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  • Acute Dose-Response
  • Ambient Water Quality Criteria
  • Applicable or Relevant and Appropriate Requirements (ARARs)
  • Arsenic
  • Asbestos
  • Background Contamination
  • Benchmark Dose
  • Bioavailability of Soil
  • Biokinetic Model for Lead (IEUBK)
  • Biological Technical Assistance Group (BTAG)
  • Cancer Risk Assessment
  • Chemical Mixtures
  • Children’s Health
  • Cumulative Risk Assessment
  • Clean-Up Levels
  • Community Guides
  • Data Usability Guidance
  • Dioxin
  • Drinking Water
  • Ecological: Planning and Scoping
  • Ecological: Problem Formulation
  • Ecological Risk Assessment
  • Ecological: Risk Characterization
  • Ecological: Stressor Response and Exposure Analysis
  • ECO Update Bulletin Series
  • Exposure Factor Handbook
  • Human Health: Acute Hazards
  • Human Health: Exposure Assessment
  • Human Health: Planning and Scoping
  • Human Health: Risk Characterization
  • Human Health: Toxicity (Hazard Identification and Dose Response)
  • Inhalation Toxicity
  • Integrated Risk Information System (IRIS)
  • Lead
  • Mercury
  • Metals
  • Natural Resource Trustees
  • Non-Cancer Risk Assessment (Rfd)
  • Peer Review
  • Pesticides
  • Policy Guidance Documents
  • Polychlorinated Biphenyls (PCB)
  • Polycyclic Aromatic Hydrocarbons (PAHs)
  • Probabilistic Analysis
  • PRP Risk Assessments
  • Radiation Risk Assessment
  • RBCA Fate and Transport Models
  • Risk Assessment Guidance (RAGs)
  • Risk-based Decision Making
  • Risk Characterization
  • Risk Communication
  • Risk Management
  • Science Policy Council
  • Screening Level Assessments
  • Superfund Guidance
  • Technical Assistance Grants (TAGs)
  • Toxicity Values
  • Toxicological Guidance (ORD)
  • Underground Storage Tanks
  • Vapor Intrusion
  • Volatiles

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    • Mercury
      Mercury is a heavy, silvery-white metal.

      This mercury site provides a broad range of information: actions by EPA and others, including international actions; effects on people and the environment; and how to protect you and your family.

      Mercury IRIS Summary

      Task Force on Ritualistic Uses of Mercury
      (111 pp, 979K, About PDF)

    • Metals
      A metal is an element, compound, or alloy characterized by high electrical conductivity.

      Framework for Metals Risk Assessment
      March 2007
      The Framework seeks to advance our understanding of the impact of metals in a consistent manner across the Agency's programs since inorganic metals and metal compounds present unique issues for risk assessors.

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    • Technical Assistance Grants (TAGs)
      Provide money for activities that help your community participate in decision making at eligible Superfund sites.

      Technical Assistance Grants (TAGs)

    • Toxicity Values
      The numerical values in units of exposure that relate to specific toxic risk level considering all know toxic effects of a substance.

      Integrated Risk Information System (IRIS)
      IRIS is a compilation of electronic reports on specific substances found in the environment and their potential to cause human health effects.

      Human Health Toxicity Values in Superfund Risk Assessments
      (4 pp, 228K, About PDF) OSWER Directive 9285.7-53, December 2003

    • Toxicological Guidance (ORD)
      Guidance documents that provide EPA’s recommendations to Agency risk assessors on preparing risk assessments that consider specific toxicological effects.

      Guidelines for Carcinogen Risk Assessment
      The Guidelines provide a framework to EPA scientists for assessing possible cancer risks from exposures to pollutants or other agents in the environment. They will also inform Agency decision makers and the public about these recommended procedures.

      Guidelines for Developmental Toxicity Risk Assessment (PDF)
      (83 pp, 192K, About PDF) Federal Register 56(234):63798-63826, 1991
      These guidelines outline principles and methods for evaluating data from animal and human studies, exposure data, and other information to characterize risk to human development, growth, survival, and function because of exposure prior to conception, prenatally, or to infants and children.

      Guidelines for Mutagenicity Risk Assessment (PDF)
      (23 pp, 256K, About PDF) Federal Register 51(185):34006-34012, 1986
      The Guidelines for Mutagenicity Risk Assessment are intended to guide Agency analysis of mutagenicity data in line with the policies and procedures established in the statutes administered by EPA.

      Guidelines for Neurotoxicity Risk Assessment (PDF)
      (89 pp, 184K, About PDF) Federal Register 63(93):26926-26954, 1998
      These Guidelines are intended to guide Agency evaluation of agents that are suspected to cause neurotoxicity, in line with the policies and procedures established in the statutes administered by the Agency.

      Guidelines for Reproductive Toxicity Risk Assessment (PDF)
      (143 pp, 324K, About PDF) Federal Register 61(212):56274-56322, 1996
      This notice describes the scientific basis for concern about exposure to agents that cause reproductive toxicity, outlines the general process for assessing potential risk to humans from exposure to environmental agents, and addresses Science Advisory Board and public comments on the 1994 Proposed Guidelines for Reproductive Toxicity Risk Assessment.

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    • Vapor Intrusion
      Tthe migration of volatile chemicals from the subsurface into overlying buildings

      Vapor Intrusion Guidance (PDF)
      (178 pp, 1.9MB, About PDF)
      OSWER Draft Guidance for Evaluating the Vapor Intrusion to Indoor Air Pathway from Groundwater and Soils (Subsurface Vapor Intrusion Guidance). Provides current technical and policy recommendations on determining if the vapor intrusion pathway poses an unacceptable risk to human health at clean-up sites.

      Johnson and Ettinger Model for Subsurface Vapor Intrusion into Buildings
      Concerns have been raised about the potential for subsurface contamination in either soil or ground water adversely impacting indoor air quality. In September 1998, EPA developed a series of models for estimating indoor air concentrations and associated health risks from subsurface vapor intrusion into buildings.

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