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Section 8(e) Substantial Risk Notifications and FYI Submissions Received February 2013

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8EHQ/FYI#
Chemical Name
CASRN
Submitter
Submission Description
8EHQ-0213-18985A (PDF) N-phenyl-, (tripropenyl) derivs 68608-79-7 DuPont Haskell Global Centers The results of a local lymph node assay (LLNA) with N-phenyl-, (tripropenyl) derivs. (CASRN 68608-79-7)
8EHQ-0213-18986A (PDF) Mixture containing the active ingredient 2-Propen-1-aminium, N, N-dimethyl-N-2-propen-1-yl-, chloride (1:1), polymer with ethanedial and 2-propenamide 32555-39-8 BASF The results of OECD 202 screening toxicity test in Daphnia Magna with a mixture containing the active ingredient 2-Propen-1-aminium, N, N-dimethyl-N-2-propen-1-yl-, chloride (1:1), polymer with ethanedial and 2-propenamide
CASRN 32555-39-8
8EHQ-0213-18987A (PDF) Benzylamine 100-46-9 BASF The results of a combined repeated dose toxicity study with the reproduction/ developmental toxicity screening test (OECD 422), in Wistar Rats with benzylamine, CAS No. 100-46-9
8EHQ-0213-18988A (PDF) Confidential *2 Confidential Confidential The results of repeated dose 90-day oral toxicity studies in Wistar rats with a developmental pesticide.
8EHQ-0213-18989A (PDF) Confidential *2 Confidential Confidential The results of a chronic toxicity test (NON-GLP indicator Study) on Collembola (Folsomia candida) with an experimental pesticide
8EHQ-0213-18990A (PDF) 2,4-dichloro-5-(chloromethyl)pyrimidine 7627-38-5 Confidential The results of a LLNA study in mice with 2,4-dichloro-5-(chloromethyl)pyrimidine CASRN 7627-38-5
8EHQ-0213-18991A (PDF) Phenol, 4-isocyanato-, 1,1', 1"-phosphorothioate 4151-51-3 Bayer material Science LLC The results of an acute inhalation toxicity study in rats with phenol, 4-isocyanato-, 1,1', 1"-phosphorothioate CASRN 4151-51-3
8EHQ-0213-18992A (PDF) Amines, bis (C11-14-branched and linear alkyl), tungstates *1 1159919-46-6 Confidential A final draft of an algal growth inhibition study ("Final Study") for one of the substances used in a Premanufacture Notice (PMN) submission identified as "Amines, bis (C11-14-branched and linear alkyl), tungstates (CASRN 1159919-46-6
8EHQ-0213-18993 (PDF) 1,3-Benzenedicarboxylic acid, 5-sulfo-,monosodium salt 6362-79-4 FutureFule Chemical Company The results of an OECD guideline 422 combined repeated dose toxicity study with the reproduction/developmental toxicity screeing test with 1,3-Benzenedicarboxylic acid, 5-sulfo-,monosodium salt (CASRN 6362-79-4)
8EHQ-0213-18994 (PDF) Confidential Confidential Confidential Information regarding a 13-week oral toxicity study in rats
8EHQ-0213-18995 (PDF) Generic Name: N-[[disubstituted-carbomonocycle)-(substituted-carbomonocycle)
Heteromonocycle]alkyl]heteromonocycle] carboxamide
Confidential Confidential The results of an AMES assay with Generic Name: N-[[disubstituted-carbomonocycle)-(substituted-carbomonocycle) Heteromonocycle]alkyl]heteromonocycle] carboxamide
8EHQ-0213-18996A (PDF) Confidential Confidential Confidential The results of a Bovine Corneal Opacity and Permeability Test (BCOP Test) with a substituted butyrolactam (A)
8EHQ-0213-18997A (PDF) Confidential Confidential Confidential The results of a Bovine Corneal Opacity and Permeability Test (BCOP Test) with a substituted butyrolactam (B)
8EHQ-0213-18998A (PDF) See PMN P-07-0164 *1 See File Huntsman Corporation The results from a combined repeated dose toxicity study with the reproductive/ development toxicity screening testing in rats.
8EHQ-0213-18999A (PDF) Confidential *2 Confidential Confidential The results of an acute toxicity study on honey bee (Apis mellifera) with a substituted lactone derivative.
8EHQ-0213-19000A (PDF) Confidential Confidential Confidential The results of a toxicity test on the growth of the green algae Pseudokirchneriella subcapitata with an agrochemical formulation containing a mixture two active ingredients.
8EHQ-0213-19001A (PDF) Butanedioic acid, sulfo-, 1-C12-18-alkyl esters, disodium salts 90268-36-3 BASF The results of a combined repeated dose toxicity study and reproduction/developmental toxicity screening test in rats with butanedioic acid, sulfo-, 1-C12-18-alkyl esters, disodium salts, (CASRN 90268-36-3)
8EHQ-0213-19002A (PDF) 1-Vinylimidazol 1072-63-5 BASF The results of a study in male and female rats (range finding, oral administration - gavage) with 1-Vinylimidazol, CASRN 1072-63-5.
8EHQ-0213-19003A (PDF) Carbonic acid, ethyl methyl ester, Ethylene carbonate, and Lithium hexafluorophosphate (1-), 623-53-0, 96-49-1, and 21324-40-3 BASF The results of an EpiDerm™ skin corrosion test with electrolyte LP 57
8EHQ-0213-19004A (PDF) cobalt lithium manganese nickel oxide 182442-95-1 BASF Information on 90-day inhalation study in rats with cobalt lithium manganese nickel oxide (CASRN 182442-95-1).
8EHQ-0213-19005A (PDF) 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-armethyl- 94270-86-7 BASF The results of a toxicity study in the unicellular freshwater green alga (Desmodesmus subspicatus) with 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-armethyl-, CASRN 94270-86-7
