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Frequent Questions and EPA Response Documents

This page provides links to questions and answers on the Cancer Guidelines and Supplemental Guidance documents, as well as a summary of EPA’s reponses to comments on the draft reports. If you do not find the question or answer you're looking for, please contact us.

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Questions and Answers

Questions and Answers: EPA’s Guidelines for Carcinogen Risk Assessment and Supplemental Guidance from Assessing Susceptibility from Early-Life Exposure to Carcinogens (March 29, 2005)
Questions and answers providing general information and a summary of key points in EPA’s "Guidelines for Carcinogen Risk Assessment".

Fact Sheets with Frequent Questions

Fact Sheet: Implementation of the Supplemental Guidance in Cancer Risk Assessment (PDF) (5 pp, 48K) (June 2006)
Many questions on implementation of the 2005 Cancer Guidelines and Supplemental Guidance have been asked or can be anticipated. This Fact Sheet was created as a tool for risk assessors and provides information that may be useful for communication with the public.

Responses to Comments

EPA’s Summary Response to Public Comments on EPA’s Draft Cancer Risk Assessment Guidelines of 1996, 1999, and 2003 (PDF) (21 pp, 98K) (March 28, 2005)
This summary response to public comments covers comments received on three distinct drafts of proposed revisions to EPA’s cancer guidelines and focuses on the major themes that were raised over the years and the responses to them that often resulted in significant and substantial changes in the guidelines.

EPA’s Summary Response to Comments on EPA’s Draft Supplemental Guidance (PDF) (20 pp, 117K) (March 28, 2005)
Summarizes the major issues raised by public reviewers and the Environmental Health Committee of EPA’s Science Advisory Board (SAB) in 2003.

EPA’s Response to the SAB [Science Advisory Board] Review Panel's Recommendations on the Draft Supplemental Guidance for Assessing Cancer Susceptibility from Early-Life Exposure to Carcinogens (PDF) (7 pp, 40K) (September 1, 2004)
EPA’s response to the Science Advisory Board Panel’s Summary of Recommendations.

Note: The SAB’s recommendations can be found here - Science Advisory Board’s Review of EPA’s Draft Supplemental Guidance For Assessing Cancer Susceptibility From Early-Life Exposure to Carcinogens (PDF) (40 pp, 347K) (EPA-SAB-04-003, March 3, 2004)

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