18870A (PDF) Phenol, 4,4'-(1-methylethylidene)bis-, polymer with 5-amino-1,3,3-
trimethylcyclohexanemethanamine and 2-(chloromethyl)oxirane
38294-64-3 The Dow Chemical Company Results of a 14-day gavage toxicity study in rats
8EHQ-1012-18871A (PDF) Phenol, 4,4'-(1-methylethylidene)bis[2,6-dibromo-, polymer with 2-
chloromethyl)oxirane
40039-93-8 ICL-IP America Inc. Test summary of a 28-day oral toxicity study in rats
8EHQ-1012-18873A (PDF) 1,1,2,3,3,3 -hexafluoro-1,2-propanedisulfonyl difluoride (II) Not provided 3M Preliminary data from an acute inhalation toxicity study with rats
1,1,2,2,3,3 -hexafluoro-1,3-propanedisulfonyl difluoride (1) 82727-16-0
8EHQ-1012-18874A (PDF) Carbonodithioic acid, 0-(2-methylbutyl) S-2-propen--yl ester 1311195-87-5 Cytec Industries, Inc Preliminary results of an acute daphnid study
Carbonodithioic acid, 0-pentyl S-propenyl ester 2956-12-9
8EHQ-1012-18875A (PDF) Orasol Brown 2GL Multiple BASF Corporation Results of an acute toxicity study in Daphnia magna STRAUS
8EHQ-1012-18876A (PDF) 2-[[2-cyano-3-[4-(diethylamino)phenyl]-1-oxoallyl]oxy]ethyl][3-[[2-cyano-3-[4-(diethylamino)phenyl]-1-oxoallyl]oxy]propyl]dimethylammonium chloride 78181-99-4 BASF Corporation Results of a OECD 422 combined repeated dose toxicity study with the reproduction/ developmental toxicity screening test in rats
8EHQ-1012-18879A (PDF) Phosphorodithioic acid, O,O-bis(2-methylpropyl) ester, compd. with N, N dimethylmethanamine (1:1) 1354201-99-2 Cytec Industries Inc. Results from a local lymph node assay
8EHQ-1012-18883A (PDF) Tetramethylbisphenol diglycidyl ether Not provided Latham and Watkins Results of a Bacterial Reverse Mutation Assay
8EHQ-1012-18886A (PDF) Poly(oxy-1, 2-ethanediyl),. alpha., alpha.'-2- butyne- 1,4-d iylbis[. omega. -hyd roxy-(>1<4,5 mol EO) 32167-31-0 BASF Chemical Company Results of a repeated dose 28-day oral toxicity study in rats
8EHQ-1012-18891A (PDF) BAS 479 (Metazachlor), 2-chloro-N- (pyrazol-1-ylmethyl)acet-2',6'-xylidide, *2 67129-08-2 BASF Chemical Company Results of an aquatic study with Lemna minor
8EHQ-1012-18894A (PDF) Pigment Blue 15:2 *3 147-14-8 BASF Chemical Company Results of a skin sensitization study in mice
8EHQ-1012-18897A (PDF) Confidential Not provided Confidential Results of an EpiDerm™ Skin Corrosion Test
8EHQ-1012-18898A (PDF) 2-carbomethoxy-5-chloro- 1 -indanone *3 532-32-1 DuPont Haskell Global Centers for Health and Environmental Sciences Results of a BOD test
8EHQ-1012-18904A (PDF) Confidential *2 Confidential Bayer CropScience LP Exploratory 28-day toxicity study in the rat by dietary administration
8EHQ-1012-16995M (PDF) Confidential *2 Confidential Confidential Results of a 28 day dose range finding dietary immunotoxicity study and 28 dietary immunotoxicity study with rats
8EHQ-1012-16996M (PDF) Confidential *2 Confidential Confidential Results of a 28 day dose range finding dietary immunotoxicity study and a 28 day dietary immunotoxicity study with rats
8EHQ-1012-17027L (PDF) Confidential *2 Not provided Confidential Results of two dietary immunotoxicity studies with rats
8EHQ-1012-17081L (PDF) Confidential *2 Not provided Confidential Results of two 28 day dietary immunotoxicity studies with rats
8EHQ-1012-17209L (PDF) Confidential *2 Not provided Confidential Results of two dietary immunotoxicity studies with rats
8EHQ-1012-17297L (PDF) Confidential *2 Confidential Confidential Results of a 28-day dose range finding oral (dietary) immunotoxicity study in rats and a 28 day oral (dietary) immunotoxicity study in male rats.
8EHQ-1012-17866L (PDF) Confidential *2 Confidential Confidential Results of a 28-day dose range finding dietary immunotoxicity study with rats and a 28 day dietary immunotoxicity study with male rats.
8EHQ-1012-17907L (PDF) Confidential *2 Not provided Confidential Results of two dietary immunotoxicity studies in rats
8EHQ-1012-17958K (PDF) Confidential *2 Not provided Confidential Two 28 day dietary immunotoxicity study with rats
8EHQ-1012-18149B (PDF) Rosin, fumarated, polymer with petaerythritol 65997-11-7 Keller and Heckman LLP Results of a local lymph node assay
8EHQ-1012-18166K (PDF) Confidential *2 Confidential Confidential Results of a 28-day range-finding dietary immunotoxicity study and a 28-day dietary immunotoxicity study with rats
8EHQ-1012-18351B (PDF) Aerotech 2599   Kemira Chemicals, Inc. Results of acute toxicity studies in fathead minnows and Ceriodaphnia dubia
Colloid 1284      
8EHQ-1012-18714B (PDF) 2,5-dimethyl-2,5-di(2-ethylhexanoylperoxy) hexane 13052-09-0 Akzo Nobel Services Inc. Terminal summary results on an OECD 422 Combined Repeat Dose Toxicity with Reproduction/Developmental Toxicity Screening Test
8EHQ-1012-18819B (PDF) Carbonodithioic acid, O-pentyl S-propenyl ester 2956-12-9 Cytec Industries Inc Results of a local lymph node assay in the mouse
Carbonodithioic acid, O-(2-methylbutyl) S-2-propen-1-yl ester 1311195-87-5
Carbonodithioic acid, O-(2-methylbutyl) S-2-propen-1-yl ester 1311195-87-5
8EHQ-1012-18832B (PDF) Phosphonium, tributyltetradecyl-, chloride *2 81741-28-8 Cytec Industries Inc Results of an acute inhalation toxicity study in rats - limit test

*1 =  PMN;  *2  =  Pesticide;  * 3 = Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission.  8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s.  The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A).  The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
 
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters.  Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number.  Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information.  This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

Description - A general description of the type of study or information submitted, but not study results.  A PDF electronic copy of the submission is attached.


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