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Exposure Models and Assessments

This subject was discussed at the following meeting(s):

August 14 - 15, 2007: Review of EPA/ORD/NERL's SHEDS-Multimedia Model, Aggregate Version 3

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September 9-10, 2004 - Fumigant Bystander Exposure Model Review: SOil Fumigant Exposure Assessment System (SOFEA) Using Telone as a Case Study

August 26-27, 2004 - Fumigant Bystander Exposure Model Review: The Fumigant Exposure Modeling System (FEMS) Using Metam Sodium as a Case Study

August 24 - 25, 2004 - Fumigant Bystander Exposure Model Review: Probabilistic Exposure and Risk model for FUMigants (PERFUM) Using Iodomethane as a Case Study

Residential Exposure (REx) Model

August 30, 2002: Stochastic Human Exposure and Dose Simulation Model (SHEDS): System Operation Review of a Scenario Specific Model (SHEDS - Wood) to Estimate Children's Exposure and Dose to Wood Preservatives from Treated Playsets and Residential Decks Using EPA/ORD's SHEDS Probabilistic Model

Final Report (PDF) (36 pp, 203K, About PDF)
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September 26-29, 2000: Test Guidelines for Chronic Inhalation Toxicity and Carcinogenicity of Fibrous Particles; Cumulative Hazard Assessment of Organophosphorus Pesticides; Components and Methodologies of the Calendex™, Lifeline™, and REx Models as Tools for Dietary and Residential Pesticide Exposure and Risk Assessments; and Assessment of Pesticide Concentrations in Drinking Water and Water Treatment Effects on Pesticide Removal and Transformation

Final Reports

Session I - Test Guidelines for Chronic Inhalation Toxicity and Carcinogenicity of Fibrous Particles (PDF) (25 pp, 106K, About PDF)

Session II End Point Selection And Determination Of Relative Potency In Cumulative Hazard Assessment: A Pilot Study Of Organophosphorus Pesticide Chemicals (PDF) (34 pp, 210K, About PDF)

Sessions III-V (PDF) (35 pp, 80K, About PDF)

Session VI -Progress Report on Estimating Pesticide Concentrations in Drinking Water and Assessing Water Treatment Effects on Pesticide Removal and Transformation: A Consultation (PDF) (24 pp, 65K, About PDF)

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May 25-27, 1999: Office of Pesticide Programs Policy for the Use of the FQPA 10x Safety Factor; Statistical Methods for Use of Composite Data in Acute Dietary Exposure Assessment; Use of Watershed-derived Percent Crop Areas as Refinement Tool in FQPA Drinking Water Exposure Assessments for Tolerance Reassessment

Final Report (PDF) (72 pp, 370K, About PDF)
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February 23-24, 1999: Sediment Toxicity and Fate of Synthetic Pyrethroids, Time Sensitive Reversibility of Aldicarb Induced Cholinesterase Inhibition as a Factor in Acute Dietary Risk Assessment; and Consultation on Development of Draft Aggregate Exposure Assessment Guidance Document for Combining Exposure from Multiple Sources and Routes

Final Report (PDF) (48 pp, 134K, About PDF)
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March 24-25, 1998: Common Mechanism of Action of Organophosphates, Policy for Review of Monte Carlo Analysis for Dietary and Residential Exposure Scenarios, Suggested Probabilistic Risk Assessment Methodology for Evaluating Pesticides that exhibit a Common Mechanism of Action, Use of FQPA 10x Safety Factor to Address Special Sensitivity of Infants and Children to Pesticides, and Post Application Exposure Guidelines

Final Report
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September 9-10, 1997: FQPA Status Report; Criteria for Requiring In-utero Cancer Studies; Exposure Assessment Methodologies for Residential Scenarios; Progress Report on Developing Probabilistic Risk Assessment Methodologies for Aquatic and Terrestrial Risk; Efficacy Testing Issues Concerning Public Health Antimicrobial Pesticides

Final Report
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June 3-4, 1997: Anticipated Residues Methodology; Import Tolerance Guidelines; Antimicrobial Issues; Cholinesterase Policy Issues; DEET Risk Assessment (N,N - diethyl-meta -toluamide)

Final Report (PDF) (31 pp, 84K, About PDF)
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March 19-20, 1997: Toxicology Endpoint Selection Process; Inhalation Risk Assessments and the Combining of Margin of Exposures; Aggregate Exposure Methodology Issues; Common Mechanism of Action; Visual System Toxicity Testing of Organophosphates

Final Report (PDF) (35 pp, 167K, About PDF)
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