8EHQ-0213-19006A (PDF) Urea, N,N'-bis(hydroxymethyl)-, 140-95-4 BASF The results of a combined repeated dose toxicity study with the reproduction/ developmental toxicity screening test (OECD422) study with Urea, N,N'-bis(hydroxymethyl)-,CASRN 140-95-4
8EHQ-0213-19007A (PDF) 2,3-epoxypropyl neodecanoate 26761-45-5 Momentive Specialty Chemicals Inc. Final report on the induction of IacZ- mutations in the liver, kidney, bone marrow and spermatazoa of treated Muta™ Mice with  2,3-epoxypropyl neodecanoate, CASRN 26761-45-5
8EHQ-0213-19008A (PDF) Confidential Confidential Harlan The results of a sensitization study by Local Lymph Node Assay in mice
8EHQ-0213-19009A (PDF) Alkyl Ester Borate Not Provided Lubrizon Corporation Draft report of a combined 28-Day repeated dose rat oral (gavage) toxicity reproduction and developmental toxicity screen with all alkyl ester borate
8EHQ-0213-19010A (PDF) Phenol, 4,4'-(1-methylethylidene)bis-, polymer with 1,3-benzenedimethanamine and 2-(chloromethyl)oxirane 113930-69-1 Dow Chemical Company The results of a developmental toxicity study in rats after exposure to phenol, 4,4'-(1-methylethylidene)bis-, polymer with 1,3-benzenedimethanamine and 2-(chloromethyl)oxirane CASRN 113930-69-1
8EHQ-0213-19018A (PDF) Trihexyl(tetradecyl)phosphonium bis 2-ethylhexyl sulfosuccinate 1323126-03-9 Cytec The final report entitled "Fresh Water Algal Growth Inhibition Test" with Trihexyl(tetradecyl)phosphonium bis 2-ethylhexyl sulfosuccinate (CASRN 1323126-03-9)
FYI-0213-01703A (PDF) Formaldehyde, polymer with dimethylphenol and methylphenol, acetate 6-diazo-5, 6-dihydro-5-oxo- 1-naplithalenesulfonate 1361249-72-0 Shin-Etsu MicroSi, Inc. The final report Biodegradation study of RESJN-A2M (Formaldehyde, polymer with dimethylphenol and methylphenol, acetate 6-diazo-5, 6-dihydro-5-oxo- 1-naplithalenesulfonate (CASRN 1361249-72-0).
FYI-0213-01705A (PDF) Isobornyl acrylate (2-Propenoic acid, 1 ,7, 7-trimethylbicyclol[2.2.1 ]hept-2-yl ester, exo) 5888-33-5 Evonik Corporation The results from acute toxicity fish, Daphnia magna, algae,  and a LLNA report. with Isobornyl acrylate (2-Propenoic acid, 1,7, 7-trimethylbicyclol[2.2.1 ]hept-2-yl ester, exo) CASRN 5888-33-5.
FYI-0213-01706A (PDF) Ethyl triglycol methacrylate 39670-09-2 Evonik Corporation Information on toxic effects on rats after repeated oral dosing and  reproductive performance with ethyl triglycol methacrylate CASRN 39670-09-2.
FYI-0213-01707A (PDF) 1,4-Butanediol dimethacrylate 2082-81-7 Evonik Corporation Information on a repeated dosing and a developmental/reproductive study with 1,4-Butanediol dimethacrylate CASRN 2082-81-7.
FYI-0213-01708A (PDF) PFOA Not Provided DuPont Legal Information on a "Probable Link" between PFOA exposure among class members and any human diseases.
8EHQ-0213-00373DR (PDF) Perfluorooctanoic acid (PFOA) Multiple 3M Environmental, Health and Safety Operations The results from analysis of surface water and groundwater of perfluorooctanoic acid (PFOA) in the Decatur, Alabama area
8EHQ-0213-00373DS (PDF) perfluoroalkyl sulfonates (PFAS) including perfluorooctane sulfonate (PFOS) and nine other perfluoroalkyl carboxylates (PFCAs) Multiple 3M Environmental, Health and Safety Operations Results from 2011 Analyses of Four (4) perfluoroalkyl sulfonates (PFAS) including perfluorooctane sulfonate (PFOS) and nine other perfluoroalkyl carboxylates (PFCAs) in Fish and Surface Water from the Mississippi River
8EHQ-0213-00373DT (PDF) Perfluorooctanesulfonate 2795-39-3 3M Environmental, Health and Safety Operations Preliminary data from an 8-week dietary study in rats conducted on perfluorooctanesulfonate (PFOS) (CASRN 2795-39-3).
8EHQ-0213-16913I (PDF) 1-Octanol, 3,3,4,4,5,5,6,6,7,7, 8,8,8-tridecafluoro- 647-42-7 DuPont Haskell Global Centers The results of a 21-day Daphnia magna study with 1-Octanol, 3,3,4,4,5,5,6,6,7,7, 8,8,8-tridecafluoro- (CASRN 647-42-7)
8EHQ-0213-17181B (PDF) 1,1,1,2,2,3,3 -heptafluoro-3-methoxypropane 375-03-1 3M Environmental, Health and Safety Operations The results from an acute toxicity study in Daphnia magna performed on 1,1,1,2,2,3,3 -heptafluoro-3-methoxypropane (CASRN 375-03-1)
8EHQ-0213-18664C (PDF) Dioxopyrimidium inner salt Not Provided Confidential The results of acute oral and reproductive toxicity studies with dioxopyrimidium inner salt (Generic Name)
8EHQ-0213-18717C (PDF) Confidential Confidential Confidential The results of the human adrenocortical carcinoma (H295R) cell Steroidogenic Assay with Substituted Nitrogen Containing Heterocycle (Generic Name)
8EHQ-0213-18874B (PDF) Carbonodithioic acid, O-pentyl S-propenyl ester and Carbonodithioic acid, O-(2-methylbutyl) S-2-propen-l-yl ester 2956-12-9 and 1311195-87-5 Cytec The final report entitled "Daphnia sp., 48-hour Acute Immobilization Test" on a mixture identified as Carbonodithioic acid, O-pentyl S-propenyl ester (CASRN 2956-12-9) and Carbonodithioic acid, O-(2-methylbutyl) S-2-propen-l-yl ester (CASRN 1311195-87-5).
8EHQ-0213-18929B (PDF) Allyl Alcohol 107-18-6 LyondellBasell Industries The final report of an oral (gavage) dose range-finding prenatal developmental toxicity study of allyl alcohol in rabbits

