RCRA Risk Assessment: Human Health: Risk Characterization
RCRA Human Health
Risk Topics:
Toxicity (Hazard Identification and Dose Response)
Risk Characterization
In Risk Characterization, the information from Hazard Identification, Exposure Assessment, Dose-Response Assessment are summarized and integrated into quantitative and qualitative expressions of risk. To estimate potential noncarcinogenic effects, comparisons are made between projected intakes of substances and toxicity values; to estimate potential carcinogenic effects, probabilities that an individual will develop cancer over a lifetime of exposure are determined from projected intakes and chemical-specific dose-response information. Major assumptions, scientific judgments, and to the extent possible, estimates of the uncertainties embodied in the assessment are also presented.
- Integrated
Exposure Uptake Biokinetic Model for Lead in Children (IEUBK)
The Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) attempts to predict blood-lead concentrations (PbBs) for children exposed to lead in their environment. The model allows the user to input relevant absorption parameters (e.g., the fraction of lead absorbed from water) as well as intake and exposure rates.
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