*1 =  PMN;  *2  =  Pesticide;  * 3 = Pesticide Inert

DEFINITION OF TERMS

8EHQ# - This is the EPA submission number that includes a 4-digit month and year followed by a 5-digit number assigned sequentially from the year 1977, followed by a sequence letter ( “A” for the initial submission and “B”, “C”, “D”, etc. for supplemental submissions) (8EHQ-MMYY-XXXXX A). Supplemental means that it is a follow-up to an earlier submitted report.
Supplemental submissions reflect the month and year logged in but retain the same 5-digit sequential number as a link to the initial submission.  8EHQ number is a useful reference to request a copy of a submission.
FYI (For Your Information) submissions are the voluntary adjuncts of 8(e)s.  The FYI# is similar to that for 8(e) described above (FYI-MMYY-XXXXX A).  The submitter either judges that the information is not reportable under TSCA 8(e) reporting requirements or is not subject to TSCA 8(e) reporting but wants to share the information with EPA (and the public) on a voluntary basis.
 
NOTE that OPPT routinely sends follow-up requests to 8(e) submitters.  Other EPA programs and other federal agencies can ask OPPT to request follow-up information as well.

CHEM Name - This is the name used by the submitter.

CAS No. - The Chemical Abstracts Service Number.  Use of the term "CBI" indicates that the submitter is claiming the identity of the chemical to be confidential business information.  This claim can be challenged in some cases, and users should notify EPA if they wish to pursue the chemical identity.

Description - A general description of the type of study or information submitted, but not study results.  A PDF electronic copy of the submission is attached.


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